SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '1ff3'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1NV8_B_SAMB301_0
(HEMK PROTEIN)		 1ff3 PEPTIDE METHIONINE
SULFOXIDE REDUCTASE
(Escherichia
coli) 		5 / 12 PHE A 114
GLY A 202
ILE A 200
VAL A 205
PRO A 120
 None
 1.04A 1nv8B-1ff3A:
undetectable		 1nv8B-1ff3A:
20.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2Q2H_B_ACTB501_0
(SECRETION CHAPERONE,
PHAGE-DISPLAY
DERIVED PEPTIDE)		 1ff3 PEPTIDE METHIONINE
SULFOXIDE REDUCTASE
(Escherichia
coli) 		3 / 3 ARG A  97
SER A  67
TYR A 181
 None
 1.06A 2q2hA-1ff3A:
0.0
2q2hB-1ff3A:
0.0		 2q2hA-1ff3A:
22.27
2q2hB-1ff3A:
22.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2XZ5_D_ACHD1211_0
(SOLUBLE
ACETYLCHOLINE
RECEPTOR)		 1ff3 PEPTIDE METHIONINE
SULFOXIDE REDUCTASE
(Escherichia
coli) 		4 / 8 THR A  90
GLN A 133
SER A  87
CYH A  86
 None
 1.14A 2xz5C-1ff3A:
0.0
2xz5D-1ff3A:
0.0		 2xz5C-1ff3A:
22.65
2xz5D-1ff3A:
22.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3N58_C_ADNC500_2
(ADENOSYLHOMOCYSTEINA
SE)		 1ff3 PEPTIDE METHIONINE
SULFOXIDE REDUCTASE
(Escherichia
coli) 		4 / 5 LEU A 207
GLN A 109
GLU A 116
HIS A 118
 None
 1.43A 3n58C-1ff3A:
undetectable		 3n58C-1ff3A:
19.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3PWW_A_ROCA1001_1
(ENDOTHIAPEPSIN)		 1ff3 PEPTIDE METHIONINE
SULFOXIDE REDUCTASE
(Escherichia
coli) 		5 / 12 ILE A 200
GLY A  71
ILE A  44
TYR A 139
ILE A  46
 None
 1.03A 3pwwA-1ff3A:
undetectable		 3pwwA-1ff3A:
20.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4CCQ_A_ACTA1317_0
(THIOREDOXIN
REDUCTASE)		 1ff3 PEPTIDE METHIONINE
SULFOXIDE REDUCTASE
(Escherichia
coli) 		3 / 3 LEU A 153
GLU A 154
SER A 152
 None
 0.84A 4ccqA-1ff3A:
undetectable		 4ccqA-1ff3A:
20.45