SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '1fbw'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1A4L_C_DCFC1353_2
(ADENOSINE DEAMINASE)		 1fbw ENDO-1,4-BETA-GLUCAN
ASE F
([Clostridium]
cellulolyticum) 		4 / 5 LEU A 332
SER A 270
LEU A 296
GLY A 264
 None
 0.84A 1a4lC-1fbwA:
undetectable		 1a4lC-1fbwA:
19.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1KXH_A_ACRA598_2
(ALPHA-AMYLASE)		 1fbw ENDO-1,4-BETA-GLUCAN
ASE F
([Clostridium]
cellulolyticum) 		3 / 3 TRP A 362
TYR A 393
LEU A 295
 None
 0.93A 1kxhA-1fbwA:
0.4		 1kxhA-1fbwA:
22.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1L5Q_B_CFFB1864_1
(GLYCOGEN
PHOSPHORYLASE, LIVER
FORM)		 1fbw ENDO-1,4-BETA-GLUCAN
ASE F
([Clostridium]
cellulolyticum) 		3 / 3 TRP A 411
HIS A 320
MET A 414
 GLC  A3101 ( 4.2A)
None
None
 1.35A 1l5qB-1fbwA:
0.0		 1l5qB-1fbwA:
20.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1N2X_A_SAMA401_1
(S-ADENOSYL-METHYLTRA
NSFERASE MRAW)		 1fbw ENDO-1,4-BETA-GLUCAN
ASE F
([Clostridium]
cellulolyticum) 		4 / 4 HIS A  67
ASP A  78
SER A 254
ASP A  73
 None
 1.50A 1n2xA-1fbwA:
undetectable		 1n2xA-1fbwA:
17.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1N2X_B_SAMB402_0
(S-ADENOSYL-METHYLTRA
NSFERASE MRAW)		 1fbw ENDO-1,4-BETA-GLUCAN
ASE F
([Clostridium]
cellulolyticum) 		5 / 12 GLY A 322
GLY A 372
ASP A 230
GLY A 413
ASN A 503
 None
 0.95A 1n2xB-1fbwA:
undetectable		 1n2xB-1fbwA:
17.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1TT0_A_ACTA4901_0
(PYRANOSE OXIDASE)		 1fbw ENDO-1,4-BETA-GLUCAN
ASE F
([Clostridium]
cellulolyticum) 		4 / 6 GLN A 415
PHE A 321
HIS A 320
ASN A 409
 None
 1.08A 1tt0A-1fbwA:
0.0		 1tt0A-1fbwA:
21.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1TT0_B_ACTB3901_0
(PYRANOSE OXIDASE)		 1fbw ENDO-1,4-BETA-GLUCAN
ASE F
([Clostridium]
cellulolyticum) 		4 / 6 GLN A 415
PHE A 321
HIS A 320
ASN A 409
 None
 1.08A 1tt0B-1fbwA:
0.0		 1tt0B-1fbwA:
21.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1TT0_C_ACTC6901_0
(PYRANOSE OXIDASE)		 1fbw ENDO-1,4-BETA-GLUCAN
ASE F
([Clostridium]
cellulolyticum) 		4 / 6 GLN A 415
PHE A 321
HIS A 320
ASN A 409
 None
 1.08A 1tt0C-1fbwA:
0.0		 1tt0C-1fbwA:
21.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1TT0_D_ACTD5901_0
(PYRANOSE OXIDASE)		 1fbw ENDO-1,4-BETA-GLUCAN
ASE F
([Clostridium]
cellulolyticum) 		4 / 6 GLN A 415
PHE A 321
HIS A 320
ASN A 409
 None
 1.09A 1tt0D-1fbwA:
0.0		 1tt0D-1fbwA:
21.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1VE9_A_BEZA352_0
(D-AMINO ACID OXIDASE)		 1fbw ENDO-1,4-BETA-GLUCAN
ASE F
([Clostridium]
cellulolyticum) 		4 / 5 TYR A 382
TYR A 275
ILE A 314
GLY A 380
 None
GLC  A3095 (-4.7A)
GLC  A3095 ( 4.6A)
None
 1.34A 1ve9A-1fbwA:
undetectable		 1ve9A-1fbwA:
20.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1Y7I_A_SALA501_1
(SALICYLIC
ACID-BINDING PROTEIN
2)		 1fbw ENDO-1,4-BETA-GLUCAN
ASE F
([Clostridium]
cellulolyticum) 		5 / 9 ALA A 329
SER A 352
LEU A 353
TYR A 360
LEU A 425
 None
 1.34A 1y7iA-1fbwA:
undetectable		 1y7iA-1fbwA:
15.98
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1Y7I_B_SALB503_1
(SALICYLIC
ACID-BINDING PROTEIN
2)		 1fbw ENDO-1,4-BETA-GLUCAN
ASE F
([Clostridium]
cellulolyticum) 		5 / 10 ALA A 329
SER A 352
LEU A 353
TYR A 360
LEU A 425
 None
 1.29A 1y7iB-1fbwA:
undetectable		 1y7iB-1fbwA:
15.98
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2A3A_A_TEPA1435_1
(CHITINASE)		 1fbw ENDO-1,4-BETA-GLUCAN
ASE F
([Clostridium]
cellulolyticum) 		3 / 3 TRP A 241
GLU A 424
TYR A 507
 None
 1.22A 2a3aA-1fbwA:
undetectable		 2a3aA-1fbwA:
22.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2AOX_A_THAA400_1
(HISTAMINE
N-METHYLTRANSFERASE)		 1fbw ENDO-1,4-BETA-GLUCAN
ASE F
([Clostridium]
cellulolyticum) 		4 / 8 PHE A 577
PHE A 550
TYR A  48
TYR A 162
 None
 1.30A 2aoxA-1fbwA:
undetectable		 2aoxA-1fbwA:
18.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2C49_B_ADNB1301_1
(SUGAR KINASE MJ0406)		 1fbw ENDO-1,4-BETA-GLUCAN
ASE F
([Clostridium]
cellulolyticum) 		4 / 7 ALA A 166
ASP A 169
GLY A 165
ASN A 160
 None
 0.75A 2c49B-1fbwA:
undetectable		 2c49B-1fbwA:
18.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2DU8_G_BEZG2352_0
(D-AMINO-ACID OXIDASE)		 1fbw ENDO-1,4-BETA-GLUCAN
ASE F
([Clostridium]
cellulolyticum) 		4 / 5 TYR A 300
TYR A 269
ILE A 136
GLY A 151
 None
 1.37A 2du8G-1fbwA:
undetectable		 2du8G-1fbwA:
17.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2DU8_G_BEZG2352_0
(D-AMINO-ACID OXIDASE)		 1fbw ENDO-1,4-BETA-GLUCAN
ASE F
([Clostridium]
cellulolyticum) 		4 / 5 TYR A 382
TYR A 275
ILE A 314
GLY A 380
 None
GLC  A3095 (-4.7A)
GLC  A3095 ( 4.6A)
None
 1.35A 2du8G-1fbwA:
undetectable		 2du8G-1fbwA:
17.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2DU8_J_BEZJ3352_0
(D-AMINO-ACID OXIDASE)		 1fbw ENDO-1,4-BETA-GLUCAN
ASE F
([Clostridium]
cellulolyticum) 		4 / 5 TYR A 382
TYR A 275
ILE A 314
GLY A 380
 None
GLC  A3095 (-4.7A)
GLC  A3095 ( 4.6A)
None
 1.31A 2du8J-1fbwA:
undetectable		 2du8J-1fbwA:
17.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2HDN_F_TACF3888_1
(ELONGATION FACTOR
EF-TU)		 1fbw ENDO-1,4-BETA-GLUCAN
ASE F
([Clostridium]
cellulolyticum) 		4 / 7 SER A 187
ASP A 405
VAL A  43
LEU A 597
 CA  A2000 ( 4.7A)
CA  A2000 (-3.6A)
None
None
 0.96A 2hdnE-1fbwA:
0.0
2hdnF-1fbwA:
undetectable
2hdnH-1fbwA:
undetectable		 2hdnE-1fbwA:
4.95
2hdnF-1fbwA:
20.13
2hdnH-1fbwA:
20.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2HDN_H_TACH4888_1
(ELONGATION FACTOR
EF-TU)		 1fbw ENDO-1,4-BETA-GLUCAN
ASE F
([Clostridium]
cellulolyticum) 		4 / 7 VAL A  43
LEU A 597
SER A 187
ASP A 405
 None
None
CA  A2000 ( 4.7A)
CA  A2000 (-3.6A)
 0.98A 2hdnF-1fbwA:
undetectable
2hdnG-1fbwA:
0.0
2hdnH-1fbwA:
undetectable		 2hdnF-1fbwA:
20.13
2hdnG-1fbwA:
4.95
2hdnH-1fbwA:
20.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2NXE_A_SAMA302_1
(RIBOSOMAL PROTEIN
L11
METHYLTRANSFERASE)		 1fbw ENDO-1,4-BETA-GLUCAN
ASE F
([Clostridium]
cellulolyticum) 		3 / 3 THR A 334
ASP A 243
SER A 254
 None
 0.81A 2nxeA-1fbwA:
undetectable		 2nxeA-1fbwA:
17.01
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2NXE_B_SAMB303_1
(RIBOSOMAL PROTEIN
L11
METHYLTRANSFERASE)		 1fbw ENDO-1,4-BETA-GLUCAN
ASE F
([Clostridium]
cellulolyticum) 		3 / 3 THR A 334
ASP A 243
SER A 254
 None
 0.82A 2nxeB-1fbwA:
undetectable		 2nxeB-1fbwA:
17.01
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2XDC_A_DVAA8_0
(GRAMICIDIN A)		 1fbw ENDO-1,4-BETA-GLUCAN
ASE F
([Clostridium]
cellulolyticum) 		3 / 3 VAL A 236
TRP A 241
TRP A  62
 None
 1.31A 2xdcA-1fbwA:
undetectable
2xdcB-1fbwA:
undetectable		 2xdcA-1fbwA:
5.22
2xdcB-1fbwA:
5.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2XDC_B_DVAB8_0
(GRAMICIDIN A)		 1fbw ENDO-1,4-BETA-GLUCAN
ASE F
([Clostridium]
cellulolyticum) 		3 / 3 TRP A  62
VAL A 236
TRP A 241
 None
 1.32A 2xdcA-1fbwA:
undetectable
2xdcB-1fbwA:
undetectable		 2xdcA-1fbwA:
5.22
2xdcB-1fbwA:
5.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2Y5M_A_DVAA8_0
(VAL-GRAMICIDIN A)		 1fbw ENDO-1,4-BETA-GLUCAN
ASE F
([Clostridium]
cellulolyticum) 		3 / 3 VAL A 236
TRP A 241
TRP A  62
 None
 1.29A 2y5mA-1fbwA:
undetectable
2y5mB-1fbwA:
undetectable		 2y5mA-1fbwA:
5.22
2y5mB-1fbwA:
5.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2Y6N_A_DVAA8_0
(VAL-GRAMICIDIN A)		 1fbw ENDO-1,4-BETA-GLUCAN
ASE F
([Clostridium]
cellulolyticum) 		3 / 3 VAL A 236
TRP A 241
TRP A  62
 None
 1.30A 2y6nA-1fbwA:
undetectable
2y6nB-1fbwA:
undetectable		 2y6nA-1fbwA:
5.22
2y6nB-1fbwA:
5.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2Y6N_B_DVAB8_0
(VAL-GRAMICIDIN A)		 1fbw ENDO-1,4-BETA-GLUCAN
ASE F
([Clostridium]
cellulolyticum) 		3 / 3 TRP A  62
VAL A 236
TRP A 241
 None
 1.31A 2y6nA-1fbwA:
undetectable
2y6nB-1fbwA:
undetectable		 2y6nA-1fbwA:
5.22
2y6nB-1fbwA:
5.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2YA7_B_ZMRB1776_2
(NEURAMINIDASE A)		 1fbw ENDO-1,4-BETA-GLUCAN
ASE F
([Clostridium]
cellulolyticum) 		4 / 6 ARG A 133
ASP A 134
ILE A 313
LEU A 149
 None
 1.00A 2ya7B-1fbwA:
undetectable		 2ya7B-1fbwA:
22.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ZT7_A_GLYA1300_0
(GLYCYL-TRNA
SYNTHETASE)		 1fbw ENDO-1,4-BETA-GLUCAN
ASE F
([Clostridium]
cellulolyticum) 		4 / 7 ARG A 421
TYR A  59
GLU A 615
SER A 500
 None
 1.18A 2zt7A-1fbwA:
undetectable		 2zt7A-1fbwA:
20.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ARU_A_PNXA607_1
(CHITINASE A)		 1fbw ENDO-1,4-BETA-GLUCAN
ASE F
([Clostridium]
cellulolyticum) 		4 / 8 GLY A  76
THR A  75
GLU A  64
GLY A  68
 None
 0.69A 3aruA-1fbwA:
undetectable		 3aruA-1fbwA:
22.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3D91_A_REMA350_2
(RENIN)		 1fbw ENDO-1,4-BETA-GLUCAN
ASE F
([Clostridium]
cellulolyticum) 		4 / 5 TYR A   9
ALA A 509
ALA A 619
MET A  66
 None
 1.23A 3d91A-1fbwA:
undetectable		 3d91A-1fbwA:
20.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3HUO_A_PNNA303_0
(CTX-M-9
EXTENDED-SPECTRUM
BETA-LACTAMASE)		 1fbw ENDO-1,4-BETA-GLUCAN
ASE F
([Clostridium]
cellulolyticum) 		4 / 4 GLN A 356
GLN A 324
GLY A 322
HIS A 320
 None
 1.41A 3huoA-1fbwA:
0.0		 3huoA-1fbwA:
18.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3LSK_B_ACTB901_0
(PYRANOSE 2-OXIDASE)		 1fbw ENDO-1,4-BETA-GLUCAN
ASE F
([Clostridium]
cellulolyticum) 		4 / 6 GLN A 415
PHE A 321
HIS A 320
ASN A 409
 None
 1.09A 3lskB-1fbwA:
0.0		 3lskB-1fbwA:
21.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3LSK_D_ACTD901_0
(PYRANOSE 2-OXIDASE)		 1fbw ENDO-1,4-BETA-GLUCAN
ASE F
([Clostridium]
cellulolyticum) 		4 / 6 GLN A 415
PHE A 321
HIS A 320
ASN A 409
 None
 1.05A 3lskD-1fbwA:
undetectable		 3lskD-1fbwA:
21.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3MDT_B_VORB506_1
(CHOLESTEROL
24-HYDROXYLASE)		 1fbw ENDO-1,4-BETA-GLUCAN
ASE F
([Clostridium]
cellulolyticum) 		6 / 11 LEU A 501
SER A 500
ILE A 445
ALA A 423
ALA A 509
ALA A 442
 None
 1.33A 3mdtB-1fbwA:
0.0		 3mdtB-1fbwA:
21.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3N62_B_ACTB860_0
(NITRIC OXIDE
SYNTHASE)		 1fbw ENDO-1,4-BETA-GLUCAN
ASE F
([Clostridium]
cellulolyticum) 		3 / 3 GLY A 496
TRP A 417
VAL A 416
 None
 0.54A 3n62B-1fbwA:
0.0		 3n62B-1fbwA:
21.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3N65_B_ACTB860_0
(NITRIC OXIDE
SYNTHASE)		 1fbw ENDO-1,4-BETA-GLUCAN
ASE F
([Clostridium]
cellulolyticum) 		3 / 3 GLY A 496
TRP A 417
VAL A 416
 None
 0.52A 3n65B-1fbwA:
0.0		 3n65B-1fbwA:
21.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3N66_B_ACTB860_0
(NITRIC OXIDE
SYNTHASE)		 1fbw ENDO-1,4-BETA-GLUCAN
ASE F
([Clostridium]
cellulolyticum) 		3 / 3 GLY A 496
TRP A 417
VAL A 416
 None
 0.54A 3n66B-1fbwA:
0.0		 3n66B-1fbwA:
21.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ROX_A_TEPA266_1
(APOLIPOPROTEIN
A-I-BINDING PROTEIN)		 1fbw ENDO-1,4-BETA-GLUCAN
ASE F
([Clostridium]
cellulolyticum) 		4 / 8 ALA A 619
VAL A 622
LEU A 626
LEU A 505
 None
 0.73A 3roxA-1fbwA:
undetectable		 3roxA-1fbwA:
16.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3TM4_A_SAMA401_0
(TRNA (GUANINE
N2-)-METHYLTRANSFERA
SE TRM14)		 1fbw ENDO-1,4-BETA-GLUCAN
ASE F
([Clostridium]
cellulolyticum) 		5 / 12 HIS A  67
LEU A  63
GLY A 621
TYR A   9
ALA A 502
 None
 1.34A 3tm4A-1fbwA:
undetectable		 3tm4A-1fbwA:
19.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3TWP_D_SALD404_1
(ANTHRANILATE
PHOSPHORIBOSYLTRANSF
ERASE)		 1fbw ENDO-1,4-BETA-GLUCAN
ASE F
([Clostridium]
cellulolyticum) 		4 / 5 ASN A 227
ALA A 228
PRO A 229
ALA A 233
 None
GLC  A3098 ( 4.0A)
None
None
 1.24A 3twpD-1fbwA:
1.6		 3twpD-1fbwA:
20.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4FFW_B_715B801_2
(DIPEPTIDYL PEPTIDASE
4)		 1fbw ENDO-1,4-BETA-GLUCAN
ASE F
([Clostridium]
cellulolyticum) 		3 / 3 ARG A 268
TYR A 393
ASN A 319
 None
 0.79A 4ffwB-1fbwA:
0.0		 4ffwB-1fbwA:
20.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4FFW_B_715B801_2
(DIPEPTIDYL PEPTIDASE
4)		 1fbw ENDO-1,4-BETA-GLUCAN
ASE F
([Clostridium]
cellulolyticum) 		3 / 3 ARG A 277
TYR A 294
ASN A 319
 None
 0.89A 4ffwB-1fbwA:
0.0		 4ffwB-1fbwA:
20.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4IQQ_D_D16D402_1
(THYMIDYLATE SYNTHASE)		 1fbw ENDO-1,4-BETA-GLUCAN
ASE F
([Clostridium]
cellulolyticum) 		5 / 8 TYR A 162
ILE A 177
ASP A 169
GLY A 170
PHE A 164
 None
 1.49A 4iqqD-1fbwA:
undetectable		 4iqqD-1fbwA:
19.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4L1A_A_AB1A101_1
(MDR769 HIV-1
PROTEASE)		 1fbw ENDO-1,4-BETA-GLUCAN
ASE F
([Clostridium]
cellulolyticum) 		5 / 11 GLY A 165
ALA A 166
ILE A 306
THR A  91
PRO A  90
 None
 1.09A 4l1aA-1fbwA:
undetectable		 4l1aA-1fbwA:
9.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4UHX_A_LZUA3008_1
(ALDEHYDE OXIDASE)		 1fbw ENDO-1,4-BETA-GLUCAN
ASE F
([Clostridium]
cellulolyticum) 		4 / 8 HIS A 320
SER A 418
TRP A 441
TRP A 444
 None
 1.22A 4uhxA-1fbwA:
undetectable		 4uhxA-1fbwA:
18.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4YDQ_A_HFGA802_0
(PROLINE--TRNA LIGASE)		 1fbw ENDO-1,4-BETA-GLUCAN
ASE F
([Clostridium]
cellulolyticum) 		5 / 12 LEU A 357
VAL A 422
PRO A 326
ARG A 421
SER A 270
 None
 1.37A 4ydqA-1fbwA:
undetectable		 4ydqA-1fbwA:
21.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5C6P_A_4YHA601_1
(PROTEIN C)		 1fbw ENDO-1,4-BETA-GLUCAN
ASE F
([Clostridium]
cellulolyticum) 		4 / 6 ALA A 404
GLN A 553
ASP A 117
PRO A 118
 None
 1.03A 5c6pA-1fbwA:
0.0		 5c6pA-1fbwA:
21.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5FUQ_A_ACTA1278_0
(NAD(P)H
DEHYDROGENASE
[QUINONE] 1)		 1fbw ENDO-1,4-BETA-GLUCAN
ASE F
([Clostridium]
cellulolyticum) 		4 / 5 HIS A 318
SER A 317
ILE A 314
TYR A 275
 None
None
GLC  A3095 ( 4.6A)
GLC  A3095 (-4.7A)
 1.37A 5fuqA-1fbwA:
0.0
5fuqB-1fbwA:
0.0		 5fuqA-1fbwA:
18.84
5fuqB-1fbwA:
18.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5HBS_A_RTLA201_1
(RETINOL-BINDING
PROTEIN 1)		 1fbw ENDO-1,4-BETA-GLUCAN
ASE F
([Clostridium]
cellulolyticum) 		4 / 8 LEU A 149
THR A 226
TYR A 299
GLN A 194
 None
GLC  A3097 ( 3.0A)
GLC  A3097 ( 4.1A)
None
 1.19A 5hbsA-1fbwA:
0.0		 5hbsA-1fbwA:
10.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5IKR_B_ID8B602_2
(PROSTAGLANDIN G/H
SYNTHASE 2)		 1fbw ENDO-1,4-BETA-GLUCAN
ASE F
([Clostridium]
cellulolyticum) 		3 / 3 SER A  37
LEU A  88
MET A  57
 None
 0.83A 5ikrB-1fbwA:
0.0		 5ikrB-1fbwA:
19.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5L1F_C_6ZPC902_1
(GLUTAMATE RECEPTOR 2)		 1fbw ENDO-1,4-BETA-GLUCAN
ASE F
([Clostridium]
cellulolyticum) 		4 / 7 ASP A 134
PRO A 135
TYR A 289
SER A 297
 None
 1.24A 5l1fC-1fbwA:
undetectable		 5l1fC-1fbwA:
21.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5NOO_D_D16D402_1
(THYMIDYLATE SYNTHASE)		 1fbw ENDO-1,4-BETA-GLUCAN
ASE F
([Clostridium]
cellulolyticum) 		5 / 8 TYR A 162
ILE A 177
ASP A 169
GLY A 170
PHE A 164
 None
 1.46A 5nooD-1fbwA:
undetectable		 5nooD-1fbwA:
19.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ODC_G_ACTG704_0
(HETERODISULFIDE
REDUCTASE, SUBUNIT A)		 1fbw ENDO-1,4-BETA-GLUCAN
ASE F
([Clostridium]
cellulolyticum) 		4 / 5 PRO A 326
ALA A 328
GLN A 420
GLN A 237
 None
 1.47A 5odcA-1fbwA:
undetectable
5odcG-1fbwA:
undetectable		 5odcA-1fbwA:
20.96
5odcG-1fbwA:
20.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VUO_B_ACTB804_0
(NITRIC OXIDE
SYNTHASE, BRAIN)		 1fbw ENDO-1,4-BETA-GLUCAN
ASE F
([Clostridium]
cellulolyticum) 		3 / 3 GLY A 496
TRP A 417
VAL A 416
 None
 0.53A 5vuoB-1fbwA:
0.0		 5vuoB-1fbwA:
21.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5X2T_I_PEMI202_1
(HEMOGLOBIN SUBUNIT
ALPHA
HEMOGLOBIN SUBUNIT
BETA)		 1fbw ENDO-1,4-BETA-GLUCAN
ASE F
([Clostridium]
cellulolyticum) 		4 / 8 PRO A 193
ALA A  45
THR A 188
THR A 191
 None
GLC  A3100 ( 3.9A)
None
None
 1.02A 5x2tI-1fbwA:
undetectable
5x2tJ-1fbwA:
undetectable
5x2tK-1fbwA:
undetectable
5x2tL-1fbwA:
undetectable		 5x2tI-1fbwA:
11.98
5x2tJ-1fbwA:
12.70
5x2tK-1fbwA:
11.98
5x2tL-1fbwA:
12.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6FGC_A_ACTA813_0
(GEPHYRIN)		 1fbw ENDO-1,4-BETA-GLUCAN
ASE F
([Clostridium]
cellulolyticum) 		3 / 3 THR A 239
ALA A 260
LYS A 262
 None
 0.52A 6fgcA-1fbwA:
0.0		 6fgcA-1fbwA:
21.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6FGD_A_ACTA817_0
(GEPHYRIN)		 1fbw ENDO-1,4-BETA-GLUCAN
ASE F
([Clostridium]
cellulolyticum) 		3 / 3 THR A 239
ALA A 260
LYS A 262
 None
 0.48A 6fgdA-1fbwA:
undetectable		 6fgdA-1fbwA:
21.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6FGD_A_ACTA821_0
(GEPHYRIN)		 1fbw ENDO-1,4-BETA-GLUCAN
ASE F
([Clostridium]
cellulolyticum) 		3 / 3 ARG A 133
PHE A 276
GLY A 288
 None
 0.67A 6fgdA-1fbwA:
0.0		 6fgdA-1fbwA:
21.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6JNH_A_ASCA202_0
(PHOSPHOPANTETHEINE
ADENYLYLTRANSFERASE)		 1fbw ENDO-1,4-BETA-GLUCAN
ASE F
([Clostridium]
cellulolyticum) 		3 / 3 ASN A 376
PRO A 282
GLN A 284
 None
 0.70A 6jnhA-1fbwA:
undetectable		 6jnhA-1fbwA:
13.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6JOG_A_ASCA202_0
(PHOSPHOPANTETHEINE
ADENYLYLTRANSFERASE)		 1fbw ENDO-1,4-BETA-GLUCAN
ASE F
([Clostridium]
cellulolyticum) 		3 / 3 ASN A 376
PRO A 282
GLN A 284
 None
 0.72A 6jogA-1fbwA:
undetectable		 6jogA-1fbwA:
13.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6QGB_E_BEZE701_0
(MONO(2-HYDROXYETHYL)
TEREPHTHALATE
HYDROLASE)		 1fbw ENDO-1,4-BETA-GLUCAN
ASE F
([Clostridium]
cellulolyticum) 		5 / 11 GLY A 258
ALA A 238
PHE A 338
ALA A 242
PHE A  77
 None
 1.19A 6qgbE-1fbwA:
undetectable		 6qgbE-1fbwA:
21.68