SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '1fh5'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1RG1_A_SPMA999_1
(TYROSYL-DNA
PHOSPHODIESTERASE 1)		 1fh5 MONOCLONAL ANTIBODY
MAK33
(Homo
sapiens) 		3 / 3 TRP H 190
VAL H 213
PRO H 214
 None
 0.90A 1rg1A-1fh5H:
0.0		 1rg1A-1fh5H:
19.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1RH0_A_SPMA999_1
(TYROSYL-DNA
PHOSPHODIESTERASE 1)		 1fh5 MONOCLONAL ANTIBODY
MAK33
(Homo
sapiens) 		3 / 3 TRP H 190
VAL H 213
PRO H 214
 None
 0.90A 1rh0A-1fh5H:
0.0		 1rh0A-1fh5H:
19.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3G1U_B_ADNB438_2
(ADENOSYLHOMOCYSTEINA
SE)		 1fh5 MONOCLONAL ANTIBODY
MAK33
(Homo
sapiens) 		3 / 3 THR H 117
GLU H 150
HIS H 201
 None
 0.83A 3g1uB-1fh5H:
undetectable		 3g1uB-1fh5H:
21.03
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3KDM_B_TESB226_1
(IMMUNOGLOBULIN LIGHT
CHAIN
IMMUNOGLOBULIN HEAVY
CHAIN)		 1fh5 MONOCLONAL ANTIBODY
MAK33
(Homo
sapiens) 		5 / 9 TRP H  44
TYR H  56
ASP H  96
TYR H  30
MET H 107
 None
 1.37A 3kdmA-1fh5H:
14.9
3kdmB-1fh5H:
23.2		 3kdmA-1fh5H:
30.36
3kdmB-1fh5H:
67.28
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3KDM_H_TESH226_1
(IMMUNOGLOBULIN HEAVY
CHAIN
IMMUNOGLOBULIN LIGHT
CHAIN)		 1fh5 MONOCLONAL ANTIBODY
MAK33
(Homo
sapiens) 		5 / 9 TRP H  44
TYR H  56
ASP H  96
TYR H  30
MET H 107
 None
 1.49A 3kdmH-1fh5H:
23.3
3kdmL-1fh5H:
14.8		 3kdmH-1fh5H:
67.28
3kdmL-1fh5H:
30.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5JSD_A_1GNA607_1
(PHIAB6 TAILSPIKE)		 1fh5 MONOCLONAL ANTIBODY
MAK33
(Homo
sapiens) 		3 / 3 THR H  25
SER H  28
TYR H  29
 None
 0.88A 5jsdA-1fh5H:
2.6		 5jsdA-1fh5H:
15.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5JSD_B_1GNB618_1
(PHIAB6 TAILSPIKE)		 1fh5 MONOCLONAL ANTIBODY
MAK33
(Homo
sapiens) 		3 / 3 THR H  25
SER H  28
TYR H  29
 None
 0.88A 5jsdB-1fh5H:
0.0		 5jsdB-1fh5H:
15.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5JSD_C_1GNC608_1
(PHIAB6 TAILSPIKE)		 1fh5 MONOCLONAL ANTIBODY
MAK33
(Homo
sapiens) 		3 / 3 THR H  25
SER H  28
TYR H  29
 None
 0.87A 5jsdC-1fh5H:
0.0		 5jsdC-1fh5H:
15.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5L8D_B_ACTB601_0
(NICKEL-BINDING
PERIPLASMIC PROTEIN)		 1fh5 MONOCLONAL ANTIBODY
MAK33
(Homo
sapiens) 		3 / 3 THR H  88
PRO H  38
ASP H  39
 None
 0.92A 5l8dB-1fh5H:
undetectable		 5l8dB-1fh5H:
17.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5MWU_B_ACTB601_0
(NICKEL-BINDING
PERIPLASMIC PROTEIN)		 1fh5 MONOCLONAL ANTIBODY
MAK33
(Homo
sapiens) 		3 / 3 THR H  88
PRO H  38
ASP H  39
 None
 0.92A 5mwuB-1fh5H:
undetectable		 5mwuB-1fh5H:
17.50