SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '1ffv'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1A7Y_A_DVAA8_0
(ACTINOMYCIN D)		 1ffv CUTL, MOLYBDOPROTEIN
OF CARBON MONOXIDE
DEHYDROGENASE
(Hydrogenophaga
pseudoflava) 		3 / 3 THR B 766
THR B 768
PRO B 765
 None
 0.85A 1a7yA-1ffvB:
undetectable		 1a7yA-1ffvB:
5.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1DSC_C_DVAC8_0
(ACTINOMYCIN D)		 1ffv CUTL, MOLYBDOPROTEIN
OF CARBON MONOXIDE
DEHYDROGENASE
(Hydrogenophaga
pseudoflava) 		3 / 3 THR B 766
THR B 768
PRO B 765
 None
 0.70A 1dscC-1ffvB:
undetectable		 1dscC-1ffvB:
5.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1EKJ_G_ACTG3002_0
(BETA-CARBONIC
ANHYDRASE)		 1ffv CUTS, IRON-SULFUR
PROTEIN OF CARBON
MONOXIDE
DEHYDROGENASE
CUTL, MOLYBDOPROTEIN
OF CARBON MONOXIDE
DEHYDROGENASE
(Hydrogenophaga
pseudoflava;
Hydrogenophaga
pseudoflava) 		4 / 8 CYH A 138
CYH A 101
GLY B 265
GLN B 524
 FES  A1907 ( 2.3A)
FES  A1907 (-2.3A)
None
PCD  B1920 (-3.5A)
 0.87A 1ekjG-1ffvA:
undetectable
1ekjH-1ffvA:
undetectable		 1ekjG-1ffvA:
20.80
1ekjH-1ffvA:
20.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1FJA_C_DVAC8_0
(ACTINOMYCIN D)		 1ffv CUTL, MOLYBDOPROTEIN
OF CARBON MONOXIDE
DEHYDROGENASE
(Hydrogenophaga
pseudoflava) 		3 / 3 THR B 766
THR B 768
PRO B 765
 None
 0.85A 1fjaC-1ffvB:
undetectable		 1fjaC-1ffvB:
5.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1FJA_D_DVAD8_0
(ACTINOMYCIN D)		 1ffv CUTL, MOLYBDOPROTEIN
OF CARBON MONOXIDE
DEHYDROGENASE
(Hydrogenophaga
pseudoflava) 		3 / 3 THR B 766
THR B 768
PRO B 765
 None
 0.85A 1fjaD-1ffvB:
undetectable		 1fjaD-1ffvB:
5.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1FK6_A_LNLA1201_1
(NON-SPECIFIC LIPID
TRANSFER PROTEIN)		 1ffv CUTL, MOLYBDOPROTEIN
OF CARBON MONOXIDE
DEHYDROGENASE
(Hydrogenophaga
pseudoflava) 		5 / 12 VAL B 400
LEU B 403
ALA B 319
ALA B 365
ILE B 362
 None
 1.01A 1fk6A-1ffvB:
undetectable		 1fk6A-1ffvB:
9.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1I3W_E_DVAE8_0
(ACTINOMYCIN D)		 1ffv CUTL, MOLYBDOPROTEIN
OF CARBON MONOXIDE
DEHYDROGENASE
(Hydrogenophaga
pseudoflava) 		3 / 3 THR B 766
THR B 768
PRO B 765
 None
 0.86A 1i3wE-1ffvB:
undetectable		 1i3wE-1ffvB:
5.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1I3W_G_DVAG8_0
(ACTINOMYCIN D)		 1ffv CUTL, MOLYBDOPROTEIN
OF CARBON MONOXIDE
DEHYDROGENASE
(Hydrogenophaga
pseudoflava) 		3 / 3 THR B 766
THR B 768
PRO B 765
 None
 0.83A 1i3wG-1ffvB:
undetectable		 1i3wG-1ffvB:
5.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1I3W_H_DVAH8_0
(ACTINOMYCIN D)		 1ffv CUTL, MOLYBDOPROTEIN
OF CARBON MONOXIDE
DEHYDROGENASE
(Hydrogenophaga
pseudoflava) 		3 / 3 THR B 766
THR B 768
PRO B 765
 None
 0.84A 1i3wH-1ffvB:
undetectable		 1i3wH-1ffvB:
5.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1IGX_A_EPAA700_2
(PROSTAGLANDIN
ENDOPEROXIDE H
SYNTHASE-1)		 1ffv CUTL, MOLYBDOPROTEIN
OF CARBON MONOXIDE
DEHYDROGENASE
(Hydrogenophaga
pseudoflava) 		4 / 8 VAL B 242
VAL B 246
SER B 250
ILE B 286
 None
 0.90A 1igxA-1ffvB:
0.7		 1igxA-1ffvB:
20.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1MNV_D_DVAD2_0
(ACTINOMYCIN D)		 1ffv CUTL, MOLYBDOPROTEIN
OF CARBON MONOXIDE
DEHYDROGENASE
(Hydrogenophaga
pseudoflava) 		3 / 3 THR B 768
PRO B 765
THR B 766
 None
 0.85A 1mnvD-1ffvB:
undetectable		 1mnvD-1ffvB:
5.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1MNV_D_DVAD8_0
(ACTINOMYCIN D)		 1ffv CUTL, MOLYBDOPROTEIN
OF CARBON MONOXIDE
DEHYDROGENASE
(Hydrogenophaga
pseudoflava) 		3 / 3 THR B 766
THR B 768
PRO B 765
 None
 0.82A 1mnvD-1ffvB:
undetectable		 1mnvD-1ffvB:
5.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1N4F_A_ASRA141_0
(LYSOZYME C)		 1ffv CUTL, MOLYBDOPROTEIN
OF CARBON MONOXIDE
DEHYDROGENASE
(Hydrogenophaga
pseudoflava) 		4 / 6 ASP B 679
GLY B 681
THR B 743
SER B 437
 None
 0.82A 1n4fA-1ffvB:
undetectable		 1n4fA-1ffvB:
9.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1N4F_A_ASRA141_0
(LYSOZYME C)		 1ffv CUTL, MOLYBDOPROTEIN
OF CARBON MONOXIDE
DEHYDROGENASE
(Hydrogenophaga
pseudoflava) 		4 / 6 ASP B 679
THR B 743
PRO B 744
SER B 437
 None
 0.91A 1n4fA-1ffvB:
undetectable		 1n4fA-1ffvB:
9.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1OIP_A_VIVA1278_0
(ALPHA-TOCOPHEROL
TRANSFER PROTEIN)		 1ffv CUTL, MOLYBDOPROTEIN
OF CARBON MONOXIDE
DEHYDROGENASE
(Hydrogenophaga
pseudoflava) 		5 / 12 LEU B 576
ILE B 534
LEU B 538
ILE B 507
ILE B 545
 None
 0.98A 1oipA-1ffvB:
undetectable		 1oipA-1ffvB:
17.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ONI_D_BEZD507_0
(14.5 KDA
TRANSLATIONAL
INHIBITOR PROTEIN)		 1ffv CUTL, MOLYBDOPROTEIN
OF CARBON MONOXIDE
DEHYDROGENASE
(Hydrogenophaga
pseudoflava) 		4 / 7 PHE B 431
ALA B 365
ILE B 396
ILE B 325
 None
 0.83A 1oniD-1ffvB:
0.0
1oniF-1ffvB:
0.0		 1oniD-1ffvB:
11.85
1oniF-1ffvB:
11.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1P6K_A_ACTA860_0
(NITRIC-OXIDE
SYNTHASE, BRAIN)		 1ffv CUTL, MOLYBDOPROTEIN
OF CARBON MONOXIDE
DEHYDROGENASE
(Hydrogenophaga
pseudoflava) 		4 / 6 GLY B 273
VAL B 241
ALA B 238
SER B 236
 None
 0.95A 1p6kA-1ffvB:
undetectable		 1p6kA-1ffvB:
20.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1Q23_G_FUAG708_2
(CHLORAMPHENICOL
ACETYLTRANSFERASE)		 1ffv CUTL, MOLYBDOPROTEIN
OF CARBON MONOXIDE
DEHYDROGENASE
(Hydrogenophaga
pseudoflava) 		3 / 3 VAL B  75
ALA B 120
HIS B  48
 None
 0.75A 1q23H-1ffvB:
0.0		 1q23H-1ffvB:
13.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1Q23_K_FUAK712_2
(CHLORAMPHENICOL
ACETYLTRANSFERASE)		 1ffv CUTL, MOLYBDOPROTEIN
OF CARBON MONOXIDE
DEHYDROGENASE
(Hydrogenophaga
pseudoflava) 		3 / 3 VAL B  75
ALA B 120
HIS B  48
 None
 0.78A 1q23L-1ffvB:
0.0		 1q23L-1ffvB:
13.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1QFI_A_DVAA8_0
(ACTINOMYCIN X2)		 1ffv CUTL, MOLYBDOPROTEIN
OF CARBON MONOXIDE
DEHYDROGENASE
(Hydrogenophaga
pseudoflava) 		3 / 3 THR B 766
THR B 768
PRO B 765
 None
 0.85A 1qfiA-1ffvB:
undetectable		 1qfiA-1ffvB:
5.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1R30_A_SAMA501_0
(BIOTIN SYNTHASE)		 1ffv CUTS, IRON-SULFUR
PROTEIN OF CARBON
MONOXIDE
DEHYDROGENASE
CUTL, MOLYBDOPROTEIN
OF CARBON MONOXIDE
DEHYDROGENASE
(Hydrogenophaga
pseudoflava;
Hydrogenophaga
pseudoflava) 		5 / 12 THR A 139
GLY B 691
ASP B  27
ILE B  31
LEU A  86
 FES  A1907 ( 4.7A)
None
None
None
None
 1.18A 1r30A-1ffvA:
undetectable		 1r30A-1ffvA:
18.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1RLB_E_REAE176_1
(RETINOL BINDING
PROTEIN)		 1ffv CUTM, FLAVOPROTEIN
OF CARBON MONOXIDE
DEHYDROGENASE
(Hydrogenophaga
pseudoflava) 		5 / 10 LEU C  94
ALA C 149
ALA C 134
VAL C  87
ASP C 115
 None
None
None
None
FAD  C1922 (-2.9A)
 1.17A 1rlbE-1ffvC:
0.0		 1rlbE-1ffvC:
20.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1T03_P_TFOP822_1
(POL POLYPROTEIN
SYNTHETIC
OLIGONUCLEOTIDE
PRIMER)		 1ffv CUTL, MOLYBDOPROTEIN
OF CARBON MONOXIDE
DEHYDROGENASE
CUTM, FLAVOPROTEIN
OF CARBON MONOXIDE
DEHYDROGENASE
CUTS, IRON-SULFUR
PROTEIN OF CARBON
MONOXIDE
DEHYDROGENASE
(Hydrogenophaga
pseudoflava) 		4 / 7 MET B  49
ASP B  50
LYS C   1
HIS A  27
 None
 0.95A 1t03A-1ffvB:
undetectable		 1t03A-1ffvB:
21.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1TH6_A_OINA401_1
(PHOSPHOLIPASE A2)		 1ffv CUTM, FLAVOPROTEIN
OF CARBON MONOXIDE
DEHYDROGENASE
(Hydrogenophaga
pseudoflava) 		4 / 7 GLY C 180
TRP C 181
HIS C 211
PRO C 173
 None
 1.11A 1th6A-1ffvC:
undetectable		 1th6A-1ffvC:
19.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1UNJ_L_DVAL2_0
(7-AMINO-ACTINOMYCIN
D)		 1ffv CUTL, MOLYBDOPROTEIN
OF CARBON MONOXIDE
DEHYDROGENASE
(Hydrogenophaga
pseudoflava) 		3 / 3 THR B 768
PRO B 765
THR B 766
 None
 0.85A 1unjL-1ffvB:
undetectable		 1unjL-1ffvB:
5.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1UNJ_L_DVAL8_0
(7-AMINO-ACTINOMYCIN
D)		 1ffv CUTL, MOLYBDOPROTEIN
OF CARBON MONOXIDE
DEHYDROGENASE
(Hydrogenophaga
pseudoflava) 		3 / 3 THR B 766
THR B 768
PRO B 765
 None
 0.80A 1unjL-1ffvB:
undetectable		 1unjL-1ffvB:
5.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1UNJ_R_DVAR2_0
(7-AMINO-ACTINOMYCIN
D)		 1ffv CUTL, MOLYBDOPROTEIN
OF CARBON MONOXIDE
DEHYDROGENASE
(Hydrogenophaga
pseudoflava) 		3 / 3 THR B 768
PRO B 765
THR B 766
 None
 0.83A 1unjR-1ffvB:
undetectable		 1unjR-1ffvB:
5.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1UNJ_R_DVAR8_0
(7-AMINO-ACTINOMYCIN
D)		 1ffv CUTL, MOLYBDOPROTEIN
OF CARBON MONOXIDE
DEHYDROGENASE
(Hydrogenophaga
pseudoflava) 		3 / 3 THR B 766
THR B 768
PRO B 765
 None
 0.82A 1unjR-1ffvB:
undetectable		 1unjR-1ffvB:
5.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1UNJ_W_DVAW8_0
(7-AMINO-ACTINOMYCIN
D)		 1ffv CUTL, MOLYBDOPROTEIN
OF CARBON MONOXIDE
DEHYDROGENASE
(Hydrogenophaga
pseudoflava) 		3 / 3 THR B 766
THR B 768
PRO B 765
 None
 0.76A 1unjW-1ffvB:
undetectable		 1unjW-1ffvB:
5.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1UNJ_X_DVAX2_0
(7-AMINO-ACTINOMYCIN
D)		 1ffv CUTL, MOLYBDOPROTEIN
OF CARBON MONOXIDE
DEHYDROGENASE
(Hydrogenophaga
pseudoflava) 		3 / 3 THR B 768
PRO B 765
THR B 766
 None
 0.81A 1unjX-1ffvB:
undetectable		 1unjX-1ffvB:
5.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1UNJ_X_DVAX8_0
(7-AMINO-ACTINOMYCIN
D)		 1ffv CUTL, MOLYBDOPROTEIN
OF CARBON MONOXIDE
DEHYDROGENASE
(Hydrogenophaga
pseudoflava) 		3 / 3 THR B 766
THR B 768
PRO B 765
 None
 0.79A 1unjX-1ffvB:
undetectable		 1unjX-1ffvB:
5.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1UNM_E_DVAE2_0
(7-AMINOACTINOMYCIN D)		 1ffv CUTL, MOLYBDOPROTEIN
OF CARBON MONOXIDE
DEHYDROGENASE
(Hydrogenophaga
pseudoflava) 		3 / 3 THR B 768
PRO B 765
THR B 766
 None
 0.80A 1unmE-1ffvB:
undetectable		 1unmE-1ffvB:
5.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1UNM_E_DVAE8_0
(7-AMINOACTINOMYCIN D)		 1ffv CUTL, MOLYBDOPROTEIN
OF CARBON MONOXIDE
DEHYDROGENASE
(Hydrogenophaga
pseudoflava) 		3 / 3 THR B 766
THR B 768
PRO B 765
 None
 0.77A 1unmE-1ffvB:
undetectable		 1unmE-1ffvB:
5.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1UNM_F_DVAF2_0
(7-AMINOACTINOMYCIN D)		 1ffv CUTL, MOLYBDOPROTEIN
OF CARBON MONOXIDE
DEHYDROGENASE
(Hydrogenophaga
pseudoflava) 		3 / 3 THR B 768
PRO B 765
THR B 766
 None
 0.84A 1unmF-1ffvB:
undetectable		 1unmF-1ffvB:
5.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1UNM_F_DVAF8_0
(7-AMINOACTINOMYCIN D)		 1ffv CUTL, MOLYBDOPROTEIN
OF CARBON MONOXIDE
DEHYDROGENASE
(Hydrogenophaga
pseudoflava) 		3 / 3 THR B 766
THR B 768
PRO B 765
 None
 0.79A 1unmF-1ffvB:
undetectable		 1unmF-1ffvB:
5.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1V3Q_E_2DIE290_1
(PURINE NUCLEOSIDE
PHOSPHORYLASE)		 1ffv CUTL, MOLYBDOPROTEIN
OF CARBON MONOXIDE
DEHYDROGENASE
(Hydrogenophaga
pseudoflava) 		5 / 10 GLY B 485
PHE B 387
GLY B 487
MET B 499
VAL B 483
 None
 1.01A 1v3qE-1ffvB:
undetectable		 1v3qE-1ffvB:
17.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1XIU_B_9CRB202_1
(RXR-LIKE PROTEIN)		 1ffv CUTL, MOLYBDOPROTEIN
OF CARBON MONOXIDE
DEHYDROGENASE
(Hydrogenophaga
pseudoflava) 		5 / 12 ILE B 574
ALA B 577
ALA B 578
LEU B 538
ALA B 640
 None
 0.99A 1xiuB-1ffvB:
undetectable		 1xiuB-1ffvB:
14.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1YAJ_B_BEZB12_0
(CES1 PROTEIN)		 1ffv CUTL, MOLYBDOPROTEIN
OF CARBON MONOXIDE
DEHYDROGENASE
(Hydrogenophaga
pseudoflava) 		4 / 4 GLY B 273
SER B 236
VAL B 245
LEU B  95
 None
 1.22A 1yajB-1ffvB:
undetectable		 1yajB-1ffvB:
20.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
209D_C_DVAC8_0
(N8-ACTINOMYCIN D)		 1ffv CUTL, MOLYBDOPROTEIN
OF CARBON MONOXIDE
DEHYDROGENASE
(Hydrogenophaga
pseudoflava) 		3 / 3 THR B 766
THR B 768
PRO B 765
 None
 0.85A 209dC-1ffvB:
undetectable		 209dC-1ffvB:
5.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ACL_G_REAG501_1
(RETINOIC ACID
RECEPTOR RXR-ALPHA)		 1ffv CUTL, MOLYBDOPROTEIN
OF CARBON MONOXIDE
DEHYDROGENASE
(Hydrogenophaga
pseudoflava) 		5 / 12 ILE B 574
ALA B 577
ALA B 578
ILE B 545
ALA B 640
 None
 0.94A 2aclG-1ffvB:
undetectable		 2aclG-1ffvB:
16.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ARM_A_OINA401_1
(PHOSPHOLIPASE A2
VRV-PL-VIIIA)		 1ffv CUTM, FLAVOPROTEIN
OF CARBON MONOXIDE
DEHYDROGENASE
(Hydrogenophaga
pseudoflava) 		4 / 7 GLY C 180
TRP C 181
HIS C 211
PRO C 173
 None
 1.10A 2armA-1ffvC:
undetectable		 2armA-1ffvC:
19.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2BM9_D_SAMD301_0
(CEPHALOSPORIN
HYDROXYLASE CMCI)		 1ffv CUTS, IRON-SULFUR
PROTEIN OF CARBON
MONOXIDE
DEHYDROGENASE
(Hydrogenophaga
pseudoflava) 		5 / 12 LEU A 116
LEU A 155
GLU A  91
GLY A  92
ALA A 147
 None
 1.14A 2bm9D-1ffvA:
undetectable		 2bm9D-1ffvA:
19.34
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2BR4_A_SAMA301_1
(CEPHALOSPORIN
HYDROXYLASE CMCI)		 1ffv CUTS, IRON-SULFUR
PROTEIN OF CARBON
MONOXIDE
DEHYDROGENASE
CUTL, MOLYBDOPROTEIN
OF CARBON MONOXIDE
DEHYDROGENASE
(Hydrogenophaga
pseudoflava;
Hydrogenophaga
pseudoflava) 		3 / 3 LYS A   3
ASP B 128
ASP B  50
 None
 1.03A 2br4A-1ffvA:
undetectable		 2br4A-1ffvA:
19.34
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2BR4_B_SAMB301_0
(CEPHALOSPORIN
HYDROXYLASE CMCI)		 1ffv CUTS, IRON-SULFUR
PROTEIN OF CARBON
MONOXIDE
DEHYDROGENASE
CUTL, MOLYBDOPROTEIN
OF CARBON MONOXIDE
DEHYDROGENASE
(Hydrogenophaga
pseudoflava;
Hydrogenophaga
pseudoflava) 		5 / 12 GLU B 215
GLY B 265
ASN B  36
ARG B  29
CYH A 138
 None
None
None
None
FES  A1907 ( 2.3A)
 1.14A 2br4B-1ffvB:
undetectable		 2br4B-1ffvB:
14.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2HMA_A_SAMA375_0
(PROBABLE TRNA
(5-METHYLAMINOMETHYL
-2-THIOURIDYLATE)-ME
THYLTRANSFERASE)		 1ffv CUTM, FLAVOPROTEIN
OF CARBON MONOXIDE
DEHYDROGENASE
(Hydrogenophaga
pseudoflava) 		5 / 11 GLY C 114
SER C  36
ASN C  55
THR C 111
GLY C 110
 FAD  C1922 (-3.3A)
FAD  C1922 (-3.0A)
None
FAD  C1922 (-3.0A)
FAD  C1922 (-3.7A)
 1.19A 2hmaA-1ffvC:
undetectable		 2hmaA-1ffvC:
19.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2Q6H_A_CXXA802_1
(TRANSPORTER)		 1ffv CUTM, FLAVOPROTEIN
OF CARBON MONOXIDE
DEHYDROGENASE
(Hydrogenophaga
pseudoflava) 		4 / 7 ILE C 130
ARG C 171
PHE C 136
ILE C 170
 None
 1.15A 2q6hA-1ffvC:
0.2		 2q6hA-1ffvC:
20.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2VCV_L_ASDL1224_1
(GLUTATHIONE
S-TRANSFERASE A3)		 1ffv CUTL, MOLYBDOPROTEIN
OF CARBON MONOXIDE
DEHYDROGENASE
(Hydrogenophaga
pseudoflava) 		4 / 7 PHE B 339
LEU B 157
ALA B 338
PHE B 110
 None
 1.07A 2vcvL-1ffvB:
0.0		 2vcvL-1ffvB:
14.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2W8Y_A_486A1000_2
(PROGESTERONE
RECEPTOR)		 1ffv CUTL, MOLYBDOPROTEIN
OF CARBON MONOXIDE
DEHYDROGENASE
(Hydrogenophaga
pseudoflava) 		4 / 7 LEU B 103
LEU B 249
MET B  49
MET B  92
 None
 1.09A 2w8yA-1ffvB:
0.0		 2w8yA-1ffvB:
15.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2WA2_B_SAMB1267_0
(NON-STRUCTURAL
PROTEIN 5)		 1ffv CUTS, IRON-SULFUR
PROTEIN OF CARBON
MONOXIDE
DEHYDROGENASE
CUTL, MOLYBDOPROTEIN
OF CARBON MONOXIDE
DEHYDROGENASE
(Hydrogenophaga
pseudoflava;
Hydrogenophaga
pseudoflava) 		5 / 12 GLY A  98
GLY B 695
GLY A 140
THR B 698
ILE B 693
 None
ARO  B 384 ( 3.9A)
None
None
None
 0.95A 2wa2B-1ffvA:
undetectable		 2wa2B-1ffvA:
22.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2Y6R_C_CTCC1385_0
(TETX2 PROTEIN)		 1ffv CUTS, IRON-SULFUR
PROTEIN OF CARBON
MONOXIDE
DEHYDROGENASE
CUTL, MOLYBDOPROTEIN
OF CARBON MONOXIDE
DEHYDROGENASE
(Hydrogenophaga
pseudoflava;
Hydrogenophaga
pseudoflava) 		5 / 12 GLN B 692
ARG A 137
SER B 564
PRO B 759
GLY B 700
 PCD  B1920 (-3.4A)
None
PCD  B1920 (-4.0A)
None
None
 1.12A 2y6rC-1ffvB:
undetectable		 2y6rC-1ffvB:
16.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3AQI_A_CHDA2_0
(FERROCHELATASE)		 1ffv CUTL, MOLYBDOPROTEIN
OF CARBON MONOXIDE
DEHYDROGENASE
(Hydrogenophaga
pseudoflava) 		4 / 6 ARG B 309
PRO B 734
GLY B 696
TRP B 736
 CSZ  B 385 ( 4.6A)
None
ARO  B 384 ( 3.6A)
None
 1.35A 3aqiA-1ffvB:
undetectable		 3aqiA-1ffvB:
17.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BRF_A_SORA2_0
(LIN-12 AND GLP-1
PHENOTYPE PROTEIN 1,
ISOFORM A)		 1ffv CUTM, FLAVOPROTEIN
OF CARBON MONOXIDE
DEHYDROGENASE
(Hydrogenophaga
pseudoflava) 		3 / 3 LYS C 276
LYS C 240
VAL C 243
 None
 1.10A 3brfA-1ffvC:
0.0		 3brfA-1ffvC:
20.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3DOU_A_SAMA1_1
(RIBOSOMAL RNA LARGE
SUBUNIT
METHYLTRANSFERASE J)		 1ffv CUTL, MOLYBDOPROTEIN
OF CARBON MONOXIDE
DEHYDROGENASE
(Hydrogenophaga
pseudoflava) 		3 / 3 ASP B 739
ASP B 449
ASP B 679
 None
 0.74A 3douA-1ffvB:
undetectable		 3douA-1ffvB:
11.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3EKW_B_DR7B100_1
(PROTEASE)		 1ffv CUTL, MOLYBDOPROTEIN
OF CARBON MONOXIDE
DEHYDROGENASE
(Hydrogenophaga
pseudoflava) 		6 / 10 ARG B  22
ALA B 515
ILE B 507
PRO B 541
ALA B 535
ILE B 534
 None
 1.42A 3ekwA-1ffvB:
undetectable		 3ekwA-1ffvB:
9.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ELW_A_SAMA4633_0
(METHYLTRANSFERASE)		 1ffv CUTS, IRON-SULFUR
PROTEIN OF CARBON
MONOXIDE
DEHYDROGENASE
CUTL, MOLYBDOPROTEIN
OF CARBON MONOXIDE
DEHYDROGENASE
(Hydrogenophaga
pseudoflava;
Hydrogenophaga
pseudoflava) 		5 / 12 GLY A  98
GLY B 695
GLY A 140
THR B 698
ILE B 693
 None
ARO  B 384 ( 3.9A)
None
None
None
 0.93A 3elwA-1ffvA:
undetectable		 3elwA-1ffvA:
19.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3EM4_V_DR7V100_2
(PROTEASE)		 1ffv CUTM, FLAVOPROTEIN
OF CARBON MONOXIDE
DEHYDROGENASE
(Hydrogenophaga
pseudoflava) 		5 / 10 ASP C  80
ILE C  63
GLY C  62
LEU C  60
ILE C 112
 None
 0.75A 3em4V-1ffvC:
undetectable		 3em4V-1ffvC:
13.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3FXR_A_ASCA3001_0
(LYSR TYPE REGULATOR
OF TSAMBCD)		 1ffv CUTM, FLAVOPROTEIN
OF CARBON MONOXIDE
DEHYDROGENASE
(Hydrogenophaga
pseudoflava) 		4 / 8 HIS C 211
ARG C 213
ALA C 131
PRO C 173
 None
 0.99A 3fxrA-1ffvC:
0.0		 3fxrA-1ffvC:
24.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3G0B_A_T22A800_1
(DIPEPTIDYL PEPTIDASE
4)		 1ffv CUTL, MOLYBDOPROTEIN
OF CARBON MONOXIDE
DEHYDROGENASE
(Hydrogenophaga
pseudoflava) 		5 / 12 GLU B 434
SER B 745
TYR B 651
ASN B 648
HIS B 747
 None
 1.29A 3g0bA-1ffvB:
undetectable		 3g0bA-1ffvB:
20.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3G0B_B_T22B800_1
(DIPEPTIDYL PEPTIDASE
4)		 1ffv CUTL, MOLYBDOPROTEIN
OF CARBON MONOXIDE
DEHYDROGENASE
(Hydrogenophaga
pseudoflava) 		5 / 12 GLU B 434
SER B 745
TYR B 651
ASN B 648
HIS B 747
 None
 1.30A 3g0bB-1ffvB:
2.4		 3g0bB-1ffvB:
20.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3G0B_C_T22C800_1
(DIPEPTIDYL PEPTIDASE
4)		 1ffv CUTL, MOLYBDOPROTEIN
OF CARBON MONOXIDE
DEHYDROGENASE
(Hydrogenophaga
pseudoflava) 		5 / 12 GLU B 434
SER B 745
TYR B 651
ASN B 648
HIS B 747
 None
 1.29A 3g0bC-1ffvB:
undetectable		 3g0bC-1ffvB:
20.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3G0B_D_T22D800_1
(DIPEPTIDYL PEPTIDASE
4)		 1ffv CUTL, MOLYBDOPROTEIN
OF CARBON MONOXIDE
DEHYDROGENASE
(Hydrogenophaga
pseudoflava) 		5 / 12 GLU B 434
SER B 745
TYR B 651
ASN B 648
HIS B 747
 None
 1.30A 3g0bD-1ffvB:
undetectable		 3g0bD-1ffvB:
20.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3GV1_A_BEZA302_0
(DISULFIDE
INTERCHANGE PROTEIN)		 1ffv CUTL, MOLYBDOPROTEIN
OF CARBON MONOXIDE
DEHYDROGENASE
(Hydrogenophaga
pseudoflava) 		4 / 6 PRO B 646
HIS B 747
ALA B 486
PRO B 488
 None
 1.19A 3gv1A-1ffvB:
0.0
3gv1C-1ffvB:
0.0		 3gv1A-1ffvB:
12.76
3gv1C-1ffvB:
12.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3GV1_B_BEZB301_0
(DISULFIDE
INTERCHANGE PROTEIN)		 1ffv CUTL, MOLYBDOPROTEIN
OF CARBON MONOXIDE
DEHYDROGENASE
(Hydrogenophaga
pseudoflava) 		4 / 6 ALA B 486
PRO B 488
PRO B 646
HIS B 747
 None
 1.23A 3gv1A-1ffvB:
0.0
3gv1B-1ffvB:
0.0		 3gv1A-1ffvB:
12.76
3gv1B-1ffvB:
12.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3GYQ_A_SAMA270_0
(RRNA
(ADENOSINE-2'-O-)-ME
THYLTRANSFERASE)		 1ffv CUTL, MOLYBDOPROTEIN
OF CARBON MONOXIDE
DEHYDROGENASE
(Hydrogenophaga
pseudoflava) 		5 / 12 LEU B 328
ALA B 318
GLY B 315
ILE B 325
LEU B 403
 None
 1.22A 3gyqA-1ffvB:
undetectable
3gyqB-1ffvB:
undetectable		 3gyqA-1ffvB:
16.88
3gyqB-1ffvB:
16.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3GYQ_B_SAMB270_0
(RRNA
(ADENOSINE-2'-O-)-ME
THYLTRANSFERASE)		 1ffv CUTL, MOLYBDOPROTEIN
OF CARBON MONOXIDE
DEHYDROGENASE
(Hydrogenophaga
pseudoflava) 		5 / 11 LEU B 328
ALA B 318
GLY B 315
ILE B 325
LEU B 403
 None
 1.13A 3gyqB-1ffvB:
undetectable		 3gyqB-1ffvB:
16.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3HS6_B_EPAB1_2
(PROSTAGLANDIN G/H
SYNTHASE 2)		 1ffv CUTL, MOLYBDOPROTEIN
OF CARBON MONOXIDE
DEHYDROGENASE
(Hydrogenophaga
pseudoflava) 		4 / 7 VAL B 242
VAL B 246
LEU B 249
SER B 250
 None
 0.68A 3hs6B-1ffvB:
0.0		 3hs6B-1ffvB:
19.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3K9F_H_LFXH0_1
(DNA TOPOISOMERASE 4
SUBUNIT A
DNA TOPOISOMERASE 4
SUBUNIT B)		 1ffv CUTM, FLAVOPROTEIN
OF CARBON MONOXIDE
DEHYDROGENASE
(Hydrogenophaga
pseudoflava) 		4 / 6 SER C 129
ARG C 145
GLU C 162
GLU C 165
 None
 1.14A 3k9fA-1ffvC:
0.8
3k9fB-1ffvC:
0.4
3k9fD-1ffvC:
undetectable		 3k9fA-1ffvC:
20.79
3k9fB-1ffvC:
20.79
3k9fD-1ffvC:
23.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KO0_D_TFPD201_1
(PROTEIN S100-A4)		 1ffv CUTL, MOLYBDOPROTEIN
OF CARBON MONOXIDE
DEHYDROGENASE
CUTS, IRON-SULFUR
PROTEIN OF CARBON
MONOXIDE
DEHYDROGENASE
(Hydrogenophaga
pseudoflava) 		4 / 8 GLY B  33
CYH A  47
CYH A 136
PHE B 268
 None
FES  A1908 (-2.2A)
FES  A1907 (-2.3A)
PCD  B1920 (-3.6A)
 0.99A 3ko0D-1ffvB:
undetectable
3ko0E-1ffvB:
0.0		 3ko0D-1ffvB:
8.53
3ko0E-1ffvB:
8.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KO0_J_TFPJ201_1
(PROTEIN S100-A4)		 1ffv CUTL, MOLYBDOPROTEIN
OF CARBON MONOXIDE
DEHYDROGENASE
CUTS, IRON-SULFUR
PROTEIN OF CARBON
MONOXIDE
DEHYDROGENASE
(Hydrogenophaga
pseudoflava) 		4 / 8 GLY B  33
CYH A  47
CYH A 136
PHE B 268
 None
FES  A1908 (-2.2A)
FES  A1907 (-2.3A)
PCD  B1920 (-3.6A)
 1.00A 3ko0B-1ffvB:
0.4
3ko0J-1ffvB:
0.0		 3ko0B-1ffvB:
8.53
3ko0J-1ffvB:
8.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3LFA_A_1N1A361_1
(MITOGEN-ACTIVATED
PROTEIN KINASE 14)		 1ffv CUTS, IRON-SULFUR
PROTEIN OF CARBON
MONOXIDE
DEHYDROGENASE
(Hydrogenophaga
pseudoflava) 		4 / 8 VAL A   8
ALA A  66
THR A  23
LEU A  25
 None
 0.44A 3lfaA-1ffvA:
undetectable		 3lfaA-1ffvA:
18.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3N8Y_A_DIFA701_1
(PROSTAGLANDIN G/H
SYNTHASE 1)		 1ffv CUTM, FLAVOPROTEIN
OF CARBON MONOXIDE
DEHYDROGENASE
(Hydrogenophaga
pseudoflava) 		5 / 11 VAL C 166
LEU C 161
GLY C 113
ALA C  74
LEU C  60
 FAD  C1922 (-4.0A)
FAD  C1922 (-4.6A)
None
FAD  C1922 ( 3.7A)
None
 1.18A 3n8yA-1ffvC:
undetectable		 3n8yA-1ffvC:
18.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3OHT_A_1N1A2000_1
(P38A)		 1ffv CUTM, FLAVOPROTEIN
OF CARBON MONOXIDE
DEHYDROGENASE
(Hydrogenophaga
pseudoflava) 		5 / 12 ILE C 112
MET C 167
VAL C  14
ILE C 170
ALA C 117
 None
None
None
None
FAD  C1922 (-3.2A)
 1.06A 3ohtA-1ffvC:
undetectable
3ohtB-1ffvC:
undetectable		 3ohtA-1ffvC:
20.72
3ohtB-1ffvC:
20.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3OU7_B_SAMB300_1
(SAM-DEPENDENT
METHYLTRANSFERASE)		 1ffv CUTL, MOLYBDOPROTEIN
OF CARBON MONOXIDE
DEHYDROGENASE
(Hydrogenophaga
pseudoflava) 		3 / 3 TYR B 557
ASP B 501
ASP B 645
 None
 0.78A 3ou7B-1ffvB:
undetectable		 3ou7B-1ffvB:
15.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3P97_C_SAMC263_0
(NON-STRUCTURAL
PROTEIN 5)		 1ffv CUTS, IRON-SULFUR
PROTEIN OF CARBON
MONOXIDE
DEHYDROGENASE
CUTL, MOLYBDOPROTEIN
OF CARBON MONOXIDE
DEHYDROGENASE
(Hydrogenophaga
pseudoflava;
Hydrogenophaga
pseudoflava) 		5 / 12 GLY A  98
GLY B 695
GLY A 140
THR B 698
ILE B 693
 None
ARO  B 384 ( 3.9A)
None
None
None
 0.89A 3p97C-1ffvA:
undetectable		 3p97C-1ffvA:
19.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3R0L_D_ACTD127_0
(PHOSPHOLIPASE A2 CB)		 1ffv CUTL, MOLYBDOPROTEIN
OF CARBON MONOXIDE
DEHYDROGENASE
(Hydrogenophaga
pseudoflava) 		4 / 5 PHE B 607
ILE B 622
GLY B 539
HIS B 582
 None
 1.14A 3r0lD-1ffvB:
undetectable		 3r0lD-1ffvB:
8.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3RLB_B_VIBB187_1
(THIT)		 1ffv CUTL, MOLYBDOPROTEIN
OF CARBON MONOXIDE
DEHYDROGENASE
(Hydrogenophaga
pseudoflava) 		5 / 12 ILE B 396
GLU B 397
TYR B 360
GLY B 323
ASN B 418
 None
 1.35A 3rlbB-1ffvB:
0.0		 3rlbB-1ffvB:
13.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3T3Z_C_9PLC501_1
(CYTOCHROME P450 2E1)		 1ffv CUTL, MOLYBDOPROTEIN
OF CARBON MONOXIDE
DEHYDROGENASE
(Hydrogenophaga
pseudoflava) 		4 / 5 PHE B 431
PHE B 353
ALA B 392
LEU B 328
 None
 1.11A 3t3zC-1ffvB:
undetectable		 3t3zC-1ffvB:
19.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3UVV_B_9CRB501_1
(RETINOIC ACID
RECEPTOR RXR-ALPHA)		 1ffv CUTL, MOLYBDOPROTEIN
OF CARBON MONOXIDE
DEHYDROGENASE
(Hydrogenophaga
pseudoflava) 		5 / 12 ILE B 574
ALA B 577
ALA B 578
LEU B 538
ALA B 640
 None
 1.06A 3uvvB-1ffvB:
undetectable		 3uvvB-1ffvB:
15.74
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3UWL_B_FOZB316_0
(THYMIDYLATE SYNTHASE)		 1ffv CUTL, MOLYBDOPROTEIN
OF CARBON MONOXIDE
DEHYDROGENASE
(Hydrogenophaga
pseudoflava) 		5 / 12 ILE B 622
LEU B 538
GLY B 539
ILE B 507
ALA B 513
 None
 0.89A 3uwlB-1ffvB:
0.8		 3uwlB-1ffvB:
18.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3W9T_C_W9TC1005_1
(HEMOLYTIC LECTIN
CEL-III)		 1ffv CUTL, MOLYBDOPROTEIN
OF CARBON MONOXIDE
DEHYDROGENASE
CUTS, IRON-SULFUR
PROTEIN OF CARBON
MONOXIDE
DEHYDROGENASE
(Hydrogenophaga
pseudoflava) 		3 / 3 ASP B  40
GLY A  37
TYR B  37
 None
 0.74A 3w9tC-1ffvB:
0.0		 3w9tC-1ffvB:
20.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3W9T_G_W9TG503_1
(HEMOLYTIC LECTIN
CEL-III)		 1ffv CUTL, MOLYBDOPROTEIN
OF CARBON MONOXIDE
DEHYDROGENASE
CUTS, IRON-SULFUR
PROTEIN OF CARBON
MONOXIDE
DEHYDROGENASE
(Hydrogenophaga
pseudoflava) 		3 / 3 ASP B  40
GLY A  37
TYR B  37
 None
 0.74A 3w9tG-1ffvB:
undetectable		 3w9tG-1ffvB:
20.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4C5L_C_UEGC300_1
(PHOSPHOMETHYLPYRIMID
INE KINASE)		 1ffv CUTS, IRON-SULFUR
PROTEIN OF CARBON
MONOXIDE
DEHYDROGENASE
(Hydrogenophaga
pseudoflava) 		5 / 10 GLY A 133
ALA A  49
GLY A  48
CYH A  42
CYH A  50
 None
None
FES  A1908 (-3.7A)
FES  A1908 (-2.3A)
FES  A1908 (-2.2A)
 1.25A 4c5lC-1ffvA:
undetectable		 4c5lC-1ffvA:
21.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4CTJ_C_SAMC1263_0
(NON-STRUCTURAL
PROTEIN 5)		 1ffv CUTS, IRON-SULFUR
PROTEIN OF CARBON
MONOXIDE
DEHYDROGENASE
CUTL, MOLYBDOPROTEIN
OF CARBON MONOXIDE
DEHYDROGENASE
(Hydrogenophaga
pseudoflava;
Hydrogenophaga
pseudoflava) 		5 / 12 GLY A  98
GLY B 695
GLY A 140
THR B 698
ILE B 693
 None
ARO  B 384 ( 3.9A)
None
None
None
 0.89A 4ctjC-1ffvA:
undetectable		 4ctjC-1ffvA:
21.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4CTK_A_SAMA1263_0
(POLYPROTEIN)		 1ffv CUTS, IRON-SULFUR
PROTEIN OF CARBON
MONOXIDE
DEHYDROGENASE
CUTL, MOLYBDOPROTEIN
OF CARBON MONOXIDE
DEHYDROGENASE
(Hydrogenophaga
pseudoflava;
Hydrogenophaga
pseudoflava) 		5 / 12 GLY A  98
GLY B 695
GLY A 140
THR B 698
ILE B 693
 None
ARO  B 384 ( 3.9A)
None
None
None
 0.90A 4ctkA-1ffvA:
undetectable		 4ctkA-1ffvA:
21.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4CTK_C_SAMC1263_0
(POLYPROTEIN)		 1ffv CUTS, IRON-SULFUR
PROTEIN OF CARBON
MONOXIDE
DEHYDROGENASE
CUTL, MOLYBDOPROTEIN
OF CARBON MONOXIDE
DEHYDROGENASE
(Hydrogenophaga
pseudoflava;
Hydrogenophaga
pseudoflava) 		5 / 12 GLY A  98
GLY B 695
GLY A 140
THR B 698
ILE B 693
 None
ARO  B 384 ( 3.9A)
None
None
None
 0.89A 4ctkC-1ffvA:
undetectable		 4ctkC-1ffvA:
21.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4DAJ_B_0HKB2000_2
(MUSCARINIC
ACETYLCHOLINE
RECEPTOR M3,
LYSOZYME)		 1ffv CUTS, IRON-SULFUR
PROTEIN OF CARBON
MONOXIDE
DEHYDROGENASE
(Hydrogenophaga
pseudoflava) 		3 / 3 ASN A 134
LEU A  80
PHE A 115
 None
 0.73A 4dajB-1ffvA:
0.0		 4dajB-1ffvA:
16.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4EAH_F_ACTF402_0
(ACTIN, ALPHA
SKELETAL MUSCLE)		 1ffv CUTL, MOLYBDOPROTEIN
OF CARBON MONOXIDE
DEHYDROGENASE
CUTM, FLAVOPROTEIN
OF CARBON MONOXIDE
DEHYDROGENASE
(Hydrogenophaga
pseudoflava;
Hydrogenophaga
pseudoflava) 		3 / 3 PHE B 726
ASP B 724
ARG C 188
 None
 0.67A 4eahF-1ffvB:
0.0		 4eahF-1ffvB:
19.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4EAH_G_ACTG401_0
(ACTIN, ALPHA
SKELETAL MUSCLE)		 1ffv CUTL, MOLYBDOPROTEIN
OF CARBON MONOXIDE
DEHYDROGENASE
CUTM, FLAVOPROTEIN
OF CARBON MONOXIDE
DEHYDROGENASE
(Hydrogenophaga
pseudoflava;
Hydrogenophaga
pseudoflava) 		3 / 3 PHE B 726
ASP B 724
ARG C 188
 None
 0.67A 4eahG-1ffvB:
0.0		 4eahG-1ffvB:
19.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4EB6_C_VLBC503_1
(TUBULIN BETA CHAIN
TUBULIN ALPHA CHAIN)		 1ffv CUTL, MOLYBDOPROTEIN
OF CARBON MONOXIDE
DEHYDROGENASE
(Hydrogenophaga
pseudoflava) 		5 / 12 PRO B 363
ASN B 418
ILE B 414
VAL B 400
ILE B 396
 None
 1.23A 4eb6B-1ffvB:
undetectable
4eb6C-1ffvB:
undetectable		 4eb6B-1ffvB:
19.59
4eb6C-1ffvB:
20.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4EYZ_A_CCSA109_0
(CELLULOSOME-RELATED
PROTEIN MODULE FROM
RUMINOCOCCUS
FLAVEFACIENS THAT
RESEMBLES
PAPAIN-LIKE CYSTEINE
PEPTIDASES)		 1ffv CUTL, MOLYBDOPROTEIN
OF CARBON MONOXIDE
DEHYDROGENASE
(Hydrogenophaga
pseudoflava) 		5 / 8 PHE B 649
VAL B 483
HIS B 354
ILE B 355
ALA B 183
 None
 1.05A 4eyzA-1ffvB:
0.0		 4eyzA-1ffvB:
15.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4EYZ_B_CCSB109_0
(CELLULOSOME-RELATED
PROTEIN MODULE FROM
RUMINOCOCCUS
FLAVEFACIENS THAT
RESEMBLES
PAPAIN-LIKE CYSTEINE
PEPTIDASES)		 1ffv CUTL, MOLYBDOPROTEIN
OF CARBON MONOXIDE
DEHYDROGENASE
(Hydrogenophaga
pseudoflava) 		5 / 8 PHE B 649
VAL B 483
HIS B 354
ILE B 355
ALA B 183
 None
 1.04A 4eyzB-1ffvB:
0.0		 4eyzB-1ffvB:
15.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4G2Z_A_ID8A711_1
(LACTOTRANSFERRIN)		 1ffv CUTL, MOLYBDOPROTEIN
OF CARBON MONOXIDE
DEHYDROGENASE
(Hydrogenophaga
pseudoflava) 		3 / 3 PRO B 749
TYR B 644
GLY B 571
 None
 0.68A 4g2zA-1ffvB:
undetectable		 4g2zA-1ffvB:
16.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4K6I_A_9RAA500_1
(RETINOIC ACID
RECEPTOR RXR-ALPHA)		 1ffv CUTL, MOLYBDOPROTEIN
OF CARBON MONOXIDE
DEHYDROGENASE
(Hydrogenophaga
pseudoflava) 		5 / 12 ILE B 574
ALA B 577
ALA B 578
ILE B 545
ALA B 640
 None
 0.95A 4k6iA-1ffvB:
undetectable		 4k6iA-1ffvB:
14.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4K6I_A_9RAA500_1
(RETINOIC ACID
RECEPTOR RXR-ALPHA)		 1ffv CUTL, MOLYBDOPROTEIN
OF CARBON MONOXIDE
DEHYDROGENASE
(Hydrogenophaga
pseudoflava) 		5 / 12 ILE B 574
ALA B 577
ALA B 578
LEU B 538
ALA B 640
 None
 1.01A 4k6iA-1ffvB:
undetectable		 4k6iA-1ffvB:
14.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KOS_A_4KOA201_1
(UNCHARACTERIZED
PROTEIN)		 1ffv CUTS, IRON-SULFUR
PROTEIN OF CARBON
MONOXIDE
DEHYDROGENASE
(Hydrogenophaga
pseudoflava) 		5 / 12 CYH A 104
PRO A 106
GLY A  48
ASN A 134
ILE A  40
 FES  A1907 (-2.2A)
None
FES  A1908 (-3.7A)
None
FES  A1908 ( 4.4A)
 1.45A 4kosA-1ffvA:
0.0		 4kosA-1ffvA:
24.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4M51_A_BEZA501_0
(AMIDOHYDROLASE
FAMILY PROTEIN)		 1ffv CUTM, FLAVOPROTEIN
OF CARBON MONOXIDE
DEHYDROGENASE
(Hydrogenophaga
pseudoflava) 		4 / 6 ILE C 101
ILE C 116
SER C 129
LEU C  94
 FAD  C1922 (-4.0A)
None
None
None
 0.99A 4m51A-1ffvC:
0.0		 4m51A-1ffvC:
22.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4NKV_A_AERA601_1
(STEROID
17-ALPHA-HYDROXYLASE
/17,20 LYASE)		 1ffv CUTL, MOLYBDOPROTEIN
OF CARBON MONOXIDE
DEHYDROGENASE
(Hydrogenophaga
pseudoflava) 		5 / 12 ILE B 689
ILE B 688
ARG B 683
GLY B  19
ALA B  20
 PCD  B1920 (-4.7A)
PCD  B1920 (-4.4A)
None
None
None
 0.95A 4nkvA-1ffvB:
undetectable		 4nkvA-1ffvB:
20.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4NKV_B_AERB601_2
(STEROID
17-ALPHA-HYDROXYLASE
/17,20 LYASE)		 1ffv CUTL, MOLYBDOPROTEIN
OF CARBON MONOXIDE
DEHYDROGENASE
(Hydrogenophaga
pseudoflava) 		4 / 5 ARG B 464
ASP B 773
GLU B 459
VAL B 451
 None
 1.46A 4nkvB-1ffvB:
0.0		 4nkvB-1ffvB:
20.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4OAE_A_CLMA208_0
(GNAT SUPERFAMILY
ACETYLTRANSFERASE
PA4794)		 1ffv CUTM, FLAVOPROTEIN
OF CARBON MONOXIDE
DEHYDROGENASE
(Hydrogenophaga
pseudoflava) 		4 / 4 ALA C 242
ALA C 245
ALA C 246
ALA C 249
 None
 0.12A 4oaeA-1ffvC:
0.0		 4oaeA-1ffvC:
21.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4P7N_A_GCSA702_1
(POLY-BETA-1,6-N-ACET
YL-D-GLUCOSAMINE
N-DEACETYLASE)		 1ffv CUTM, FLAVOPROTEIN
OF CARBON MONOXIDE
DEHYDROGENASE
(Hydrogenophaga
pseudoflava) 		3 / 3 ASP C 120
TYR C 157
TRP C 193
 None
None
FAD  C1922 (-3.7A)
 1.40A 4p7nA-1ffvC:
undetectable		 4p7nA-1ffvC:
22.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4PGF_B_ADNB502_2
(ADENOSYLHOMOCYSTEINA
SE)		 1ffv CUTL, MOLYBDOPROTEIN
OF CARBON MONOXIDE
DEHYDROGENASE
(Hydrogenophaga
pseudoflava) 		4 / 5 THR B 519
THR B 561
THR B 650
HIS B 748
 None
PCD  B1920 ( 4.3A)
None
None
 1.33A 4pgfB-1ffvB:
undetectable		 4pgfB-1ffvB:
20.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4PWD_A_NVPA901_1
(HIV-1 REVERSE
TRANSCRIPTASE, P66
SUBUNIT)		 1ffv CUTM, FLAVOPROTEIN
OF CARBON MONOXIDE
DEHYDROGENASE
CUTS, IRON-SULFUR
PROTEIN OF CARBON
MONOXIDE
DEHYDROGENASE
(Hydrogenophaga
pseudoflava) 		4 / 8 PRO C   3
LEU A  65
VAL A  19
LEU C  51
 None
 0.98A 4pwdA-1ffvC:
2.3		 4pwdA-1ffvC:
17.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4UUU_A_SAMA1546_0
(CYSTATHIONINE
BETA-SYNTHASE)		 1ffv CUTL, MOLYBDOPROTEIN
OF CARBON MONOXIDE
DEHYDROGENASE
(Hydrogenophaga
pseudoflava) 		5 / 11 LEU B 407
ASP B 401
HIS B 782
VAL B 200
ILE B 396
 None
 1.36A 4uuuA-1ffvB:
0.0
4uuuB-1ffvB:
0.0		 4uuuA-1ffvB:
10.53
4uuuB-1ffvB:
10.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4V1F_B_BQ1B1087_0
(F0F1 ATP SYNTHASE
SUBUNIT C)		 1ffv CUTM, FLAVOPROTEIN
OF CARBON MONOXIDE
DEHYDROGENASE
(Hydrogenophaga
pseudoflava) 		5 / 8 ALA C 249
ALA C 250
ILE C 253
ALA C 199
LEU C 224
 None
 1.27A 4v1fA-1ffvC:
undetectable
4v1fB-1ffvC:
undetectable		 4v1fA-1ffvC:
17.50
4v1fB-1ffvC:
17.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4V20_A_ACTA1444_0
(CELLOBIOHYDROLASE)		 1ffv CUTS, IRON-SULFUR
PROTEIN OF CARBON
MONOXIDE
DEHYDROGENASE
CUTL, MOLYBDOPROTEIN
OF CARBON MONOXIDE
DEHYDROGENASE
(Hydrogenophaga
pseudoflava;
Hydrogenophaga
pseudoflava) 		4 / 5 GLY A 102
THR A 105
HIS A  39
GLY B  33
 FES  A1907 (-4.3A)
None
None
None
 1.16A 4v20A-1ffvA:
0.0		 4v20A-1ffvA:
16.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4XJE_A_TOYA202_1
(AADB)		 1ffv CUTL, MOLYBDOPROTEIN
OF CARBON MONOXIDE
DEHYDROGENASE
(Hydrogenophaga
pseudoflava) 		4 / 8 ASP B 335
TYR B 205
ASP B 310
ASP B 145
 None
 0.95A 4xjeA-1ffvB:
undetectable		 4xjeA-1ffvB:
13.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4XZK_A_AG2A700_1
(PUTATIVE
NAD(+)--ARGININE
ADP-RIBOSYLTRANSFERA
SE VIS)		 1ffv CUTL, MOLYBDOPROTEIN
OF CARBON MONOXIDE
DEHYDROGENASE
(Hydrogenophaga
pseudoflava) 		4 / 7 SER B 386
SER B 564
GLU B 482
GLU B 757
 CSZ  B 385 ( 3.5A)
PCD  B1920 (-4.0A)
None
PCD  B1920 (-3.2A)
 1.12A 4xzkA-1ffvB:
undetectable		 4xzkA-1ffvB:
14.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ZF8_A_MYTA502_1
(BIFUNCTIONAL
P-450/NADPH-P450
REDUCTASE)		 1ffv CUTM, FLAVOPROTEIN
OF CARBON MONOXIDE
DEHYDROGENASE
(Hydrogenophaga
pseudoflava) 		4 / 6 VAL C 275
ILE C 251
ALA C 250
ALA C 232
 None
 0.71A 4zf8A-1ffvC:
0.0		 4zf8A-1ffvC:
20.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5B6I_A_ADNA302_1
(FLUORINASE)		 1ffv CUTL, MOLYBDOPROTEIN
OF CARBON MONOXIDE
DEHYDROGENASE
(Hydrogenophaga
pseudoflava) 		4 / 7 ASP B 436
THR B 650
PRO B 652
THR B 481
 None
 0.98A 5b6iA-1ffvB:
undetectable		 5b6iA-1ffvB:
17.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5CFS_A_TOYA203_1
(AAD(2''),GENTAMICIN
2''-NUCLEOTIDYLTRANS
FERASE,GENTAMICIN
RESISTANCE PROTEIN)		 1ffv CUTL, MOLYBDOPROTEIN
OF CARBON MONOXIDE
DEHYDROGENASE
(Hydrogenophaga
pseudoflava) 		4 / 8 ASP B 335
TYR B 205
ASP B 310
ASP B 145
 None
 0.84A 5cfsA-1ffvB:
0.0		 5cfsA-1ffvB:
13.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5CU6_A_ACTA403_0
(CASEIN KINASE II
SUBUNIT ALPHA)		 1ffv CUTL, MOLYBDOPROTEIN
OF CARBON MONOXIDE
DEHYDROGENASE
(Hydrogenophaga
pseudoflava) 		4 / 6 TYR B 530
ILE B 505
VAL B 547
ALA B 515
 None
 0.83A 5cu6A-1ffvB:
undetectable		 5cu6A-1ffvB:
17.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5DQF_A_CZEA613_1
(SERUM ALBUMIN)		 1ffv CUTM, FLAVOPROTEIN
OF CARBON MONOXIDE
DEHYDROGENASE
(Hydrogenophaga
pseudoflava) 		5 / 9 ALA C  17
LEU C  24
GLY C  22
LEU C  21
LEU C  30
 None
None
None
None
FAD  C1922 (-4.4A)
 1.21A 5dqfA-1ffvC:
2.7		 5dqfA-1ffvC:
19.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EC8_C_SAMC4000_0
(GENOME POLYPROTEIN)		 1ffv CUTS, IRON-SULFUR
PROTEIN OF CARBON
MONOXIDE
DEHYDROGENASE
CUTL, MOLYBDOPROTEIN
OF CARBON MONOXIDE
DEHYDROGENASE
(Hydrogenophaga
pseudoflava;
Hydrogenophaga
pseudoflava) 		5 / 12 GLY A  98
GLY B 695
GLY A 140
THR B 698
ILE B 693
 None
ARO  B 384 ( 3.9A)
None
None
None
 0.89A 5ec8C-1ffvA:
undetectable		 5ec8C-1ffvA:
21.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EHG_A_SAMA301_0
(RNA-DIRECTED RNA
POLYMERASE NS5)		 1ffv CUTS, IRON-SULFUR
PROTEIN OF CARBON
MONOXIDE
DEHYDROGENASE
CUTL, MOLYBDOPROTEIN
OF CARBON MONOXIDE
DEHYDROGENASE
(Hydrogenophaga
pseudoflava;
Hydrogenophaga
pseudoflava) 		5 / 12 GLY A  98
GLY B 695
GLY A 140
THR B 698
ILE B 693
 None
ARO  B 384 ( 3.9A)
None
None
None
 0.88A 5ehgA-1ffvA:
undetectable		 5ehgA-1ffvA:
21.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EHG_C_SAMC4001_0
(RNA-DIRECTED RNA
POLYMERASE NS5)		 1ffv CUTS, IRON-SULFUR
PROTEIN OF CARBON
MONOXIDE
DEHYDROGENASE
CUTL, MOLYBDOPROTEIN
OF CARBON MONOXIDE
DEHYDROGENASE
(Hydrogenophaga
pseudoflava;
Hydrogenophaga
pseudoflava) 		5 / 12 GLY A  98
GLY B 695
GLY A 140
THR B 698
ILE B 693
 None
ARO  B 384 ( 3.9A)
None
None
None
 0.88A 5ehgC-1ffvA:
undetectable		 5ehgC-1ffvA:
21.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EIF_C_SAMC4000_0
(GENOME POLYPROTEIN)		 1ffv CUTS, IRON-SULFUR
PROTEIN OF CARBON
MONOXIDE
DEHYDROGENASE
CUTL, MOLYBDOPROTEIN
OF CARBON MONOXIDE
DEHYDROGENASE
(Hydrogenophaga
pseudoflava;
Hydrogenophaga
pseudoflava) 		5 / 12 GLY A  98
GLY B 695
GLY A 140
THR B 698
ILE B 693
 None
ARO  B 384 ( 3.9A)
None
None
None
 0.90A 5eifC-1ffvA:
undetectable		 5eifC-1ffvA:
21.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EKX_B_SAMB4000_0
(NS5
METHYLTRANSFERASE)		 1ffv CUTS, IRON-SULFUR
PROTEIN OF CARBON
MONOXIDE
DEHYDROGENASE
CUTL, MOLYBDOPROTEIN
OF CARBON MONOXIDE
DEHYDROGENASE
(Hydrogenophaga
pseudoflava;
Hydrogenophaga
pseudoflava) 		5 / 12 GLY A  98
GLY B 695
GLY A 140
THR B 698
ILE B 693
 None
ARO  B 384 ( 3.9A)
None
None
None
 0.89A 5ekxB-1ffvA:
undetectable		 5ekxB-1ffvA:
21.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5G5H_C_ACTC1742_0
(PUTATIVE XANTHINE
DEHYDROGENASE YAGR
MOLYBDENUM-BINDING
SUBUNIT)		 1ffv CUTL, MOLYBDOPROTEIN
OF CARBON MONOXIDE
DEHYDROGENASE
(Hydrogenophaga
pseudoflava) 		4 / 5 ASP B 224
LYS B 227
THR B 231
ASP B 229
 None
 1.32A 5g5hC-1ffvB:
36.0		 5g5hC-1ffvB:
26.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5I6X_A_8PRA705_1
(SODIUM-DEPENDENT
SEROTONIN
TRANSPORTER)		 1ffv CUTM, FLAVOPROTEIN
OF CARBON MONOXIDE
DEHYDROGENASE
(Hydrogenophaga
pseudoflava) 		5 / 10 ALA C 117
ILE C 116
GLY C 151
PHE C 152
GLY C 119
 FAD  C1922 (-3.2A)
None
None
None
None
 1.17A 5i6xA-1ffvC:
2.2		 5i6xA-1ffvC:
19.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5I73_A_68PA701_1
(SODIUM-DEPENDENT
SEROTONIN
TRANSPORTER)		 1ffv CUTL, MOLYBDOPROTEIN
OF CARBON MONOXIDE
DEHYDROGENASE
(Hydrogenophaga
pseudoflava) 		5 / 12 ILE B 286
GLY B 228
GLY B 289
LEU B 288
GLY B 251
 None
 0.99A 5i73A-1ffvB:
0.0		 5i73A-1ffvB:
20.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5IGT_A_ERYA402_0
(MACROLIDE
2'-PHOSPHOTRANSFERAS
E)		 1ffv CUTL, MOLYBDOPROTEIN
OF CARBON MONOXIDE
DEHYDROGENASE
(Hydrogenophaga
pseudoflava) 		5 / 12 ILE B 520
VAL B 260
ALA B 221
GLY B 277
TYR B 275
 None
 1.03A 5igtA-1ffvB:
0.0		 5igtA-1ffvB:
17.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5IKM_A_SAMA311_0
(NS5 METHYL
TRANSFERASE)		 1ffv CUTS, IRON-SULFUR
PROTEIN OF CARBON
MONOXIDE
DEHYDROGENASE
CUTL, MOLYBDOPROTEIN
OF CARBON MONOXIDE
DEHYDROGENASE
(Hydrogenophaga
pseudoflava;
Hydrogenophaga
pseudoflava) 		5 / 12 GLY A  98
GLY B 695
GLY A 140
THR B 698
ILE B 693
 None
ARO  B 384 ( 3.9A)
None
None
None
 0.90A 5ikmA-1ffvA:
undetectable		 5ikmA-1ffvA:
22.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5IMS_A_ACTA708_0
(ACETOLACTATE
SYNTHASE CATALYTIC
SUBUNIT,
MITOCHONDRIAL)		 1ffv CUTS, IRON-SULFUR
PROTEIN OF CARBON
MONOXIDE
DEHYDROGENASE
CUTM, FLAVOPROTEIN
OF CARBON MONOXIDE
DEHYDROGENASE
(Hydrogenophaga
pseudoflava;
Hydrogenophaga
pseudoflava) 		3 / 3 GLY C  34
GLY C  33
GLN A  68
 FAD  C1922 (-3.2A)
FAD  C1922 (-3.3A)
None
 0.50A 5imsA-1ffvC:
undetectable		 5imsA-1ffvC:
18.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5IMS_B_ACTB713_0
(ACETOLACTATE
SYNTHASE CATALYTIC
SUBUNIT,
MITOCHONDRIAL)		 1ffv CUTL, MOLYBDOPROTEIN
OF CARBON MONOXIDE
DEHYDROGENASE
(Hydrogenophaga
pseudoflava) 		3 / 3 GLY B 266
GLN B 524
LYS B 271
 PCD  B1920 (-3.6A)
PCD  B1920 (-3.5A)
None
 0.99A 5imsB-1ffvB:
undetectable		 5imsB-1ffvB:
22.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5J7W_C_MTXC402_1
(THYMIDYLATE SYNTHASE)		 1ffv CUTL, MOLYBDOPROTEIN
OF CARBON MONOXIDE
DEHYDROGENASE
(Hydrogenophaga
pseudoflava) 		5 / 12 ILE B 622
LEU B 538
GLY B 539
ILE B 507
ALA B 513
 None
 0.84A 5j7wC-1ffvB:
0.8		 5j7wC-1ffvB:
18.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5J7W_D_MTXD402_1
(THYMIDYLATE SYNTHASE)		 1ffv CUTL, MOLYBDOPROTEIN
OF CARBON MONOXIDE
DEHYDROGENASE
(Hydrogenophaga
pseudoflava) 		5 / 12 ILE B 622
LEU B 538
GLY B 539
ILE B 507
ALA B 513
 None
 0.84A 5j7wD-1ffvB:
0.7		 5j7wD-1ffvB:
18.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5JI0_A_9CRA501_1
(RETINOIC ACID
RECEPTOR RXR-ALPHA)		 1ffv CUTL, MOLYBDOPROTEIN
OF CARBON MONOXIDE
DEHYDROGENASE
(Hydrogenophaga
pseudoflava) 		5 / 11 ILE B 117
GLN B 113
LEU B 103
ALA B 104
VAL B 292
 None
 1.19A 5ji0A-1ffvB:
undetectable		 5ji0A-1ffvB:
16.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5KQR_A_SAMA301_0
(METHYLTRANSFERASE)		 1ffv CUTS, IRON-SULFUR
PROTEIN OF CARBON
MONOXIDE
DEHYDROGENASE
CUTL, MOLYBDOPROTEIN
OF CARBON MONOXIDE
DEHYDROGENASE
(Hydrogenophaga
pseudoflava;
Hydrogenophaga
pseudoflava) 		5 / 12 GLY A  98
GLY B 695
GLY A 140
THR B 698
ILE B 693
 None
ARO  B 384 ( 3.9A)
None
None
None
 0.88A 5kqrA-1ffvA:
undetectable		 5kqrA-1ffvA:
22.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5KQS_A_SAMA307_0
(GENOME POLYPROTEIN)		 1ffv CUTS, IRON-SULFUR
PROTEIN OF CARBON
MONOXIDE
DEHYDROGENASE
CUTL, MOLYBDOPROTEIN
OF CARBON MONOXIDE
DEHYDROGENASE
(Hydrogenophaga
pseudoflava;
Hydrogenophaga
pseudoflava) 		5 / 12 GLY A  98
GLY B 695
GLY A 140
THR B 698
ILE B 693
 None
ARO  B 384 ( 3.9A)
None
None
None
 0.88A 5kqsA-1ffvA:
undetectable		 5kqsA-1ffvA:
22.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5M5B_A_SAMA1001_0
(NS5
METHYLTRANSFERASE)		 1ffv CUTS, IRON-SULFUR
PROTEIN OF CARBON
MONOXIDE
DEHYDROGENASE
CUTL, MOLYBDOPROTEIN
OF CARBON MONOXIDE
DEHYDROGENASE
(Hydrogenophaga
pseudoflava;
Hydrogenophaga
pseudoflava) 		5 / 12 GLY A  98
GLY B 695
GLY A 140
THR B 698
ILE B 693
 None
ARO  B 384 ( 3.9A)
None
None
None
 0.89A 5m5bA-1ffvA:
undetectable		 5m5bA-1ffvA:
22.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5N9X_A_THRA601_0
(ADENYLATION DOMAIN)		 1ffv CUTL, MOLYBDOPROTEIN
OF CARBON MONOXIDE
DEHYDROGENASE
(Hydrogenophaga
pseudoflava) 		4 / 7 ASP B  27
PHE B  30
GLY B 523
GLY B 525
 None
None
PCD  B1920 (-3.6A)
PCD  B1920 ( 4.2A)
 1.02A 5n9xA-1ffvB:
undetectable		 5n9xA-1ffvB:
22.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5NJV_A_SAMA301_0
(NS5)		 1ffv CUTS, IRON-SULFUR
PROTEIN OF CARBON
MONOXIDE
DEHYDROGENASE
CUTL, MOLYBDOPROTEIN
OF CARBON MONOXIDE
DEHYDROGENASE
(Hydrogenophaga
pseudoflava;
Hydrogenophaga
pseudoflava) 		5 / 12 GLY A  98
GLY B 695
GLY A 140
THR B 698
ILE B 693
 None
ARO  B 384 ( 3.9A)
None
None
None
 0.87A 5njvA-1ffvA:
undetectable		 5njvA-1ffvA:
22.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5NJV_B_SAMB301_0
(NS5)		 1ffv CUTS, IRON-SULFUR
PROTEIN OF CARBON
MONOXIDE
DEHYDROGENASE
CUTL, MOLYBDOPROTEIN
OF CARBON MONOXIDE
DEHYDROGENASE
(Hydrogenophaga
pseudoflava;
Hydrogenophaga
pseudoflava) 		5 / 12 GLY A  98
GLY B 695
GLY A 140
THR B 698
ILE B 693
 None
ARO  B 384 ( 3.9A)
None
None
None
 0.86A 5njvB-1ffvA:
undetectable		 5njvB-1ffvA:
22.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5NJV_D_SAMD301_0
(NS5)		 1ffv CUTS, IRON-SULFUR
PROTEIN OF CARBON
MONOXIDE
DEHYDROGENASE
CUTL, MOLYBDOPROTEIN
OF CARBON MONOXIDE
DEHYDROGENASE
(Hydrogenophaga
pseudoflava;
Hydrogenophaga
pseudoflava) 		5 / 12 GLY A  98
GLY B 695
GLY A 140
THR B 698
ILE B 693
 None
ARO  B 384 ( 3.9A)
None
None
None
 0.91A 5njvD-1ffvA:
undetectable		 5njvD-1ffvA:
22.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5OEX_B_CUB602_0
(THIOCYANATE
DEHYDROGENASE)		 1ffv CUTL, MOLYBDOPROTEIN
OF CARBON MONOXIDE
DEHYDROGENASE
(Hydrogenophaga
pseudoflava) 		3 / 3 LYS B 107
HIS B 109
HIS B  58
 None
 1.39A 5oexB-1ffvB:
0.0		 5oexB-1ffvB:
20.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5OEX_C_CUC603_0
(THIOCYANATE
DEHYDROGENASE)		 1ffv CUTL, MOLYBDOPROTEIN
OF CARBON MONOXIDE
DEHYDROGENASE
(Hydrogenophaga
pseudoflava) 		3 / 3 LYS B 107
HIS B 109
HIS B  58
 None
 1.41A 5oexC-1ffvB:
0.0		 5oexC-1ffvB:
20.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5OEX_D_CUD603_0
(THIOCYANATE
DEHYDROGENASE)		 1ffv CUTL, MOLYBDOPROTEIN
OF CARBON MONOXIDE
DEHYDROGENASE
(Hydrogenophaga
pseudoflava) 		3 / 3 LYS B 107
HIS B 109
HIS B  58
 None
 1.41A 5oexD-1ffvB:
0.0		 5oexD-1ffvB:
20.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5OG9_A_TESA503_1
(-)		 1ffv CUTL, MOLYBDOPROTEIN
OF CARBON MONOXIDE
DEHYDROGENASE
CUTM, FLAVOPROTEIN
OF CARBON MONOXIDE
DEHYDROGENASE
CUTS, IRON-SULFUR
PROTEIN OF CARBON
MONOXIDE
DEHYDROGENASE
(Hydrogenophaga
pseudoflava) 		5 / 9 LEU B 722
VAL B 299
ILE A  40
LEU B 214
MET C   1
 None
None
FES  A1908 ( 4.4A)
FES  A1907 ( 4.3A)
None
 1.36A 5og9A-1ffvB:
0.0		 5og9A-1ffvB:
19.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VEU_B_RITB602_1
(CYTOCHROME P450 3A5)		 1ffv CUTL, MOLYBDOPROTEIN
OF CARBON MONOXIDE
DEHYDROGENASE
(Hydrogenophaga
pseudoflava) 		5 / 12 ILE B 534
ALA B 578
ALA B 585
ILE B 588
GLY B 637
 None
 0.87A 5veuB-1ffvB:
0.0		 5veuB-1ffvB:
21.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5WZ1_B_SAMB601_0
(NS5
METHYLTRANSFERASE)		 1ffv CUTS, IRON-SULFUR
PROTEIN OF CARBON
MONOXIDE
DEHYDROGENASE
CUTL, MOLYBDOPROTEIN
OF CARBON MONOXIDE
DEHYDROGENASE
(Hydrogenophaga
pseudoflava;
Hydrogenophaga
pseudoflava) 		5 / 12 GLY A  98
GLY B 695
GLY A 140
THR B 698
ILE B 693
 None
ARO  B 384 ( 3.9A)
None
None
None
 0.87A 5wz1B-1ffvA:
undetectable		 5wz1B-1ffvA:
22.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5WZ2_A_SAMA601_0
(NS5 MTASE)		 1ffv CUTS, IRON-SULFUR
PROTEIN OF CARBON
MONOXIDE
DEHYDROGENASE
CUTL, MOLYBDOPROTEIN
OF CARBON MONOXIDE
DEHYDROGENASE
(Hydrogenophaga
pseudoflava;
Hydrogenophaga
pseudoflava) 		5 / 12 GLY A  98
GLY B 695
GLY A 140
THR B 698
ILE B 693
 None
ARO  B 384 ( 3.9A)
None
None
None
 0.88A 5wz2A-1ffvA:
undetectable		 5wz2A-1ffvA:
22.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5WZ2_C_SAMC601_0
(NS5 MTASE)		 1ffv CUTS, IRON-SULFUR
PROTEIN OF CARBON
MONOXIDE
DEHYDROGENASE
CUTL, MOLYBDOPROTEIN
OF CARBON MONOXIDE
DEHYDROGENASE
(Hydrogenophaga
pseudoflava;
Hydrogenophaga
pseudoflava) 		5 / 12 GLY A  98
GLY B 695
GLY A 140
THR B 698
ILE B 693
 None
ARO  B 384 ( 3.9A)
None
None
None
 0.90A 5wz2C-1ffvA:
undetectable		 5wz2C-1ffvA:
22.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6A5Z_D_9CRD501_0
(RETINOIC ACID
RECEPTOR RXR-ALPHA)		 1ffv CUTL, MOLYBDOPROTEIN
OF CARBON MONOXIDE
DEHYDROGENASE
(Hydrogenophaga
pseudoflava) 		5 / 12 ILE B 574
ALA B 577
ALA B 578
ILE B 545
ALA B 640
 None
 1.01A 6a5zD-1ffvB:
undetectable		 6a5zD-1ffvB:
7.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B5V_A_ECLA1001_1
(TRANSIENT RECEPTOR
POTENTIAL CATION
CHANNEL SUBFAMILY V
MEMBER 5)		 1ffv CUTL, MOLYBDOPROTEIN
OF CARBON MONOXIDE
DEHYDROGENASE
(Hydrogenophaga
pseudoflava) 		4 / 7 ILE B 655
PHE B 674
ILE B 414
ALA B 770
 None
 0.76A 6b5vA-1ffvB:
0.0
6b5vC-1ffvB:
undetectable		 6b5vA-1ffvB:
6.89
6b5vC-1ffvB:
6.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B5V_B_ECLB1001_1
(TRANSIENT RECEPTOR
POTENTIAL CATION
CHANNEL SUBFAMILY V
MEMBER 5)		 1ffv CUTL, MOLYBDOPROTEIN
OF CARBON MONOXIDE
DEHYDROGENASE
(Hydrogenophaga
pseudoflava) 		4 / 7 ALA B 770
ILE B 655
PHE B 674
ILE B 414
 None
 0.75A 6b5vA-1ffvB:
0.0
6b5vB-1ffvB:
0.0		 6b5vA-1ffvB:
6.89
6b5vB-1ffvB:
6.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B5V_C_ECLC1001_1
(TRANSIENT RECEPTOR
POTENTIAL CATION
CHANNEL SUBFAMILY V
MEMBER 5)		 1ffv CUTL, MOLYBDOPROTEIN
OF CARBON MONOXIDE
DEHYDROGENASE
(Hydrogenophaga
pseudoflava) 		4 / 7 ILE B 655
PHE B 674
ILE B 414
ALA B 770
 None
 0.77A 6b5vC-1ffvB:
undetectable
6b5vD-1ffvB:
0.0		 6b5vC-1ffvB:
6.89
6b5vD-1ffvB:
6.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B5V_D_ECLD1001_1
(TRANSIENT RECEPTOR
POTENTIAL CATION
CHANNEL SUBFAMILY V
MEMBER 5)		 1ffv CUTL, MOLYBDOPROTEIN
OF CARBON MONOXIDE
DEHYDROGENASE
(Hydrogenophaga
pseudoflava) 		4 / 7 ALA B 770
ILE B 655
PHE B 674
ILE B 414
 None
 0.76A 6b5vB-1ffvB:
undetectable
6b5vD-1ffvB:
0.0		 6b5vB-1ffvB:
6.89
6b5vD-1ffvB:
6.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B89_A_NOVA403_2
(LIPOPOLYSACCHARIDE
EXPORT SYSTEM
ATP-BINDING PROTEIN
LPTB)		 1ffv CUTL, MOLYBDOPROTEIN
OF CARBON MONOXIDE
DEHYDROGENASE
(Hydrogenophaga
pseudoflava) 		4 / 6 PHE B 387
ARG B 388
LEU B 352
ALA B 486
 None
 0.81A 6b89B-1ffvB:
undetectable		 6b89B-1ffvB:
9.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B89_B_NOVB403_1
(LIPOPOLYSACCHARIDE
EXPORT SYSTEM
ATP-BINDING PROTEIN
LPTB)		 1ffv CUTL, MOLYBDOPROTEIN
OF CARBON MONOXIDE
DEHYDROGENASE
(Hydrogenophaga
pseudoflava) 		4 / 7 PHE B 387
ARG B 388
LEU B 352
ALA B 486
 None
 0.90A 6b89A-1ffvB:
0.0		 6b89A-1ffvB:
9.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6C79_A_CE3A301_1
(BETA-LACTAMASE
TOHO-1)		 1ffv CUTM, FLAVOPROTEIN
OF CARBON MONOXIDE
DEHYDROGENASE
CUTS, IRON-SULFUR
PROTEIN OF CARBON
MONOXIDE
DEHYDROGENASE
(Hydrogenophaga
pseudoflava) 		5 / 12 ASN C 108
ASN C  79
THR C 190
GLY A 130
ASN A 134
 None
 1.15A 6c79A-1ffvC:
undetectable		 6c79A-1ffvC:
14.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6DJZ_B_GMJB301_1
(SIGMA NON-OPIOID
INTRACELLULAR
RECEPTOR 1)		 1ffv CUTL, MOLYBDOPROTEIN
OF CARBON MONOXIDE
DEHYDROGENASE
(Hydrogenophaga
pseudoflava) 		4 / 6 TYR B 394
ASP B 401
VAL B 402
ALA B 704
 None
 1.20A 6djzB-1ffvB:
0.0		 6djzB-1ffvB:
13.34
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6DWN_A_AQ4A602_0
(CYTOCHROME P450 1A1)		 1ffv CUTM, FLAVOPROTEIN
OF CARBON MONOXIDE
DEHYDROGENASE
(Hydrogenophaga
pseudoflava) 		5 / 12 ASN C  55
LEU C  31
ASP C 115
GLY C 110
ILE C 170
 None
None
FAD  C1922 (-2.9A)
FAD  C1922 (-3.7A)
None
 1.16A 6dwnA-1ffvC:
undetectable		 6dwnA-1ffvC:
15.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6DWN_A_AQ4A602_0
(CYTOCHROME P450 1A1)		 1ffv CUTM, FLAVOPROTEIN
OF CARBON MONOXIDE
DEHYDROGENASE
(Hydrogenophaga
pseudoflava) 		5 / 12 PHE C 153
LEU C 224
ASP C 115
GLY C 119
ILE C 170
 None
None
FAD  C1922 (-2.9A)
None
None
 1.34A 6dwnA-1ffvC:
undetectable		 6dwnA-1ffvC:
15.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6DWN_C_AQ4C602_0
(CYTOCHROME P450 1A1)		 1ffv CUTM, FLAVOPROTEIN
OF CARBON MONOXIDE
DEHYDROGENASE
(Hydrogenophaga
pseudoflava) 		5 / 12 ASN C  55
LEU C  31
ASP C 115
GLY C 110
ILE C 170
 None
None
FAD  C1922 (-2.9A)
FAD  C1922 (-3.7A)
None
 0.99A 6dwnC-1ffvC:
0.0		 6dwnC-1ffvC:
15.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6EKZ_A_SNPA413_0
(AROMATIC
PEROXYGENASE)		 1ffv CUTL, MOLYBDOPROTEIN
OF CARBON MONOXIDE
DEHYDROGENASE
(Hydrogenophaga
pseudoflava) 		4 / 7 GLN B 522
GLY B 754
SER B 566
VAL B 484
 PCD  B1920 (-4.2A)
PCD  B1920 (-3.6A)
PCD  B1920 (-2.7A)
None
 0.71A 6ekzA-1ffvB:
0.0		 6ekzA-1ffvB:
7.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6EKZ_A_SNPA413_0
(AROMATIC
PEROXYGENASE)		 1ffv CUTL, MOLYBDOPROTEIN
OF CARBON MONOXIDE
DEHYDROGENASE
(Hydrogenophaga
pseudoflava) 		4 / 7 GLY B 487
PHE B 649
GLY B 485
VAL B 569
 None
 0.82A 6ekzA-1ffvB:
0.0		 6ekzA-1ffvB:
7.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6H1L_B_FJQB501_0
(BIFUNCTIONAL
CYTOCHROME
P450/NADPH--P450
REDUCTASE)		 1ffv CUTL, MOLYBDOPROTEIN
OF CARBON MONOXIDE
DEHYDROGENASE
(Hydrogenophaga
pseudoflava) 		5 / 11 VAL B 372
VAL B 143
THR B 374
ALA B 154
LEU B 150
 None
 1.23A 6h1lB-1ffvB:
0.0		 6h1lB-1ffvB:
19.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6MXT_A_K5YA1401_0
(ENDOLYSIN, BETA-2
ADRENERGIC RECEPTOR
CHIMERA)		 1ffv CUTL, MOLYBDOPROTEIN
OF CARBON MONOXIDE
DEHYDROGENASE
(Hydrogenophaga
pseudoflava) 		5 / 12 VAL B 755
ASP B 739
PHE B 480
TYR B 656
ILE B 655
 PCD  B1920 (-4.1A)
None
None
None
None
 1.35A 6mxtA-1ffvB:
0.0		 6mxtA-1ffvB:
19.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6QXS_D_FOZD403_0
(THYMIDYLATE SYNTHASE)		 1ffv CUTL, MOLYBDOPROTEIN
OF CARBON MONOXIDE
DEHYDROGENASE
(Hydrogenophaga
pseudoflava) 		5 / 12 ILE B 622
LEU B 538
GLY B 539
ILE B 507
ALA B 513
 None
 0.79A 6qxsD-1ffvB:
0.6		 6qxsD-1ffvB:
18.71