SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '1fno'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1HK3_A_T44A3003_1
(SERUM ALBUMIN)		 1fno PEPTIDASE T
(Salmonella
enterica) 		3 / 4 LYS A 156
ALA A 153
MET A  45
 None
 1.07A 1hk3A-1fnoA:
0.6		 1hk3A-1fnoA:
20.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1LIN_A_TFPA156_1
(CALMODULIN)		 1fno PEPTIDASE T
(Salmonella
enterica) 		5 / 8 ILE A 217
ILE A 241
GLU A 244
VAL A 301
ILE A 311
 None
 1.36A 1linA-1fnoA:
undetectable		 1linA-1fnoA:
17.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1SG9_C_SAMC303_0
(HEMK PROTEIN)		 1fno PEPTIDASE T
(Salmonella
enterica) 		5 / 12 GLY A  74
ALA A  72
VAL A 195
GLU A 147
ALA A 168
 None
 1.07A 1sg9C-1fnoA:
undetectable		 1sg9C-1fnoA:
22.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1SN5_D_T3D602_1
(TRANSTHYRETIN)		 1fno PEPTIDASE T
(Salmonella
enterica) 		5 / 12 LEU A 333
ALA A 336
VAL A 396
LEU A 371
GLU A 202
 None
 1.06A 1sn5B-1fnoA:
0.0
1sn5D-1fnoA:
0.0		 1sn5B-1fnoA:
16.47
1sn5D-1fnoA:
16.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1SN5_D_T3D602_1
(TRANSTHYRETIN)		 1fno PEPTIDASE T
(Salmonella
enterica) 		5 / 12 LEU A 371
GLU A 202
LEU A 333
ALA A 336
VAL A 396
 None
 1.09A 1sn5B-1fnoA:
0.0
1sn5D-1fnoA:
0.0		 1sn5B-1fnoA:
16.47
1sn5D-1fnoA:
16.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1TW4_A_CHDA130_0
(FATTY ACID-BINDING
PROTEIN)		 1fno PEPTIDASE T
(Salmonella
enterica) 		5 / 12 LEU A 371
LEU A 203
ALA A 336
ILE A 335
ILE A  76
 None
 1.07A 1tw4A-1fnoA:
undetectable		 1tw4A-1fnoA:
15.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1UDU_A_CIAA1003_1
(CGMP-SPECIFIC
3',5'-CYCLIC
PHOSPHODIESTERASE)		 1fno PEPTIDASE T
(Salmonella
enterica) 		5 / 11 ILE A 165
VAL A 167
PHE A 169
LEU A  38
ILE A  50
 None
 1.17A 1uduA-1fnoA:
undetectable		 1uduA-1fnoA:
20.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1XOZ_A_CIAA501_1
(CGMP-SPECIFIC
3',5'-CYCLIC
PHOSPHODIESTERASE)		 1fno PEPTIDASE T
(Salmonella
enterica) 		5 / 12 ILE A 165
VAL A 167
PHE A 169
LEU A  38
ILE A  50
 None
 1.13A 1xozA-1fnoA:
undetectable		 1xozA-1fnoA:
21.74
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2AOU_B_CQAB401_0
(HISTAMINE
N-METHYLTRANSFERASE)		 1fno PEPTIDASE T
(Salmonella
enterica) 		4 / 7 GLY A  87
PRO A  83
ASP A  80
THR A  28
 None
 1.15A 2aouB-1fnoA:
undetectable		 2aouB-1fnoA:
20.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2DPM_A_SAMA300_0
(PROTEIN
(ADENINE-SPECIFIC
METHYLTRANSFERASE
DPNII 1))		 1fno PEPTIDASE T
(Salmonella
enterica) 		5 / 12 GLY A 389
LYS A 392
GLY A 199
GLY A 374
ALA A 393
 None
 1.15A 2dpmA-1fnoA:
undetectable		 2dpmA-1fnoA:
22.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2HDN_B_TACB1888_1
(ELONGATION FACTOR
EF-TU)		 1fno PEPTIDASE T
(Salmonella
enterica) 		4 / 5 SER A  18
ASP A  80
PRO A 171
SER A  27
 None
 1.37A 2hdnA-1fnoA:
0.0
2hdnB-1fnoA:
undetectable
2hdnD-1fnoA:
undetectable		 2hdnA-1fnoA:
12.89
2hdnB-1fnoA:
20.65
2hdnD-1fnoA:
20.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2PO5_A_CHDA501_0
(FERROCHELATASE,
MITOCHONDRIAL)		 1fno PEPTIDASE T
(Salmonella
enterica) 		5 / 12 LEU A  52
ILE A 148
SER A  53
PRO A  26
VAL A  79
 None
 1.19A 2po5A-1fnoA:
undetectable		 2po5A-1fnoA:
21.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BOG_C_DVAC59_0
(6.5 KDA GLYCINE-RICH
ANTIFREEZE PROTEIN)		 1fno PEPTIDASE T
(Salmonella
enterica) 		3 / 3 GLY A 374
GLY A 201
GLY A 199
 None
 0.35A 3bogC-1fnoA:
undetectable		 3bogC-1fnoA:
11.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BOG_D_DVAD10_0
(6.5 KDA GLYCINE-RICH
ANTIFREEZE PROTEIN)		 1fno PEPTIDASE T
(Salmonella
enterica) 		3 / 3 GLY A 389
GLY A 199
GLY A 374
 None
 0.42A 3bogD-1fnoA:
0.0		 3bogD-1fnoA:
11.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3DH0_A_SAMA220_0
(SAM DEPENDENT
METHYLTRANSFERASE)		 1fno PEPTIDASE T
(Salmonella
enterica) 		5 / 12 LEU A  52
VAL A  25
ALA A 168
PHE A 169
THR A 170
 None
 1.28A 3dh0A-1fnoA:
undetectable		 3dh0A-1fnoA:
23.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3EM0_B_CHDB152_0
(ILEAL BILE
ACID-BINDING PROTEIN)		 1fno PEPTIDASE T
(Salmonella
enterica) 		4 / 8 ILE A 215
ASN A 233
VAL A 301
GLY A 302
 None
 0.68A 3em0B-1fnoA:
0.0		 3em0B-1fnoA:
16.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3SO9_A_017A100_1
(HIV-1 PROTEASE)		 1fno PEPTIDASE T
(Salmonella
enterica) 		5 / 8 GLY A 144
ALA A 143
ASP A 141
ASP A 140
GLY A 198
 None
None
ZN  A 501 ( 4.6A)
ZN  A 501 ( 2.5A)
None
 1.39A 3so9A-1fnoA:
undetectable		 3so9A-1fnoA:
14.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3UA1_A_08YA600_1
(CYTOCHROME P450 3A4)		 1fno PEPTIDASE T
(Salmonella
enterica) 		5 / 12 ASP A 183
ILE A 148
ALA A 401
THR A 404
ALA A  72
 None
 1.33A 3ua1A-1fnoA:
undetectable		 3ua1A-1fnoA:
22.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4HB6_A_DXCA75_0
(PPCA)		 1fno PEPTIDASE T
(Salmonella
enterica) 		4 / 8 ILE A 103
LEU A 105
ILE A 129
GLY A 380
 None
 0.84A 4hb6A-1fnoA:
undetectable		 4hb6A-1fnoA:
12.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4K7G_B_ACTB902_0
(3-HYDROXYPROLINE
DEHYDRATSE)		 1fno PEPTIDASE T
(Salmonella
enterica) 		4 / 7 PRO A  26
ASP A 172
TRP A  32
SER A  18
 None
 1.19A 4k7gB-1fnoA:
undetectable		 4k7gB-1fnoA:
23.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4L1A_A_AB1A101_1
(MDR769 HIV-1
PROTEASE)		 1fno PEPTIDASE T
(Salmonella
enterica) 		5 / 11 GLY A 138
ALA A 139
ASP A 140
ILE A 148
VAL A 385
 None
None
ZN  A 501 ( 2.5A)
None
None
 0.93A 4l1aA-1fnoA:
undetectable		 4l1aA-1fnoA:
14.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4PQA_A_X8ZA401_1
(SUCCINYL-DIAMINOPIME
LATE DESUCCINYLASE)		 1fno PEPTIDASE T
(Salmonella
enterica) 		5 / 11 HIS A  78
ASP A 140
GLU A 173
GLU A 174
HIS A 379
 ZN  A 501 (-3.4A)
ZN  A 501 ( 2.5A)
ZN  A 501 ( 4.4A)
ZN  A 502 (-2.6A)
ZN  A 502 (-3.8A)
 0.39A 4pqaA-1fnoA:
31.9		 4pqaA-1fnoA:
24.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4PQA_A_X8ZA401_1
(SUCCINYL-DIAMINOPIME
LATE DESUCCINYLASE)		 1fno PEPTIDASE T
(Salmonella
enterica) 		5 / 11 HIS A  78
ASP A 140
GLU A 174
GLY A 354
HIS A 379
 ZN  A 501 (-3.4A)
ZN  A 501 ( 2.5A)
ZN  A 502 (-2.6A)
SO4  A 600 (-3.5A)
ZN  A 502 (-3.8A)
 0.90A 4pqaA-1fnoA:
31.9		 4pqaA-1fnoA:
24.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4PQA_A_X8ZA401_1
(SUCCINYL-DIAMINOPIME
LATE DESUCCINYLASE)		 1fno PEPTIDASE T
(Salmonella
enterica) 		5 / 11 HIS A  78
GLU A 173
GLU A 174
GLY A 354
HIS A 379
 ZN  A 501 (-3.4A)
ZN  A 501 ( 4.4A)
ZN  A 502 (-2.6A)
SO4  A 600 (-3.5A)
ZN  A 502 (-3.8A)
 0.73A 4pqaA-1fnoA:
31.9		 4pqaA-1fnoA:
24.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QB9_B_PARB500_1
(ENHANCED
INTRACELLULAR
SURVIVAL PROTEIN)		 1fno PEPTIDASE T
(Salmonella
enterica) 		5 / 9 PHE A 187
THR A 170
GLU A 174
ASP A  80
GLY A 178
 None
None
ZN  A 502 (-2.6A)
None
None
 1.46A 4qb9B-1fnoA:
0.0		 4qb9B-1fnoA:
21.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QB9_F_PARF500_1
(ENHANCED
INTRACELLULAR
SURVIVAL PROTEIN)		 1fno PEPTIDASE T
(Salmonella
enterica) 		5 / 11 PHE A 187
THR A 170
GLU A 174
ASP A  80
GLY A 178
 None
None
ZN  A 502 (-2.6A)
None
None
 1.47A 4qb9F-1fnoA:
0.9		 4qb9F-1fnoA:
21.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QVL_B_BO2B201_1
(PROTEASOME SUBUNIT
BETA TYPE-2
PROTEASOME SUBUNIT
BETA TYPE-1)		 1fno PEPTIDASE T
(Salmonella
enterica) 		5 / 11 HIS A 382
THR A 386
THR A 130
THR A 131
GLY A 375
 None
 1.27A 4qvlV-1fnoA:
undetectable
4qvlb-1fnoA:
undetectable		 4qvlV-1fnoA:
20.53
4qvlb-1fnoA:
18.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QVL_N_BO2N201_1
(PROTEASOME SUBUNIT
BETA TYPE-2
PROTEASOME SUBUNIT
BETA TYPE-1)		 1fno PEPTIDASE T
(Salmonella
enterica) 		5 / 11 HIS A 382
THR A 386
THR A 130
THR A 131
GLY A 375
 None
 1.27A 4qvlH-1fnoA:
undetectable
4qvlN-1fnoA:
undetectable		 4qvlH-1fnoA:
20.53
4qvlN-1fnoA:
18.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QVW_B_BO2B201_1
(PROTEASOME SUBUNIT
BETA TYPE-2
PROTEASOME SUBUNIT
BETA TYPE-1)		 1fno PEPTIDASE T
(Salmonella
enterica) 		5 / 11 HIS A 382
THR A 386
THR A 130
THR A 131
GLY A 375
 None
 1.26A 4qvwV-1fnoA:
undetectable
4qvwb-1fnoA:
undetectable		 4qvwV-1fnoA:
20.53
4qvwb-1fnoA:
18.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QVW_N_BO2N201_1
(PROTEASOME SUBUNIT
BETA TYPE-2
PROTEASOME SUBUNIT
BETA TYPE-1)		 1fno PEPTIDASE T
(Salmonella
enterica) 		5 / 11 HIS A 382
THR A 386
THR A 130
THR A 131
GLY A 375
 None
 1.26A 4qvwH-1fnoA:
undetectable
4qvwN-1fnoA:
undetectable		 4qvwH-1fnoA:
20.53
4qvwN-1fnoA:
18.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QW0_B_BO2B201_1
(PROTEASOME SUBUNIT
BETA TYPE-2
PROTEASOME SUBUNIT
BETA TYPE-1)		 1fno PEPTIDASE T
(Salmonella
enterica) 		5 / 11 HIS A 382
THR A 386
THR A 130
THR A 131
GLY A 375
 None
 1.26A 4qw0V-1fnoA:
undetectable
4qw0b-1fnoA:
undetectable		 4qw0V-1fnoA:
20.53
4qw0b-1fnoA:
18.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QW0_N_BO2N201_1
(PROTEASOME SUBUNIT
BETA TYPE-2
PROTEASOME SUBUNIT
BETA TYPE-1)		 1fno PEPTIDASE T
(Salmonella
enterica) 		5 / 11 HIS A 382
THR A 386
THR A 130
THR A 131
GLY A 375
 None
 1.26A 4qw0H-1fnoA:
undetectable
4qw0N-1fnoA:
undetectable		 4qw0H-1fnoA:
20.53
4qw0N-1fnoA:
18.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QW3_B_BO2B201_1
(PROTEASOME SUBUNIT
BETA TYPE-2
PROTEASOME SUBUNIT
BETA TYPE-1)		 1fno PEPTIDASE T
(Salmonella
enterica) 		5 / 11 HIS A 382
THR A 386
THR A 130
THR A 131
GLY A 375
 None
 1.24A 4qw3V-1fnoA:
undetectable
4qw3b-1fnoA:
undetectable		 4qw3V-1fnoA:
20.53
4qw3b-1fnoA:
18.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QW3_N_BO2N201_1
(PROTEASOME SUBUNIT
BETA TYPE-2
PROTEASOME SUBUNIT
BETA TYPE-1)		 1fno PEPTIDASE T
(Salmonella
enterica) 		5 / 11 HIS A 382
THR A 386
THR A 130
THR A 131
GLY A 375
 None
 1.24A 4qw3H-1fnoA:
undetectable
4qw3N-1fnoA:
undetectable		 4qw3H-1fnoA:
20.53
4qw3N-1fnoA:
18.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4R20_A_AERA602_1
(CYTOCHROME P450
FAMILY 17
POLYPEPTIDE 2)		 1fno PEPTIDASE T
(Salmonella
enterica) 		4 / 8 ALA A 393
ILE A 129
GLY A 375
SER A  77
 None
 0.84A 4r20A-1fnoA:
undetectable		 4r20A-1fnoA:
22.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5CR1_A_T44A201_1
(TRANSTHYRETIN)		 1fno PEPTIDASE T
(Salmonella
enterica) 		4 / 5 LYS A 406
LEU A 403
ALA A 405
VAL A  66
 None
 1.05A 5cr1A-1fnoA:
0.0		 5cr1A-1fnoA:
15.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5CZ7_N_BO2N201_1
(PROTEASOME SUBUNIT
BETA TYPE-2
PROTEASOME SUBUNIT
BETA TYPE-1)		 1fno PEPTIDASE T
(Salmonella
enterica) 		5 / 11 HIS A 382
THR A 386
THR A 130
THR A 131
GLY A 375
 None
 1.26A 5cz7H-1fnoA:
undetectable
5cz7N-1fnoA:
undetectable		 5cz7H-1fnoA:
20.53
5cz7N-1fnoA:
18.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5D0X_B_BO2B201_1
(PROTEASOME SUBUNIT
BETA TYPE-2
PROTEASOME SUBUNIT
BETA TYPE-1)		 1fno PEPTIDASE T
(Salmonella
enterica) 		5 / 11 HIS A 382
THR A 386
THR A 130
THR A 131
GLY A 375
 None
 1.26A 5d0xV-1fnoA:
undetectable
5d0xb-1fnoA:
undetectable		 5d0xV-1fnoA:
20.53
5d0xb-1fnoA:
18.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ESG_A_1YNA701_1
(LANOSTEROL 14-ALPHA
DEMETHYLASE)		 1fno PEPTIDASE T
(Salmonella
enterica) 		5 / 12 GLU A 202
TYR A 319
PHE A 282
GLY A 259
THR A 254
 None
SO4  A 600 (-4.8A)
None
None
None
 1.33A 5esgA-1fnoA:
undetectable		 5esgA-1fnoA:
23.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ESK_A_1YNA701_2
(LANOSTEROL 14-ALPHA
DEMETHYLASE)		 1fno PEPTIDASE T
(Salmonella
enterica) 		4 / 4 ALA A  72
PRO A 367
LEU A 333
HIS A 331
 None
 1.37A 5eskA-1fnoA:
0.0		 5eskA-1fnoA:
23.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5F8Y_A_X6XA202_1
(GALNAC/GAL-SPECIFIC
LECTIN)		 1fno PEPTIDASE T
(Salmonella
enterica) 		4 / 8 GLU A 147
GLY A 374
GLY A 375
ASP A 141
 None
None
None
ZN  A 501 ( 4.6A)
 0.78A 5f8yA-1fnoA:
0.0		 5f8yA-1fnoA:
18.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5F8Y_B_X6XB201_1
(GALNAC/GAL-SPECIFIC
LECTIN)		 1fno PEPTIDASE T
(Salmonella
enterica) 		4 / 8 GLU A 147
GLY A 374
GLY A 375
ASP A 141
 None
None
None
ZN  A 501 ( 4.6A)
 0.77A 5f8yB-1fnoA:
0.0		 5f8yB-1fnoA:
18.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5K4P_A_SORA611_0
(PROBABLE
PHOSPHATIDYLETHANOLA
MINE TRANSFERASE
MCR-1)		 1fno PEPTIDASE T
(Salmonella
enterica) 		5 / 6 GLY A 355
THR A 356
TYR A 319
GLY A 358
ASN A 207
 SO4  A 600 (-4.1A)
None
SO4  A 600 (-4.8A)
None
None
 1.33A 5k4pA-1fnoA:
0.5		 5k4pA-1fnoA:
21.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5X7P_A_ACRA1431_1
(GLYCOSIDE HYDROLASE
FAMILY 31
ALPHA-GLUCOSIDASE)		 1fno PEPTIDASE T
(Salmonella
enterica) 		4 / 7 ASP A 196
ASP A 357
GLY A 358
ASN A 370
 ZN  A 501 (-2.1A)
None
None
None
 0.95A 5x7pA-1fnoA:
0.0		 5x7pA-1fnoA:
14.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6C06_D_FI8D1404_1
(DNA-DIRECTED RNA
POLYMERASE SUBUNIT
BETA')		 1fno PEPTIDASE T
(Salmonella
enterica) 		3 / 3 ARG A 292
LYS A 291
ARG A 353
 None
 1.31A 6c06D-1fnoA:
0.0		 6c06D-1fnoA:
undetectable