SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '1fl5'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)

Filter list by:

	DrReposER ID / Desc.	Hit PDBID	Hit Macromolecule	Res. Matches	Interface	HETATM	RMSD	Dali Z-score	Seq. Identity (%)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2ARM_A_OINA401_1 (PHOSPHOLIPASE A2 VRV-PL-VIIIA)	1fl5	ANTIBODY GERMLINE PRECURSOR TO ANTIBODY 28B4 (Homo sapiens)	4 / 7	GLY H 49 TRP H 36 ASP H 95 TYR H 33	None None None SO4 H 301 (-4.3A)	1.20A	2armA-1fl5H: undetectable	2armA-1fl5H: 16.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3RAV_A_RAVA183_1 (FERRITIN LIGHT CHAIN)	1fl5	ANTIBODY GERMLINE PRECURSOR TO ANTIBODY 28B4 (Homo sapiens)	4 / 6	LEU H 48 SER H 60 TYR H 59 ALA H 61	None	1.02A	3ravA-1fl5H: undetectable	3ravA-1fl5H: 24.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4GRK_A_KTRA713_1 (LACTOTRANSFERRIN)	1fl5	ANTIBODY GERMLINE PRECURSOR TO ANTIBODY 28B4 (Homo sapiens)	4 / 5	THR H 822 GLY H 16 VAL H 12 PRO H 14	None	0.90A	4grkA-1fl5H: 0.0	4grkA-1fl5H: 20.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4JX1_B_CAMB502_0 (CAMPHOR 5-MONOOXYGENASE)	1fl5	ANTIBODY GERMLINE PRECURSOR TO ANTIBODY 28B4 (Homo sapiens)	5 / 10	PHE H 122 GLY H 118 THR H 205 VAL H 198 VAL H 207	None	1.20A	4jx1B-1fl5H: undetectable	4jx1B-1fl5H: 19.22

[["DrReposER ID","Desc.","Hit PDB","Hit molecule","Hit organism","Res. no.","Interface","HETATM","RMSD","Z-score","Seq ID"],["2ARM_A_OINA401_1","PHOSPHOLIPASE A2 VRV-PL-VIIIA","1fl5","ANTIBODY GERMLINE PRECURSOR TO ANTIBODY 28B4","Homo sapiens",4,"GLY H  49;TRP H  36;ASP H  95;TYR H  33","None;None;None;SO4 H 301 (-4.3A)","1.20A","2armA-1fl5H:undetectable","2armA-1fl5H:16.89"],["3RAV_A_RAVA183_1","FERRITIN LIGHT CHAIN","1fl5","ANTIBODY GERMLINE PRECURSOR TO ANTIBODY 28B4","Homo sapiens",4,"LEU H  48;SER H  60;TYR H  59;ALA H  61","None","1.02A","3ravA-1fl5H:undetectable","3ravA-1fl5H:24.02"],["4GRK_A_KTRA713_1","LACTOTRANSFERRIN","1fl5","ANTIBODY GERMLINE PRECURSOR TO ANTIBODY 28B4","Homo sapiens",4,"THR H 822;GLY H  16;VAL H  12;PRO H  14","None","0.90A","4grkA-1fl5H:0.0","4grkA-1fl5H:20.59"],["4JX1_B_CAMB502_0","CAMPHOR 5-MONOOXYGENASE","1fl5","ANTIBODY GERMLINE PRECURSOR TO ANTIBODY 28B4","Homo sapiens",5,"PHE H 122;GLY H 118;THR H 205;VAL H 198;VAL H 207","None","1.20A","4jx1B-1fl5H:undetectable","4jx1B-1fl5H:19.22"]]