SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '1fou'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)

Filter list by:

	DrReposER ID / Desc.	Hit PDBID	Hit Macromolecule	Res. Matches	Interface	HETATM	RMSD	Dali Z-score	Seq. Identity (%)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3RQW_I_ACHI323_0 (ELIC PENTAMERIC LIGAND GATED ION CHANNEL FROM ERWINIA CHRYSANTHEMI)	1fou	UPPER COLLAR PROTEIN (Bacillus virus phi29)	4 / 8	PHE A 65 ILE A 57 GLU A 54 LEU A 44	None	1.05A	3rqwI-1fouA: undetectable 3rqwJ-1fouA: undetectable	3rqwI-1fouA: 21.37 3rqwJ-1fouA: 21.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5JSD_A_1GNA615_1 (PHIAB6 TAILSPIKE)	1fou	UPPER COLLAR PROTEIN (Bacillus virus phi29)	3 / 3	TYR A 109 TYR A 87 GLN A 89	None	1.14A	5jsdA-1fouA: 0.0 5jsdB-1fouA: 0.0	5jsdA-1fouA: 19.71 5jsdB-1fouA: 19.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5JSD_B_1GNB606_1 (PHIAB6 TAILSPIKE)	1fou	UPPER COLLAR PROTEIN (Bacillus virus phi29)	3 / 3	TYR A 109 TYR A 87 GLN A 89	None	1.14A	5jsdB-1fouA: 0.0 5jsdC-1fouA: 0.0	5jsdB-1fouA: 19.71 5jsdC-1fouA: 19.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5N0O_A_SAMA501_1 (PEPTIDE N-METHYLTRANSFERASE)	1fou	UPPER COLLAR PROTEIN (Bacillus virus phi29)	3 / 3	ALA A 35 GLN A 59 THR A 130	None	0.60A	5n0oA-1fouA: undetectable	5n0oA-1fouA: 20.24

[["DrReposER ID","Desc.","Hit PDB","Hit molecule","Hit organism","Res. no.","Interface","HETATM","RMSD","Z-score","Seq ID"],["3RQW_I_ACHI323_0","ELIC PENTAMERIC LIGAND GATED ION CHANNEL FROM ERWINIA CHRYSANTHEMI","1fou","UPPER COLLAR PROTEIN","Bacillus virus phi29",4,"PHE A  65;ILE A  57;GLU A  54;LEU A  44","None","1.05A","3rqwI-1fouA:undetectable;3rqwJ-1fouA:undetectable","3rqwI-1fouA:21.37;3rqwJ-1fouA:21.37"],["5JSD_A_1GNA615_1","PHIAB6 TAILSPIKE;PHIAB6 TAILSPIKE","1fou","UPPER COLLAR PROTEIN","Bacillus virus phi29",3,"TYR A 109;TYR A  87;GLN A  89","None","1.14A","5jsdA-1fouA:0.0;5jsdB-1fouA:0.0","5jsdA-1fouA:19.71;5jsdB-1fouA:19.71"],["5JSD_B_1GNB606_1","PHIAB6 TAILSPIKE;PHIAB6 TAILSPIKE","1fou","UPPER COLLAR PROTEIN","Bacillus virus phi29",3,"TYR A 109;TYR A  87;GLN A  89","None","1.14A","5jsdB-1fouA:0.0;5jsdC-1fouA:0.0","5jsdB-1fouA:19.71;5jsdC-1fouA:19.71"],["5N0O_A_SAMA501_1","PEPTIDE N-METHYLTRANSFERASE","1fou","UPPER COLLAR PROTEIN","Bacillus virus phi29",3,"ALA A  35;GLN A  59;THR A 130","None","0.60A","5n0oA-1fouA:undetectable","5n0oA-1fouA:20.24"]]