SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '1flo'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1QHY_A_CLMA888_0
(CHLORAMPHENICOL
PHOSPHOTRANSFERASE)		 1flo FLP RECOMBINASE
(Saccharomyces
cerevisiae) 		4 / 6 LYS A 142
MET A 143
ALA A 146
GLU A 150
 None
 1.12A 1qhyA-1floA:
undetectable		 1qhyA-1floA:
19.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1V54_J_CHDJ3060_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE I
CYTOCHROME C OXIDASE
POLYPEPTIDE
VIIA-HEART)		 1flo FLP RECOMBINASE
(Saccharomyces
cerevisiae) 		4 / 6 ARG A 308
MET A 311
THR A 312
LEU A 315
 None
 0.85A 1v54A-1floA:
0.2
1v54J-1floA:
0.0		 1v54A-1floA:
21.78
1v54J-1floA:
9.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1V55_J_CHDJ3060_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE I
CYTOCHROME C OXIDASE
POLYPEPTIDE
VIIA-HEART)		 1flo FLP RECOMBINASE
(Saccharomyces
cerevisiae) 		5 / 7 ILE A 350
ARG A 308
MET A 311
THR A 312
LEU A 315
 None
 1.10A 1v55A-1floA:
0.1
1v55J-1floA:
0.0		 1v55A-1floA:
21.78
1v55J-1floA:
9.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1V55_P_CHDP4271_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE III
CYTOCHROME C OXIDASE
POLYPEPTIDE
VIIA-HEART)		 1flo FLP RECOMBINASE
(Saccharomyces
cerevisiae) 		4 / 7 LYS A 196
LEU A 275
GLN A 273
LEU A 177
 None
 1.05A 1v55P-1floA:
undetectable
1v55W-1floA:
0.0		 1v55P-1floA:
18.74
1v55W-1floA:
9.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1V55_W_CHDW4060_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE I
CYTOCHROME C OXIDASE
POLYPEPTIDE
VIIA-HEART)		 1flo FLP RECOMBINASE
(Saccharomyces
cerevisiae) 		4 / 8 ILE A 350
MET A 311
THR A 312
LEU A 315
 None
 0.82A 1v55N-1floA:
0.2
1v55W-1floA:
0.0		 1v55N-1floA:
21.78
1v55W-1floA:
9.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2BU8_A_TF4A1379_1
(PYRUVATE
DEHYDROGENASE KINASE
ISOENZYME 2)		 1flo FLP RECOMBINASE
(Saccharomyces
cerevisiae) 		4 / 8 LEU A 147
ILE A 306
ILE A 157
ILE A 161
 None
 0.77A 2bu8A-1floA:
0.0		 2bu8A-1floA:
21.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2DYR_J_CHDJ60_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE
VIIA-HEART
CYTOCHROME C OXIDASE
SUBUNIT 1)		 1flo FLP RECOMBINASE
(Saccharomyces
cerevisiae) 		4 / 6 ARG A 308
MET A 311
THR A 312
LEU A 315
 None
 0.81A 2dyrA-1floA:
0.2
2dyrJ-1floA:
0.0		 2dyrA-1floA:
21.78
2dyrJ-1floA:
9.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2DYR_W_CHDW1060_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE
VIIA-HEART
CYTOCHROME C OXIDASE
SUBUNIT 1)		 1flo FLP RECOMBINASE
(Saccharomyces
cerevisiae) 		4 / 7 ARG A 308
MET A 311
THR A 312
LEU A 315
 None
 0.93A 2dyrN-1floA:
0.2
2dyrW-1floA:
0.0		 2dyrN-1floA:
21.78
2dyrW-1floA:
9.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2DYS_J_CHDJ101_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE
VIIA-HEART
CYTOCHROME C OXIDASE
SUBUNIT 1)		 1flo FLP RECOMBINASE
(Saccharomyces
cerevisiae) 		4 / 6 ARG A 308
MET A 311
THR A 312
LEU A 315
 None
 0.86A 2dysA-1floA:
0.2
2dysJ-1floA:
0.0		 2dysA-1floA:
21.78
2dysJ-1floA:
9.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2DYS_W_CHDW101_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE
VIIA-HEART
CYTOCHROME C OXIDASE
SUBUNIT 1)		 1flo FLP RECOMBINASE
(Saccharomyces
cerevisiae) 		4 / 6 ARG A 308
MET A 311
THR A 312
LEU A 315
 None
 0.97A 2dysN-1floA:
0.2
2dysW-1floA:
0.0		 2dysN-1floA:
21.78
2dysW-1floA:
9.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2EIJ_J_CHDJ60_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE
VIIA-HEART
CYTOCHROME C OXIDASE
SUBUNIT 1)		 1flo FLP RECOMBINASE
(Saccharomyces
cerevisiae) 		4 / 6 ARG A 308
MET A 311
THR A 312
LEU A 315
 None
 0.87A 2eijA-1floA:
0.2
2eijJ-1floA:
0.0		 2eijA-1floA:
21.78
2eijJ-1floA:
9.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2EIJ_W_CHDW1060_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE
VIIA-HEART
CYTOCHROME C OXIDASE
SUBUNIT 1)		 1flo FLP RECOMBINASE
(Saccharomyces
cerevisiae) 		4 / 8 ILE A 350
MET A 311
THR A 312
LEU A 315
 None
 0.81A 2eijN-1floA:
0.2
2eijW-1floA:
0.0		 2eijN-1floA:
21.78
2eijW-1floA:
9.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2EIK_J_CHDJ60_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE
VIIA-HEART
CYTOCHROME C OXIDASE
SUBUNIT 1)		 1flo FLP RECOMBINASE
(Saccharomyces
cerevisiae) 		4 / 7 ARG A 308
MET A 311
THR A 312
LEU A 315
 None
 0.86A 2eikA-1floA:
0.2
2eikJ-1floA:
0.0		 2eikA-1floA:
21.78
2eikJ-1floA:
9.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2EIK_W_CHDW1060_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE
VIIA-HEART
CYTOCHROME C OXIDASE
SUBUNIT 1)		 1flo FLP RECOMBINASE
(Saccharomyces
cerevisiae) 		4 / 8 ILE A 350
MET A 311
THR A 312
LEU A 315
 None
 0.83A 2eikN-1floA:
0.3
2eikW-1floA:
0.0		 2eikN-1floA:
21.78
2eikW-1floA:
9.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2EIL_J_CHDJ60_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE
VIIA-HEART
CYTOCHROME C OXIDASE
SUBUNIT 1)		 1flo FLP RECOMBINASE
(Saccharomyces
cerevisiae) 		4 / 6 ARG A 308
MET A 311
THR A 312
LEU A 315
 None
 0.89A 2eilA-1floA:
0.1
2eilJ-1floA:
0.0		 2eilA-1floA:
21.78
2eilJ-1floA:
9.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2EIM_J_CHDJ60_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE
VIIA-HEART)		 1flo FLP RECOMBINASE
(Saccharomyces
cerevisiae) 		4 / 5 ARG A 308
MET A 311
THR A 312
LEU A 315
 None
 0.90A 2eimJ-1floA:
0.0		 2eimJ-1floA:
9.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2EIM_W_CHDW1060_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE
VIIA-HEART)		 1flo FLP RECOMBINASE
(Saccharomyces
cerevisiae) 		4 / 5 ARG A 308
MET A 311
THR A 312
LEU A 315
 None
 0.91A 2eimW-1floA:
0.0		 2eimW-1floA:
9.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2EIN_J_CHDJ60_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE
VIIA-HEART
CYTOCHROME C OXIDASE
SUBUNIT 1)		 1flo FLP RECOMBINASE
(Saccharomyces
cerevisiae) 		5 / 8 ILE A 350
ARG A 308
MET A 311
THR A 312
LEU A 315
 None
 1.07A 2einA-1floA:
0.0
2einJ-1floA:
0.0		 2einA-1floA:
21.78
2einJ-1floA:
9.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2EIN_W_CHDW1060_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE
VIIA-HEART
CYTOCHROME C OXIDASE
SUBUNIT 1)		 1flo FLP RECOMBINASE
(Saccharomyces
cerevisiae) 		5 / 6 ILE A 350
ARG A 308
MET A 311
THR A 312
LEU A 315
 None
 1.06A 2einN-1floA:
0.0
2einW-1floA:
0.0		 2einN-1floA:
21.78
2einW-1floA:
9.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2PNJ_A_CHDA501_0
(FERROCHELATASE,
MITOCHONDRIAL)		 1flo FLP RECOMBINASE
(Saccharomyces
cerevisiae) 		5 / 12 LEU A 249
LEU A 245
PHE A 248
ILE A 407
VAL A 198
 None
 1.10A 2pnjA-1floA:
undetectable		 2pnjA-1floA:
23.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ZXW_J_CHDJ60_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE 7A1
CYTOCHROME C OXIDASE
SUBUNIT 1)		 1flo FLP RECOMBINASE
(Saccharomyces
cerevisiae) 		4 / 6 ARG A 308
MET A 311
THR A 312
LEU A 315
 None
 0.85A 2zxwA-1floA:
0.1
2zxwJ-1floA:
0.0		 2zxwA-1floA:
21.78
2zxwJ-1floA:
9.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ABK_J_CHDJ60_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE 7A1
CYTOCHROME C OXIDASE
SUBUNIT 1)		 1flo FLP RECOMBINASE
(Saccharomyces
cerevisiae) 		5 / 8 ILE A 350
ARG A 308
MET A 311
THR A 312
LEU A 315
 None
 1.16A 3abkA-1floA:
0.0
3abkJ-1floA:
0.0		 3abkA-1floA:
21.78
3abkJ-1floA:
9.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ABK_W_CHDW1059_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE 7A1
CYTOCHROME C OXIDASE
SUBUNIT 1)		 1flo FLP RECOMBINASE
(Saccharomyces
cerevisiae) 		4 / 5 ILE A 350
ARG A 308
MET A 311
THR A 312
 None
 1.26A 3abkN-1floA:
0.0
3abkW-1floA:
0.0		 3abkN-1floA:
21.78
3abkW-1floA:
9.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ABL_J_CHDJ60_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE 7A1
CYTOCHROME C OXIDASE
SUBUNIT 1)		 1flo FLP RECOMBINASE
(Saccharomyces
cerevisiae) 		4 / 7 ARG A 308
MET A 311
THR A 312
LEU A 315
 None
 0.77A 3ablA-1floA:
0.2
3ablJ-1floA:
0.0		 3ablA-1floA:
21.78
3ablJ-1floA:
9.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ABL_J_CHDJ60_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE 7A1
CYTOCHROME C OXIDASE
SUBUNIT 1)		 1flo FLP RECOMBINASE
(Saccharomyces
cerevisiae) 		4 / 7 ILE A 350
ARG A 308
THR A 312
LEU A 315
 None
 0.89A 3ablA-1floA:
0.2
3ablJ-1floA:
0.0		 3ablA-1floA:
21.78
3ablJ-1floA:
9.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ABL_W_CHDW1060_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE 7A1
CYTOCHROME C OXIDASE
SUBUNIT 1)		 1flo FLP RECOMBINASE
(Saccharomyces
cerevisiae) 		4 / 8 ARG A 308
MET A 311
THR A 312
LEU A 315
 None
 0.81A 3ablN-1floA:
0.1
3ablW-1floA:
0.0		 3ablN-1floA:
21.78
3ablW-1floA:
9.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ABM_J_CHDJ60_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE 7A1
CYTOCHROME C OXIDASE
SUBUNIT 1)		 1flo FLP RECOMBINASE
(Saccharomyces
cerevisiae) 		4 / 6 ARG A 308
MET A 311
THR A 312
LEU A 315
 None
 0.73A 3abmA-1floA:
0.2
3abmJ-1floA:
0.0		 3abmA-1floA:
21.78
3abmJ-1floA:
9.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ABM_W_CHDW1060_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE 7A1
CYTOCHROME C OXIDASE
SUBUNIT 1)		 1flo FLP RECOMBINASE
(Saccharomyces
cerevisiae) 		4 / 8 ILE A 350
MET A 311
THR A 312
LEU A 315
 None
 0.85A 3abmN-1floA:
0.2
3abmW-1floA:
0.0		 3abmN-1floA:
21.78
3abmW-1floA:
9.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ADS_A_IMNA1_1
(PEROXISOME
PROLIFERATOR-ACTIVAT
ED RECEPTOR GAMMA)		 1flo FLP RECOMBINASE
(Saccharomyces
cerevisiae) 		5 / 10 GLU A 410
ILE A 215
CYH A 217
LEU A 274
ILE A 407
 None
 0.94A 3adsA-1floA:
0.9		 3adsA-1floA:
20.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3AG1_J_CHDJ60_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE 7A1)		 1flo FLP RECOMBINASE
(Saccharomyces
cerevisiae) 		4 / 5 ARG A 308
MET A 311
THR A 312
LEU A 315
 None
 0.84A 3ag1J-1floA:
0.0		 3ag1J-1floA:
9.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3AG1_W_CHDW1059_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE 7A1
CYTOCHROME C OXIDASE
SUBUNIT 1)		 1flo FLP RECOMBINASE
(Saccharomyces
cerevisiae) 		5 / 6 ILE A 350
ARG A 308
MET A 311
THR A 312
LEU A 315
 None
 1.14A 3ag1N-1floA:
0.1
3ag1W-1floA:
0.0		 3ag1N-1floA:
21.78
3ag1W-1floA:
9.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3AG2_J_CHDJ60_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE 7A1)		 1flo FLP RECOMBINASE
(Saccharomyces
cerevisiae) 		4 / 5 ARG A 308
MET A 311
THR A 312
LEU A 315
 None
 0.97A 3ag2J-1floA:
0.0		 3ag2J-1floA:
9.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3AG3_J_CHDJ60_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE 7A1
CYTOCHROME C OXIDASE
SUBUNIT 1)		 1flo FLP RECOMBINASE
(Saccharomyces
cerevisiae) 		5 / 7 ILE A 350
ARG A 308
MET A 311
THR A 312
LEU A 315
 None
 1.03A 3ag3A-1floA:
0.2
3ag3J-1floA:
0.0		 3ag3A-1floA:
21.78
3ag3J-1floA:
9.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3AG3_W_CHDW1059_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE 7A1
CYTOCHROME C OXIDASE
SUBUNIT 1)		 1flo FLP RECOMBINASE
(Saccharomyces
cerevisiae) 		4 / 8 ILE A 350
MET A 311
THR A 312
LEU A 315
 None
 0.84A 3ag3N-1floA:
0.0
3ag3W-1floA:
0.0		 3ag3N-1floA:
21.78
3ag3W-1floA:
9.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3AG4_J_CHDJ60_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE 7A1)		 1flo FLP RECOMBINASE
(Saccharomyces
cerevisiae) 		4 / 5 ARG A 308
MET A 311
THR A 312
LEU A 315
 None
 0.74A 3ag4J-1floA:
0.0		 3ag4J-1floA:
9.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ASN_J_CHDJ60_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 7A1)		 1flo FLP RECOMBINASE
(Saccharomyces
cerevisiae) 		4 / 6 ARG A 308
MET A 311
THR A 312
LEU A 315
 None
 0.86A 3asnA-1floA:
undetectable
3asnJ-1floA:
0.0		 3asnA-1floA:
21.78
3asnJ-1floA:
9.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ASN_W_CHDW1059_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 7A1)		 1flo FLP RECOMBINASE
(Saccharomyces
cerevisiae) 		4 / 8 ILE A 350
MET A 311
THR A 312
LEU A 315
 None
 0.82A 3asnN-1floA:
0.2
3asnW-1floA:
0.0		 3asnN-1floA:
21.78
3asnW-1floA:
9.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ASO_J_CHDJ60_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 7A1)		 1flo FLP RECOMBINASE
(Saccharomyces
cerevisiae) 		4 / 6 ARG A 308
MET A 311
THR A 312
LEU A 315
 None
 0.82A 3asoA-1floA:
undetectable
3asoJ-1floA:
0.0		 3asoA-1floA:
21.78
3asoJ-1floA:
9.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ASO_W_CHDW1059_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 7A1)		 1flo FLP RECOMBINASE
(Saccharomyces
cerevisiae) 		5 / 8 ILE A 350
ARG A 308
MET A 311
THR A 312
LEU A 315
 None
 1.07A 3asoN-1floA:
0.3
3asoW-1floA:
0.0		 3asoN-1floA:
21.78
3asoW-1floA:
9.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3CFL_A_5CHA693_1
(LACTOTRANSFERRIN)		 1flo FLP RECOMBINASE
(Saccharomyces
cerevisiae) 		4 / 4 THR A 224
VAL A 219
GLY A 190
THR A 185
 None
 0.70A 3cflA-1floA:
0.0		 3cflA-1floA:
19.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3WG7_W_CHDW101_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)		 1flo FLP RECOMBINASE
(Saccharomyces
cerevisiae) 		4 / 6 ILE A 350
MET A 311
THR A 312
LEU A 315
 None
 0.82A 3wg7N-1floA:
0.2
3wg7W-1floA:
0.0		 3wg7N-1floA:
21.78
3wg7W-1floA:
9.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KY8_A_MTXA603_1
(BIFUNCTIONAL
THYMIDYLATE
SYNTHASE-DIHYDROFOLA
TE REDUCTASE)		 1flo FLP RECOMBINASE
(Saccharomyces
cerevisiae) 		5 / 12 LEU A 287
LYS A 303
SER A 169
ARG A 281
THR A 185
 None
 1.07A 4ky8A-1floA:
undetectable		 4ky8A-1floA:
22.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KY8_D_MTXD603_1
(BIFUNCTIONAL
THYMIDYLATE
SYNTHASE-DIHYDROFOLA
TE REDUCTASE)		 1flo FLP RECOMBINASE
(Saccharomyces
cerevisiae) 		5 / 12 LEU A 287
LYS A 303
SER A 169
ARG A 281
THR A 185
 None
 1.05A 4ky8D-1floA:
undetectable		 4ky8D-1floA:
22.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KY8_E_MTXE603_1
(BIFUNCTIONAL
THYMIDYLATE
SYNTHASE-DIHYDROFOLA
TE REDUCTASE)		 1flo FLP RECOMBINASE
(Saccharomyces
cerevisiae) 		5 / 12 LEU A 287
LYS A 303
SER A 169
ARG A 281
THR A 185
 None
 1.09A 4ky8E-1floA:
undetectable		 4ky8E-1floA:
22.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4MJW_A_ACTA603_0
(CHOLINE OXIDASE)		 1flo FLP RECOMBINASE
(Saccharomyces
cerevisiae) 		3 / 3 ARG A 191
HIS A 305
SER A 193
 None
 0.85A 4mjwA-1floA:
undetectable
4mjwB-1floA:
undetectable		 4mjwA-1floA:
18.63
4mjwB-1floA:
18.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4MJW_B_ACTB603_0
(CHOLINE OXIDASE)		 1flo FLP RECOMBINASE
(Saccharomyces
cerevisiae) 		3 / 3 SER A 193
ARG A 191
HIS A 305
 None
 0.87A 4mjwA-1floA:
undetectable
4mjwB-1floA:
undetectable		 4mjwA-1floA:
18.63
4mjwB-1floA:
18.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4XTA_B_DIFB501_1
(PEROXISOME
PROLIFERATOR-ACTIVAT
ED RECEPTOR GAMMA)		 1flo FLP RECOMBINASE
(Saccharomyces
cerevisiae) 		4 / 8 ILE A 215
CYH A 217
LEU A 274
ILE A 407
 None
 0.88A 4xtaB-1floA:
0.0		 4xtaB-1floA:
20.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4XUM_A_IMNA502_1
(PEROXISOME
PROLIFERATOR-ACTIVAT
ED RECEPTOR GAMMA)		 1flo FLP RECOMBINASE
(Saccharomyces
cerevisiae) 		5 / 7 GLU A 410
ILE A 215
CYH A 217
LEU A 274
ILE A 407
 None
 1.10A 4xumA-1floA:
1.0		 4xumA-1floA:
20.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5B1A_J_CHDJ102_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)		 1flo FLP RECOMBINASE
(Saccharomyces
cerevisiae) 		4 / 7 ILE A 350
MET A 311
THR A 312
LEU A 315
 None
 0.78A 5b1aA-1floA:
0.0
5b1aJ-1floA:
0.0		 5b1aA-1floA:
21.78
5b1aJ-1floA:
9.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5B1B_W_CHDW101_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)		 1flo FLP RECOMBINASE
(Saccharomyces
cerevisiae) 		4 / 7 ILE A 350
MET A 311
THR A 312
LEU A 315
 None
 0.77A 5b1bN-1floA:
0.0
5b1bW-1floA:
0.0		 5b1bN-1floA:
21.78
5b1bW-1floA:
9.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5B3S_J_CHDJ101_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)		 1flo FLP RECOMBINASE
(Saccharomyces
cerevisiae) 		4 / 7 ILE A 350
MET A 311
THR A 312
LEU A 315
 None
 0.79A 5b3sA-1floA:
0.0
5b3sJ-1floA:
0.0		 5b3sA-1floA:
21.78
5b3sJ-1floA:
9.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5B3S_W_CHDW101_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)		 1flo FLP RECOMBINASE
(Saccharomyces
cerevisiae) 		5 / 7 ILE A 350
ARG A 308
MET A 311
THR A 312
LEU A 315
 None
 1.12A 5b3sN-1floA:
0.0
5b3sW-1floA:
0.0		 5b3sN-1floA:
21.78
5b3sW-1floA:
9.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5CYQ_A_T27A601_1
(HIV-1 REVERSE
TRANSCRIPTASE, P66
SUBUNIT)		 1flo FLP RECOMBINASE
(Saccharomyces
cerevisiae) 		5 / 12 LEU A 323
VAL A 358
TYR A 364
PHE A 314
LEU A 315
 None
 1.42A 5cyqA-1floA:
0.0		 5cyqA-1floA:
22.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5IY5_W_CHDW101_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)		 1flo FLP RECOMBINASE
(Saccharomyces
cerevisiae) 		5 / 7 ILE A 350
ARG A 308
MET A 311
THR A 312
LEU A 315
 None
 0.97A 5iy5N-1floA:
0.0
5iy5W-1floA:
0.0		 5iy5N-1floA:
21.78
5iy5W-1floA:
8.98
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5W97_J_CHDJ101_1
(CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)		 1flo FLP RECOMBINASE
(Saccharomyces
cerevisiae) 		4 / 5 ARG A 308
MET A 311
THR A 312
LEU A 315
 None
 1.06A 5w97J-1floA:
0.0		 5w97J-1floA:
9.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5WAU_J_CHDJ101_1
(CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)		 1flo FLP RECOMBINASE
(Saccharomyces
cerevisiae) 		4 / 5 ARG A 308
MET A 311
THR A 312
LEU A 315
 None
 0.77A 5wauJ-1floA:
0.0		 5wauJ-1floA:
9.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5X19_J_CHDJ101_0
(CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)		 1flo FLP RECOMBINASE
(Saccharomyces
cerevisiae) 		4 / 5 ARG A 308
MET A 311
THR A 312
LEU A 315
 None
 0.71A 5x19J-1floA:
0.0		 5x19J-1floA:
9.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5X1B_J_CHDJ101_0
(CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)		 1flo FLP RECOMBINASE
(Saccharomyces
cerevisiae) 		4 / 5 ARG A 308
MET A 311
THR A 312
LEU A 315
 None
 0.85A 5x1bJ-1floA:
0.0		 5x1bJ-1floA:
9.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5X1B_W_CHDW101_0
(CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)		 1flo FLP RECOMBINASE
(Saccharomyces
cerevisiae) 		4 / 5 ARG A 308
MET A 311
THR A 312
LEU A 315
 None
 0.92A 5x1bW-1floA:
0.0		 5x1bW-1floA:
9.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5X1F_J_CHDJ101_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)		 1flo FLP RECOMBINASE
(Saccharomyces
cerevisiae) 		4 / 6 ARG A 308
MET A 311
THR A 312
LEU A 315
 None
 0.77A 5x1fA-1floA:
0.2
5x1fJ-1floA:
0.0		 5x1fA-1floA:
21.78
5x1fJ-1floA:
9.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5X1F_W_CHDW101_0
(CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)		 1flo FLP RECOMBINASE
(Saccharomyces
cerevisiae) 		4 / 5 ARG A 308
MET A 311
THR A 312
LEU A 315
 None
 0.96A 5x1fW-1floA:
0.0		 5x1fW-1floA:
9.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5XDQ_W_CHDW101_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)		 1flo FLP RECOMBINASE
(Saccharomyces
cerevisiae) 		5 / 7 ILE A 350
ARG A 308
MET A 311
THR A 312
LEU A 315
 None
 1.24A 5xdqN-1floA:
0.0
5xdqW-1floA:
0.0		 5xdqN-1floA:
21.78
5xdqW-1floA:
9.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5XDX_J_CHDJ101_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT VIIA-HEART)		 1flo FLP RECOMBINASE
(Saccharomyces
cerevisiae) 		5 / 7 ILE A 350
ARG A 308
MET A 311
THR A 312
LEU A 315
 None
 0.87A 5xdxA-1floA:
0.7
5xdxJ-1floA:
0.0		 5xdxA-1floA:
21.78
5xdxJ-1floA:
9.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5Z86_W_CHDW101_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)		 1flo FLP RECOMBINASE
(Saccharomyces
cerevisiae) 		4 / 6 ILE A 350
MET A 311
THR A 312
LEU A 315
 None
 0.82A 5z86N-1floA:
0.0
5z86W-1floA:
0.0		 5z86N-1floA:
21.78
5z86W-1floA:
9.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ZCO_W_CHDW101_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)		 1flo FLP RECOMBINASE
(Saccharomyces
cerevisiae) 		5 / 6 ILE A 350
ARG A 308
MET A 311
THR A 312
LEU A 315
 None
 1.12A 5zcoN-1floA:
0.0
5zcoW-1floA:
0.0		 5zcoN-1floA:
21.78
5zcoW-1floA:
9.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ZCP_J_CHDJ101_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)		 1flo FLP RECOMBINASE
(Saccharomyces
cerevisiae) 		4 / 7 ILE A 350
MET A 311
THR A 312
LEU A 315
 None
 0.78A 5zcpA-1floA:
0.2
5zcpJ-1floA:
0.0		 5zcpA-1floA:
21.78
5zcpJ-1floA:
9.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ZCP_W_CHDW101_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)		 1flo FLP RECOMBINASE
(Saccharomyces
cerevisiae) 		5 / 8 ILE A 350
ARG A 308
MET A 311
THR A 312
LEU A 315
 None
 1.12A 5zcpN-1floA:
0.0
5zcpW-1floA:
0.0		 5zcpN-1floA:
21.78
5zcpW-1floA:
9.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ZCQ_J_CHDJ101_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)		 1flo FLP RECOMBINASE
(Saccharomyces
cerevisiae) 		4 / 7 ILE A 350
MET A 311
THR A 312
LEU A 315
 None
 0.77A 5zcqA-1floA:
0.1
5zcqJ-1floA:
0.0		 5zcqA-1floA:
21.78
5zcqJ-1floA:
9.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6NKN_J_CHDJ102_0
(CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)		 1flo FLP RECOMBINASE
(Saccharomyces
cerevisiae) 		4 / 5 ARG A 308
MET A 311
THR A 312
LEU A 315
 None
 0.88A 6nknJ-1floA:
0.0		 6nknJ-1floA:
9.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6NMF_J_CHDJ101_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)		 1flo FLP RECOMBINASE
(Saccharomyces
cerevisiae) 		4 / 7 ARG A 308
MET A 311
THR A 312
LEU A 315
 None
 0.86A 6nmfA-1floA:
0.6
6nmfJ-1floA:
0.0		 6nmfA-1floA:
21.78
6nmfJ-1floA:
9.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6NMP_J_CHDJ101_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)		 1flo FLP RECOMBINASE
(Saccharomyces
cerevisiae) 		4 / 7 ARG A 308
MET A 311
THR A 312
LEU A 315
 None
 0.86A 6nmpA-1floA:
0.1
6nmpJ-1floA:
0.0		 6nmpA-1floA:
21.78
6nmpJ-1floA:
9.80