SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '1fo0'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1D4F_C_ADNC603_2
(S-ADENOSYLHOMOCYSTEI
NE HYDROLASE)		 1fo0 PROTEIN (BM3.3 T
CELL RECEPTOR
ALPHA-CHAIN)
(Mus
musculus) 		4 / 5 THR A  38
THR A  80
HIS A  61
LEU A  46
 None
 1.35A 1d4fC-1fo0A:
undetectable		 1d4fC-1fo0A:
11.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1T86_B_CAMB2422_0
(CYTOCHROME P450-CAM)		 1fo0 PROTEIN (BM3.3 T
CELL RECEPTOR
ALPHA-CHAIN)
(Mus
musculus) 		5 / 9 TYR A  88
THR A  38
LEU A  46
VAL A  44
ASP A  84
 None
 1.42A 1t86B-1fo0A:
undetectable		 1t86B-1fo0A:
14.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2A1N_B_CAMB2422_0
(CYTOCHROME P450-CAM)		 1fo0 PROTEIN (BM3.3 T
CELL RECEPTOR
ALPHA-CHAIN)
(Mus
musculus) 		5 / 9 TYR A  88
THR A  38
LEU A  46
VAL A  44
ASP A  84
 None
 1.49A 2a1nB-1fo0A:
0.0		 2a1nB-1fo0A:
14.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2PYM_A_1UNA1001_3
(PROTEASE RETROPEPSIN)		 1fo0 PROTEIN (BM3.3 T
CELL RECEPTOR
BETA-CHAIN)
(Mus
musculus) 		3 / 3 ASP B  97
ASN B 103
THR B  93
 None
 0.72A 2pymB-1fo0B:
0.0		 2pymB-1fo0B:
21.74
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2X7H_A_PFNA1375_1
(ZINC-BINDING ALCOHOL
DEHYDROGENASE
DOMAIN-CONTAINING
PROTEIN 2)		 1fo0 PROTEIN (BM3.3 T
CELL RECEPTOR
ALPHA-CHAIN)
PROTEIN (BM3.3 T
CELL RECEPTOR
BETA-CHAIN)
(Mus
musculus) 		4 / 5 SER A  30
TYR A  52
PHE A  31
VAL B  99
 None
 1.46A 2x7hA-1fo0A:
undetectable		 2x7hA-1fo0A:
16.01
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2X7H_B_PFNB1372_1
(ZINC-BINDING ALCOHOL
DEHYDROGENASE
DOMAIN-CONTAINING
PROTEIN 2)		 1fo0 PROTEIN (BM3.3 T
CELL RECEPTOR
ALPHA-CHAIN)
PROTEIN (BM3.3 T
CELL RECEPTOR
BETA-CHAIN)
(Mus
musculus) 		4 / 5 SER A  30
TYR A  52
PHE A  31
VAL B  99
 None
 1.46A 2x7hB-1fo0A:
undetectable		 2x7hB-1fo0A:
16.01
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3B0W_A_DGXA1_2
(NUCLEAR RECEPTOR
ROR-GAMMA)		 1fo0 PROTEIN (BM3.3 T
CELL RECEPTOR
BETA-CHAIN)
(Mus
musculus) 		3 / 3 TRP B  34
VAL B  13
ARG B  15
 None
 0.93A 3b0wA-1fo0B:
0.0		 3b0wA-1fo0B:
15.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4EK1_B_CAMB502_0
(CAMPHOR
5-MONOOXYGENASE)		 1fo0 PROTEIN (BM3.3 T
CELL RECEPTOR
ALPHA-CHAIN)
(Mus
musculus) 		5 / 9 TYR A  88
THR A  38
LEU A  46
VAL A  44
ASP A  84
 None
 1.43A 4ek1B-1fo0A:
0.0		 4ek1B-1fo0A:
14.47