SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '1foe'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1DTL_A_BEPA206_1
(CARDIAC TROPONIN C)		 1foe T-LYMPHOMA INVASION
AND METASTASIS
INDUCING PROTEIN 1
(Mus
musculus) 		4 / 8 MET A1334
PRO A1336
GLU A1258
ASP A1261
 None
 1.19A 1dtlA-1foeA:
undetectable		 1dtlA-1foeA:
16.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1MZ9_D_VDYD1001_2
(CARTILAGE OLIGOMERIC
MATRIX PROTEIN)		 1foe T-LYMPHOMA INVASION
AND METASTASIS
INDUCING PROTEIN 1
(Mus
musculus) 		3 / 3 LEU A1041
VAL A1044
LEU A1048
 None
 0.51A 1mz9B-1foeA:
undetectable		 1mz9B-1foeA:
9.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1WRK_B_TFPB203_1
(TROPONIN C, SLOW
SKELETAL AND CARDIAC
MUSCLES)		 1foe T-LYMPHOMA INVASION
AND METASTASIS
INDUCING PROTEIN 1
(Mus
musculus) 		4 / 5 PHE A1098
LEU A1048
PHE A1139
MET A1224
 None
 1.08A 1wrkB-1foeA:
undetectable		 1wrkB-1foeA:
12.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1WRK_B_TFPB203_1
(TROPONIN C, SLOW
SKELETAL AND CARDIAC
MUSCLES)		 1foe T-LYMPHOMA INVASION
AND METASTASIS
INDUCING PROTEIN 1
(Mus
musculus) 		4 / 5 PHE A1294
PHE A1296
MET A1264
SER A1143
 None
 1.29A 1wrkB-1foeA:
undetectable		 1wrkB-1foeA:
12.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1WRL_A_TFPA204_1
(TROPONIN C, SLOW
SKELETAL AND CARDIAC
MUSCLES)		 1foe T-LYMPHOMA INVASION
AND METASTASIS
INDUCING PROTEIN 1
(Mus
musculus) 		4 / 7 PHE A1098
LEU A1048
PHE A1139
MET A1224
 None
 1.10A 1wrlA-1foeA:
undetectable
1wrlB-1foeA:
undetectable		 1wrlA-1foeA:
12.84
1wrlB-1foeA:
12.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1WRL_C_TFPC208_1
(TROPONIN C, SLOW
SKELETAL AND CARDIAC
MUSCLES)		 1foe T-LYMPHOMA INVASION
AND METASTASIS
INDUCING PROTEIN 1
(Mus
musculus) 		4 / 5 PHE A1098
LEU A1048
PHE A1139
MET A1224
 None
 1.06A 1wrlC-1foeA:
undetectable		 1wrlC-1foeA:
12.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1WRL_E_TFPE212_1
(TROPONIN C, SLOW
SKELETAL AND CARDIAC
MUSCLES)		 1foe T-LYMPHOMA INVASION
AND METASTASIS
INDUCING PROTEIN 1
(Mus
musculus) 		4 / 7 PHE A1098
LEU A1048
PHE A1139
MET A1224
 None
 1.12A 1wrlE-1foeA:
undetectable		 1wrlE-1foeA:
12.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1Y7I_B_SALB503_1
(SALICYLIC
ACID-BINDING PROTEIN
2)		 1foe T-LYMPHOMA INVASION
AND METASTASIS
INDUCING PROTEIN 1
(Mus
musculus) 		5 / 10 SER A1131
LEU A1128
PHE A1132
TYR A1196
LEU A1048
 None
 1.09A 1y7iB-1foeA:
undetectable		 1y7iB-1foeA:
25.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2AOX_A_THAA400_1
(HISTAMINE
N-METHYLTRANSFERASE)		 1foe T-LYMPHOMA INVASION
AND METASTASIS
INDUCING PROTEIN 1
(Mus
musculus) 		4 / 8 PHE A1132
GLU A1052
GLN A1095
TYR A1142
 None
 1.37A 2aoxA-1foeA:
undetectable		 2aoxA-1foeA:
21.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2JJ8_C_AZZC1211_1
(DEOXYNUCLEOSIDE
KINASE)		 1foe T-LYMPHOMA INVASION
AND METASTASIS
INDUCING PROTEIN 1
(Mus
musculus) 		5 / 12 ILE A1187
VAL A1193
LEU A1194
GLN A1235
ALA A1147
 None
 1.48A 2jj8C-1foeA:
0.9		 2jj8C-1foeA:
23.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3CR4_X_PNTX101_0
(PROTEIN S100-B)		 1foe T-LYMPHOMA INVASION
AND METASTASIS
INDUCING PROTEIN 1
(Mus
musculus) 		3 / 3 CYH A1146
HIS A1149
PHE A1145
 None
 1.07A 3cr4X-1foeA:
1.0		 3cr4X-1foeA:
13.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3GWU_A_SREA801_1
(TRANSPORTER)		 1foe T-LYMPHOMA INVASION
AND METASTASIS
INDUCING PROTEIN 1
(Mus
musculus) 		5 / 12 LEU A1182
LEU A1156
TYR A1066
ALA A1159
ASP A1170
 None
 1.35A 3gwuA-1foeA:
1.4		 3gwuA-1foeA:
21.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3LM8_B_VIBB223_1
(THIAMINE
PYROPHOSPHOKINASE)		 1foe T-LYMPHOMA INVASION
AND METASTASIS
INDUCING PROTEIN 1
(Mus
musculus) 		4 / 7 TYR A1066
LEU A1084
LEU A1156
SER A1184
 None
 1.06A 3lm8B-1foeA:
undetectable
3lm8D-1foeA:
undetectable		 3lm8B-1foeA:
19.37
3lm8D-1foeA:
19.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3V1N_A_BEZA288_0
(2-HYDROXY-6-OXO-6-PH
ENYLHEXA-2,4-DIENOAT
E HYDROLASE)		 1foe T-LYMPHOMA INVASION
AND METASTASIS
INDUCING PROTEIN 1
(Mus
musculus) 		5 / 8 GLY A1130
GLY A1129
SER A1127
GLY A1105
LEU A1049
 None
 1.40A 3v1nA-1foeA:
undetectable		 3v1nA-1foeA:
21.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4EJG_A_NCTA501_1
(CYTOCHROME P450 2A13)		 1foe T-LYMPHOMA INVASION
AND METASTASIS
INDUCING PROTEIN 1
(Mus
musculus) 		4 / 7 PHE A1098
PHE A1139
ALA A1136
THR A1223
 None
 1.01A 4ejgA-1foeA:
0.0		 4ejgA-1foeA:
23.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4JEC_B_478B401_3
(HIV-1 PROTEASE)		 1foe T-LYMPHOMA INVASION
AND METASTASIS
INDUCING PROTEIN 1
(Mus
musculus) 		3 / 3 ASP A1039
LEU A1206
VAL A1124
 None
 0.68A 4jecB-1foeA:
0.0		 4jecB-1foeA:
12.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5TE8_C_08JC602_1
(CYTOCHROME P450 3A4)		 1foe T-LYMPHOMA INVASION
AND METASTASIS
INDUCING PROTEIN 1
(Mus
musculus) 		4 / 7 LEU A1269
ALA A1293
ILE A1237
LEU A1267
 None
 0.86A 5te8C-1foeA:
0.0		 5te8C-1foeA:
22.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VC0_A_RITA602_1
(CYTOCHROME P450 3A4)		 1foe T-LYMPHOMA INVASION
AND METASTASIS
INDUCING PROTEIN 1
(Mus
musculus) 		5 / 12 ASP A1327
PHE A1331
ILE A1335
ALA A1299
ILE A1249
 None
 1.20A 5vc0A-1foeA:
0.0		 5vc0A-1foeA:
22.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6FGC_A_D95A816_0
(GEPHYRIN)		 1foe T-LYMPHOMA INVASION
AND METASTASIS
INDUCING PROTEIN 1
(Mus
musculus) 		5 / 11 ASP A1261
ILE A1249
LEU A1248
LEU A1267
ILE A1393
 None
 1.35A 6fgcA-1foeA:
undetectable		 6fgcA-1foeA:
12.47