SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '1fmm'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2JFA_B_CCSB417_0
(ESTROGEN RECEPTOR)		 1fmm ACIDIC FIBROBLAST
GROWTH FACTOR
(Notophthalmus
viridescens) 		3 / 3 GLN S  64
LYS S 108
VAL S  23
 None
 0.93A 2jfaB-1fmmS:
undetectable		 2jfaB-1fmmS:
18.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3B9M_A_SALA1200_1
(SERUM ALBUMIN)		 1fmm ACIDIC FIBROBLAST
GROWTH FACTOR
(Notophthalmus
viridescens) 		4 / 5 ILE S 103
TYR S   7
ARG S  27
GLY S  11
 None
 1.16A 3b9mA-1fmmS:
undetectable		 3b9mA-1fmmS:
12.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3MG0_H_BO2H1400_1
(PROTEASOME COMPONENT
PUP1
PROTEASOME COMPONENT
PUP3)		 1fmm ACIDIC FIBROBLAST
GROWTH FACTOR
(Notophthalmus
viridescens) 		5 / 11 THR S 115
GLN S  64
ALA S 121
GLY S 102
THR S 109
 None
 1.16A 3mg0H-1fmmS:
undetectable
3mg0I-1fmmS:
undetectable		 3mg0H-1fmmS:
18.42
3mg0I-1fmmS:
21.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4MWR_A_ZMRA513_2
(NEURAMINIDASE)		 1fmm ACIDIC FIBROBLAST
GROWTH FACTOR
(Notophthalmus
viridescens) 		4 / 5 LEU S  65
ASP S  24
ARG S  16
ILE S  34
 None
 1.45A 4mwrA-1fmmS:
undetectable		 4mwrA-1fmmS:
13.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5L5F_H_BO2H301_1
(PROTEASOME SUBUNIT
BETA TYPE-2
PROTEASOME SUBUNIT
BETA TYPE-3)		 1fmm ACIDIC FIBROBLAST
GROWTH FACTOR
(Notophthalmus
viridescens) 		5 / 12 THR S 115
GLN S  64
ALA S 121
GLY S 102
THR S 109
 None
 1.19A 5l5fH-1fmmS:
undetectable
5l5fI-1fmmS:
undetectable		 5l5fH-1fmmS:
18.42
5l5fI-1fmmS:
21.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5L5F_V_BO2V301_1
(PROTEASOME SUBUNIT
BETA TYPE-2
PROTEASOME SUBUNIT
BETA TYPE-3)		 1fmm ACIDIC FIBROBLAST
GROWTH FACTOR
(Notophthalmus
viridescens) 		5 / 12 THR S 115
GLN S  64
ALA S 121
GLY S 102
THR S 109
 None
 1.19A 5l5fV-1fmmS:
undetectable
5l5fW-1fmmS:
undetectable		 5l5fV-1fmmS:
18.42
5l5fW-1fmmS:
21.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5L66_H_BO2H301_1
(PROTEASOME SUBUNIT
BETA TYPE-2
PROTEASOME SUBUNIT
BETA TYPE-3)		 1fmm ACIDIC FIBROBLAST
GROWTH FACTOR
(Notophthalmus
viridescens) 		5 / 12 THR S 115
GLN S  64
ALA S 121
GLY S 102
THR S 109
 None
 1.17A 5l66H-1fmmS:
undetectable
5l66I-1fmmS:
undetectable		 5l66H-1fmmS:
18.42
5l66I-1fmmS:
21.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5L66_V_BO2V301_1
(PROTEASOME SUBUNIT
BETA TYPE-2
PROTEASOME SUBUNIT
BETA TYPE-3)		 1fmm ACIDIC FIBROBLAST
GROWTH FACTOR
(Notophthalmus
viridescens) 		5 / 12 THR S 115
GLN S  64
ALA S 121
GLY S 102
THR S 109
 None
 1.16A 5l66V-1fmmS:
undetectable
5l66W-1fmmS:
undetectable		 5l66V-1fmmS:
18.42
5l66W-1fmmS:
21.72