SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '1fj1'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1JTV_A_TESA500_1
(17
BETA-HYDROXYSTEROID
DEHYDROGENASE TYPE 1)		 1fj1 HYBRIDOMA ANTIBODY
LA2 (HEAVY CHAIN)
(Mus
musculus) 		4 / 8 VAL B 136
LEU B 138
PRO B 184
SER B 156
 None
 0.91A 1jtvA-1fj1B:
undetectable		 1jtvA-1fj1B:
19.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BRF_A_SORA2_0
(LIN-12 AND GLP-1
PHENOTYPE PROTEIN 1,
ISOFORM A)		 1fj1 HYBRIDOMA ANTIBODY
LA2 (HEAVY CHAIN)
(Mus
musculus) 		3 / 3 LYS B  12
LYS B  19
VAL B  18
 None
 1.08A 3brfA-1fj1B:
1.8		 3brfA-1fj1B:
18.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4OTW_A_DB8A1101_2
(RECEPTOR
TYROSINE-PROTEIN
KINASE ERBB-3)		 1fj1 HYBRIDOMA ANTIBODY
LA2 (HEAVY CHAIN)
(Mus
musculus) 		3 / 3 LEU B 159
LEU B 138
ASN B 155
 None
 0.68A 4otwA-1fj1B:
undetectable		 4otwA-1fj1B:
18.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ECM_D_LEUD602_0
(JASMONIC ACID-AMIDO
SYNTHETASE JAR1)		 1fj1 HYBRIDOMA ANTIBODY
LA2 (HEAVY CHAIN)
(Mus
musculus) 		4 / 7 ALA B  92
THR B  91
VAL B 109
GLU B  89
 None
 0.61A 5ecmD-1fj1B:
0.0		 5ecmD-1fj1B:
16.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ECN_D_LEUD602_0
(JASMONIC ACID-AMIDO
SYNTHETASE JAR1)		 1fj1 HYBRIDOMA ANTIBODY
LA2 (HEAVY CHAIN)
(Mus
musculus) 		4 / 8 ALA B  92
THR B  91
VAL B 109
GLU B  89
 None
 0.69A 5ecnD-1fj1B:
undetectable		 5ecnD-1fj1B:
16.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ECO_D_LEUD602_0
(JASMONIC ACID-AMIDO
SYNTHETASE JAR1)		 1fj1 HYBRIDOMA ANTIBODY
LA2 (HEAVY CHAIN)
(Mus
musculus) 		4 / 7 ALA B  92
THR B  91
VAL B 109
GLU B  89
 None
 0.73A 5ecoD-1fj1B:
0.0		 5ecoD-1fj1B:
16.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B58_A_ACTA606_0
(FUMARATE REDUCTASE
FLAVOPROTEIN SUBUNIT)		 1fj1 HYBRIDOMA ANTIBODY
LA2 (HEAVY CHAIN)
(Mus
musculus) 		4 / 5 GLU B 148
PHE B 146
HIS B 199
THR B 110
 None
 1.08A 6b58A-1fj1B:
undetectable		 6b58A-1fj1B:
15.71