SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '1fon'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1BDW_A_DVAA6_0
(GRAMICIDIN A)		 1fon PROCARBOXYPEPTIDASE
A-S6
(Bos
taurus) 		3 / 3 ALA A  41
VAL A  79
TRP A  83
 None
 0.92A 1bdwA-1fonA:
undetectable
1bdwB-1fonA:
undetectable		 1bdwA-1fonA:
6.10
1bdwB-1fonA:
6.10
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1IGX_A_EPAA700_2
(PROSTAGLANDIN
ENDOPEROXIDE H
SYNTHASE-1)		 1fon PROCARBOXYPEPTIDASE
A-S6
(Bos
taurus) 		4 / 8 VAL A  14
VAL A  97
ILE A  70
LEU A  16
 None
 0.85A 1igxA-1fonA:
undetectable		 1igxA-1fonA:
16.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1W5U_B_DVAB6_0
(GRAMICIDIN D)		 1fon PROCARBOXYPEPTIDASE
A-S6
(Bos
taurus) 		3 / 3 TRP A  12
ALA A 112
VAL A 109
 None
 0.97A 1w5uA-1fonA:
undetectable
1w5uB-1fonA:
undetectable		 1w5uA-1fonA:
6.10
1w5uB-1fonA:
6.10
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3SUE_D_SUED1201_2
(NS3 PROTEASE, NS4A
PROTEIN)		 1fon PROCARBOXYPEPTIDASE
A-S6
(Bos
taurus) 		3 / 3 TYR A 128
LEU A  63
LYS A 144
 None
 0.78A 3sueD-1fonA:
9.0		 3sueD-1fonA:
25.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4GC9_A_ACTA402_0
(DIMETHYLADENOSINE
TRANSFERASE 1,
MITOCHONDRIAL)		 1fon PROCARBOXYPEPTIDASE
A-S6
(Bos
taurus) 		3 / 3 LYS A  20
TYR A  18
ARG A  49
 None
 1.15A 4gc9A-1fonA:
undetectable		 4gc9A-1fonA:
20.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5F8Y_A_X6XA202_1
(GALNAC/GAL-SPECIFIC
LECTIN)		 1fon PROCARBOXYPEPTIDASE
A-S6
(Bos
taurus) 		4 / 8 GLU A  67
GLY A 139
GLY A 138
VAL A  54
 None
 0.77A 5f8yA-1fonA:
undetectable		 5f8yA-1fonA:
19.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5JMN_C_FUAC1101_1
(MULTIDRUG EFFLUX
PUMP SUBUNIT ACRB)		 1fon PROCARBOXYPEPTIDASE
A-S6
(Bos
taurus) 		3 / 3 VAL A 168
HIS A 157
VAL A 153
 None
 0.66A 5jmnC-1fonA:
0.0		 5jmnC-1fonA:
12.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5O96_C_SAMC501_0
(RIBOSOMAL RNA SMALL
SUBUNIT
METHYLTRANSFERASE E)		 1fon PROCARBOXYPEPTIDASE
A-S6
(Bos
taurus) 		4 / 7 GLY A 182
GLY A 185
THR A 221
ALA A 175
 None
 0.76A 5o96C-1fonA:
undetectable		 5o96C-1fonA:
20.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6AG0_A_ACRA606_0
(ALPHA-AMYLASE)		 1fon PROCARBOXYPEPTIDASE
A-S6
(Bos
taurus) 		5 / 7 GLY A 185
GLY A 189
PRO A 190
GLY A  30
GLY A  29
 None
 1.06A 6ag0A-1fonA:
undetectable		 6ag0A-1fonA:
16.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6DLZ_A_CYZA1302_0
(GLUTAMATE RECEPTOR
2,VOLTAGE-DEPENDENT
CALCIUM CHANNEL
GAMMA-2 SUBUNIT)		 1fon PROCARBOXYPEPTIDASE
A-S6
(Bos
taurus) 		5 / 10 LEU A 191
ASP A  93
ILE A 129
SER A 187
GLY A 185
 None
 1.21A 6dlzA-1fonA:
undetectable
6dlzD-1fonA:
undetectable		 6dlzA-1fonA:
15.65
6dlzD-1fonA:
15.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6DLZ_C_CYZC1302_0
(GLUTAMATE RECEPTOR
2,VOLTAGE-DEPENDENT
CALCIUM CHANNEL
GAMMA-2 SUBUNIT)		 1fon PROCARBOXYPEPTIDASE
A-S6
(Bos
taurus) 		5 / 10 ILE A 129
SER A 187
GLY A 185
LEU A 191
ASP A  93
 None
 1.21A 6dlzB-1fonA:
undetectable
6dlzC-1fonA:
undetectable		 6dlzB-1fonA:
15.65
6dlzC-1fonA:
15.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6DM0_B_CYZB1302_0
(GLUTAMATE RECEPTOR
2,VOLTAGE-DEPENDENT
CALCIUM CHANNEL
GAMMA-2 SUBUNIT)		 1fon PROCARBOXYPEPTIDASE
A-S6
(Bos
taurus) 		5 / 10 LEU A 191
ASP A  93
ILE A 129
SER A 187
GLY A 185
 None
 1.30A 6dm0B-1fonA:
undetectable
6dm0C-1fonA:
undetectable		 6dm0B-1fonA:
15.65
6dm0C-1fonA:
15.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6DM1_A_CYZA1302_0
(GLUTAMATE RECEPTOR
2,VOLTAGE-DEPENDENT
CALCIUM CHANNEL
GAMMA-2 SUBUNIT)		 1fon PROCARBOXYPEPTIDASE
A-S6
(Bos
taurus) 		5 / 10 LEU A 191
ASP A  93
ILE A 129
SER A 187
GLY A 185
 None
 1.22A 6dm1A-1fonA:
undetectable
6dm1D-1fonA:
undetectable		 6dm1A-1fonA:
15.65
6dm1D-1fonA:
15.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6DM1_C_CYZC1302_0
(GLUTAMATE RECEPTOR
2,VOLTAGE-DEPENDENT
CALCIUM CHANNEL
GAMMA-2 SUBUNIT)		 1fon PROCARBOXYPEPTIDASE
A-S6
(Bos
taurus) 		5 / 10 ILE A 129
SER A 187
GLY A 185
LEU A 191
ASP A  93
 None
 1.22A 6dm1B-1fonA:
undetectable
6dm1C-1fonA:
undetectable		 6dm1B-1fonA:
15.65
6dm1C-1fonA:
15.65