SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '1fnh'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ACL_A_REAA502_1
(RETINOIC ACID
RECEPTOR RXR-ALPHA)		 1fnh PROTEIN
(FIBRONECTIN)
(Homo
sapiens) 		5 / 12 GLN A 125
ASN A 167
LEU A 166
PHE A 124
LEU A 163
 None
 0.95A 2aclA-1fnhA:
undetectable
2aclE-1fnhA:
undetectable		 2aclA-1fnhA:
20.44
2aclE-1fnhA:
20.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3B9M_A_SALA1200_1
(SERUM ALBUMIN)		 1fnh PROTEIN
(FIBRONECTIN)
(Homo
sapiens) 		4 / 5 ILE A 240
TYR A 249
ARG A 225
GLY A 242
 None
 1.21A 3b9mA-1fnhA:
undetectable		 3b9mA-1fnhA:
18.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3UCB_B_017B202_1
(PROTEASE)		 1fnh PROTEIN
(FIBRONECTIN)
(Homo
sapiens) 		4 / 7 PRO A 229
ARG A 230
GLY A 212
PRO A 233
 None
 1.36A 3ucbB-1fnhA:
undetectable		 3ucbB-1fnhA:
17.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5UUN_A_ACTA312_0
(GLUTATHIONE
S-TRANSFERASE-LIKE
PROTEIN)		 1fnh PROTEIN
(FIBRONECTIN)
(Homo
sapiens) 		3 / 3 ILE A 240
VAL A 227
PRO A 231
 None
 0.63A 5uunA-1fnhA:
undetectable		 5uunA-1fnhA:
22.29