SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '1fhq'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1OSV_B_CHCB201_1
(BILE ACID RECEPTOR)		 1fhq PROTEIN KINASE SPK1
(Saccharomyces
cerevisiae) 		5 / 12 LEU A 618
PHE A 601
ILE A 678
PHE A 692
ILE A 613
 None
 1.39A 1osvB-1fhqA:
undetectable		 1osvB-1fhqA:
18.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2DU8_A_BEZA352_0
(D-AMINO-ACID OXIDASE)		 1fhq PROTEIN KINASE SPK1
(Saccharomyces
cerevisiae) 		4 / 6 LEU A 672
TYR A 649
ILE A 625
GLY A 691
 None
 0.90A 2du8A-1fhqA:
undetectable		 2du8A-1fhqA:
19.01
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3QPK_A_CUA601_0
(LACCASE-1)		 1fhq PROTEIN KINASE SPK1
(Saccharomyces
cerevisiae) 		4 / 5 HIS A 651
CYH A 623
ILE A 680
HIS A 622
 None
 1.30A 3qpkA-1fhqA:
undetectable		 3qpkA-1fhqA:
14.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3QPK_B_CUB601_0
(LACCASE-1)		 1fhq PROTEIN KINASE SPK1
(Saccharomyces
cerevisiae) 		4 / 4 HIS A 651
CYH A 623
ILE A 680
HIS A 622
 None
 1.28A 3qpkB-1fhqA:
undetectable		 3qpkB-1fhqA:
14.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3R0L_D_ACTD127_0
(PHOSPHOLIPASE A2 CB)		 1fhq PROTEIN KINASE SPK1
(Saccharomyces
cerevisiae) 		4 / 5 PHE A 692
ILE A 690
GLY A 604
CYH A 623
 None
 1.35A 3r0lD-1fhqA:
undetectable		 3r0lD-1fhqA:
19.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4UBE_A_2FAA401_1
(ADENOSINE KINASE)		 1fhq PROTEIN KINASE SPK1
(Saccharomyces
cerevisiae) 		5 / 12 ASP A 646
GLY A 706
GLY A 708
ASN A 704
GLN A 711
 None
 1.30A 4ubeA-1fhqA:
undetectable		 4ubeA-1fhqA:
16.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5G08_A_Z80A1187_1
(FREQUENIN 2)		 1fhq PROTEIN KINASE SPK1
(Saccharomyces
cerevisiae) 		4 / 6 ILE A 625
TYR A 649
PHE A 624
PHE A 692
 None
 1.32A 5g08A-1fhqA:
undetectable		 5g08A-1fhqA:
21.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5MEJ_A_CUA504_0
(LACCASE 2)		 1fhq PROTEIN KINASE SPK1
(Saccharomyces
cerevisiae) 		4 / 4 HIS A 651
CYH A 623
ILE A 680
HIS A 622
 None
 1.20A 5mejA-1fhqA:
undetectable		 5mejA-1fhqA:
17.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5MEW_A_CUA504_0
(LACCASE 2)		 1fhq PROTEIN KINASE SPK1
(Saccharomyces
cerevisiae) 		4 / 4 HIS A 651
CYH A 623
ILE A 680
HIS A 622
 None
 1.20A 5mewA-1fhqA:
undetectable		 5mewA-1fhqA:
17.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5MHU_A_CUA504_0
(LACCASE 2)		 1fhq PROTEIN KINASE SPK1
(Saccharomyces
cerevisiae) 		4 / 4 HIS A 651
CYH A 623
ILE A 680
HIS A 622
 None
 1.21A 5mhuA-1fhqA:
undetectable		 5mhuA-1fhqA:
17.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5MHV_A_CUA504_0
(LACCASE 2)		 1fhq PROTEIN KINASE SPK1
(Saccharomyces
cerevisiae) 		4 / 4 HIS A 651
CYH A 623
ILE A 680
HIS A 622
 None
 1.21A 5mhvA-1fhqA:
undetectable		 5mhvA-1fhqA:
17.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5MHW_A_CUA604_0
(LACCASE 2)		 1fhq PROTEIN KINASE SPK1
(Saccharomyces
cerevisiae) 		4 / 4 HIS A 651
CYH A 623
ILE A 680
HIS A 622
 None
 1.21A 5mhwA-1fhqA:
undetectable		 5mhwA-1fhqA:
13.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5MHX_A_CUA604_0
(LACCASE 2)		 1fhq PROTEIN KINASE SPK1
(Saccharomyces
cerevisiae) 		4 / 4 HIS A 651
CYH A 623
ILE A 680
HIS A 622
 None
 1.21A 5mhxA-1fhqA:
undetectable		 5mhxA-1fhqA:
13.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5MHY_A_CUA604_0
(LACCASE 2)		 1fhq PROTEIN KINASE SPK1
(Saccharomyces
cerevisiae) 		4 / 4 HIS A 651
CYH A 623
ILE A 680
HIS A 622
 None
 1.20A 5mhyA-1fhqA:
undetectable		 5mhyA-1fhqA:
13.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5MHZ_A_CUA604_0
(LACCASE 2)		 1fhq PROTEIN KINASE SPK1
(Saccharomyces
cerevisiae) 		4 / 4 HIS A 651
CYH A 623
ILE A 680
HIS A 622
 None
 1.21A 5mhzA-1fhqA:
undetectable		 5mhzA-1fhqA:
13.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5MI1_A_CUA604_0
(LACCASE 2)		 1fhq PROTEIN KINASE SPK1
(Saccharomyces
cerevisiae) 		4 / 4 HIS A 651
CYH A 623
ILE A 680
HIS A 622
 None
 1.21A 5mi1A-1fhqA:
undetectable		 5mi1A-1fhqA:
13.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5MI2_A_CUA604_0
(LACCASE 2)		 1fhq PROTEIN KINASE SPK1
(Saccharomyces
cerevisiae) 		4 / 4 HIS A 651
CYH A 623
ILE A 680
HIS A 622
 None
 1.21A 5mi2A-1fhqA:
undetectable		 5mi2A-1fhqA:
13.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5MIA_A_CUA604_0
(LACCASE 2)		 1fhq PROTEIN KINASE SPK1
(Saccharomyces
cerevisiae) 		4 / 4 HIS A 651
CYH A 623
ILE A 680
HIS A 622
 None
 1.20A 5miaA-1fhqA:
undetectable		 5miaA-1fhqA:
13.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5MIB_A_CUA604_0
(LACCASE 2)		 1fhq PROTEIN KINASE SPK1
(Saccharomyces
cerevisiae) 		4 / 4 HIS A 651
CYH A 623
ILE A 680
HIS A 622
 None
 1.21A 5mibA-1fhqA:
undetectable		 5mibA-1fhqA:
13.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5MIC_A_CUA604_0
(LACCASE 2)		 1fhq PROTEIN KINASE SPK1
(Saccharomyces
cerevisiae) 		4 / 4 HIS A 651
CYH A 623
ILE A 680
HIS A 622
 None
 1.21A 5micA-1fhqA:
undetectable		 5micA-1fhqA:
13.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5MID_A_CUA604_0
(LACCASE 2)		 1fhq PROTEIN KINASE SPK1
(Saccharomyces
cerevisiae) 		4 / 4 HIS A 651
CYH A 623
ILE A 680
HIS A 622
 None
 1.20A 5midA-1fhqA:
undetectable		 5midA-1fhqA:
13.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5MIE_A_CUA604_0
(LACCASE 2)		 1fhq PROTEIN KINASE SPK1
(Saccharomyces
cerevisiae) 		4 / 4 HIS A 651
CYH A 623
ILE A 680
HIS A 622
 None
 1.20A 5mieA-1fhqA:
undetectable		 5mieA-1fhqA:
13.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5MIG_A_CUA604_0
(LACCASE 2)		 1fhq PROTEIN KINASE SPK1
(Saccharomyces
cerevisiae) 		4 / 4 HIS A 651
CYH A 623
ILE A 680
HIS A 622
 None
 1.20A 5migA-1fhqA:
undetectable		 5migA-1fhqA:
13.50