SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '1fc9'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site

Query pattern: Residues from known binding site for annotated drug that match the hit pattern


(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID
Hit
Macromolecule
Res.
Matches
Interface HETATM RMSD Dali
Z-score
Seq.
Identity (%)
View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1CLA_A_CLMA221_0
(TYPE III
CHLORAMPHENICOL
ACETYLTRANSFERASE)
1fc9 PHOTOSYSTEM II D1
PROTEASE

(Tetradesmus
obliquus)
5 / 10 ALA A 195
PHE A 395
ALA A 193
LEU A 219
VAL A 215
None
1.28A 1claA-1fc9A:
0.0
1claA-1fc9A:
18.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1FAP_A_RAPA108_2
(FK506-BINDING
PROTEIN
FRAP)
1fc9 PHOTOSYSTEM II D1
PROTEASE

(Tetradesmus
obliquus)
4 / 8 LEU A 133
PHE A 101
GLY A 103
TRP A 106
None
0.87A 1fapB-1fc9A:
0.4
1fapB-1fc9A:
12.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GTF_T_TRPT81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN
(TRAP))
1fc9 PHOTOSYSTEM II D1
PROTEASE

(Tetradesmus
obliquus)
5 / 10 GLY A 431
ALA A 378
THR A 370
THR A 394
SER A 374
None
1.33A 1gtfT-1fc9A:
0.0
1gtfU-1fc9A:
0.0
1gtfT-1fc9A:
12.11
1gtfU-1fc9A:
12.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GTN_L_TRPL81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN)
1fc9 PHOTOSYSTEM II D1
PROTEASE

(Tetradesmus
obliquus)
5 / 9 GLY A 431
ALA A 378
THR A 370
THR A 394
SER A 374
None
1.33A 1gtnL-1fc9A:
0.0
1gtnM-1fc9A:
0.2
1gtnL-1fc9A:
12.11
1gtnM-1fc9A:
12.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GTN_O_TRPO81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN)
1fc9 PHOTOSYSTEM II D1
PROTEASE

(Tetradesmus
obliquus)
5 / 10 GLY A 431
ALA A 378
THR A 370
THR A 394
SER A 374
None
1.35A 1gtnO-1fc9A:
0.0
1gtnP-1fc9A:
undetectable
1gtnO-1fc9A:
12.11
1gtnP-1fc9A:
12.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GTN_Q_TRPQ81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN)
1fc9 PHOTOSYSTEM II D1
PROTEASE

(Tetradesmus
obliquus)
5 / 9 GLY A 431
ALA A 378
THR A 370
THR A 394
SER A 374
None
1.33A 1gtnQ-1fc9A:
0.0
1gtnR-1fc9A:
undetectable
1gtnQ-1fc9A:
12.11
1gtnR-1fc9A:
12.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GTN_R_TRPR81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN)
1fc9 PHOTOSYSTEM II D1
PROTEASE

(Tetradesmus
obliquus)
5 / 9 GLY A 431
ALA A 378
THR A 370
THR A 394
SER A 374
None
1.36A 1gtnR-1fc9A:
0.0
1gtnS-1fc9A:
0.0
1gtnR-1fc9A:
12.11
1gtnS-1fc9A:
12.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GTN_S_TRPS81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN)
1fc9 PHOTOSYSTEM II D1
PROTEASE

(Tetradesmus
obliquus)
5 / 9 GLY A 431
ALA A 378
THR A 370
THR A 394
SER A 374
None
1.40A 1gtnS-1fc9A:
0.0
1gtnT-1fc9A:
0.0
1gtnS-1fc9A:
12.11
1gtnT-1fc9A:
12.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1MZ9_D_VDYD1001_2
(CARTILAGE OLIGOMERIC
MATRIX PROTEIN)
1fc9 PHOTOSYSTEM II D1
PROTEASE

(Tetradesmus
obliquus)
3 / 3 LEU A 212
VAL A 215
LEU A 219
None
0.49A 1mz9B-1fc9A:
undetectable
1mz9B-1fc9A:
8.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1R9O_A_FLPA501_1
(CYTOCHROME P450 2C9)
1fc9 PHOTOSYSTEM II D1
PROTEASE

(Tetradesmus
obliquus)
5 / 12 VAL A 280
ILE A 356
LEU A 330
ALA A 296
LEU A 282
None
0.99A 1r9oA-1fc9A:
0.0
1r9oA-1fc9A:
22.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1T7J_A_478A200_1
(POL POLYPROTEIN)
1fc9 PHOTOSYSTEM II D1
PROTEASE

(Tetradesmus
obliquus)
5 / 11 LEU A 388
GLY A 391
ASP A 311
VAL A 309
VAL A 363
None
0.74A 1t7jA-1fc9A:
undetectable
1t7jA-1fc9A:
14.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1UTD_Q_TRPQ81_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)
1fc9 PHOTOSYSTEM II D1
PROTEASE

(Tetradesmus
obliquus)
5 / 10 GLY A 431
ALA A 378
THR A 370
THR A 394
SER A 374
None
1.36A 1utdQ-1fc9A:
undetectable
1utdR-1fc9A:
undetectable
1utdQ-1fc9A:
12.11
1utdR-1fc9A:
12.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1UTD_R_TRPR81_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)
1fc9 PHOTOSYSTEM II D1
PROTEASE

(Tetradesmus
obliquus)
5 / 10 GLY A 431
ALA A 378
THR A 370
THR A 394
SER A 374
None
1.33A 1utdR-1fc9A:
undetectable
1utdS-1fc9A:
0.0
1utdR-1fc9A:
12.11
1utdS-1fc9A:
12.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1VM1_A_TAZA504_1
(BETA-LACTAMASE SHV-1)
1fc9 PHOTOSYSTEM II D1
PROTEASE

(Tetradesmus
obliquus)
3 / 3 ASP A 127
TYR A 126
GLU A  81
None
0.83A 1vm1A-1fc9A:
0.0
1vm1A-1fc9A:
25.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2RCT_A_RTLA140_0
(RETINOL-BINDING
PROTEIN II, CELLULAR)
1fc9 PHOTOSYSTEM II D1
PROTEASE

(Tetradesmus
obliquus)
5 / 12 PHE A 297
MET A 329
ALA A 293
VAL A 366
LEU A 377
None
1.10A 2rctA-1fc9A:
0.0
2rctA-1fc9A:
16.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2YVL_B_SAMB602_0
(HYPOTHETICAL PROTEIN)
1fc9 PHOTOSYSTEM II D1
PROTEASE

(Tetradesmus
obliquus)
5 / 12 GLY A 409
GLY A 411
ALA A  88
ALA A 150
ASP A 408
None
1.13A 2yvlB-1fc9A:
undetectable
2yvlB-1fc9A:
21.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2YY8_B_SAMB500_0
(UPF0106 PROTEIN
PH0461)
1fc9 PHOTOSYSTEM II D1
PROTEASE

(Tetradesmus
obliquus)
5 / 11 LEU A 165
VAL A 163
GLY A 162
VAL A 250
ILE A 167
None
1.18A 2yy8A-1fc9A:
undetectable
2yy8B-1fc9A:
undetectable
2yy8A-1fc9A:
18.21
2yy8B-1fc9A:
18.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3DCM_X_SAMX5452_0
(UNCHARACTERIZED
PROTEIN TM_1570)
1fc9 PHOTOSYSTEM II D1
PROTEASE

(Tetradesmus
obliquus)
5 / 11 THR A 394
GLY A 398
ILE A 312
LEU A 377
ALA A 378
None
0.93A 3dcmX-1fc9A:
undetectable
3dcmX-1fc9A:
17.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3DEU_B_SALB306_1
(TRANSCRIPTIONAL
REGULATOR SLYA)
1fc9 PHOTOSYSTEM II D1
PROTEASE

(Tetradesmus
obliquus)
4 / 6 THR A 289
ILE A 312
SER A 374
LEU A 377
None
0.89A 3deuB-1fc9A:
undetectable
3deuB-1fc9A:
16.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3EKP_B_478B200_1
(PROTEASE)
1fc9 PHOTOSYSTEM II D1
PROTEASE

(Tetradesmus
obliquus)
5 / 8 GLY A 379
ALA A 378
GLY A 431
ILE A 430
ILE A 389
None
1.22A 3ekpA-1fc9A:
undetectable
3ekpA-1fc9A:
13.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3EM4_A_DR7A100_1
(PROTEASE)
1fc9 PHOTOSYSTEM II D1
PROTEASE

(Tetradesmus
obliquus)
6 / 11 ARG A 281
GLY A 323
ALA A 373
ILE A 427
GLY A 379
LEU A 381
None
1.45A 3em4A-1fc9A:
undetectable
3em4A-1fc9A:
12.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3N23_C_OBNC1_1
(SODIUM/POTASSIUM-TRA
NSPORTING ATPASE
SUBUNIT ALPHA-1)
1fc9 PHOTOSYSTEM II D1
PROTEASE

(Tetradesmus
obliquus)
5 / 11 ASP A 138
LEU A 136
VAL A  92
ALA A  91
THR A 141
None
1.15A 3n23C-1fc9A:
undetectable
3n23C-1fc9A:
17.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3OXW_B_017B200_2
(HIV-1 PROTEASE)
1fc9 PHOTOSYSTEM II D1
PROTEASE

(Tetradesmus
obliquus)
5 / 10 LEU A 282
VAL A 366
ILE A 389
GLY A 387
ILE A 312
None
0.94A 3oxwB-1fc9A:
undetectable
3oxwB-1fc9A:
14.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3QEL_D_QELD2_1
(NMDA GLUTAMATE
RECEPTOR SUBUNIT
GLUTAMATE [NMDA]
RECEPTOR SUBUNIT
EPSILON-2)
1fc9 PHOTOSYSTEM II D1
PROTEASE

(Tetradesmus
obliquus)
4 / 5 TYR A 279
THR A 258
PHE A 257
LEU A 308
None
1.22A 3qelC-1fc9A:
undetectable
3qelC-1fc9A:
23.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3U9F_H_CLMH221_0
(CHLORAMPHENICOL
ACETYLTRANSFERASE)
1fc9 PHOTOSYSTEM II D1
PROTEASE

(Tetradesmus
obliquus)
5 / 12 SER A 374
LEU A 282
VAL A 280
PHE A 297
VAL A 326
None
1.33A 3u9fH-1fc9A:
0.0
3u9fI-1fc9A:
undetectable
3u9fH-1fc9A:
19.02
3u9fI-1fc9A:
19.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4C5N_C_PXLC300_1
(PHOSPHOMETHYLPYRIMID
INE KINASE)
1fc9 PHOTOSYSTEM II D1
PROTEASE

(Tetradesmus
obliquus)
4 / 8 GLY A 307
GLY A 278
VAL A 363
VAL A 263
None
0.69A 4c5nC-1fc9A:
undetectable
4c5nC-1fc9A:
20.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4J6C_A_STRA501_1
(CYTOCHROME P450
MONOOXYGENASE)
1fc9 PHOTOSYSTEM II D1
PROTEASE

(Tetradesmus
obliquus)
5 / 11 ALA A 459
ALA A 266
ALA A 267
VAL A 363
LEU A 365
None
1.09A 4j6cA-1fc9A:
0.0
4j6cA-1fc9A:
22.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4J6C_B_STRB503_1
(CYTOCHROME P450
MONOOXYGENASE)
1fc9 PHOTOSYSTEM II D1
PROTEASE

(Tetradesmus
obliquus)
5 / 10 ALA A 459
ALA A 266
ALA A 267
VAL A 363
LEU A 365
None
1.09A 4j6cB-1fc9A:
0.0
4j6cB-1fc9A:
22.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4J6D_A_TESA503_1
(CYTOCHROME P450
MONOOXYGENASE)
1fc9 PHOTOSYSTEM II D1
PROTEASE

(Tetradesmus
obliquus)
5 / 12 ALA A 459
ALA A 266
ALA A 267
VAL A 363
LEU A 365
None
1.03A 4j6dA-1fc9A:
0.0
4j6dA-1fc9A:
22.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4J6D_B_TESB502_1
(CYTOCHROME P450
MONOOXYGENASE)
1fc9 PHOTOSYSTEM II D1
PROTEASE

(Tetradesmus
obliquus)
5 / 12 ALA A 459
ALA A 266
ALA A 267
VAL A 363
LEU A 365
None
1.02A 4j6dB-1fc9A:
0.0
4j6dB-1fc9A:
22.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4JBT_A_ASDA501_1
(CYTOCHROME P450
MONOOXYGENASE)
1fc9 PHOTOSYSTEM II D1
PROTEASE

(Tetradesmus
obliquus)
5 / 12 ALA A 459
ALA A 266
ALA A 267
VAL A 363
LEU A 365
None
1.00A 4jbtA-1fc9A:
0.0
4jbtA-1fc9A:
22.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4JBT_B_ASDB502_1
(CYTOCHROME P450
MONOOXYGENASE)
1fc9 PHOTOSYSTEM II D1
PROTEASE

(Tetradesmus
obliquus)
5 / 11 ALA A 459
ALA A 266
ALA A 267
VAL A 363
LEU A 365
None
1.00A 4jbtB-1fc9A:
0.0
4jbtB-1fc9A:
22.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4NJT_D_017D101_1
(PROTEASE)
1fc9 PHOTOSYSTEM II D1
PROTEASE

(Tetradesmus
obliquus)
5 / 11 LEU A 282
VAL A 366
ILE A 389
GLY A 387
ILE A 312
None
0.93A 4njtC-1fc9A:
undetectable
4njtC-1fc9A:
14.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4OR0_A_NPSA602_1
(SERUM ALBUMIN)
1fc9 PHOTOSYSTEM II D1
PROTEASE

(Tetradesmus
obliquus)
5 / 9 ALA A 340
ALA A 417
LEU A 399
LEU A 338
VAL A 337
None
1.27A 4or0A-1fc9A:
1.1
4or0A-1fc9A:
22.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QZU_A_RTLA201_0
(RETINOL-BINDING
PROTEIN 2)
1fc9 PHOTOSYSTEM II D1
PROTEASE

(Tetradesmus
obliquus)
5 / 12 PHE A 297
ALA A 293
VAL A 366
LEU A 377
LEU A 362
None
1.08A 4qzuA-1fc9A:
0.0
4qzuA-1fc9A:
17.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QZU_C_RTLC201_0
(RETINOL-BINDING
PROTEIN 2)
1fc9 PHOTOSYSTEM II D1
PROTEASE

(Tetradesmus
obliquus)
5 / 12 PHE A 297
ALA A 293
VAL A 366
LEU A 377
LEU A 362
None
1.06A 4qzuC-1fc9A:
0.0
4qzuC-1fc9A:
17.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4WQ4_A_ACTA403_0
(TRNA N6-ADENOSINE
THREONYLCARBAMOYLTRA
NSFERASE)
1fc9 PHOTOSYSTEM II D1
PROTEASE

(Tetradesmus
obliquus)
3 / 3 VAL A 215
LEU A 219
VAL A 202
None
0.56A 4wq4A-1fc9A:
undetectable
4wq4A-1fc9A:
24.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5BPH_A_ACTA403_0
(D-ALANINE--D-ALANINE
LIGASE)
1fc9 PHOTOSYSTEM II D1
PROTEASE

(Tetradesmus
obliquus)
4 / 6 ARG A 153
GLY A 409
SER A 410
LEU A 149
None
1.28A 5bphA-1fc9A:
undetectable
5bphA-1fc9A:
23.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEU_A_TRPA101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)
1fc9 PHOTOSYSTEM II D1
PROTEASE

(Tetradesmus
obliquus)
5 / 9 SER A 374
GLY A 431
ALA A 378
THR A 370
THR A 394
None
1.32A 5eeuA-1fc9A:
0.0
5eeuB-1fc9A:
0.0
5eeuA-1fc9A:
12.11
5eeuB-1fc9A:
12.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEU_T_TRPT101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)
1fc9 PHOTOSYSTEM II D1
PROTEASE

(Tetradesmus
obliquus)
5 / 10 GLY A 431
ALA A 378
THR A 370
THR A 394
SER A 374
None
1.32A 5eeuS-1fc9A:
undetectable
5eeuT-1fc9A:
0.0
5eeuS-1fc9A:
12.11
5eeuT-1fc9A:
12.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEV_T_TRPT101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)
1fc9 PHOTOSYSTEM II D1
PROTEASE

(Tetradesmus
obliquus)
5 / 10 GLY A 431
ALA A 378
THR A 370
THR A 394
SER A 374
None
1.32A 5eevS-1fc9A:
0.0
5eevT-1fc9A:
0.0
5eevS-1fc9A:
12.11
5eevT-1fc9A:
12.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEW_T_TRPT101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)
1fc9 PHOTOSYSTEM II D1
PROTEASE

(Tetradesmus
obliquus)
5 / 10 GLY A 431
ALA A 378
THR A 370
THR A 394
SER A 374
None
1.32A 5eewS-1fc9A:
0.0
5eewT-1fc9A:
0.0
5eewS-1fc9A:
12.11
5eewT-1fc9A:
12.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEX_T_TRPT101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)
1fc9 PHOTOSYSTEM II D1
PROTEASE

(Tetradesmus
obliquus)
5 / 10 GLY A 431
ALA A 378
THR A 370
THR A 394
SER A 374
None
1.32A 5eexS-1fc9A:
0.0
5eexT-1fc9A:
0.0
5eexS-1fc9A:
12.11
5eexT-1fc9A:
12.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEY_T_TRPT101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)
1fc9 PHOTOSYSTEM II D1
PROTEASE

(Tetradesmus
obliquus)
5 / 10 GLY A 431
ALA A 378
THR A 370
THR A 394
SER A 374
None
1.33A 5eeyS-1fc9A:
0.0
5eeyT-1fc9A:
0.0
5eeyS-1fc9A:
12.11
5eeyT-1fc9A:
12.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEZ_T_TRPT101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)
1fc9 PHOTOSYSTEM II D1
PROTEASE

(Tetradesmus
obliquus)
5 / 10 GLY A 431
ALA A 378
THR A 370
THR A 394
SER A 374
None
1.33A 5eezS-1fc9A:
0.0
5eezT-1fc9A:
0.0
5eezS-1fc9A:
12.11
5eezT-1fc9A:
12.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF0_T_TRPT101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)
1fc9 PHOTOSYSTEM II D1
PROTEASE

(Tetradesmus
obliquus)
5 / 10 GLY A 431
ALA A 378
THR A 370
THR A 394
SER A 374
None
1.33A 5ef0S-1fc9A:
0.0
5ef0T-1fc9A:
0.0
5ef0S-1fc9A:
12.11
5ef0T-1fc9A:
12.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF1_T_TRPT101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)
1fc9 PHOTOSYSTEM II D1
PROTEASE

(Tetradesmus
obliquus)
5 / 10 GLY A 431
ALA A 378
THR A 370
THR A 394
SER A 374
None
1.33A 5ef1S-1fc9A:
0.0
5ef1T-1fc9A:
0.0
5ef1S-1fc9A:
12.11
5ef1T-1fc9A:
12.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF2_T_TRPT101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)
1fc9 PHOTOSYSTEM II D1
PROTEASE

(Tetradesmus
obliquus)
5 / 10 GLY A 431
ALA A 378
THR A 370
THR A 394
SER A 374
None
1.33A 5ef2S-1fc9A:
0.0
5ef2T-1fc9A:
0.0
5ef2S-1fc9A:
12.11
5ef2T-1fc9A:
12.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF3_T_TRPT101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)
1fc9 PHOTOSYSTEM II D1
PROTEASE

(Tetradesmus
obliquus)
5 / 10 GLY A 431
ALA A 378
THR A 370
THR A 394
SER A 374
None
1.33A 5ef3S-1fc9A:
0.0
5ef3T-1fc9A:
0.0
5ef3S-1fc9A:
12.11
5ef3T-1fc9A:
12.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5L0Z_B_SAMB304_0
(PROBABLE RNA
METHYLTRANSFERASE,
TRMH FAMILY)
1fc9 PHOTOSYSTEM II D1
PROTEASE

(Tetradesmus
obliquus)
5 / 10 THR A 394
GLY A 431
ILE A 312
LEU A 377
ALA A 378
None
1.04A 5l0zB-1fc9A:
2.3
5l0zB-1fc9A:
23.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5NWW_A_ACAA18_2
(SCRFP-TAG,GP41)
1fc9 PHOTOSYSTEM II D1
PROTEASE

(Tetradesmus
obliquus)
3 / 3 LYS A 108
TRP A  89
SER A 105
None
1.28A 5nwwA-1fc9A:
0.0
5nwwA-1fc9A:
6.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5QGK_A_ACTA301_0
(PEROXISOMAL COENZYME
A DIPHOSPHATASE
NUDT7)
1fc9 PHOTOSYSTEM II D1
PROTEASE

(Tetradesmus
obliquus)
3 / 3 VAL A 337
TYR A 419
GLN A 420
None
0.73A 5qgkA-1fc9A:
0.0
5qgkA-1fc9A:
21.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5QGR_A_ACTA301_0
(PEROXISOMAL COENZYME
A DIPHOSPHATASE
NUDT7)
1fc9 PHOTOSYSTEM II D1
PROTEASE

(Tetradesmus
obliquus)
3 / 3 VAL A 337
TYR A 419
GLN A 420
None
0.71A 5qgrA-1fc9A:
0.0
5qgrA-1fc9A:
21.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5QGT_A_ACTA301_0
(PEROXISOMAL COENZYME
A DIPHOSPHATASE
NUDT7)
1fc9 PHOTOSYSTEM II D1
PROTEASE

(Tetradesmus
obliquus)
3 / 3 VAL A 337
TYR A 419
GLN A 420
None
0.73A 5qgtA-1fc9A:
0.0
5qgtA-1fc9A:
21.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5TUD_A_ERMA2001_1
(5-HYDROXYTRYPTAMINE
RECEPTOR 2B,SOLUBLE
CYTOCHROME B562
CHIMERA)
1fc9 PHOTOSYSTEM II D1
PROTEASE

(Tetradesmus
obliquus)
5 / 12 LEU A 330
ASP A 357
LEU A 462
LEU A 277
VAL A 305
None
0.99A 5tudA-1fc9A:
undetectable
5tudA-1fc9A:
22.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5UIG_A_EDTA501_0
(ADENOSINE RECEPTOR
A2A,SOLUBLE
CYTOCHROME
B562,ADENOSINE
RECEPTOR A2A)
1fc9 PHOTOSYSTEM II D1
PROTEASE

(Tetradesmus
obliquus)
4 / 6 ASN A 314
ASN A 367
ARG A 281
GLU A 441
None
1.34A 5uigA-1fc9A:
1.3
5uigA-1fc9A:
22.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VKQ_C_PCFC1801_0
(NO MECHANORECEPTOR
POTENTIAL C ISOFORM
L)
1fc9 PHOTOSYSTEM II D1
PROTEASE

(Tetradesmus
obliquus)
4 / 9 ILE A 400
LYS A 397
ILE A 427
ILE A 430
None
0.77A 5vkqB-1fc9A:
0.0
5vkqC-1fc9A:
0.0
5vkqB-1fc9A:
13.80
5vkqC-1fc9A:
13.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6DH0_A_017A101_0
(PROTEASE)
1fc9 PHOTOSYSTEM II D1
PROTEASE

(Tetradesmus
obliquus)
5 / 12 LEU A 388
GLY A 391
ASP A 311
VAL A 309
VAL A 363
None
0.73A 6dh0A-1fc9A:
undetectable
6dh0A-1fc9A:
13.28