SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '1fcp'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site

Query pattern: Residues from known binding site for annotated drug that match the hit pattern


(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID
Hit
Macromolecule
Res.
Matches
Interface HETATM RMSD Dali
Z-score
Seq.
Identity (%)
View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ESW_A_ACRA652_1
(AMYLOMALTASE)
1fcp PROTEIN (FERRIC
HYDROXAMATE UPTAKE
RECEPTOR)

(Escherichia
coli)
4 / 6 GLY A 706
GLY A 245
TYR A 313
SER A 700
None
None
FCI  A 750 (-3.7A)
None
0.98A 1eswA-1fcpA:
undetectable
1eswA-1fcpA:
22.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1OXR_A_AINA141_1
(PHOSPHOLIPASE A2
ISOFORM 3)
1fcp PROTEIN (FERRIC
HYDROXAMATE UPTAKE
RECEPTOR)

(Escherichia
coli)
4 / 4 LEU A 148
GLY A 141
ASP A 379
TYR A 105
None
1.13A 1oxrA-1fcpA:
0.0
1oxrA-1fcpA:
10.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ZZQ_B_ACTB861_0
(NITRIC-OXIDE
SYNTHASE, BRAIN)
1fcp PROTEIN (FERRIC
HYDROXAMATE UPTAKE
RECEPTOR)

(Escherichia
coli)
4 / 5 GLY A 653
GLN A 617
VAL A 698
SER A 651
None
1.13A 1zzqB-1fcpA:
0.0
1zzqB-1fcpA:
19.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ZZU_A_ACTA860_0
(NITRIC-OXIDE
SYNTHASE, BRAIN)
1fcp PROTEIN (FERRIC
HYDROXAMATE UPTAKE
RECEPTOR)

(Escherichia
coli)
4 / 5 GLY A 653
GLN A 617
VAL A 698
SER A 651
None
1.10A 1zzuA-1fcpA:
0.0
1zzuA-1fcpA:
19.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2HS2_B_017B203_1
(PROTEASE)
1fcp PROTEIN (FERRIC
HYDROXAMATE UPTAKE
RECEPTOR)

(Escherichia
coli)
4 / 6 PRO A  74
LEU A  70
ARG A  93
GLY A 147
None
1.22A 2hs2B-1fcpA:
0.0
2hs2B-1fcpA:
7.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2I91_A_ACTA601_0
(60 KDA SS-A/RO
RIBONUCLEOPROTEIN)
1fcp PROTEIN (FERRIC
HYDROXAMATE UPTAKE
RECEPTOR)

(Escherichia
coli)
4 / 7 TYR A 140
SER A  33
ALA A  34
ASN A 150
None
1.07A 2i91A-1fcpA:
undetectable
2i91A-1fcpA:
21.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2OD9_A_NCAA3721_0
(NAD-DEPENDENT
DEACETYLASE HST2)
1fcp PROTEIN (FERRIC
HYDROXAMATE UPTAKE
RECEPTOR)

(Escherichia
coli)
3 / 3 PHE A 166
PHE A 721
PHE A 723
None
0.79A 2od9A-1fcpA:
undetectable
2od9A-1fcpA:
19.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2QQG_A_NCAA3721_0
(NAD-DEPENDENT
DEACETYLASE HST2)
1fcp PROTEIN (FERRIC
HYDROXAMATE UPTAKE
RECEPTOR)

(Escherichia
coli)
3 / 3 PHE A 166
PHE A 721
PHE A 723
None
0.79A 2qqgA-1fcpA:
undetectable
2qqgA-1fcpA:
19.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2RCT_A_RTLA140_0
(RETINOL-BINDING
PROTEIN II, CELLULAR)
1fcp PROTEIN (FERRIC
HYDROXAMATE UPTAKE
RECEPTOR)

(Escherichia
coli)
5 / 12 ILE A 131
ALA A 129
TYR A 105
LEU A 148
GLN A 360
None
1.26A 2rctA-1fcpA:
0.8
2rctA-1fcpA:
11.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2V41_E_BEZE1222_0
(PEROXIREDOXIN 6.)
1fcp PROTEIN (FERRIC
HYDROXAMATE UPTAKE
RECEPTOR)

(Escherichia
coli)
4 / 7 PRO A 135
VAL A 136
SER A 137
GLU A 510
None
1.08A 2v41E-1fcpA:
undetectable
2v41F-1fcpA:
undetectable
2v41E-1fcpA:
16.55
2v41F-1fcpA:
16.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2V41_G_BEZG1222_0
(PEROXIREDOXIN 6.)
1fcp PROTEIN (FERRIC
HYDROXAMATE UPTAKE
RECEPTOR)

(Escherichia
coli)
4 / 8 PRO A 135
VAL A 136
SER A 137
GLU A 510
None
1.02A 2v41G-1fcpA:
undetectable
2v41H-1fcpA:
undetectable
2v41G-1fcpA:
16.55
2v41H-1fcpA:
16.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BJW_G_SVRG506_3
(PHOSPHOLIPASE A2)
1fcp PROTEIN (FERRIC
HYDROXAMATE UPTAKE
RECEPTOR)

(Escherichia
coli)
3 / 3 PRO A 223
PHE A 290
LYS A 226
None
1.19A 3bjwG-1fcpA:
0.0
3bjwG-1fcpA:
9.98
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3GSS_A_EAAA212_1
(GLUTATHIONE
S-TRANSFERASE P1-1)
1fcp PROTEIN (FERRIC
HYDROXAMATE UPTAKE
RECEPTOR)

(Escherichia
coli)
4 / 7 TYR A 140
VAL A 136
THR A  73
GLY A 147
None
0.94A 3gssA-1fcpA:
undetectable
3gssA-1fcpA:
15.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3GSS_B_EAAB211_1
(GLUTATHIONE
S-TRANSFERASE P1-1)
1fcp PROTEIN (FERRIC
HYDROXAMATE UPTAKE
RECEPTOR)

(Escherichia
coli)
4 / 7 TYR A 140
VAL A 136
THR A  73
GLY A 147
None
0.99A 3gssB-1fcpA:
undetectable
3gssB-1fcpA:
15.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3HLW_B_CE3B304_1
(CTX-M-9
EXTENDED-SPECTRUM
BETA-LACTAMASE)
1fcp PROTEIN (FERRIC
HYDROXAMATE UPTAKE
RECEPTOR)

(Escherichia
coli)
4 / 5 THR A 457
SER A 504
SER A 506
ARG A 488
None
1.42A 3hlwB-1fcpA:
undetectable
3hlwB-1fcpA:
17.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3U9F_B_CLMB221_0
(CHLORAMPHENICOL
ACETYLTRANSFERASE)
1fcp PROTEIN (FERRIC
HYDROXAMATE UPTAKE
RECEPTOR)

(Escherichia
coli)
5 / 12 SER A  33
SER A  51
LEU A  70
VAL A  66
VAL A  53
None
1.40A 3u9fB-1fcpA:
0.0
3u9fC-1fcpA:
0.0
3u9fB-1fcpA:
15.45
3u9fC-1fcpA:
15.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3U9F_E_CLME221_0
(CHLORAMPHENICOL
ACETYLTRANSFERASE)
1fcp PROTEIN (FERRIC
HYDROXAMATE UPTAKE
RECEPTOR)

(Escherichia
coli)
5 / 10 SER A  33
SER A  51
LEU A  70
VAL A  66
VAL A  53
None
1.44A 3u9fE-1fcpA:
0.0
3u9fE-1fcpA:
15.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3U9F_I_CLMI221_1
(CHLORAMPHENICOL
ACETYLTRANSFERASE)
1fcp PROTEIN (FERRIC
HYDROXAMATE UPTAKE
RECEPTOR)

(Escherichia
coli)
5 / 10 SER A  33
SER A  51
LEU A  70
VAL A  66
VAL A  53
None
1.44A 3u9fI-1fcpA:
0.0
3u9fI-1fcpA:
15.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3U9F_J_CLMJ221_0
(CHLORAMPHENICOL
ACETYLTRANSFERASE)
1fcp PROTEIN (FERRIC
HYDROXAMATE UPTAKE
RECEPTOR)

(Escherichia
coli)
5 / 12 SER A  33
SER A  51
LEU A  70
VAL A  66
VAL A  53
None
1.39A 3u9fJ-1fcpA:
0.0
3u9fK-1fcpA:
0.0
3u9fJ-1fcpA:
15.45
3u9fK-1fcpA:
15.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3U9F_N_CLMN221_0
(CHLORAMPHENICOL
ACETYLTRANSFERASE)
1fcp PROTEIN (FERRIC
HYDROXAMATE UPTAKE
RECEPTOR)

(Escherichia
coli)
5 / 11 SER A  33
SER A  51
LEU A  70
VAL A  66
VAL A  53
None
1.41A 3u9fN-1fcpA:
0.0
3u9fO-1fcpA:
0.0
3u9fN-1fcpA:
15.45
3u9fO-1fcpA:
15.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3U9F_P_CLMP221_0
(CHLORAMPHENICOL
ACETYLTRANSFERASE)
1fcp PROTEIN (FERRIC
HYDROXAMATE UPTAKE
RECEPTOR)

(Escherichia
coli)
5 / 9 SER A  33
SER A  51
LEU A  70
VAL A  66
VAL A  53
None
1.41A 3u9fP-1fcpA:
0.0
3u9fP-1fcpA:
15.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3U9F_R_CLMR221_0
(CHLORAMPHENICOL
ACETYLTRANSFERASE)
1fcp PROTEIN (FERRIC
HYDROXAMATE UPTAKE
RECEPTOR)

(Escherichia
coli)
5 / 10 SER A  33
SER A  51
LEU A  70
VAL A  66
VAL A  53
None
1.39A 3u9fR-1fcpA:
0.0
3u9fR-1fcpA:
15.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4IKJ_B_SUZB201_1
(TRANSTHYRETIN)
1fcp PROTEIN (FERRIC
HYDROXAMATE UPTAKE
RECEPTOR)

(Escherichia
coli)
4 / 8 SER A 181
SER A 183
ALA A 218
SER A 191
None
0.62A 4ikjA-1fcpA:
0.0
4ikjB-1fcpA:
0.3
4ikjA-1fcpA:
10.68
4ikjB-1fcpA:
10.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4IKK_A_SUZA201_1
(TRANSTHYRETIN)
1fcp PROTEIN (FERRIC
HYDROXAMATE UPTAKE
RECEPTOR)

(Escherichia
coli)
4 / 8 ALA A 218
SER A 191
SER A 181
SER A 183
None
0.59A 4ikkA-1fcpA:
0.0
4ikkB-1fcpA:
0.5
4ikkA-1fcpA:
10.68
4ikkB-1fcpA:
10.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4IKL_B_SUZB201_1
(TRANSTHYRETIN)
1fcp PROTEIN (FERRIC
HYDROXAMATE UPTAKE
RECEPTOR)

(Escherichia
coli)
4 / 8 SER A 181
SER A 183
ALA A 218
SER A 191
None
0.54A 4iklA-1fcpA:
0.0
4iklB-1fcpA:
undetectable
4iklA-1fcpA:
10.68
4iklB-1fcpA:
10.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4J7X_J_SASJ804_1
(SEPIAPTERIN
REDUCTASE)
1fcp PROTEIN (FERRIC
HYDROXAMATE UPTAKE
RECEPTOR)

(Escherichia
coli)
5 / 12 LEU A 332
LEU A 400
PRO A 398
GLN A 328
ASP A 320
None
1.31A 4j7xJ-1fcpA:
undetectable
4j7xJ-1fcpA:
17.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4JKU_B_ADNB500_2
(PROBABLE SUGAR
KINASE PROTEIN)
1fcp PROTEIN (FERRIC
HYDROXAMATE UPTAKE
RECEPTOR)

(Escherichia
coli)
4 / 4 SER A  49
ILE A 581
TYR A 502
PRO A  74
None
1.31A 4jkuB-1fcpA:
0.0
4jkuB-1fcpA:
19.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4K50_A_ACTA506_0
(RNA POLYMERASE
3D-POL)
1fcp PROTEIN (FERRIC
HYDROXAMATE UPTAKE
RECEPTOR)

(Escherichia
coli)
3 / 3 VAL A 346
GLY A 392
LYS A 344
None
0.68A 4k50A-1fcpA:
0.0
4k50A-1fcpA:
21.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4K50_E_ACTE504_0
(RNA POLYMERASE
3D-POL)
1fcp PROTEIN (FERRIC
HYDROXAMATE UPTAKE
RECEPTOR)

(Escherichia
coli)
3 / 3 VAL A 346
GLY A 392
LYS A 344
None
0.68A 4k50E-1fcpA:
undetectable
4k50E-1fcpA:
21.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4K50_I_ACTI504_0
(RNA POLYMERASE
3D-POL)
1fcp PROTEIN (FERRIC
HYDROXAMATE UPTAKE
RECEPTOR)

(Escherichia
coli)
3 / 3 VAL A 346
GLY A 392
LYS A 344
None
0.71A 4k50I-1fcpA:
0.0
4k50I-1fcpA:
21.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4K8P_A_ADNA401_2
(SUGAR KINASE)
1fcp PROTEIN (FERRIC
HYDROXAMATE UPTAKE
RECEPTOR)

(Escherichia
coli)
4 / 4 SER A  49
ILE A 581
TYR A 502
PRO A  74
None
1.32A 4k8pA-1fcpA:
0.0
4k8pA-1fcpA:
19.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4K8P_B_ADNB401_2
(SUGAR KINASE)
1fcp PROTEIN (FERRIC
HYDROXAMATE UPTAKE
RECEPTOR)

(Escherichia
coli)
4 / 4 SER A  49
ILE A 581
TYR A 502
PRO A  74
None
1.30A 4k8pB-1fcpA:
0.0
4k8pB-1fcpA:
19.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4K8T_A_ADNA401_2
(SUGAR KINASE)
1fcp PROTEIN (FERRIC
HYDROXAMATE UPTAKE
RECEPTOR)

(Escherichia
coli)
4 / 4 SER A  49
ILE A 581
TYR A 502
PRO A  74
None
1.31A 4k8tA-1fcpA:
0.0
4k8tA-1fcpA:
19.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4K8T_B_ADNB401_2
(SUGAR KINASE)
1fcp PROTEIN (FERRIC
HYDROXAMATE UPTAKE
RECEPTOR)

(Escherichia
coli)
4 / 4 SER A  49
ILE A 581
TYR A 502
PRO A  74
None
1.28A 4k8tB-1fcpA:
0.0
4k8tB-1fcpA:
19.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4K93_A_ADNA401_2
(SUGAR KINASE)
1fcp PROTEIN (FERRIC
HYDROXAMATE UPTAKE
RECEPTOR)

(Escherichia
coli)
4 / 4 SER A  49
ILE A 581
TYR A 502
PRO A  74
None
1.30A 4k93A-1fcpA:
undetectable
4k93A-1fcpA:
19.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4K93_B_ADNB402_2
(SUGAR KINASE)
1fcp PROTEIN (FERRIC
HYDROXAMATE UPTAKE
RECEPTOR)

(Escherichia
coli)
4 / 4 SER A  49
ILE A 581
TYR A 502
PRO A  74
None
1.30A 4k93B-1fcpA:
0.0
4k93B-1fcpA:
19.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4K9C_A_ADNA401_2
(SUGAR KINASE)
1fcp PROTEIN (FERRIC
HYDROXAMATE UPTAKE
RECEPTOR)

(Escherichia
coli)
4 / 4 SER A  49
ILE A 581
TYR A 502
PRO A  74
None
1.32A 4k9cA-1fcpA:
0.0
4k9cA-1fcpA:
19.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4K9C_B_ADNB401_2
(SUGAR KINASE)
1fcp PROTEIN (FERRIC
HYDROXAMATE UPTAKE
RECEPTOR)

(Escherichia
coli)
4 / 4 SER A  49
ILE A 581
TYR A 502
PRO A  74
None
1.30A 4k9cB-1fcpA:
0.0
4k9cB-1fcpA:
19.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4K9I_A_ADNA401_2
(SUGAR KINASE)
1fcp PROTEIN (FERRIC
HYDROXAMATE UPTAKE
RECEPTOR)

(Escherichia
coli)
4 / 4 SER A  49
ILE A 581
TYR A 502
PRO A  74
None
1.31A 4k9iA-1fcpA:
0.0
4k9iA-1fcpA:
19.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4K9I_B_ADNB401_2
(SUGAR KINASE)
1fcp PROTEIN (FERRIC
HYDROXAMATE UPTAKE
RECEPTOR)

(Escherichia
coli)
4 / 4 SER A  49
ILE A 581
TYR A 502
PRO A  74
None
1.31A 4k9iB-1fcpA:
0.0
4k9iB-1fcpA:
19.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KAD_A_ADNA401_2
(PROBABLE SUGAR
KINASE PROTEIN)
1fcp PROTEIN (FERRIC
HYDROXAMATE UPTAKE
RECEPTOR)

(Escherichia
coli)
4 / 4 SER A  49
ILE A 581
TYR A 502
PRO A  74
None
1.30A 4kadA-1fcpA:
0.0
4kadA-1fcpA:
19.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KAD_B_ADNB401_2
(PROBABLE SUGAR
KINASE PROTEIN)
1fcp PROTEIN (FERRIC
HYDROXAMATE UPTAKE
RECEPTOR)

(Escherichia
coli)
4 / 4 SER A  49
ILE A 581
TYR A 502
PRO A  74
None
1.31A 4kadB-1fcpA:
0.0
4kadB-1fcpA:
19.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4LBX_A_ADNA401_2
(PROBABLE SUGAR
KINASE PROTEIN)
1fcp PROTEIN (FERRIC
HYDROXAMATE UPTAKE
RECEPTOR)

(Escherichia
coli)
4 / 4 SER A  49
ILE A 581
TYR A 502
PRO A  74
None
1.30A 4lbxA-1fcpA:
0.0
4lbxA-1fcpA:
19.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4LBX_B_ADNB401_2
(PROBABLE SUGAR
KINASE PROTEIN)
1fcp PROTEIN (FERRIC
HYDROXAMATE UPTAKE
RECEPTOR)

(Escherichia
coli)
4 / 4 SER A  49
ILE A 581
TYR A 502
PRO A  74
None
1.29A 4lbxB-1fcpA:
0.0
4lbxB-1fcpA:
19.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4LC4_A_ADNA401_2
(PROBABLE SUGAR
KINASE PROTEIN)
1fcp PROTEIN (FERRIC
HYDROXAMATE UPTAKE
RECEPTOR)

(Escherichia
coli)
4 / 4 SER A  49
ILE A 581
TYR A 502
PRO A  74
None
1.28A 4lc4A-1fcpA:
undetectable
4lc4A-1fcpA:
19.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4LC4_B_ADNB401_2
(PROBABLE SUGAR
KINASE PROTEIN)
1fcp PROTEIN (FERRIC
HYDROXAMATE UPTAKE
RECEPTOR)

(Escherichia
coli)
4 / 4 SER A  49
ILE A 581
TYR A 502
PRO A  74
None
1.28A 4lc4B-1fcpA:
0.0
4lc4B-1fcpA:
19.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4OLM_A_198A1001_2
(ANDROGEN RECEPTOR)
1fcp PROTEIN (FERRIC
HYDROXAMATE UPTAKE
RECEPTOR)

(Escherichia
coli)
4 / 6 ASN A 103
ILE A  91
ILE A  92
VAL A  76
None
0.97A 4olmA-1fcpA:
undetectable
4olmA-1fcpA:
17.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4PD9_A_ADNA501_2
(NUPC FAMILY PROTEIN)
1fcp PROTEIN (FERRIC
HYDROXAMATE UPTAKE
RECEPTOR)

(Escherichia
coli)
3 / 3 THR A 477
ASN A 385
PHE A 115
None
None
FCI  A 750 ( 4.1A)
0.80A 4pd9A-1fcpA:
undetectable
4pd9A-1fcpA:
21.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4Z90_F_4LEF401_1
(GAMMA-AMINOBUTYRIC-A
CID RECEPTOR SUBUNIT
BETA-1)
1fcp PROTEIN (FERRIC
HYDROXAMATE UPTAKE
RECEPTOR)

(Escherichia
coli)
4 / 8 LEU A 247
LEU A 402
THR A 252
LEU A 262
None
0.78A 4z90F-1fcpA:
0.1
4z90G-1fcpA:
0.0
4z90H-1fcpA:
0.3
4z90I-1fcpA:
0.1
4z90J-1fcpA:
0.1
4z90F-1fcpA:
17.13
4z90G-1fcpA:
17.13
4z90H-1fcpA:
17.13
4z90I-1fcpA:
17.13
4z90J-1fcpA:
17.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4Z91_E_4LEE401_1
(GAMMA-AMINOBUTYRIC-A
CID RECEPTOR SUBUNIT
BETA-1)
1fcp PROTEIN (FERRIC
HYDROXAMATE UPTAKE
RECEPTOR)

(Escherichia
coli)
5 / 10 LEU A 247
LEU A 341
LEU A 402
THR A 252
LEU A 262
None
0.97A 4z91A-1fcpA:
0.2
4z91B-1fcpA:
0.0
4z91C-1fcpA:
0.2
4z91D-1fcpA:
0.1
4z91E-1fcpA:
0.1
4z91A-1fcpA:
17.13
4z91B-1fcpA:
17.13
4z91C-1fcpA:
17.13
4z91D-1fcpA:
17.13
4z91E-1fcpA:
17.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4Z91_E_4LEE401_1
(GAMMA-AMINOBUTYRIC-A
CID RECEPTOR SUBUNIT
BETA-1)
1fcp PROTEIN (FERRIC
HYDROXAMATE UPTAKE
RECEPTOR)

(Escherichia
coli)
5 / 10 LEU A 341
LEU A 402
THR A 252
LEU A 262
LEU A 247
None
0.95A 4z91A-1fcpA:
0.2
4z91B-1fcpA:
0.0
4z91C-1fcpA:
0.2
4z91D-1fcpA:
0.1
4z91E-1fcpA:
0.1
4z91A-1fcpA:
17.13
4z91B-1fcpA:
17.13
4z91C-1fcpA:
17.13
4z91D-1fcpA:
17.13
4z91E-1fcpA:
17.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4Z91_E_4LEE401_1
(GAMMA-AMINOBUTYRIC-A
CID RECEPTOR SUBUNIT
BETA-1)
1fcp PROTEIN (FERRIC
HYDROXAMATE UPTAKE
RECEPTOR)

(Escherichia
coli)
5 / 10 LEU A 341
LEU A 402
THR A 252
LEU A 262
LEU A 247
None
0.96A 4z91A-1fcpA:
0.2
4z91B-1fcpA:
0.0
4z91C-1fcpA:
0.2
4z91D-1fcpA:
0.1
4z91E-1fcpA:
0.1
4z91A-1fcpA:
17.13
4z91B-1fcpA:
17.13
4z91C-1fcpA:
17.13
4z91D-1fcpA:
17.13
4z91E-1fcpA:
17.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4Z91_E_4LEE401_1
(GAMMA-AMINOBUTYRIC-A
CID RECEPTOR SUBUNIT
BETA-1)
1fcp PROTEIN (FERRIC
HYDROXAMATE UPTAKE
RECEPTOR)

(Escherichia
coli)
5 / 10 LEU A 402
THR A 252
LEU A 262
LEU A 247
LEU A 341
None
0.91A 4z91A-1fcpA:
0.2
4z91B-1fcpA:
0.0
4z91C-1fcpA:
0.2
4z91D-1fcpA:
0.1
4z91E-1fcpA:
0.1
4z91A-1fcpA:
17.13
4z91B-1fcpA:
17.13
4z91C-1fcpA:
17.13
4z91D-1fcpA:
17.13
4z91E-1fcpA:
17.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4Z91_E_4LEE401_1
(GAMMA-AMINOBUTYRIC-A
CID RECEPTOR SUBUNIT
BETA-1)
1fcp PROTEIN (FERRIC
HYDROXAMATE UPTAKE
RECEPTOR)

(Escherichia
coli)
5 / 10 THR A 252
LEU A 262
LEU A 247
LEU A 341
LEU A 402
None
0.97A 4z91A-1fcpA:
0.2
4z91B-1fcpA:
0.0
4z91C-1fcpA:
0.2
4z91D-1fcpA:
0.1
4z91E-1fcpA:
0.1
4z91A-1fcpA:
17.13
4z91B-1fcpA:
17.13
4z91C-1fcpA:
17.13
4z91D-1fcpA:
17.13
4z91E-1fcpA:
17.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ZVC_A_BEZA301_0
(DIGUANYLATE CYCLASE
DOSC)
1fcp PROTEIN (FERRIC
HYDROXAMATE UPTAKE
RECEPTOR)

(Escherichia
coli)
4 / 8 ILE A  92
LEU A  90
ILE A 131
LEU A  70
None
0.82A 4zvcA-1fcpA:
undetectable
4zvcB-1fcpA:
undetectable
4zvcA-1fcpA:
10.96
4zvcB-1fcpA:
10.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5B2S_A_ACTA107_0
(CRISPR-ASSOCIATED
ENDONUCLEASE CAS9
GUIDE RNA)
1fcp PROTEIN (FERRIC
HYDROXAMATE UPTAKE
RECEPTOR)

(Escherichia
coli)
3 / 3 VAL A  52
THR A  54
ARG A 128
None
0.52A 5b2sB-1fcpA:
0.0
5b2sB-1fcpA:
19.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5B2T_A_ACTA108_0
(CRISPR-ASSOCIATED
ENDONUCLEASE CAS9
GUIDE RNA)
1fcp PROTEIN (FERRIC
HYDROXAMATE UPTAKE
RECEPTOR)

(Escherichia
coli)
3 / 3 VAL A  52
THR A  54
ARG A 128
None
0.49A 5b2tB-1fcpA:
undetectable
5b2tB-1fcpA:
19.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5GLM_A_ACTA613_0
(GLYCOSIDE HYDROLASE
FAMILY 43)
1fcp PROTEIN (FERRIC
HYDROXAMATE UPTAKE
RECEPTOR)

(Escherichia
coli)
3 / 3 ASP A 633
SER A 590
TYR A 629
None
0.82A 5glmA-1fcpA:
0.0
5glmA-1fcpA:
18.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5IKT_B_TLFB601_1
(PROSTAGLANDIN G/H
SYNTHASE 2)
1fcp PROTEIN (FERRIC
HYDROXAMATE UPTAKE
RECEPTOR)

(Escherichia
coli)
3 / 3 TYR A 243
TYR A 664
SER A 700
None
0.83A 5iktB-1fcpA:
0.0
5iktB-1fcpA:
21.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5JWA_H_ACTH614_0
(NADH DEHYDROGENASE,
PUTATIVE)
1fcp PROTEIN (FERRIC
HYDROXAMATE UPTAKE
RECEPTOR)

(Escherichia
coli)
4 / 6 VAL A 661
TYR A 697
VAL A 698
SER A 651
None
0.91A 5jwaH-1fcpA:
undetectable
5jwaH-1fcpA:
21.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5MM4_B_TA1B501_1
(TUBULIN BETA CHAIN)
1fcp PROTEIN (FERRIC
HYDROXAMATE UPTAKE
RECEPTOR)

(Escherichia
coli)
5 / 10 VAL A 152
GLU A 127
LEU A 375
ALA A  21
THR A 295
None
1.37A 5mm4B-1fcpA:
undetectable
5mm4B-1fcpA:
8.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5OJ0_A_9WTA801_0
(PENICILLIN-BINDING
PROTEIN 2X)
1fcp PROTEIN (FERRIC
HYDROXAMATE UPTAKE
RECEPTOR)

(Escherichia
coli)
5 / 12 SER A  84
GLN A 175
GLY A 242
THR A 241
GLN A 236
None
1.28A 5oj0A-1fcpA:
undetectable
5oj0A-1fcpA:
22.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VUN_A_ACTA804_0
(NITRIC OXIDE
SYNTHASE, BRAIN)
1fcp PROTEIN (FERRIC
HYDROXAMATE UPTAKE
RECEPTOR)

(Escherichia
coli)
4 / 5 GLY A 653
GLN A 617
VAL A 698
SER A 651
None
1.16A 5vunA-1fcpA:
0.0
5vunA-1fcpA:
19.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5YW0_A_ACTA411_0
(UNCHARACTERIZED
PROTEIN KDOO)
1fcp PROTEIN (FERRIC
HYDROXAMATE UPTAKE
RECEPTOR)

(Escherichia
coli)
3 / 3 LYS A 167
LEU A 173
ARG A 199
None
0.81A 5yw0A-1fcpA:
0.0
5yw0A-1fcpA:
19.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6CDU_G_EY4G502_0
(CHIMERIC ALPHA1GABAA
RECEPTOR)
1fcp PROTEIN (FERRIC
HYDROXAMATE UPTAKE
RECEPTOR)

(Escherichia
coli)
4 / 8 GLN A  44
VAL A  46
ILE A  50
THR A  35
None
0.96A 6cduG-1fcpA:
0.1
6cduH-1fcpA:
undetectable
6cduG-1fcpA:
17.48
6cduH-1fcpA:
17.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6G31_A_ZOLA401_0
(GERANYLGERANYL
PYROPHOSPHATE
SYNTHASE)
1fcp PROTEIN (FERRIC
HYDROXAMATE UPTAKE
RECEPTOR)

(Escherichia
coli)
4 / 7 ASP A 122
GLN A 175
LYS A 167
GLN A  62
None
0.91A 6g31A-1fcpA:
undetectable
6g31A-1fcpA:
7.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6G31_G_ZOLG401_0
(GERANYLGERANYL
PYROPHOSPHATE
SYNTHASE)
1fcp PROTEIN (FERRIC
HYDROXAMATE UPTAKE
RECEPTOR)

(Escherichia
coli)
4 / 7 ASP A 122
GLN A 175
LYS A 167
GLN A  62
None
0.93A 6g31G-1fcpA:
undetectable
6g31G-1fcpA:
7.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6MN4_D_AM2D301_0
(AMINOGLYCOSIDE
N(3)-ACETYLTRANSFERA
SE, AAC(3)-IVA)
1fcp PROTEIN (FERRIC
HYDROXAMATE UPTAKE
RECEPTOR)

(Escherichia
coli)
4 / 8 HIS A 621
ARG A 577
ASP A 601
GLU A 603
None
1.12A 6mn4D-1fcpA:
0.0
6mn4D-1fcpA:
16.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6MN4_F_AM2F301_0
(AMINOGLYCOSIDE
N(3)-ACETYLTRANSFERA
SE, AAC(3)-IVA)
1fcp PROTEIN (FERRIC
HYDROXAMATE UPTAKE
RECEPTOR)

(Escherichia
coli)
4 / 7 HIS A 621
ARG A 577
ASP A 601
GLU A 603
None
1.22A 6mn4F-1fcpA:
0.0
6mn4F-1fcpA:
16.45