SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '1fbl'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site

Query pattern: Residues from known binding site for annotated drug that match the hit pattern


(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID
Hit
Macromolecule
Res.
Matches
Interface HETATM RMSD Dali
Z-score
Seq.
Identity (%)
View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1FML_A_RTLA401_0
(RETINOL DEHYDRATASE)
1fbl FIBROBLAST
(INTERSTITIAL)
COLLAGENASE (MMP-1)

(Sus
scrofa)
5 / 12 LEU A 226
LEU A 102
LEU A 147
ILE A 256
PHE A 138
None
1.28A 1fmlA-1fblA:
0.5
1fmlA-1fblA:
21.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1OS2_A_HAEA874_1
(MACROPHAGE
METALLOELASTASE)
1fbl FIBROBLAST
(INTERSTITIAL)
COLLAGENASE (MMP-1)

(Sus
scrofa)
5 / 5 HIS A 183
HIS A 218
GLU A 219
HIS A 222
HIS A 228
ZN  A 997 (-3.2A)
ZN  A 998 ( 3.5A)
HTA  A 900 (-3.0A)
ZN  A 998 ( 3.8A)
ZN  A 998 ( 3.6A)
0.43A 1os2A-1fblA:
28.0
1os2A-1fblA:
27.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1OS2_D_HAED574_1
(MACROPHAGE
METALLOELASTASE)
1fbl FIBROBLAST
(INTERSTITIAL)
COLLAGENASE (MMP-1)

(Sus
scrofa)
4 / 4 HIS A 218
GLU A 219
HIS A 222
HIS A 228
ZN  A 998 ( 3.5A)
HTA  A 900 (-3.0A)
ZN  A 998 ( 3.8A)
ZN  A 998 ( 3.6A)
0.45A 1os2D-1fblA:
28.0
1os2D-1fblA:
27.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1QVT_A_PRLA311_0
(TRANSCRIPTIONAL
REGULATOR QACR)
1fbl FIBROBLAST
(INTERSTITIAL)
COLLAGENASE (MMP-1)

(Sus
scrofa)
4 / 8 GLU A 135
THR A 115
TYR A 116
TYR A 121
None
1.15A 1qvtA-1fblA:
undetectable
1qvtA-1fblA:
18.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1SGU_B_MK1B2632_1
(POL POLYPROTEIN)
1fbl FIBROBLAST
(INTERSTITIAL)
COLLAGENASE (MMP-1)

(Sus
scrofa)
5 / 8 ILE A 191
GLY A 192
GLY A 193
ILE A 159
ALA A 182
None
CA  A 995 (-4.3A)
CA  A 995 ( 4.9A)
None
None
1.31A 1sguA-1fblA:
undetectable
1sguA-1fblA:
14.59
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1UTT_A_HAEA1265_1
(MACROPHAGE
METALLOELASTASE)
1fbl FIBROBLAST
(INTERSTITIAL)
COLLAGENASE (MMP-1)

(Sus
scrofa)
4 / 4 HIS A 218
GLU A 219
HIS A 222
HIS A 228
ZN  A 998 ( 3.5A)
HTA  A 900 (-3.0A)
ZN  A 998 ( 3.8A)
ZN  A 998 ( 3.6A)
0.41A 1uttA-1fblA:
28.0
1uttA-1fblA:
37.55
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1UTZ_A_HAEA1267_1
(MACROPHAGE
METALLOELASTASE)
1fbl FIBROBLAST
(INTERSTITIAL)
COLLAGENASE (MMP-1)

(Sus
scrofa)
4 / 4 HIS A 218
GLU A 219
HIS A 222
HIS A 228
ZN  A 998 ( 3.5A)
HTA  A 900 (-3.0A)
ZN  A 998 ( 3.8A)
ZN  A 998 ( 3.6A)
0.46A 1utzA-1fblA:
27.9
1utzA-1fblA:
37.55
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1UTZ_B_HAEB1266_1
(MACROPHAGE
METALLOELASTASE)
1fbl FIBROBLAST
(INTERSTITIAL)
COLLAGENASE (MMP-1)

(Sus
scrofa)
4 / 4 HIS A 218
GLU A 219
HIS A 222
HIS A 228
ZN  A 998 ( 3.5A)
HTA  A 900 (-3.0A)
ZN  A 998 ( 3.8A)
ZN  A 998 ( 3.6A)
0.47A 1utzB-1fblA:
28.0
1utzB-1fblA:
37.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1WRL_F_TFPF211_1
(TROPONIN C, SLOW
SKELETAL AND CARDIAC
MUSCLES)
1fbl FIBROBLAST
(INTERSTITIAL)
COLLAGENASE (MMP-1)

(Sus
scrofa)
4 / 7 LEU A 294
PHE A 284
PHE A 430
PHE A 439
None
0.91A 1wrlE-1fblA:
undetectable
1wrlF-1fblA:
undetectable
1wrlE-1fblA:
15.19
1wrlF-1fblA:
15.19
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1Y93_A_HAEA301_1
(MACROPHAGE
METALLOELASTASE)
1fbl FIBROBLAST
(INTERSTITIAL)
COLLAGENASE (MMP-1)

(Sus
scrofa)
5 / 6 HIS A 183
HIS A 218
GLU A 219
HIS A 222
HIS A 228
ZN  A 997 (-3.2A)
ZN  A 998 ( 3.5A)
HTA  A 900 (-3.0A)
ZN  A 998 ( 3.8A)
ZN  A 998 ( 3.6A)
0.43A 1y93A-1fblA:
27.7
1y93A-1fblA:
37.02
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2HU6_A_HAEA269_1
(MACROPHAGE
METALLOELASTASE)
1fbl FIBROBLAST
(INTERSTITIAL)
COLLAGENASE (MMP-1)

(Sus
scrofa)
4 / 4 HIS A 218
GLU A 219
HIS A 222
HIS A 228
ZN  A 998 ( 3.5A)
HTA  A 900 (-3.0A)
ZN  A 998 ( 3.8A)
ZN  A 998 ( 3.6A)
0.41A 2hu6A-1fblA:
27.9
2hu6A-1fblA:
37.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2JIH_A_097A1001_1
(ADAMTS-1)
1fbl FIBROBLAST
(INTERSTITIAL)
COLLAGENASE (MMP-1)

(Sus
scrofa)
5 / 9 LEU A 181
HIS A 218
GLU A 219
HIS A 222
HIS A 228
HTA  A 900 (-3.6A)
ZN  A 998 ( 3.5A)
HTA  A 900 (-3.0A)
ZN  A 998 ( 3.8A)
ZN  A 998 ( 3.6A)
0.39A 2jihA-1fblA:
8.4
2jihA-1fblA:
20.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2JIH_B_097B1001_1
(ADAMTS-1)
1fbl FIBROBLAST
(INTERSTITIAL)
COLLAGENASE (MMP-1)

(Sus
scrofa)
5 / 8 LEU A 181
HIS A 218
GLU A 219
HIS A 222
HIS A 228
HTA  A 900 (-3.6A)
ZN  A 998 ( 3.5A)
HTA  A 900 (-3.0A)
ZN  A 998 ( 3.8A)
ZN  A 998 ( 3.6A)
0.41A 2jihB-1fblA:
9.8
2jihB-1fblA:
20.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2OW9_A_HAEA502_1
(COLLAGENASE 3)
1fbl FIBROBLAST
(INTERSTITIAL)
COLLAGENASE (MMP-1)

(Sus
scrofa)
5 / 6 HIS A 183
HIS A 218
GLU A 219
HIS A 222
HIS A 228
ZN  A 997 (-3.2A)
ZN  A 998 ( 3.5A)
HTA  A 900 (-3.0A)
ZN  A 998 ( 3.8A)
ZN  A 998 ( 3.6A)
0.51A 2ow9A-1fblA:
27.6
2ow9A-1fblA:
29.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2OW9_B_HAEB502_1
(COLLAGENASE 3)
1fbl FIBROBLAST
(INTERSTITIAL)
COLLAGENASE (MMP-1)

(Sus
scrofa)
4 / 4 HIS A 218
GLU A 219
HIS A 222
HIS A 228
ZN  A 998 ( 3.5A)
HTA  A 900 (-3.0A)
ZN  A 998 ( 3.8A)
ZN  A 998 ( 3.6A)
0.46A 2ow9B-1fblA:
27.5
2ow9B-1fblA:
29.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2OZR_C_HAEC3001_1
(COLLAGENASE 3)
1fbl FIBROBLAST
(INTERSTITIAL)
COLLAGENASE (MMP-1)

(Sus
scrofa)
4 / 4 HIS A 218
GLU A 219
HIS A 222
HIS A 228
ZN  A 998 ( 3.5A)
HTA  A 900 (-3.0A)
ZN  A 998 ( 3.8A)
ZN  A 998 ( 3.6A)
0.48A 2ozrC-1fblA:
27.8
2ozrC-1fblA:
29.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2OZR_D_HAED3002_1
(COLLAGENASE 3)
1fbl FIBROBLAST
(INTERSTITIAL)
COLLAGENASE (MMP-1)

(Sus
scrofa)
4 / 4 HIS A 218
GLU A 219
HIS A 222
HIS A 228
ZN  A 998 ( 3.5A)
HTA  A 900 (-3.0A)
ZN  A 998 ( 3.8A)
ZN  A 998 ( 3.6A)
0.43A 2ozrD-1fblA:
28.1
2ozrD-1fblA:
29.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2OZR_E_HAEE3003_1
(COLLAGENASE 3)
1fbl FIBROBLAST
(INTERSTITIAL)
COLLAGENASE (MMP-1)

(Sus
scrofa)
4 / 4 HIS A 218
GLU A 219
HIS A 222
HIS A 228
ZN  A 998 ( 3.5A)
HTA  A 900 (-3.0A)
ZN  A 998 ( 3.8A)
ZN  A 998 ( 3.6A)
0.34A 2ozrE-1fblA:
27.6
2ozrE-1fblA:
29.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2OZR_F_HAEF3004_1
(COLLAGENASE 3)
1fbl FIBROBLAST
(INTERSTITIAL)
COLLAGENASE (MMP-1)

(Sus
scrofa)
3 / 3 HIS A 218
HIS A 222
HIS A 228
ZN  A 998 ( 3.5A)
ZN  A 998 ( 3.8A)
ZN  A 998 ( 3.6A)
0.17A 2ozrF-1fblA:
27.2
2ozrF-1fblA:
29.73
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3BA0_A_HAEA477_1
(MACROPHAGE
METALLOELASTASE)
1fbl FIBROBLAST
(INTERSTITIAL)
COLLAGENASE (MMP-1)

(Sus
scrofa)
3 / 3 HIS A 183
GLU A 219
HIS A 222
ZN  A 997 (-3.2A)
HTA  A 900 (-3.0A)
ZN  A 998 ( 3.8A)
0.54A 3ba0A-1fblA:
31.4
3ba0A-1fblA:
53.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3HY7_A_097A801_1
(A DISINTEGRIN AND
METALLOPROTEINASE
WITH THROMBOSPONDIN
MOTIFS 5)
1fbl FIBROBLAST
(INTERSTITIAL)
COLLAGENASE (MMP-1)

(Sus
scrofa)
5 / 9 LEU A 181
HIS A 218
GLU A 219
HIS A 222
HIS A 228
HTA  A 900 (-3.6A)
ZN  A 998 ( 3.5A)
HTA  A 900 (-3.0A)
ZN  A 998 ( 3.8A)
ZN  A 998 ( 3.6A)
0.43A 3hy7A-1fblA:
10.2
3hy7A-1fblA:
18.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3HY7_B_097B801_1
(A DISINTEGRIN AND
METALLOPROTEINASE
WITH THROMBOSPONDIN
MOTIFS 5)
1fbl FIBROBLAST
(INTERSTITIAL)
COLLAGENASE (MMP-1)

(Sus
scrofa)
5 / 9 LEU A 181
HIS A 218
GLU A 219
HIS A 222
HIS A 228
HTA  A 900 (-3.6A)
ZN  A 998 ( 3.5A)
HTA  A 900 (-3.0A)
ZN  A 998 ( 3.8A)
ZN  A 998 ( 3.6A)
0.44A 3hy7B-1fblA:
10.1
3hy7B-1fblA:
18.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KEC_A_HAEA272_1
(COLLAGENASE 3)
1fbl FIBROBLAST
(INTERSTITIAL)
COLLAGENASE (MMP-1)

(Sus
scrofa)
4 / 5 HIS A 218
GLU A 219
HIS A 222
HIS A 228
ZN  A 998 ( 3.5A)
HTA  A 900 (-3.0A)
ZN  A 998 ( 3.8A)
ZN  A 998 ( 3.6A)
0.41A 3kecA-1fblA:
27.6
3kecA-1fblA:
29.70
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3LIK_A_HAEA302_1
(MACROPHAGE
METALLOELASTASE)
1fbl FIBROBLAST
(INTERSTITIAL)
COLLAGENASE (MMP-1)

(Sus
scrofa)
5 / 5 HIS A 183
HIS A 218
GLU A 219
HIS A 222
HIS A 228
ZN  A 997 (-3.2A)
ZN  A 998 ( 3.5A)
HTA  A 900 (-3.0A)
ZN  A 998 ( 3.8A)
ZN  A 998 ( 3.6A)
0.47A 3likA-1fblA:
27.8
3likA-1fblA:
37.02
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3LIL_A_HAEA302_1
(MACROPHAGE
METALLOELASTASE)
1fbl FIBROBLAST
(INTERSTITIAL)
COLLAGENASE (MMP-1)

(Sus
scrofa)
4 / 4 HIS A 218
GLU A 219
HIS A 222
HIS A 228
ZN  A 998 ( 3.5A)
HTA  A 900 (-3.0A)
ZN  A 998 ( 3.8A)
ZN  A 998 ( 3.6A)
0.45A 3lilA-1fblA:
27.9
3lilA-1fblA:
37.02
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3LJG_A_HAEA301_1
(MACROPHAGE
METALLOELASTASE)
1fbl FIBROBLAST
(INTERSTITIAL)
COLLAGENASE (MMP-1)

(Sus
scrofa)
4 / 5 HIS A 218
GLU A 219
HIS A 222
HIS A 228
ZN  A 998 ( 3.5A)
HTA  A 900 (-3.0A)
ZN  A 998 ( 3.8A)
ZN  A 998 ( 3.6A)
0.45A 3ljgA-1fblA:
28.1
3ljgA-1fblA:
37.02
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3LKA_A_HAEA269_1
(MACROPHAGE
METALLOELASTASE)
1fbl FIBROBLAST
(INTERSTITIAL)
COLLAGENASE (MMP-1)

(Sus
scrofa)
5 / 5 HIS A 183
HIS A 218
GLU A 219
HIS A 222
HIS A 228
ZN  A 997 (-3.2A)
ZN  A 998 ( 3.5A)
HTA  A 900 (-3.0A)
ZN  A 998 ( 3.8A)
ZN  A 998 ( 3.6A)
0.47A 3lkaA-1fblA:
27.8
3lkaA-1fblA:
37.74
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4A7B_A_HAEA1273_1
(COLLAGENASE 3)
1fbl FIBROBLAST
(INTERSTITIAL)
COLLAGENASE (MMP-1)

(Sus
scrofa)
5 / 6 HIS A 183
HIS A 218
GLU A 219
HIS A 222
HIS A 228
ZN  A 997 (-3.2A)
ZN  A 998 ( 3.5A)
HTA  A 900 (-3.0A)
ZN  A 998 ( 3.8A)
ZN  A 998 ( 3.6A)
0.53A 4a7bA-1fblA:
27.8
4a7bA-1fblA:
34.38
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4A7B_B_HAEB1270_1
(COLLAGENASE 3)
1fbl FIBROBLAST
(INTERSTITIAL)
COLLAGENASE (MMP-1)

(Sus
scrofa)
4 / 5 HIS A 183
HIS A 218
GLU A 219
HIS A 222
ZN  A 997 (-3.2A)
ZN  A 998 ( 3.5A)
HTA  A 900 (-3.0A)
ZN  A 998 ( 3.8A)
0.40A 4a7bB-1fblA:
27.4
4a7bB-1fblA:
34.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ACA_B_DXCB1473_0
(TRANSLATION
ELONGATION FACTOR
SELB)
1fbl FIBROBLAST
(INTERSTITIAL)
COLLAGENASE (MMP-1)

(Sus
scrofa)
5 / 9 ASP A 194
ILE A 159
GLY A 193
GLY A 221
ARG A 214
CA  A 995 (-3.3A)
None
CA  A 995 ( 4.9A)
None
HTA  A 900 ( 4.9A)
1.27A 4acaB-1fblA:
undetectable
4acaC-1fblA:
undetectable
4acaB-1fblA:
23.22
4acaC-1fblA:
23.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ODO_B_FK5B203_2
(PEPTIDYL-PROLYL
CIS-TRANS ISOMERASE
SLYD)
1fbl FIBROBLAST
(INTERSTITIAL)
COLLAGENASE (MMP-1)

(Sus
scrofa)
3 / 3 ALA A 331
GLN A 431
GLY A 434
None
0.56A 4odoC-1fblA:
undetectable
4odoC-1fblA:
17.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4W5Q_A_IPHA903_0
(PROTEIN ARGONAUTE-2)
1fbl FIBROBLAST
(INTERSTITIAL)
COLLAGENASE (MMP-1)

(Sus
scrofa)
4 / 5 TYR A 348
LYS A 362
PRO A 361
LEU A 357
None
1.45A 4w5qA-1fblA:
3.1
4w5qA-1fblA:
16.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5G5G_A_ACTA1231_0
(PUTATIVE XANTHINE
DEHYDROGENASE YAGR
MOLYBDENUM-BINDING
SU SUBUNIT
PUTATIVE XANTHINE
DEHYDROGENASE YAGT
IRON-SULFUR-BINDING
SUBUNIT)
1fbl FIBROBLAST
(INTERSTITIAL)
COLLAGENASE (MMP-1)

(Sus
scrofa)
3 / 3 ARG A 300
THR A 243
ASP A 245
None
0.95A 5g5gA-1fblA:
0.0
5g5gB-1fblA:
0.0
5g5gA-1fblA:
20.67
5g5gB-1fblA:
23.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5LRB_A_ACRA1003_1
(ALPHA-1,4 GLUCAN
PHOSPHORYLASE)
1fbl FIBROBLAST
(INTERSTITIAL)
COLLAGENASE (MMP-1)

(Sus
scrofa)
4 / 6 GLU A 418
THR A 409
TYR A 411
PHE A 419
None
1.04A 5lrbA-1fblA:
undetectable
5lrbA-1fblA:
17.82
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5N5J_A_HAEA306_1
(MACROPHAGE
METALLOELASTASE)
1fbl FIBROBLAST
(INTERSTITIAL)
COLLAGENASE (MMP-1)

(Sus
scrofa)
4 / 4 HIS A 218
GLU A 219
HIS A 222
HIS A 228
ZN  A 998 ( 3.5A)
HTA  A 900 (-3.0A)
ZN  A 998 ( 3.8A)
ZN  A 998 ( 3.6A)
0.43A 5n5jA-1fblA:
27.9
5n5jA-1fblA:
37.74
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5N5K_A_HAEA306_1
(MACROPHAGE
METALLOELASTASE)
1fbl FIBROBLAST
(INTERSTITIAL)
COLLAGENASE (MMP-1)

(Sus
scrofa)
4 / 5 HIS A 218
GLU A 219
HIS A 222
HIS A 228
ZN  A 998 ( 3.5A)
HTA  A 900 (-3.0A)
ZN  A 998 ( 3.8A)
ZN  A 998 ( 3.6A)
0.46A 5n5kA-1fblA:
27.4
5n5kA-1fblA:
36.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6C2M_D_SUED1202_1
(NS3 PROTEASE)
1fbl FIBROBLAST
(INTERSTITIAL)
COLLAGENASE (MMP-1)

(Sus
scrofa)
4 / 9 PHE A 197
VAL A 215
HIS A 218
ASP A 209
None
HTA  A 900 ( 4.0A)
ZN  A 998 ( 3.5A)
None
0.92A 6c2mD-1fblA:
0.0
6c2mD-1fblA:
12.50