SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '1fba'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1BDW_B_DVAB6_0
(GRAMICIDIN A)		 1fba FRUCTOSE
1,6-BISPHOSPHATE
ALDOLASE
(Drosophila
melanogaster) 		3 / 3 TRP A 313
ALA A 322
VAL A 309
 None
 0.96A 1bdwA-1fbaA:
undetectable
1bdwB-1fbaA:
undetectable		 1bdwA-1fbaA:
3.78
1bdwB-1fbaA:
3.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1FBM_B_RTLB951_1
(PROTEIN (CARTILAGE
OLIGOMERIC MATRIX
PROTEIN))		 1fba FRUCTOSE
1,6-BISPHOSPHATE
ALDOLASE
(Drosophila
melanogaster) 		4 / 4 THR A 205
LEU A 209
VAL A 212
LEU A 216
 None
 0.44A 1fbmB-1fbaA:
undetectable		 1fbmB-1fbaA:
9.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1FBM_B_RTLB951_2
(PROTEIN (CARTILAGE
OLIGOMERIC MATRIX
PROTEIN))		 1fba FRUCTOSE
1,6-BISPHOSPHATE
ALDOLASE
(Drosophila
melanogaster) 		4 / 4 THR A 205
LEU A 209
VAL A 212
LEU A 216
 None
 0.62A 1fbmD-1fbaA:
0.0		 1fbmD-1fbaA:
9.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1FBM_B_RTLB951_3
(PROTEIN (CARTILAGE
OLIGOMERIC MATRIX
PROTEIN))		 1fba FRUCTOSE
1,6-BISPHOSPHATE
ALDOLASE
(Drosophila
melanogaster) 		4 / 5 THR A 205
LEU A 209
VAL A 212
LEU A 216
 None
 0.48A 1fbmE-1fbaA:
undetectable		 1fbmE-1fbaA:
9.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GSF_A_EAAA223_1
(GLUTATHIONE
TRANSFERASE A1-1)		 1fba FRUCTOSE
1,6-BISPHOSPHATE
ALDOLASE
(Drosophila
melanogaster) 		4 / 8 PHE A 357
GLY A 272
LEU A 270
VAL A 150
 None
 0.97A 1gsfA-1fbaA:
0.0		 1gsfA-1fbaA:
19.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GSF_B_EAAB223_1
(GLUTATHIONE
TRANSFERASE A1-1)		 1fba FRUCTOSE
1,6-BISPHOSPHATE
ALDOLASE
(Drosophila
melanogaster) 		4 / 8 PHE A 357
GLY A 272
LEU A 270
VAL A 150
 None
 0.97A 1gsfB-1fbaA:
0.0		 1gsfB-1fbaA:
19.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GSF_C_EAAC223_1
(GLUTATHIONE
TRANSFERASE A1-1)		 1fba FRUCTOSE
1,6-BISPHOSPHATE
ALDOLASE
(Drosophila
melanogaster) 		4 / 8 PHE A 357
GLY A 272
LEU A 270
VAL A 150
 None
 0.97A 1gsfC-1fbaA:
0.0		 1gsfC-1fbaA:
19.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GSF_D_EAAD223_1
(GLUTATHIONE
TRANSFERASE A1-1)		 1fba FRUCTOSE
1,6-BISPHOSPHATE
ALDOLASE
(Drosophila
melanogaster) 		4 / 8 PHE A 357
GLY A 272
LEU A 270
VAL A 150
 None
 0.97A 1gsfD-1fbaA:
0.0		 1gsfD-1fbaA:
19.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1JOM_A_FFOA161_0
(DIHYDROFOLATE
REDUCTASE)		 1fba FRUCTOSE
1,6-BISPHOSPHATE
ALDOLASE
(Drosophila
melanogaster) 		5 / 11 GLU A 187
LEU A 270
ILE A 185
TYR A 213
THR A 205
 None
 1.18A 1jomA-1fbaA:
undetectable		 1jomA-1fbaA:
19.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1MX1_E_THAE5_2
(LIVER
CARBOXYLESTERASE I)		 1fba FRUCTOSE
1,6-BISPHOSPHATE
ALDOLASE
(Drosophila
melanogaster) 		3 / 3 PHE A  63
LEU A  78
LEU A 104
 None
 0.55A 1mx1E-1fbaA:
undetectable		 1mx1E-1fbaA:
22.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1MZ9_D_VDYD1001_3
(CARTILAGE OLIGOMERIC
MATRIX PROTEIN)		 1fba FRUCTOSE
1,6-BISPHOSPHATE
ALDOLASE
(Drosophila
melanogaster) 		3 / 3 THR A 205
LEU A 209
LEU A 216
 None
 0.63A 1mz9C-1fbaA:
undetectable		 1mz9C-1fbaA:
8.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1MZ9_D_VDYD1001_4
(CARTILAGE OLIGOMERIC
MATRIX PROTEIN)		 1fba FRUCTOSE
1,6-BISPHOSPHATE
ALDOLASE
(Drosophila
melanogaster) 		4 / 4 THR A 205
LEU A 209
VAL A 212
LEU A 216
 None
 0.60A 1mz9D-1fbaA:
undetectable		 1mz9D-1fbaA:
8.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1SV5_A_65BA600_0
(REVERSE
TRANSCRIPTASE)		 1fba FRUCTOSE
1,6-BISPHOSPHATE
ALDOLASE
(Drosophila
melanogaster) 		5 / 10 LEU A 209
VAL A 264
VAL A 186
PRO A 294
LEU A 256
 None
 1.25A 1sv5A-1fbaA:
0.0		 1sv5A-1fbaA:
21.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1YA4_C_CTXC1383_1
(CES1 PROTEIN)		 1fba FRUCTOSE
1,6-BISPHOSPHATE
ALDOLASE
(Drosophila
melanogaster) 		4 / 5 TRP A 295
PRO A 261
LEU A 223
GLY A 225
 None
 1.30A 1ya4C-1fbaA:
0.7		 1ya4C-1fbaA:
22.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2W1B_A_DXCA2034_0
(ACRIFLAVIN
RESISTANCE PROTEIN B)		 1fba FRUCTOSE
1,6-BISPHOSPHATE
ALDOLASE
(Drosophila
melanogaster) 		3 / 3 PHE A 144
SER A 300
LEU A  30
 None
 0.75A 2w1bA-1fbaA:
0.0		 2w1bA-1fbaA:
16.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2YVL_D_SAMD603_0
(HYPOTHETICAL PROTEIN)		 1fba FRUCTOSE
1,6-BISPHOSPHATE
ALDOLASE
(Drosophila
melanogaster) 		5 / 12 THR A 298
GLY A  28
ALA A  24
ALA A  31
ASP A  33
 None
 1.13A 2yvlD-1fbaA:
undetectable		 2yvlD-1fbaA:
22.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3AOD_C_RFPC2002_1
(ACRIFLAVINE
RESISTANCE PROTEIN B)		 1fba FRUCTOSE
1,6-BISPHOSPHATE
ALDOLASE
(Drosophila
melanogaster) 		5 / 12 GLN A 178
PHE A 144
ALA A 145
THR A 226
ARG A 181
 None
 1.49A 3aodC-1fbaA:
0.0		 3aodC-1fbaA:
16.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3H52_B_486B1_2
(GLUCOCORTICOID
RECEPTOR)		 1fba FRUCTOSE
1,6-BISPHOSPHATE
ALDOLASE
(Drosophila
melanogaster) 		5 / 12 GLY A 225
GLN A 178
VAL A 183
LEU A 216
ILE A  22
 None
 1.26A 3h52B-1fbaA:
undetectable		 3h52B-1fbaA:
22.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KKZ_A_SAMA301_0
(UNCHARACTERIZED
PROTEIN Q5LES9)		 1fba FRUCTOSE
1,6-BISPHOSPHATE
ALDOLASE
(Drosophila
melanogaster) 		5 / 12 GLY A 273
LEU A 270
GLU A 276
ALA A 279
ASN A 282
 None
 1.09A 3kkzA-1fbaA:
undetectable		 3kkzA-1fbaA:
21.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3OHT_A_1N1A1000_2
(P38A)		 1fba FRUCTOSE
1,6-BISPHOSPHATE
ALDOLASE
(Drosophila
melanogaster) 		3 / 3 GLU A 187
LEU A 270
LEU A  30
 None
 0.77A 3ohtA-1fbaA:
undetectable		 3ohtA-1fbaA:
19.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3OHT_B_1N1B1000_2
(P38A)		 1fba FRUCTOSE
1,6-BISPHOSPHATE
ALDOLASE
(Drosophila
melanogaster) 		3 / 3 GLU A 187
LEU A 270
LEU A  30
 None
 0.74A 3ohtB-1fbaA:
undetectable		 3ohtB-1fbaA:
19.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4EJ1_B_FOLB201_0
(DIHYDROFOLATE
REDUCTASE)		 1fba FRUCTOSE
1,6-BISPHOSPHATE
ALDOLASE
(Drosophila
melanogaster) 		5 / 12 GLU A 187
LEU A 270
ILE A 185
TYR A 213
THR A 205
 None
 1.14A 4ej1B-1fbaA:
undetectable		 4ej1B-1fbaA:
19.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4IB4_A_ERMA2001_2
(CHIMERA PROTEIN OF
HUMAN
5-HYDROXYTRYPTAMINE
RECEPTOR 2B AND E.
COLI SOLUBLE
CYTOCHROME B562)		 1fba FRUCTOSE
1,6-BISPHOSPHATE
ALDOLASE
(Drosophila
melanogaster) 		4 / 7 THR A 259
LEU A 151
ASN A 231
LEU A 270
 None
 1.01A 4ib4A-1fbaA:
undetectable		 4ib4A-1fbaA:
23.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4UUU_A_SAMA1546_0
(CYSTATHIONINE
BETA-SYNTHASE)		 1fba FRUCTOSE
1,6-BISPHOSPHATE
ALDOLASE
(Drosophila
melanogaster) 		5 / 11 LEU A 356
GLN A 306
ALA A 307
ILE A  77
ASP A  33
 None
 1.27A 4uuuA-1fbaA:
0.0
4uuuB-1fbaA:
0.0		 4uuuA-1fbaA:
17.89
4uuuB-1fbaA:
17.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4UUU_B_SAMB1548_0
(CYSTATHIONINE
BETA-SYNTHASE)		 1fba FRUCTOSE
1,6-BISPHOSPHATE
ALDOLASE
(Drosophila
melanogaster) 		5 / 11 LEU A 356
GLN A 306
ALA A 307
ILE A  77
ASP A  33
 None
 1.23A 4uuuB-1fbaA:
0.0		 4uuuB-1fbaA:
17.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4WG0_C_CHDC102_0
(NUCLEAR RECEPTOR
COACTIVATOR 2)		 1fba FRUCTOSE
1,6-BISPHOSPHATE
ALDOLASE
(Drosophila
melanogaster) 		4 / 7 LYS A  98
LEU A  97
LEU A 104
LEU A  78
 None
 0.78A 4wg0B-1fbaA:
undetectable
4wg0C-1fbaA:
undetectable		 4wg0B-1fbaA:
5.58
4wg0C-1fbaA:
5.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4WG0_I_CHDI103_0
(NUCLEAR RECEPTOR
COACTIVATOR 2)		 1fba FRUCTOSE
1,6-BISPHOSPHATE
ALDOLASE
(Drosophila
melanogaster) 		5 / 11 GLU A  95
LYS A  98
LEU A  97
LEU A 104
LEU A  78
 None
 1.16A 4wg0G-1fbaA:
undetectable
4wg0H-1fbaA:
undetectable
4wg0I-1fbaA:
undetectable		 4wg0G-1fbaA:
5.58
4wg0H-1fbaA:
5.58
4wg0I-1fbaA:
5.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5AMI_B_EF2B151_1
(CEREBLON ISOFORM 4)		 1fba FRUCTOSE
1,6-BISPHOSPHATE
ALDOLASE
(Drosophila
melanogaster) 		4 / 8 ASN A 231
PRO A 230
PHE A 269
SER A 271
 None
 1.43A 5amiB-1fbaA:
undetectable		 5amiB-1fbaA:
15.85