SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '1fep'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1DF7_A_MTXA501_2
(DIHYDROFOLATE
REDUCTASE)		 1fep FERRIC ENTEROBACTIN
RECEPTOR
(Escherichia
coli) 		3 / 3 TRP A 627
ARG A 682
THR A 626
 None
 0.98A 1df7A-1fepA:
undetectable		 1df7A-1fepA:
13.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1JHQ_A_NIOA991_1
(NICOTINATE
MONONUCLEOTIDE:5,6-D
IMETHYLBENZIMIDAZOLE
PHOSPHORIBOSYLTRANSF
ERASE)		 1fep FERRIC ENTEROBACTIN
RECEPTOR
(Escherichia
coli) 		5 / 8 THR A 180
GLY A 149
GLY A 235
PHE A 189
ARG A 238
 None
 1.43A 1jhqA-1fepA:
undetectable		 1jhqA-1fepA:
19.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1JHV_A_NIOA991_1
(NICOTINATE
MONONUCLEOTIDE:5,6-D
IMETHYLBENZIMIDAZOLE
PHOSPHORIBOSYLTRANSF
ERASE)		 1fep FERRIC ENTEROBACTIN
RECEPTOR
(Escherichia
coli) 		5 / 8 THR A 180
GLY A 149
GLY A 235
PHE A 189
ARG A 238
 None
 1.45A 1jhvA-1fepA:
undetectable		 1jhvA-1fepA:
19.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1NT2_A_SAMA301_1
(FIBRILLARIN-LIKE
PRE-RRNA PROCESSING
PROTEIN)		 1fep FERRIC ENTEROBACTIN
RECEPTOR
(Escherichia
coli) 		3 / 3 THR A 708
GLU A 711
ASP A 676
 None
 0.53A 1nt2A-1fepA:
undetectable		 1nt2A-1fepA:
14.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1RG7_A_MTXA161_2
(DIHYDROFOLATE
REDUCTASE)		 1fep FERRIC ENTEROBACTIN
RECEPTOR
(Escherichia
coli) 		3 / 3 ILE A 508
ILE A 462
THR A 506
 None
 0.61A 1rg7A-1fepA:
undetectable		 1rg7A-1fepA:
12.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ZLQ_A_ACTA1502_0
(NICKEL-BINDING
PERIPLASMIC PROTEIN)		 1fep FERRIC ENTEROBACTIN
RECEPTOR
(Escherichia
coli) 		4 / 5 PRO A  90
GLY A 134
ASN A 135
GLY A 136
 None
 1.11A 1zlqA-1fepA:
0.0		 1zlqA-1fepA:
21.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2AVS_B_MK1B902_3
(POL POLYPROTEIN)		 1fep FERRIC ENTEROBACTIN
RECEPTOR
(Escherichia
coli) 		5 / 12 ASP A 110
GLY A 109
VAL A 142
ILE A  49
ILE A  84
 None
 1.13A 2avsB-1fepA:
undetectable		 2avsB-1fepA:
9.10
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2DXR_A_SORA1002_0
(LACTOTRANSFERRIN)		 1fep FERRIC ENTEROBACTIN
RECEPTOR
(Escherichia
coli) 		3 / 3 THR A 146
PRO A 115
TYR A 192
 None
 0.68A 2dxrA-1fepA:
undetectable		 2dxrA-1fepA:
18.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2PH9_A_GNTA301_1
(SOLUBLE
ACETYLCHOLINE
RECEPTOR)		 1fep FERRIC ENTEROBACTIN
RECEPTOR
(Escherichia
coli) 		4 / 7 GLN A 308
TYR A 289
TYR A 192
ILE A 233
 None
 1.34A 2ph9A-1fepA:
0.0
2ph9B-1fepA:
0.0		 2ph9A-1fepA:
14.62
2ph9B-1fepA:
14.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2UYQ_A_SAMA1311_0
(HYPOTHETICAL PROTEIN
ML2640)		 1fep FERRIC ENTEROBACTIN
RECEPTOR
(Escherichia
coli) 		4 / 7 ALA A 661
GLY A 673
ASP A 618
ARG A 616
 None
 0.63A 2uyqA-1fepA:
undetectable		 2uyqA-1fepA:
18.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ZQ9_A_CLSA11_1
(BETA-LACTAMASE
TOHO-1)		 1fep FERRIC ENTEROBACTIN
RECEPTOR
(Escherichia
coli) 		4 / 4 GLU A 564
ARG A 529
ASN A 530
ASP A 531
 None
 1.28A 2zq9A-1fepA:
0.0		 2zq9A-1fepA:
16.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3EEY_H_SAMH300_0
(PUTATIVE RRNA
METHYLASE)		 1fep FERRIC ENTEROBACTIN
RECEPTOR
(Escherichia
coli) 		5 / 12 THR A  58
GLY A  78
GLY A  64
ASN A  56
LEU A 599
 None
 1.14A 3eeyH-1fepA:
undetectable		 3eeyH-1fepA:
15.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3FRQ_A_ERYA195_1
(REPRESSOR PROTEIN
MPHR(A))		 1fep FERRIC ENTEROBACTIN
RECEPTOR
(Escherichia
coli) 		4 / 5 ASN A 534
ARG A 464
ASN A 441
ALA A 468
 None
 1.48A 3frqA-1fepA:
undetectable		 3frqA-1fepA:
14.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3RUN_A_CCSA165_0
(LYSOZYME)		 1fep FERRIC ENTEROBACTIN
RECEPTOR
(Escherichia
coli) 		3 / 3 ASN A 592
ALA A 561
LYS A 593
 None
 0.72A 3runA-1fepA:
0.0		 3runA-1fepA:
13.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4A99_D_MIYD392_1
(TETX2 PROTEIN)		 1fep FERRIC ENTEROBACTIN
RECEPTOR
(Escherichia
coli) 		4 / 5 SER A 112
GLN A  71
SER A  46
VAL A  45
 None
 1.21A 4a99D-1fepA:
0.1		 4a99D-1fepA:
21.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4AN2_A_EUIA1382_2
(DUAL SPECIFICITY
MITOGEN-ACTIVATED
PROTEIN KINASE
KINASE 1)		 1fep FERRIC ENTEROBACTIN
RECEPTOR
(Escherichia
coli) 		4 / 4 ASN A 534
SER A 590
LEU A 599
THR A 506
 None
 1.48A 4an2A-1fepA:
0.1		 4an2A-1fepA:
17.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4AX8_A_SAMA1474_0
(WBDD)		 1fep FERRIC ENTEROBACTIN
RECEPTOR
(Escherichia
coli) 		5 / 12 ASN A 230
ILE A 119
SER A  46
VAL A  45
ILE A  36
 None
 0.97A 4ax8A-1fepA:
undetectable		 4ax8A-1fepA:
21.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4AZV_A_SAMA1474_0
(WBDD)		 1fep FERRIC ENTEROBACTIN
RECEPTOR
(Escherichia
coli) 		5 / 12 ASN A 230
ILE A 119
SER A  46
VAL A  45
ILE A  36
 None
 0.96A 4azvA-1fepA:
undetectable		 4azvA-1fepA:
21.74
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4C49_B_HCYB1384_1
(CORTICOSTEROID-BINDI
NG GLOBULIN)		 1fep FERRIC ENTEROBACTIN
RECEPTOR
(Escherichia
coli) 		5 / 12 SER A 590
VAL A 563
THR A 526
ASN A  56
PHE A 528
 None
 1.48A 4c49B-1fepA:
1.2		 4c49B-1fepA:
19.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4FEU_B_KANB301_1
(AMINOGLYCOSIDE
3'-PHOSPHOTRANSFERAS
E APHA1-IAB)		 1fep FERRIC ENTEROBACTIN
RECEPTOR
(Escherichia
coli) 		4 / 7 ASN A  95
GLU A  80
ASP A 344
GLU A 310
 None
 1.08A 4feuB-1fepA:
undetectable		 4feuB-1fepA:
16.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4FEV_D_KAND301_1
(AMINOGLYCOSIDE
3'-PHOSPHOTRANSFERAS
E APHA1-IAB)		 1fep FERRIC ENTEROBACTIN
RECEPTOR
(Escherichia
coli) 		4 / 7 ASN A  95
GLU A  80
ASP A 344
GLU A 310
 None
 1.21A 4fevD-1fepA:
0.5		 4fevD-1fepA:
16.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4FEV_F_KANF301_1
(AMINOGLYCOSIDE
3'-PHOSPHOTRANSFERAS
E APHA1-IAB)		 1fep FERRIC ENTEROBACTIN
RECEPTOR
(Escherichia
coli) 		4 / 7 ASN A  95
GLU A  80
ASP A 344
GLU A 310
 None
 1.20A 4fevF-1fepA:
0.3		 4fevF-1fepA:
16.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4GKH_B_KANB301_1
(AMINOGLYCOSIDE
3'-PHOSPHOTRANSFERAS
E APHA1-IAB)		 1fep FERRIC ENTEROBACTIN
RECEPTOR
(Escherichia
coli) 		4 / 8 ASN A  95
GLU A  80
ASP A 344
GLU A 310
 None
 1.18A 4gkhB-1fepA:
0.7		 4gkhB-1fepA:
16.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4GKH_G_KANG301_1
(AMINOGLYCOSIDE
3'-PHOSPHOTRANSFERAS
E APHA1-IAB)		 1fep FERRIC ENTEROBACTIN
RECEPTOR
(Escherichia
coli) 		4 / 7 ASN A  95
GLU A  80
ASP A 344
GLU A 310
 None
 1.20A 4gkhG-1fepA:
0.6		 4gkhG-1fepA:
16.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4GKI_C_KANC301_1
(AMINOGLYCOSIDE
3'-PHOSPHOTRANSFERAS
E APHA1-IAB)		 1fep FERRIC ENTEROBACTIN
RECEPTOR
(Escherichia
coli) 		4 / 8 ASN A  95
GLU A  80
ASP A 344
GLU A 310
 None
 1.10A 4gkiC-1fepA:
0.2		 4gkiC-1fepA:
16.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5BW4_B_SAMB301_1
(16S RRNA
(ADENINE(1408)-N(1))
-METHYLTRANSFERASE)		 1fep FERRIC ENTEROBACTIN
RECEPTOR
(Escherichia
coli) 		3 / 3 ASP A 232
GLU A 117
SER A  93
 None
 0.80A 5bw4B-1fepA:
undetectable		 5bw4B-1fepA:
16.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5I1N_F_DVAF9_0
(D-VILLIN HEADPIECE
SUBDOMAIN
VILLIN-1)		 1fep FERRIC ENTEROBACTIN
RECEPTOR
(Escherichia
coli) 		3 / 3 ALA A  19
ASN A  22
LEU A  23
 None
 0.38A 5i1nC-1fepA:
undetectable		 5i1nC-1fepA:
4.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5I1N_G_DVAG9_0
(D-VILLIN HEADPIECE
SUBDOMAIN
VILLIN-1)		 1fep FERRIC ENTEROBACTIN
RECEPTOR
(Escherichia
coli) 		3 / 3 ALA A  19
ASN A  22
LEU A  23
 None
 0.37A 5i1nB-1fepA:
0.0		 5i1nB-1fepA:
4.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5I1O_F_DVAF9_0
(D-VILLIN HEADPIECE
SUBDOMAIN
VILLIN-1)		 1fep FERRIC ENTEROBACTIN
RECEPTOR
(Escherichia
coli) 		3 / 3 ALA A  19
ASN A  22
LEU A  23
 None
 0.37A 5i1oC-1fepA:
0.0		 5i1oC-1fepA:
4.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5I1O_H_DVAH9_0
(D-VILLIN HEADPIECE
SUBDOMAIN
VILLIN-1)		 1fep FERRIC ENTEROBACTIN
RECEPTOR
(Escherichia
coli) 		3 / 3 ALA A  19
ASN A  22
LEU A  23
 None
 0.45A 5i1oA-1fepA:
0.0		 5i1oA-1fepA:
4.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5I1P_F_DVAF9_0
(D-VILLIN HEADPIECE
SUBDOMAIN
VILLIN-1)		 1fep FERRIC ENTEROBACTIN
RECEPTOR
(Escherichia
coli) 		3 / 3 ALA A  19
ASN A  22
LEU A  23
 None
 0.34A 5i1pA-1fepA:
0.0		 5i1pA-1fepA:
4.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5I1P_G_DVAG9_0
(D-VILLIN HEADPIECE
SUBDOMAIN
VILLIN-1)		 1fep FERRIC ENTEROBACTIN
RECEPTOR
(Escherichia
coli) 		3 / 3 ALA A  19
ASN A  22
LEU A  23
 None
 0.39A 5i1pD-1fepA:
0.0		 5i1pD-1fepA:
4.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5KR2_A_ROCA101_2
(PROTEASE PR5-SQV)		 1fep FERRIC ENTEROBACTIN
RECEPTOR
(Escherichia
coli) 		5 / 11 ASN A 135
ALA A 468
ILE A 437
GLY A 439
ILE A 409
 None
 1.28A 5kr2B-1fepA:
undetectable		 5kr2B-1fepA:
9.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5N5D_B_SAMB303_1
(METHYLTRANSFERASE)		 1fep FERRIC ENTEROBACTIN
RECEPTOR
(Escherichia
coli) 		4 / 7 GLY A  27
PHE A 528
GLU A 511
ARG A 132
 None
 1.08A 5n5dB-1fepA:
undetectable		 5n5dB-1fepA:
15.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ONL_A_010A302_0
(YNDL)		 1fep FERRIC ENTEROBACTIN
RECEPTOR
(Escherichia
coli) 		4 / 5 GLU A 350
GLU A 368
GLU A 415
PHE A 413
 None
 1.22A 5onlA-1fepA:
0.0		 5onlA-1fepA:
15.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5UO7_A_H4BA802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 1fep FERRIC ENTEROBACTIN
RECEPTOR
(Escherichia
coli) 		4 / 8 SER A 612
MET A 621
VAL A 578
TRP A 613
 None
 1.34A 5uo7A-1fepA:
undetectable
5uo7B-1fepA:
undetectable		 5uo7A-1fepA:
20.56
5uo7B-1fepA:
20.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VLM_E_CVIE301_1
(REGULATORY PROTEIN
TETR)		 1fep FERRIC ENTEROBACTIN
RECEPTOR
(Escherichia
coli) 		4 / 7 GLY A 193
GLN A 287
TYR A 289
ASP A 196
 None
 1.05A 5vlmE-1fepA:
undetectable		 5vlmE-1fepA:
14.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6A4I_B_TRPB403_0
(TRYPTOPHAN
2,3-DIOXYGENASE)		 1fep FERRIC ENTEROBACTIN
RECEPTOR
(Escherichia
coli) 		4 / 7 ARG A 714
THR A 715
PRO A 164
PRO A 712
 None
 1.48A 6a4iB-1fepA:
undetectable		 6a4iB-1fepA:
19.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6DWD_A_GLYA715_0
(DEOXYNUCLEOSIDE
TRIPHOSPHATE
TRIPHOSPHOHYDROLASE
SAMHD1)		 1fep FERRIC ENTEROBACTIN
RECEPTOR
(Escherichia
coli) 		4 / 6 GLY A 136
ASN A 135
SER A  92
ARG A  94
 None
 1.04A 6dwdA-1fepA:
0.0
6dwdC-1fepA:
0.0		 6dwdA-1fepA:
19.97
6dwdC-1fepA:
19.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6GNG_B_QPSB601_3
(-)		 1fep FERRIC ENTEROBACTIN
RECEPTOR
(Escherichia
coli) 		3 / 3 ASP A 263
ASP A 201
ASN A 162
 None
 0.84A 6gngB-1fepA:
undetectable		 6gngB-1fepA:
22.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6HRJ_A_010A302_0
(YNDL)		 1fep FERRIC ENTEROBACTIN
RECEPTOR
(Escherichia
coli) 		4 / 5 GLU A 350
GLU A 368
GLU A 415
PHE A 413
 None
 1.23A 6hrjA-1fepA:
0.0		 6hrjA-1fepA:
15.43