SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '1fiq'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1P93_A_DEXA1999_1
(GLUCOCORTICOID
RECEPTOR)		 1fiq XANTHINE OXIDASE
(Bos
taurus) 		5 / 12 LEU A  30
LEU A  36
GLY A  35
THR A  24
ILE A  77
 None
 1.44A 1p93A-1fiqA:
undetectable		 1p93A-1fiqA:
19.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1XDK_B_9CRB600_2
(RETINOIC ACID
RECEPTOR, BETA)		 1fiq XANTHINE OXIDASE
(Bos
taurus) 		3 / 3 LEU A   6
PHE A   8
ARG A  32
 None
 0.83A 1xdkB-1fiqA:
undetectable		 1xdkB-1fiqA:
20.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1XDK_F_9CRF1600_2
(RETINOIC ACID
RECEPTOR, BETA)		 1fiq XANTHINE OXIDASE
(Bos
taurus) 		3 / 3 LEU A   6
PHE A   8
ARG A  32
 None
 0.83A 1xdkF-1fiqA:
undetectable		 1xdkF-1fiqA:
20.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4C5L_C_UEGC300_1
(PHOSPHOMETHYLPYRIMID
INE KINASE)		 1fiq XANTHINE OXIDASE
(Bos
taurus) 		5 / 10 GLY A 145
ALA A  50
GLY A  49
CYH A  43
CYH A  51
 None
FES  A 602 ( 4.9A)
FES  A 602 (-4.0A)
FES  A 602 (-2.4A)
FES  A 602 (-2.2A)
 1.12A 4c5lC-1fiqA:
undetectable		 4c5lC-1fiqA:
20.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4Q15_A_HFGA803_0
(PROLINE--TRNA LIGASE)		 1fiq XANTHINE OXIDASE
(Bos
taurus) 		5 / 12 LEU A 128
GLU A 103
VAL A 101
THR A 162
ARG A 104
 None
 1.29A 4q15A-1fiqA:
undetectable		 4q15A-1fiqA:
18.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4Q15_B_HFGB803_0
(PROLINE--TRNA LIGASE)		 1fiq XANTHINE OXIDASE
(Bos
taurus) 		5 / 12 LEU A 128
GLU A 103
VAL A 101
THR A 162
ARG A 104
 None
 1.29A 4q15B-1fiqA:
undetectable		 4q15B-1fiqA:
18.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5XIP_A_HFGA1003_0
(PROLYL-TRNA
SYNTHETASE, PUTATIVE)		 1fiq XANTHINE OXIDASE
(Bos
taurus) 		5 / 12 LEU A 128
GLU A 103
VAL A 101
THR A 162
ARG A 104
 None
 1.21A 5xipA-1fiqA:
undetectable		 5xipA-1fiqA:
19.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B0C_D_TA1D502_1
(TUBULIN BETA CHAIN)		 1fiq XANTHINE OXIDASE
(Bos
taurus) 		5 / 12 LEU A  55
SER A 123
LEU A  26
THR A  25
GLY A  46
 None
None
None
None
FES  A 602 ( 3.1A)
 0.98A 6b0cD-1fiqA:
undetectable		 6b0cD-1fiqA:
16.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6C06_D_FI8D1404_0
(DNA-DIRECTED RNA
POLYMERASE SUBUNIT
BETA
DNA-DIRECTED RNA
POLYMERASE SUBUNIT
BETA')		 1fiq XANTHINE OXIDASE
(Bos
taurus) 		4 / 8 ILE A 120
THR A 117
THR A  39
GLU A  89
 None
 0.97A 6c06C-1fiqA:
0.0		 6c06C-1fiqA:
undetectable