SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '1fkk'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1BKF_A_FK5A108_1
(FK506 BINDING
PROTEIN)		 1fkk FK506 BINDING
PROTEIN
(Bos
taurus) 		8 / 9 TYR A  26
ASP A  37
PHE A  46
VAL A  55
ILE A  56
TRP A  59
TYR A  82
PHE A  99
 None
 0.49A 1bkfA-1fkkA:
22.1		 1bkfA-1fkkA:
95.33
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1C9H_A_RAPA108_1
(FKBP12.6)		 1fkk FK506 BINDING
PROTEIN
(Bos
taurus) 		6 / 12 ASP A  37
GLU A  54
TYR A  82
HIS A  87
ILE A  91
PHE A  99
 None
 0.91A 1c9hA-1fkkA:
21.9		 1c9hA-1fkkA:
85.05
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1C9H_A_RAPA108_1
(FKBP12.6)		 1fkk FK506 BINDING
PROTEIN
(Bos
taurus) 		9 / 12 TYR A  26
ASP A  37
PHE A  46
GLU A  54
VAL A  55
ILE A  56
TYR A  82
ILE A  91
PHE A  99
 None
 0.51A 1c9hA-1fkkA:
21.9		 1c9hA-1fkkA:
85.05
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1C9H_A_RAPA108_1
(FKBP12.6)		 1fkk FK506 BINDING
PROTEIN
(Bos
taurus) 		5 / 12 TYR A  26
PHE A  46
GLU A  54
VAL A  55
ILE A  90
 None
 1.15A 1c9hA-1fkkA:
21.9		 1c9hA-1fkkA:
85.05
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1FAP_A_RAPA108_1
(FK506-BINDING
PROTEIN)		 1fkk FK506 BINDING
PROTEIN
(Bos
taurus) 		12 / 12 TYR A  26
ASP A  37
PHE A  46
GLN A  53
GLU A  54
VAL A  55
ILE A  56
TRP A  59
TYR A  82
ILE A  90
ILE A  91
PHE A  99
 None
 0.57A 1fapA-1fkkA:
22.6		 1fapA-1fkkA:
97.20
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1FAP_A_RAPA108_1
(FK506-BINDING
PROTEIN)		 1fkk FK506 BINDING
PROTEIN
(Bos
taurus) 		6 / 12 TYR A  26
PHE A  46
GLN A  53
GLU A  54
VAL A  55
ILE A  90
 None
 1.14A 1fapA-1fkkA:
22.6		 1fapA-1fkkA:
97.20
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1FAP_A_RAPA108_1
(FK506-BINDING
PROTEIN)		 1fkk FK506 BINDING
PROTEIN
(Bos
taurus) 		7 / 12 TYR A  26
PHE A  46
GLU A  54
VAL A  55
TRP A  59
ILE A  91
PHE A  99
 None
 1.16A 1fapA-1fkkA:
22.6		 1fapA-1fkkA:
97.20
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1FKB_A_RAPA108_1
(FK506 BINDING
PROTEIN)		 1fkk FK506 BINDING
PROTEIN
(Bos
taurus) 		8 / 12 TYR A  26
ASP A  37
GLU A  54
TRP A  59
TYR A  82
HIS A  87
ILE A  90
PHE A  99
 None
 0.89A 1fkbA-1fkkA:
22.4		 1fkbA-1fkkA:
97.20
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1FKB_A_RAPA108_1
(FK506 BINDING
PROTEIN)		 1fkk FK506 BINDING
PROTEIN
(Bos
taurus) 		11 / 12 TYR A  26
ASP A  37
PHE A  46
GLN A  53
GLU A  54
VAL A  55
ILE A  56
TRP A  59
TYR A  82
ILE A  90
PHE A  99
 None
 0.69A 1fkbA-1fkkA:
22.4		 1fkbA-1fkkA:
97.20
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1FKB_A_RAPA108_1
(FK506 BINDING
PROTEIN)		 1fkk FK506 BINDING
PROTEIN
(Bos
taurus) 		6 / 12 TYR A  26
PHE A  46
GLU A  54
VAL A  55
TRP A  59
ILE A  91
 None
 1.19A 1fkbA-1fkkA:
22.4		 1fkbA-1fkkA:
97.20
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1FKF_A_FK5A108_1
(FK506 BINDING
PROTEIN)		 1fkk FK506 BINDING
PROTEIN
(Bos
taurus) 		10 / 11 ASP A  37
ARG A  42
PHE A  46
VAL A  55
ILE A  56
TRP A  59
TYR A  82
HIS A  87
ILE A  91
PHE A  99
 None
 0.70A 1fkfA-1fkkA:
22.3		 1fkfA-1fkkA:
97.20
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1FKF_A_FK5A108_1
(FK506 BINDING
PROTEIN)		 1fkk FK506 BINDING
PROTEIN
(Bos
taurus) 		10 / 11 TYR A  26
ASP A  37
ARG A  42
PHE A  46
VAL A  55
ILE A  56
TRP A  59
TYR A  82
ILE A  91
PHE A  99
 None
 0.46A 1fkfA-1fkkA:
22.3		 1fkfA-1fkkA:
97.20
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1FKF_A_FK5A108_1
(FK506 BINDING
PROTEIN)		 1fkk FK506 BINDING
PROTEIN
(Bos
taurus) 		5 / 11 TYR A  26
PHE A  46
VAL A  55
TRP A  59
ILE A  90
 None
 1.12A 1fkfA-1fkkA:
22.3		 1fkfA-1fkkA:
97.20
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1FKJ_A_FK5A108_1
(FK506 BINDING
PROTEIN)		 1fkk FK506 BINDING
PROTEIN
(Bos
taurus) 		10 / 11 ASP A  37
ARG A  42
PHE A  46
VAL A  55
ILE A  56
TRP A  59
TYR A  82
HIS A  87
ILE A  91
PHE A  99
 None
 0.68A 1fkjA-1fkkA:
22.2		 1fkjA-1fkkA:
97.20
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1FKJ_A_FK5A108_1
(FK506 BINDING
PROTEIN)		 1fkk FK506 BINDING
PROTEIN
(Bos
taurus) 		10 / 11 TYR A  26
ASP A  37
ARG A  42
PHE A  46
VAL A  55
ILE A  56
TRP A  59
TYR A  82
ILE A  91
PHE A  99
 None
 0.46A 1fkjA-1fkkA:
22.2		 1fkjA-1fkkA:
97.20
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1FKJ_A_FK5A108_1
(FK506 BINDING
PROTEIN)		 1fkk FK506 BINDING
PROTEIN
(Bos
taurus) 		5 / 11 TYR A  26
PHE A  46
VAL A  55
TRP A  59
ILE A  90
 None
 1.14A 1fkjA-1fkkA:
22.2		 1fkjA-1fkkA:
97.20
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1FKL_A_RAPA108_1
(FK506 BINDING
PROTEIN)		 1fkk FK506 BINDING
PROTEIN
(Bos
taurus) 		9 / 12 TYR A  26
ASP A  37
ILE A  56
TRP A  59
TYR A  82
HIS A  87
ILE A  90
ILE A  91
PHE A  99
 None
 0.71A 1fklA-1fkkA:
22.2		 1fklA-1fkkA:
100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1FKL_A_RAPA108_1
(FK506 BINDING
PROTEIN)		 1fkk FK506 BINDING
PROTEIN
(Bos
taurus) 		10 / 12 TYR A  26
ASP A  37
PHE A  46
VAL A  55
ILE A  56
TRP A  59
TYR A  82
ILE A  90
ILE A  91
PHE A  99
 None
 0.45A 1fklA-1fkkA:
22.2		 1fklA-1fkkA:
100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1FKL_A_RAPA108_1
(FK506 BINDING
PROTEIN)		 1fkk FK506 BINDING
PROTEIN
(Bos
taurus) 		9 / 12 TYR A  26
GLU A  54
ILE A  56
TRP A  59
TYR A  82
HIS A  87
ILE A  90
ILE A  91
PHE A  99
 None
 0.77A 1fklA-1fkkA:
22.2		 1fklA-1fkkA:
100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1FKL_A_RAPA108_1
(FK506 BINDING
PROTEIN)		 1fkk FK506 BINDING
PROTEIN
(Bos
taurus) 		10 / 12 TYR A  26
PHE A  46
GLU A  54
VAL A  55
ILE A  56
TRP A  59
TYR A  82
ILE A  90
ILE A  91
PHE A  99
 None
 0.50A 1fklA-1fkkA:
22.2		 1fklA-1fkkA:
100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1PBK_A_RAPA225_1
(FKBP25)		 1fkk FK506 BINDING
PROTEIN
(Bos
taurus) 		8 / 12 TYR A  26
ASP A  37
VAL A  55
ILE A  56
TRP A  59
TYR A  82
ILE A  91
PHE A  99
 None
 0.54A 1pbkA-1fkkA:
19.5		 1pbkA-1fkkA:
44.17
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1Q6I_A_FK5A301_1
(FKBP-TYPE
PEPTIDYL-PROLYL
CIS-TRANS ISOMERASE
FKPA)		 1fkk FK506 BINDING
PROTEIN
(Bos
taurus) 		8 / 9 TYR A  26
ASP A  37
VAL A  55
ILE A  56
TRP A  59
TYR A  82
ILE A  91
PHE A  99
 None
 0.54A 1q6iA-1fkkA:
16.3		 1q6iA-1fkkA:
32.16
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1Q6I_B_FK5B401_1
(FKBP-TYPE
PEPTIDYL-PROLYL
CIS-TRANS ISOMERASE
FKPA)		 1fkk FK506 BINDING
PROTEIN
(Bos
taurus) 		9 / 10 TYR A  26
ASP A  37
ARG A  42
VAL A  55
ILE A  56
TRP A  59
TYR A  82
ILE A  91
PHE A  99
 None
 0.55A 1q6iB-1fkkA:
16.0		 1q6iB-1fkkA:
32.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1SGU_B_MK1B2632_1
(POL POLYPROTEIN)		 1fkk FK506 BINDING
PROTEIN
(Bos
taurus) 		5 / 8 ALA A  72
GLY A  10
GLY A  69
PRO A  16
ALA A  64
 None
 1.10A 1sguA-1fkkA:
undetectable		 1sguA-1fkkA:
21.74
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1TCO_C_FK5C509_2
(FK506-BINDING
PROTEIN)		 1fkk FK506 BINDING
PROTEIN
(Bos
taurus) 		10 / 11 TYR A  26
ASP A  37
ARG A  42
PHE A  46
VAL A  55
ILE A  56
TRP A  59
TYR A  82
ILE A  91
PHE A  99
 None
 0.57A 1tcoC-1fkkA:
22.3		 1tcoC-1fkkA:
96.26
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1TCO_C_FK5C509_2
(FK506-BINDING
PROTEIN)		 1fkk FK506 BINDING
PROTEIN
(Bos
taurus) 		7 / 11 TYR A  26
ASP A  37
ARG A  42
TRP A  59
HIS A  87
ILE A  91
PHE A  99
 None
 0.99A 1tcoC-1fkkA:
22.3		 1tcoC-1fkkA:
96.26
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1YAT_A_FK5A108_1
(FK506 BINDING
PROTEIN)		 1fkk FK506 BINDING
PROTEIN
(Bos
taurus) 		10 / 11 TYR A  26
ASP A  37
ARG A  42
PHE A  46
VAL A  55
ILE A  56
TRP A  59
TYR A  82
ILE A  91
PHE A  99
 None
 0.50A 1yatA-1fkkA:
20.6		 1yatA-1fkkA:
57.41
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2DG3_A_RAPA501_1
(FK506-BINDING
PROTEIN 1A)		 1fkk FK506 BINDING
PROTEIN
(Bos
taurus) 		8 / 11 TYR A  26
ASP A  37
GLU A  54
TRP A  59
TYR A  82
HIS A  87
ILE A  90
PHE A  99
 None
 0.93A 2dg3A-1fkkA:
22.2		 2dg3A-1fkkA:
97.20
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2DG3_A_RAPA501_1
(FK506-BINDING
PROTEIN 1A)		 1fkk FK506 BINDING
PROTEIN
(Bos
taurus) 		5 / 11 TYR A  26
ASP A  37
PHE A  46
GLU A  54
ILE A  91
 None
 1.19A 2dg3A-1fkkA:
22.2		 2dg3A-1fkkA:
97.20
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2DG3_A_RAPA501_1
(FK506-BINDING
PROTEIN 1A)		 1fkk FK506 BINDING
PROTEIN
(Bos
taurus) 		10 / 11 TYR A  26
ASP A  37
PHE A  46
GLU A  54
VAL A  55
ILE A  56
TRP A  59
TYR A  82
ILE A  90
PHE A  99
 None
 0.59A 2dg3A-1fkkA:
22.2		 2dg3A-1fkkA:
97.20
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2DG4_A_RAPA501_1
(FK506-BINDING
PROTEIN 1A)		 1fkk FK506 BINDING
PROTEIN
(Bos
taurus) 		5 / 11 ASP A  37
TYR A  82
HIS A  87
ILE A  90
PHE A  99
 None
 0.83A 2dg4A-1fkkA:
21.7		 2dg4A-1fkkA:
96.26
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2DG4_A_RAPA501_1
(FK506-BINDING
PROTEIN 1A)		 1fkk FK506 BINDING
PROTEIN
(Bos
taurus) 		9 / 11 TYR A  26
ASP A  37
PHE A  46
GLU A  54
VAL A  55
ILE A  56
TYR A  82
ILE A  90
PHE A  99
 None
 0.51A 2dg4A-1fkkA:
21.7		 2dg4A-1fkkA:
96.26
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2DG4_A_RAPA501_1
(FK506-BINDING
PROTEIN 1A)		 1fkk FK506 BINDING
PROTEIN
(Bos
taurus) 		5 / 11 TYR A  26
PHE A  46
GLU A  54
VAL A  55
ILE A  91
 None
 1.01A 2dg4A-1fkkA:
21.7		 2dg4A-1fkkA:
96.26
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2DG9_A_RAPA501_1
(FK506-BINDING
PROTEIN 1A)		 1fkk FK506 BINDING
PROTEIN
(Bos
taurus) 		7 / 11 TYR A  26
ASP A  37
ILE A  56
TYR A  82
HIS A  87
ILE A  90
PHE A  99
 None
 0.77A 2dg9A-1fkkA:
22.0		 2dg9A-1fkkA:
96.26
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2DG9_A_RAPA501_1
(FK506-BINDING
PROTEIN 1A)		 1fkk FK506 BINDING
PROTEIN
(Bos
taurus) 		9 / 11 TYR A  26
ASP A  37
PHE A  46
GLU A  54
VAL A  55
ILE A  56
TYR A  82
ILE A  90
PHE A  99
 None
 0.49A 2dg9A-1fkkA:
22.0		 2dg9A-1fkkA:
96.26
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2DG9_A_RAPA501_1
(FK506-BINDING
PROTEIN 1A)		 1fkk FK506 BINDING
PROTEIN
(Bos
taurus) 		5 / 11 TYR A  26
PHE A  46
GLU A  54
VAL A  55
ILE A  91
 None
 1.08A 2dg9A-1fkkA:
22.0		 2dg9A-1fkkA:
96.26
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2FKE_A_FK5A108_1
(FK506 BINDING
PROTEIN)		 1fkk FK506 BINDING
PROTEIN
(Bos
taurus) 		10 / 11 ASP A  37
ARG A  42
PHE A  46
VAL A  55
ILE A  56
TRP A  59
TYR A  82
HIS A  87
ILE A  91
PHE A  99
 None
 0.69A 2fkeA-1fkkA:
22.2		 2fkeA-1fkkA:
97.20
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2FKE_A_FK5A108_1
(FK506 BINDING
PROTEIN)		 1fkk FK506 BINDING
PROTEIN
(Bos
taurus) 		10 / 11 TYR A  26
ASP A  37
ARG A  42
PHE A  46
VAL A  55
ILE A  56
TRP A  59
TYR A  82
ILE A  91
PHE A  99
 None
 0.45A 2fkeA-1fkkA:
22.2		 2fkeA-1fkkA:
97.20
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2FKE_A_FK5A108_1
(FK506 BINDING
PROTEIN)		 1fkk FK506 BINDING
PROTEIN
(Bos
taurus) 		5 / 11 TYR A  26
PHE A  46
VAL A  55
TRP A  59
ILE A  90
 None
 1.12A 2fkeA-1fkkA:
22.2		 2fkeA-1fkkA:
97.20
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2VCD_A_RAPA138_1
(OUTER MEMBRANE
PROTEIN MIP)		 1fkk FK506 BINDING
PROTEIN
(Bos
taurus) 		7 / 11 TYR A  26
PHE A  36
ASP A  37
VAL A  55
ILE A  56
TRP A  59
TYR A  82
 None
 0.98A 2vcdA-1fkkA:
13.6		 2vcdA-1fkkA:
35.90
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2VN1_A_FK5A501_1
(70 KDA
PEPTIDYLPROLYL
ISOMERASE)		 1fkk FK506 BINDING
PROTEIN
(Bos
taurus) 		10 / 11 TYR A  26
PHE A  36
ASP A  37
ARG A  42
PHE A  46
VAL A  55
TRP A  59
TYR A  82
ILE A  91
PHE A  99
 None
 0.60A 2vn1A-1fkkA:
19.4		 2vn1A-1fkkA:
41.09
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2VN1_B_FK5B501_1
(70 KDA
PEPTIDYLPROLYL
ISOMERASE)		 1fkk FK506 BINDING
PROTEIN
(Bos
taurus) 		9 / 10 TYR A  26
ASP A  37
ARG A  42
PHE A  46
VAL A  55
ILE A  56
TRP A  59
TYR A  82
PHE A  99
 None
 0.58A 2vn1B-1fkkA:
19.4		 2vn1B-1fkkA:
41.09
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3IHZ_A_FK5A501_1
(70 KDA
PEPTIDYLPROLYL
ISOMERASE, PUTATIVE)		 1fkk FK506 BINDING
PROTEIN
(Bos
taurus) 		10 / 10 TYR A  26
ASP A  37
ARG A  42
PHE A  46
VAL A  55
ILE A  56
TRP A  59
TYR A  82
ILE A  91
PHE A  99
 None
 0.48A 3ihzA-1fkkA:
19.3		 3ihzA-1fkkA:
40.91
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3IHZ_A_FK5A501_2
(70 KDA
PEPTIDYLPROLYL
ISOMERASE, PUTATIVE)		 1fkk FK506 BINDING
PROTEIN
(Bos
taurus) 		6 / 8 TYR A  26
ASP A  37
PHE A  46
TRP A  59
TYR A  82
ILE A  91
 None
 0.55A 3ihzB-1fkkA:
19.7		 3ihzB-1fkkA:
40.91
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3KZ7_A_RAPA225_1
(FK506-BINDING
PROTEIN 3)		 1fkk FK506 BINDING
PROTEIN
(Bos
taurus) 		8 / 10 TYR A  26
ASP A  37
VAL A  55
ILE A  56
TRP A  59
TYR A  82
ILE A  91
PHE A  99
 None
 0.51A 3kz7A-1fkkA:
19.3		 3kz7A-1fkkA:
45.83
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3O5R_A_FK5A1001_1
(PEPTIDYL-PROLYL
CIS-TRANS ISOMERASE
FKBP5)		 1fkk FK506 BINDING
PROTEIN
(Bos
taurus) 		10 / 11 TYR A  26
ASP A  37
ARG A  42
PHE A  46
VAL A  55
ILE A  56
TRP A  59
TYR A  82
ILE A  91
PHE A  99
 None
 0.53A 3o5rA-1fkkA:
19.1		 3o5rA-1fkkA:
45.31
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3UF8_A_FK5A114_1
(UBIQUITIN-LIKE
PROTEIN SMT3,
PEPTIDYL-PROLYL
CIS-TRANS ISOMERASE)		 1fkk FK506 BINDING
PROTEIN
(Bos
taurus) 		10 / 10 TYR A  26
ASP A  37
ARG A  42
PHE A  46
VAL A  55
ILE A  56
TRP A  59
TYR A  82
ILE A  91
PHE A  99
 None
 0.50A 3uf8A-1fkkA:
18.9		 3uf8A-1fkkA:
32.21
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3UQA_A_FK5A114_1
(UBIQUITIN-LIKE
PROTEIN SMT3,
PEPTIDYL-PROLYL
CIS-TRANS ISOMERASE)		 1fkk FK506 BINDING
PROTEIN
(Bos
taurus) 		10 / 10 TYR A  26
ASP A  37
ARG A  42
PHE A  46
VAL A  55
ILE A  56
TRP A  59
TYR A  82
ILE A  91
PHE A  99
 None
 0.58A 3uqaA-1fkkA:
18.9		 3uqaA-1fkkA:
32.21
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3UQB_A_FK5A114_1
(UBIQUITIN-LIKE
PROTEIN SMT3,
PEPTIDYL-PROLYL
CIS-TRANS ISOMERASE)		 1fkk FK506 BINDING
PROTEIN
(Bos
taurus) 		8 / 8 TYR A  26
PHE A  46
VAL A  55
ILE A  56
TRP A  59
TYR A  82
ILE A  91
PHE A  99
 None
 0.41A 3uqbA-1fkkA:
18.5		 3uqbA-1fkkA:
31.73
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3VAW_A_FK5A114_1
(UBIQUITIN-LIKE
PROTEIN
SMT3,PEPTIDYL-PROLYL
CIS-TRANS ISOMERASE)		 1fkk FK506 BINDING
PROTEIN
(Bos
taurus) 		10 / 11 TYR A  26
ASP A  37
ARG A  42
PHE A  46
VAL A  55
ILE A  56
TRP A  59
TYR A  82
ILE A  91
PHE A  99
 None
 0.50A 3vawA-1fkkA:
18.0		 3vawA-1fkkA:
32.21
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4DRH_A_RAPA201_1
(PEPTIDYL-PROLYL
CIS-TRANS ISOMERASE
FKBP5)		 1fkk FK506 BINDING
PROTEIN
(Bos
taurus) 		9 / 12 TYR A  26
ASP A  37
PHE A  46
VAL A  55
ILE A  56
TRP A  59
TYR A  82
ILE A  91
PHE A  99
 None
 0.50A 4drhA-1fkkA:
17.8		 4drhA-1fkkA:
40.28
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4DRH_D_RAPD201_1
(PEPTIDYL-PROLYL
CIS-TRANS ISOMERASE
FKBP5)		 1fkk FK506 BINDING
PROTEIN
(Bos
taurus) 		9 / 12 TYR A  26
ASP A  37
PHE A  46
VAL A  55
ILE A  56
TRP A  59
TYR A  82
ILE A  91
PHE A  99
 None
 0.46A 4drhD-1fkkA:
17.6		 4drhD-1fkkA:
40.28
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4DRI_A_RAPA201_1
(PEPTIDYL-PROLYL
CIS-TRANS ISOMERASE
FKBP5)		 1fkk FK506 BINDING
PROTEIN
(Bos
taurus) 		8 / 11 TYR A  26
ASP A  37
ARG A  42
ILE A  56
TRP A  59
TYR A  82
ILE A  91
PHE A  99
 None
 0.87A 4driA-1fkkA:
19.8		 4driA-1fkkA:
40.28
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4DRI_A_RAPA201_1
(PEPTIDYL-PROLYL
CIS-TRANS ISOMERASE
FKBP5)		 1fkk FK506 BINDING
PROTEIN
(Bos
taurus) 		9 / 11 TYR A  26
ASP A  37
PHE A  46
VAL A  55
ILE A  56
TRP A  59
TYR A  82
ILE A  91
PHE A  99
 None
 0.39A 4driA-1fkkA:
19.8		 4driA-1fkkA:
40.28
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4DRJ_A_RAPA201_1
(PEPTIDYL-PROLYL
CIS-TRANS ISOMERASE
FKBP4)		 1fkk FK506 BINDING
PROTEIN
(Bos
taurus) 		9 / 11 TYR A  26
ASP A  37
PHE A  46
VAL A  55
ILE A  56
TRP A  59
TYR A  82
ILE A  91
PHE A  99
 None
 0.43A 4drjA-1fkkA:
19.3		 4drjA-1fkkA:
40.28
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4DRJ_A_RAPA201_1
(PEPTIDYL-PROLYL
CIS-TRANS ISOMERASE
FKBP4)		 1fkk FK506 BINDING
PROTEIN
(Bos
taurus) 		9 / 11 TYR A  26
PHE A  46
GLU A  54
VAL A  55
ILE A  56
TRP A  59
TYR A  82
ILE A  91
PHE A  99
 None
 0.60A 4drjA-1fkkA:
19.3		 4drjA-1fkkA:
40.28
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4DRJ_A_RAPA201_1
(PEPTIDYL-PROLYL
CIS-TRANS ISOMERASE
FKBP4)		 1fkk FK506 BINDING
PROTEIN
(Bos
taurus) 		5 / 11 TYR A  26
PHE A  46
GLU A  54
VAL A  55
ILE A  90
 None
 1.20A 4drjA-1fkkA:
19.3		 4drjA-1fkkA:
40.28
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4DZ2_A_FK5A200_1
(PEPTIDYL-PROLYL
CIS-TRANS ISOMERASE)		 1fkk FK506 BINDING
PROTEIN
(Bos
taurus) 		10 / 11 TYR A  26
ASP A  37
ARG A  42
PHE A  46
VAL A  55
ILE A  56
TRP A  59
TYR A  82
ILE A  91
PHE A  99
 None
 0.72A 4dz2A-1fkkA:
18.8
4dz2B-1fkkA:
18.8		 4dz2A-1fkkA:
54.87
4dz2B-1fkkA:
54.87
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4DZ2_B_FK5B200_1
(PEPTIDYL-PROLYL
CIS-TRANS ISOMERASE)		 1fkk FK506 BINDING
PROTEIN
(Bos
taurus) 		10 / 11 TYR A  26
ASP A  37
ARG A  42
PHE A  46
VAL A  55
ILE A  56
TRP A  59
TYR A  82
ILE A  91
PHE A  99
 None
 0.71A 4dz2A-1fkkA:
18.8
4dz2B-1fkkA:
18.8		 4dz2A-1fkkA:
54.87
4dz2B-1fkkA:
54.87
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4DZ3_A_FK5A201_1
(PEPTIDYL-PROLYL
CIS-TRANS ISOMERASE)		 1fkk FK506 BINDING
PROTEIN
(Bos
taurus) 		10 / 10 TYR A  26
ASP A  37
ARG A  42
PHE A  46
VAL A  55
ILE A  56
TRP A  59
TYR A  82
ILE A  91
PHE A  99
 None
 0.63A 4dz3A-1fkkA:
19.0		 4dz3A-1fkkA:
54.87
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4DZ3_B_FK5B201_1
(PEPTIDYL-PROLYL
CIS-TRANS ISOMERASE)		 1fkk FK506 BINDING
PROTEIN
(Bos
taurus) 		10 / 10 TYR A  26
ASP A  37
ARG A  42
PHE A  46
VAL A  55
ILE A  56
TRP A  59
TYR A  82
ILE A  91
PHE A  99
 None
 0.50A 4dz3B-1fkkA:
19.0		 4dz3B-1fkkA:
54.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4LAX_A_FK5A301_1
(PEPTIDYL-PROLYL
CIS-TRANS ISOMERASE
FKBP4)		 1fkk FK506 BINDING
PROTEIN
(Bos
taurus) 		9 / 10 TYR A  26
ASP A  37
PHE A  46
VAL A  55
ILE A  56
TRP A  59
TYR A  82
ILE A  91
PHE A  99
 None
 0.48A 4laxA-1fkkA:
19.7		 4laxA-1fkkA:
24.79
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4NNR_A_FK5A201_1
(PEPTIDYL-PROLYL
CIS-TRANS ISOMERASE
FKBP2)		 1fkk FK506 BINDING
PROTEIN
(Bos
taurus) 		9 / 12 TYR A  26
ASP A  37
PHE A  46
VAL A  55
ILE A  56
TRP A  59
TYR A  82
ILE A  91
PHE A  99
 None
 0.52A 4nnrA-1fkkA:
16.2
4nnrB-1fkkA:
16.2		 4nnrA-1fkkA:
39.42
4nnrB-1fkkA:
39.42
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4NNR_B_FK5B201_1
(PEPTIDYL-PROLYL
CIS-TRANS ISOMERASE
FKBP2)		 1fkk FK506 BINDING
PROTEIN
(Bos
taurus) 		9 / 10 TYR A  26
ASP A  37
PHE A  46
VAL A  55
ILE A  56
TRP A  59
TYR A  82
ILE A  91
PHE A  99
 None
 0.58A 4nnrB-1fkkA:
16.2		 4nnrB-1fkkA:
39.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ODO_A_FK5A205_1
(PEPTIDYL-PROLYL
CIS-TRANS ISOMERASE
SLYD)		 1fkk FK506 BINDING
PROTEIN
(Bos
taurus) 		5 / 10 TYR A  26
ASP A  37
ILE A  56
TYR A  82
PHE A  99
 None
 0.50A 4odoA-1fkkA:
12.1		 4odoA-1fkkA:
23.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ODO_B_FK5B203_1
(PEPTIDYL-PROLYL
CIS-TRANS ISOMERASE
SLYD)		 1fkk FK506 BINDING
PROTEIN
(Bos
taurus) 		5 / 10 TYR A  26
ASP A  37
ILE A  56
TYR A  82
PHE A  99
 None
 0.49A 4odoB-1fkkA:
11.8		 4odoB-1fkkA:
23.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ODO_C_FK5C204_1
(PEPTIDYL-PROLYL
CIS-TRANS ISOMERASE
SLYD)		 1fkk FK506 BINDING
PROTEIN
(Bos
taurus) 		5 / 10 TYR A  26
ASP A  37
ILE A  56
TYR A  82
PHE A  99
 None
 0.51A 4odoC-1fkkA:
11.7		 4odoC-1fkkA:
23.31
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4ODR_A_FK5A201_1
(PEPTIDYL-PROLYL
CIS-TRANS ISOMERASE
SLYD,
PEPTIDYL-PROLYL
CIS-TRANS ISOMERASE
FKBP1A CHIMERA)		 1fkk FK506 BINDING
PROTEIN
(Bos
taurus) 		7 / 12 TYR A  26
ASP A  37
ILE A  56
TYR A  82
ILE A  90
ILE A  91
PHE A  99
 None
 0.62A 4odrA-1fkkA:
13.9
4odrB-1fkkA:
14.0		 4odrA-1fkkA:
32.79
4odrB-1fkkA:
32.79
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4ODR_B_FK5B201_1
(PEPTIDYL-PROLYL
CIS-TRANS ISOMERASE
SLYD,
PEPTIDYL-PROLYL
CIS-TRANS ISOMERASE
FKBP1A CHIMERA)		 1fkk FK506 BINDING
PROTEIN
(Bos
taurus) 		6 / 11 TYR A  26
ASP A  37
ILE A  56
TYR A  82
ILE A  90
PHE A  99
 None
 0.51A 4odrA-1fkkA:
13.9
4odrB-1fkkA:
14.0		 4odrA-1fkkA:
32.79
4odrB-1fkkA:
32.79
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4QT2_A_RAPA202_1
(FK506-BINDING
PROTEIN (FKBP)-TYPE
PEPTIDYL-PROPYL
ISOMERASE)		 1fkk FK506 BINDING
PROTEIN
(Bos
taurus) 		10 / 10 TYR A  26
ASP A  37
PHE A  46
GLU A  54
VAL A  55
ILE A  56
TRP A  59
TYR A  82
ILE A  91
PHE A  99
 None
 0.59A 4qt2A-1fkkA:
19.9		 4qt2A-1fkkA:
42.28
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4QT2_A_RAPA202_1
(FK506-BINDING
PROTEIN (FKBP)-TYPE
PEPTIDYL-PROPYL
ISOMERASE)		 1fkk FK506 BINDING
PROTEIN
(Bos
taurus) 		5 / 10 TYR A  26
PHE A  46
GLU A  54
VAL A  55
ILE A  90
 None
 1.15A 4qt2A-1fkkA:
19.9		 4qt2A-1fkkA:
42.28
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4QT3_A_RAPA202_1
(FK506-BINDING
PROTEIN (FKBP)-TYPE
PEPTIDYL-PROPYL
ISOMERASE)		 1fkk FK506 BINDING
PROTEIN
(Bos
taurus) 		9 / 10 TYR A  26
ASP A  37
PHE A  46
VAL A  55
ILE A  56
TRP A  59
TYR A  82
ILE A  91
PHE A  99
 None
 0.46A 4qt3A-1fkkA:
18.1		 4qt3A-1fkkA:
41.60
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4QT3_A_RAPA202_1
(FK506-BINDING
PROTEIN (FKBP)-TYPE
PEPTIDYL-PROPYL
ISOMERASE)		 1fkk FK506 BINDING
PROTEIN
(Bos
taurus) 		9 / 10 TYR A  26
PHE A  46
GLU A  54
VAL A  55
ILE A  56
TRP A  59
TYR A  82
ILE A  91
PHE A  99
 None
 0.56A 4qt3A-1fkkA:
18.1		 4qt3A-1fkkA:
41.60
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4QT3_A_RAPA202_1
(FK506-BINDING
PROTEIN (FKBP)-TYPE
PEPTIDYL-PROPYL
ISOMERASE)		 1fkk FK506 BINDING
PROTEIN
(Bos
taurus) 		5 / 10 TYR A  26
PHE A  46
GLU A  54
VAL A  55
ILE A  90
 None
 1.11A 4qt3A-1fkkA:
18.1		 4qt3A-1fkkA:
41.60
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5B8I_C_FK5C201_3
(PEPTIDYL-PROLYL
CIS-TRANS ISOMERASE)		 1fkk FK506 BINDING
PROTEIN
(Bos
taurus) 		10 / 12 TYR A  26
ASP A  37
ARG A  42
PHE A  46
VAL A  55
ILE A  56
TRP A  59
TYR A  82
ILE A  91
PHE A  99
 None
 0.67A 5b8iC-1fkkA:
19.8		 5b8iC-1fkkA:
41.98
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5D75_A_FK5A301_1
(PEPTIDYL-PROLYL
CIS-TRANS ISOMERASE
FKBP3)		 1fkk FK506 BINDING
PROTEIN
(Bos
taurus) 		8 / 11 TYR A  26
ASP A  37
VAL A  55
ILE A  56
TRP A  59
TYR A  82
ILE A  91
PHE A  99
 None
 0.48A 5d75A-1fkkA:
19.5		 5d75A-1fkkA:
45.08
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5GPG_A_RAPA301_1
(PEPTIDYL-PROLYL
CIS-TRANS ISOMERASE
FKBP3)		 1fkk FK506 BINDING
PROTEIN
(Bos
taurus) 		8 / 11 TYR A  26
ASP A  37
VAL A  55
ILE A  56
TRP A  59
TYR A  82
ILE A  91
PHE A  99
 None
 0.48A 5gpgA-1fkkA:
20.3		 5gpgA-1fkkA:
44.17
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5HKG_A_RAPA201_1
(PEPTIDYL-PROLYL
CIS-TRANS ISOMERASE
FKBP1B)		 1fkk FK506 BINDING
PROTEIN
(Bos
taurus) 		7 / 12 TYR A  26
ASP A  37
GLU A  54
TYR A  82
HIS A  87
ILE A  91
PHE A  99
 None
 0.92A 5hkgA-1fkkA:
21.8		 5hkgA-1fkkA:
85.05
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5HKG_A_RAPA201_1
(PEPTIDYL-PROLYL
CIS-TRANS ISOMERASE
FKBP1B)		 1fkk FK506 BINDING
PROTEIN
(Bos
taurus) 		9 / 12 TYR A  26
ASP A  37
PHE A  46
GLU A  54
VAL A  55
ILE A  56
TYR A  82
ILE A  91
PHE A  99
 None
 0.55A 5hkgA-1fkkA:
21.8		 5hkgA-1fkkA:
85.05
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5HKG_A_RAPA201_1
(PEPTIDYL-PROLYL
CIS-TRANS ISOMERASE
FKBP1B)		 1fkk FK506 BINDING
PROTEIN
(Bos
taurus) 		5 / 12 TYR A  26
PHE A  46
GLU A  54
VAL A  55
ILE A  90
 None
 1.13A 5hkgA-1fkkA:
21.8		 5hkgA-1fkkA:
85.05
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5HUA_A_FK5A201_1
(FK506-BINDING
PROTEIN 1)		 1fkk FK506 BINDING
PROTEIN
(Bos
taurus) 		9 / 11 TYR A  26
ASP A  37
ARG A  42
PHE A  46
VAL A  55
ILE A  56
TRP A  59
TYR A  82
PHE A  99
 None
 0.51A 5huaA-1fkkA:
20.9		 5huaA-1fkkA:
58.88
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5HW8_A_FK5A201_1
(FK506-BINDING
PROTEIN 1)		 1fkk FK506 BINDING
PROTEIN
(Bos
taurus) 		9 / 11 TYR A  26
ASP A  37
ARG A  42
PHE A  46
VAL A  55
ILE A  56
TRP A  59
TYR A  82
ILE A  91
 None
 0.83A 5hw8A-1fkkA:
19.0
5hw8D-1fkkA:
18.9		 5hw8A-1fkkA:
45.83
5hw8D-1fkkA:
45.83
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5HW8_A_FK5A201_1
(FK506-BINDING
PROTEIN 1)		 1fkk FK506 BINDING
PROTEIN
(Bos
taurus) 		5 / 11 TYR A  26
PHE A  46
VAL A  55
TRP A  59
ILE A  90
 None
 0.98A 5hw8A-1fkkA:
19.0
5hw8D-1fkkA:
18.9		 5hw8A-1fkkA:
45.83
5hw8D-1fkkA:
45.83
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5HW8_B_FK5B201_1
(FK506-BINDING
PROTEIN 1)		 1fkk FK506 BINDING
PROTEIN
(Bos
taurus) 		9 / 11 TYR A  26
ASP A  37
ARG A  42
PHE A  46
VAL A  55
TRP A  59
TYR A  82
ILE A  91
PHE A  99
 None
 0.69A 5hw8B-1fkkA:
18.8		 5hw8B-1fkkA:
45.83
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5HW8_B_FK5B201_1
(FK506-BINDING
PROTEIN 1)		 1fkk FK506 BINDING
PROTEIN
(Bos
taurus) 		9 / 11 TYR A  26
ASP A  37
PHE A  46
VAL A  55
TRP A  59
TYR A  82
ILE A  90
ILE A  91
PHE A  99
 None
 0.54A 5hw8B-1fkkA:
18.8		 5hw8B-1fkkA:
45.83
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5HW8_B_FK5B201_1
(FK506-BINDING
PROTEIN 1)		 1fkk FK506 BINDING
PROTEIN
(Bos
taurus) 		7 / 11 TYR A  26
PHE A  46
VAL A  55
TRP A  59
ILE A  90
ILE A  91
PHE A  99
 None
 1.44A 5hw8B-1fkkA:
18.8		 5hw8B-1fkkA:
45.83
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5HW8_C_FK5C201_1
(FK506-BINDING
PROTEIN 1)		 1fkk FK506 BINDING
PROTEIN
(Bos
taurus) 		9 / 10 TYR A  26
ASP A  37
ARG A  42
VAL A  55
ILE A  56
TRP A  59
TYR A  82
LEU A  97
PHE A  99
 None
 0.77A 5hw8C-1fkkA:
18.7
5hw8H-1fkkA:
15.7		 5hw8C-1fkkA:
45.83
5hw8H-1fkkA:
45.83
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5HW8_D_FK5D201_1
(FK506-BINDING
PROTEIN 1)		 1fkk FK506 BINDING
PROTEIN
(Bos
taurus) 		11 / 11 TYR A  26
ASP A  37
ARG A  42
PHE A  46
VAL A  55
ILE A  56
TRP A  59
TYR A  82
ILE A  90
ILE A  91
PHE A  99
 None
 0.58A 5hw8D-1fkkA:
18.9		 5hw8D-1fkkA:
45.83
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5HW8_D_FK5D201_1
(FK506-BINDING
PROTEIN 1)		 1fkk FK506 BINDING
PROTEIN
(Bos
taurus) 		5 / 11 TYR A  26
PHE A  46
VAL A  55
TRP A  59
ILE A  90
 None
 1.06A 5hw8D-1fkkA:
18.9		 5hw8D-1fkkA:
45.83
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5HW8_E_FK5E201_1
(FK506-BINDING
PROTEIN 1)		 1fkk FK506 BINDING
PROTEIN
(Bos
taurus) 		6 / 11 TYR A  26
ARG A  42
PHE A  46
TRP A  59
ILE A  90
PHE A  99
 None
 1.14A 5hw8E-1fkkA:
18.8		 5hw8E-1fkkA:
45.83
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5HW8_E_FK5E201_1
(FK506-BINDING
PROTEIN 1)		 1fkk FK506 BINDING
PROTEIN
(Bos
taurus) 		10 / 11 TYR A  26
ASP A  37
ARG A  42
PHE A  46
VAL A  55
ILE A  56
TRP A  59
TYR A  82
ILE A  90
PHE A  99
 None
 0.71A 5hw8E-1fkkA:
18.8		 5hw8E-1fkkA:
45.83
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5HW8_F_FK5F201_1
(FK506-BINDING
PROTEIN 1)		 1fkk FK506 BINDING
PROTEIN
(Bos
taurus) 		9 / 12 TYR A  26
ASP A  37
PHE A  46
VAL A  55
ILE A  56
TRP A  59
TYR A  82
ILE A  90
PHE A  99
 None
 0.62A 5hw8B-1fkkA:
18.8
5hw8F-1fkkA:
15.0
5hw8G-1fkkA:
18.0		 5hw8B-1fkkA:
45.83
5hw8F-1fkkA:
45.83
5hw8G-1fkkA:
45.83
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5HW8_F_FK5F201_1
(FK506-BINDING
PROTEIN 1)		 1fkk FK506 BINDING
PROTEIN
(Bos
taurus) 		5 / 12 TYR A  26
PHE A  46
TRP A  59
ILE A  90
PHE A  99
 None
 0.92A 5hw8B-1fkkA:
18.8
5hw8F-1fkkA:
15.0
5hw8G-1fkkA:
18.0		 5hw8B-1fkkA:
45.83
5hw8F-1fkkA:
45.83
5hw8G-1fkkA:
45.83
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5HW8_G_FK5G201_2
(FK506-BINDING
PROTEIN 1)		 1fkk FK506 BINDING
PROTEIN
(Bos
taurus) 		9 / 11 TYR A  26
ASP A  37
PHE A  46
VAL A  55
ILE A  56
TRP A  59
TYR A  82
ILE A  91
PHE A  99
 None
 0.62A 5hw8G-1fkkA:
18.0		 5hw8G-1fkkA:
45.83
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5HW8_G_FK5G201_2
(FK506-BINDING
PROTEIN 1)		 1fkk FK506 BINDING
PROTEIN
(Bos
taurus) 		6 / 11 TYR A  26
PHE A  46
TRP A  59
ILE A  90
ILE A  91
PHE A  99
 None
 1.36A 5hw8G-1fkkA:
18.0		 5hw8G-1fkkA:
45.83
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5HW8_H_FK5H201_1
(FK506-BINDING
PROTEIN 1)		 1fkk FK506 BINDING
PROTEIN
(Bos
taurus) 		8 / 8 TYR A  26
ASP A  37
PHE A  46
VAL A  55
ILE A  56
TRP A  59
ILE A  90
PHE A  99
 None
 0.66A 5hw8H-1fkkA:
15.7		 5hw8H-1fkkA:
45.83
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5HWC_A_FK5A201_1
(FK506-BINDING
PROTEIN 1A)		 1fkk FK506 BINDING
PROTEIN
(Bos
taurus) 		10 / 11 TYR A  26
ASP A  37
ARG A  42
PHE A  46
VAL A  55
ILE A  56
TRP A  59
TYR A  82
ILE A  91
PHE A  99
 None
 0.49A 5hwcA-1fkkA:
20.9		 5hwcA-1fkkA:
56.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5Y9Y_A_ACTA409_0
(UNCHARACTERIZED
PROTEIN KDOO)		 1fkk FK506 BINDING
PROTEIN
(Bos
taurus) 		3 / 3 LYS A  44
PRO A  45
LYS A  47
 None
 1.08A 5y9yA-1fkkA:
0.2		 5y9yA-1fkkA:
14.10
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
6MKE_A_FK5A201_0
(PEPTIDYLPROLYL
ISOMERASE)		 1fkk FK506 BINDING
PROTEIN
(Bos
taurus) 		10 / 12 TYR A  26
ASP A  37
ARG A  42
PHE A  46
VAL A  55
ILE A  56
TRP A  59
TYR A  82
ILE A  91
PHE A  99
 None
 0.56A 6mkeA-1fkkA:
19.9
6mkeD-1fkkA:
19.7		 6mkeA-1fkkA:
34.34
6mkeD-1fkkA:
34.34
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
6MKE_A_FK5A201_0
(PEPTIDYLPROLYL
ISOMERASE)		 1fkk FK506 BINDING
PROTEIN
(Bos
taurus) 		6 / 12 TYR A  26
PHE A  46
VAL A  55
TRP A  59
TYR A  82
ILE A  90
 None
 1.38A 6mkeA-1fkkA:
19.9
6mkeD-1fkkA:
19.7		 6mkeA-1fkkA:
34.34
6mkeD-1fkkA:
34.34
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
6MKE_B_FK5B201_0
(PEPTIDYLPROLYL
ISOMERASE)		 1fkk FK506 BINDING
PROTEIN
(Bos
taurus) 		10 / 12 TYR A  26
ASP A  37
ARG A  42
PHE A  46
VAL A  55
ILE A  56
TRP A  59
TYR A  82
ILE A  91
PHE A  99
 None
 0.59A 6mkeB-1fkkA:
19.8
6mkeC-1fkkA:
19.9		 6mkeB-1fkkA:
34.34
6mkeC-1fkkA:
34.34
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
6MKE_B_FK5B201_0
(PEPTIDYLPROLYL
ISOMERASE)		 1fkk FK506 BINDING
PROTEIN
(Bos
taurus) 		6 / 12 TYR A  26
PHE A  46
VAL A  55
TRP A  59
TYR A  82
ILE A  90
 None
 1.39A 6mkeB-1fkkA:
19.8
6mkeC-1fkkA:
19.9		 6mkeB-1fkkA:
34.34
6mkeC-1fkkA:
34.34
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
6MKE_C_FK5C201_1
(PEPTIDYLPROLYL
ISOMERASE)		 1fkk FK506 BINDING
PROTEIN
(Bos
taurus) 		10 / 10 TYR A  26
ASP A  37
ARG A  42
PHE A  46
VAL A  55
ILE A  56
TRP A  59
TYR A  82
ILE A  91
PHE A  99
 None
 0.52A 6mkeC-1fkkA:
19.9		 6mkeC-1fkkA:
34.34
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
6MKE_D_FK5D201_1
(PEPTIDYLPROLYL
ISOMERASE)		 1fkk FK506 BINDING
PROTEIN
(Bos
taurus) 		10 / 10 TYR A  26
ASP A  37
ARG A  42
PHE A  46
VAL A  55
ILE A  56
TRP A  59
TYR A  82
ILE A  91
PHE A  99
 None
 0.49A 6mkeD-1fkkA:
19.7		 6mkeD-1fkkA:
34.34