SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '1fb1'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4RVG_A_SAMA503_0
(D-MYCAROSE
3-C-METHYLTRANSFERAS
E)		 1fb1 GTP CYCLOHYDROLASE I
(Homo
sapiens) 		5 / 12 THR A 225
ILE A 189
VAL A 152
HIS A 153
ILE A 154
 None
 1.07A 4rvgA-1fb1A:
undetectable		 4rvgA-1fb1A:
18.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5TJZ_A_BEZA302_0
(4-HYDROXY-TETRAHYDRO
DIPICOLINATE
REDUCTASE)		 1fb1 GTP CYCLOHYDROLASE I
(Homo
sapiens) 		3 / 3 MET A 230
GLU A 242
ARG A 241
 None
 1.00A 5tjzA-1fb1A:
undetectable		 5tjzA-1fb1A:
21.15