SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '1ffw'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1NP1_A_HSMA303_1
(NITROPHORIN 1)		 1ffw CHEMOTAXIS PROTEIN
CHEA
(Escherichia
coli) 		4 / 5 GLU B 177
LEU B 175
LEU B 174
LEU B 179
 None
 1.15A 1np1A-1ffwB:
0.0		 1np1A-1ffwB:
21.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2QK8_A_MTXA200_1
(DIHYDROFOLATE
REDUCTASE)		 1ffw CHEMOTAXIS PROTEIN
CHEA
(Escherichia
coli) 		5 / 12 ALA B 210
LEU B 182
ILE B 162
LEU B 199
PRO B 200
 None
 1.22A 2qk8A-1ffwB:
undetectable		 2qk8A-1ffwB:
21.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3TGV_B_BEZB160_0
(HEME-BINDING PROTEIN
HUTZ)		 1ffw CHEMOTAXIS PROTEIN
CHEA
(Escherichia
coli) 		4 / 4 LEU B 182
GLY B 180
LEU B 179
GLU B 178
 None
 1.10A 3tgvB-1ffwB:
undetectable		 3tgvB-1ffwB:
20.65