SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '1fhf'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1AEG_A_4APA296_1
(CYTOCHROME C
PEROXIDASE)		 1fhf SEED COAT PEROXIDASE
(Glycine
max) 		4 / 8 HIS A 169
GLY A 172
LEU A 243
ASP A 246
 HEM  A 350 (-3.5A)
HEM  A 350 (-3.5A)
None
None
 0.45A 1aegA-1fhfA:
23.9		 1aegA-1fhfA:
22.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1CBR_A_REAA200_1
(CELLULAR RETINOIC
ACID BINDING PROTEIN
TYPE I)		 1fhf SEED COAT PEROXIDASE
(Glycine
max) 		5 / 12 LEU A  36
ALA A  34
PRO A 225
ARG A  31
LEU A 242
 None
HEM  A 350 (-3.5A)
None
HEM  A 350 (-3.9A)
None
 1.26A 1cbrA-1fhfA:
undetectable		 1cbrA-1fhfA:
19.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1CBR_B_REAB200_1
(CELLULAR RETINOIC
ACID BINDING PROTEIN
TYPE I)		 1fhf SEED COAT PEROXIDASE
(Glycine
max) 		5 / 12 LEU A  36
ALA A  34
PRO A 225
ARG A  31
LEU A 242
 None
HEM  A 350 (-3.5A)
None
HEM  A 350 (-3.9A)
None
 1.26A 1cbrB-1fhfA:
undetectable		 1cbrB-1fhfA:
19.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2PLW_A_SAMA203_1
(RIBOSOMAL RNA
METHYLTRANSFERASE,
PUTATIVE)		 1fhf SEED COAT PEROXIDASE
(Glycine
max) 		3 / 3 SER A  35
ASP A 226
ASP A  29
 HEM  A 350 (-2.7A)
None
None
 0.80A 2plwA-1fhfA:
undetectable		 2plwA-1fhfA:
19.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2XFF_A_QPSA600_1
(BETA-AMYLASE)		 1fhf SEED COAT PEROXIDASE
(Glycine
max) 		5 / 12 ALA A 134
GLU A  64
GLN A 155
SER A  52
GLY A  51
 None
CA  A 501 ( 4.3A)
None
CA  A 501 (-2.3A)
None
 1.24A 2xffA-1fhfA:
undetectable		 2xffA-1fhfA:
21.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2Y05_A_RALA802_1
(PROSTAGLANDIN
REDUCTASE 1)		 1fhf SEED COAT PEROXIDASE
(Glycine
max) 		4 / 7 VAL A 261
TYR A 233
ASN A 235
GLY A 241
 None
 0.69A 2y05A-1fhfA:
undetectable
2y05B-1fhfA:
undetectable		 2y05A-1fhfA:
23.90
2y05B-1fhfA:
23.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ADX_B_IMNB3_1
(PEROXISOME
PROLIFERATOR-ACTIVAT
ED RECEPTOR GAMMA)		 1fhf SEED COAT PEROXIDASE
(Glycine
max) 		5 / 12 LEU A 242
ARG A 182
LEU A 201
LEU A 204
ILE A 180
 None
 0.82A 3adxB-1fhfA:
0.5		 3adxB-1fhfA:
22.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3AOC_C_ERYC3402_1
(ACRIFLAVINE
RESISTANCE PROTEIN B)		 1fhf SEED COAT PEROXIDASE
(Glycine
max) 		3 / 3 THR A  10
SER A  96
LYS A  84
 None
 1.21A 3aocC-1fhfA:
undetectable		 3aocC-1fhfA:
16.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3B9L_A_AZZA1010_1
(SERUM ALBUMIN)		 1fhf SEED COAT PEROXIDASE
(Glycine
max) 		4 / 8 LEU A  36
PHE A 228
ARG A  38
GLY A 168
 None
None
HEM  A 350 (-4.1A)
HEM  A 350 ( 4.3A)
 0.95A 3b9lA-1fhfA:
0.8		 3b9lA-1fhfA:
17.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3PGH_B_FLPB701_1
(CYCLOOXYGENASE-2)		 1fhf SEED COAT PEROXIDASE
(Glycine
max) 		5 / 11 VAL A 287
LEU A 288
LEU A   2
GLY A  51
ALA A  98
 None
 1.13A 3pghB-1fhfA:
undetectable		 3pghB-1fhfA:
19.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3SO9_A_017A100_1
(HIV-1 PROTEASE)		 1fhf SEED COAT PEROXIDASE
(Glycine
max) 		5 / 8 GLY A  51
ALA A  98
ASP A  99
GLY A 283
ILE A 285
 None
 1.41A 3so9A-1fhfA:
undetectable		 3so9A-1fhfA:
14.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4BLV_A_SAMA1281_0
(RIBOSOMAL RNA LARGE
SUBUNIT
METHYLTRANSFERASE J)		 1fhf SEED COAT PEROXIDASE
(Glycine
max) 		5 / 12 LEU A 101
GLY A 112
LEU A  39
HIS A  40
GLY A  76
 None
 0.99A 4blvA-1fhfA:
undetectable		 4blvA-1fhfA:
21.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4CX7_B_H4BB600_1
(NITRIC OXIDE
SYNTHASE, INDUCIBLE)		 1fhf SEED COAT PEROXIDASE
(Glycine
max) 		4 / 8 HIS A  40
GLU A 106
ARG A 123
ILE A 280
 None
 1.32A 4cx7A-1fhfA:
0.0
4cx7B-1fhfA:
0.1		 4cx7A-1fhfA:
20.27
4cx7B-1fhfA:
20.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4M7T_A_SAMA503_0
(BTRN)		 1fhf SEED COAT PEROXIDASE
(Glycine
max) 		5 / 11 TYR A 200
HIS A 169
TYR A 232
THR A 218
LEU A 196
 None
HEM  A 350 (-3.5A)
None
None
None
 1.34A 4m7tA-1fhfA:
0.0		 4m7tA-1fhfA:
21.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4O4D_A_ACTA406_0
(INOSITOL
HEXAKISPHOSPHATE
KINASE)		 1fhf SEED COAT PEROXIDASE
(Glycine
max) 		4 / 7 ASP A 221
THR A 224
ARG A 231
SER A 234
 CA  A 502 (-3.5A)
CA  A 502 (-3.5A)
None
None
 1.44A 4o4dA-1fhfA:
0.0		 4o4dA-1fhfA:
19.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4RS0_A_IBPA706_1
(PROSTAGLANDIN G/H
SYNTHASE 2)		 1fhf SEED COAT PEROXIDASE
(Glycine
max) 		5 / 9 VAL A 287
LEU A 288
LEU A   2
GLY A  51
ALA A  98
 None
 1.10A 4rs0A-1fhfA:
undetectable		 4rs0A-1fhfA:
19.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5L6E_A_SAMA601_1
(N6-ADENOSINE-METHYLT
RANSFERASE 70 KDA
SUBUNIT)		 1fhf SEED COAT PEROXIDASE
(Glycine
max) 		4 / 6 ASP A 125
ASN A 303
ASN A 300
GLN A 298
 None
 1.25A 5l6eA-1fhfA:
undetectable		 5l6eA-1fhfA:
20.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5TIW_A_OAQA302_0
(SULFOTRANSFERASE)		 1fhf SEED COAT PEROXIDASE
(Glycine
max) 		5 / 12 ILE A  74
LEU A  68
VAL A  46
LEU A  39
LEU A 101
 None
TRS  A2001 ( 4.7A)
CA  A 501 (-4.8A)
None
None
 1.10A 5tiwA-1fhfA:
undetectable		 5tiwA-1fhfA:
20.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6EXI_A_ADNA502_1
(ADENOSYLHOMOCYSTEINA
SE)		 1fhf SEED COAT PEROXIDASE
(Glycine
max) 		3 / 3 LEU A 183
ASN A 219
LEU A 243
 None
 0.70A 6exiA-1fhfA:
undetectable		 6exiA-1fhfA:
12.79