SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '1fp2'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1FPQ_A_SAMA1699_0
(ISOLIQUIRITIGENIN
2'-O-METHYLTRANSFERA
SE)		 1fp2 ISOFLAVONE
O-METHYLTRANSFERASE
(Medicago
sativa) 		6 / 10 GLY A 196
ASP A 219
VAL A 223
ASP A 239
ASN A 258
TRP A 259
 SAH  A1699 (-3.8A)
SAH  A1699 (-2.9A)
None
SAH  A1699 (-3.8A)
HMO  A2000 (-3.1A)
None
 0.26A 1fpqA-1fp2A:
22.0		 1fpqA-1fp2A:
29.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1MT1_C_AG2C7004_1
(PYRUVOYL-DEPENDENT
ARGININE
DECARBOXYLASE BETA
CHAIN
PYRUVOYL-DEPENDENT
ARGININE
DECARBOXYLASE ALPHA
CHAIN)		 1fp2 ISOFLAVONE
O-METHYLTRANSFERASE
(Medicago
sativa) 		4 / 6 ALA A 167
LEU A 123
LEU A 154
LEU A 314
 None
HMO  A2000 (-3.8A)
None
None
 0.89A 1mt1D-1fp2A:
undetectable
1mt1E-1fp2A:
undetectable		 1mt1D-1fp2A:
13.07
1mt1E-1fp2A:
9.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1NHZ_A_486A800_1
(GLUCOCORTICOID
RECEPTOR)		 1fp2 ISOFLAVONE
O-METHYLTRANSFERASE
(Medicago
sativa) 		5 / 12 MET A  75
LEU A  78
GLY A  82
LEU A 103
LEU A  96
 None
 1.26A 1nhzA-1fp2A:
undetectable		 1nhzA-1fp2A:
20.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1QZZ_A_SAMA635_0
(ACLACINOMYCIN-10-HYD
ROXYLASE)		 1fp2 ISOFLAVONE
O-METHYLTRANSFERASE
(Medicago
sativa) 		6 / 12 GLY A 196
GLY A 197
GLY A 198
ASP A 239
ASN A 258
TRP A 259
 SAH  A1699 (-3.8A)
SAH  A1699 ( 4.2A)
SAH  A1699 ( 3.9A)
SAH  A1699 (-3.8A)
HMO  A2000 (-3.1A)
None
 0.58A 1qzzA-1fp2A:
26.3		 1qzzA-1fp2A:
26.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1QZZ_A_SAMA635_0
(ACLACINOMYCIN-10-HYD
ROXYLASE)		 1fp2 ISOFLAVONE
O-METHYLTRANSFERASE
(Medicago
sativa) 		6 / 12 TRP A 151
GLY A 196
GLY A 197
GLY A 198
ASP A 239
TRP A 259
 SAH  A1699 ( 3.8A)
SAH  A1699 (-3.8A)
SAH  A1699 ( 4.2A)
SAH  A1699 ( 3.9A)
SAH  A1699 (-3.8A)
None
 0.82A 1qzzA-1fp2A:
26.3		 1qzzA-1fp2A:
26.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1XDS_A_SAMA5635_0
(PROTEIN RDMB)		 1fp2 ISOFLAVONE
O-METHYLTRANSFERASE
(Medicago
sativa) 		7 / 12 TRP A 151
GLY A 196
GLY A 197
GLY A 198
ASP A 239
ASN A 258
TRP A 259
 SAH  A1699 ( 3.8A)
SAH  A1699 (-3.8A)
SAH  A1699 ( 4.2A)
SAH  A1699 ( 3.9A)
SAH  A1699 (-3.8A)
HMO  A2000 (-3.1A)
None
 0.65A 1xdsA-1fp2A:
29.5		 1xdsA-1fp2A:
26.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1XDS_A_SAMA5635_0
(PROTEIN RDMB)		 1fp2 ISOFLAVONE
O-METHYLTRANSFERASE
(Medicago
sativa) 		5 / 12 TRP A 151
GLY A 197
ASP A 239
ASN A 258
TRP A 259
 SAH  A1699 ( 3.8A)
SAH  A1699 ( 4.2A)
SAH  A1699 (-3.8A)
HMO  A2000 (-3.1A)
None
 0.87A 1xdsA-1fp2A:
29.5		 1xdsA-1fp2A:
26.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1XDS_B_SAMB9635_0
(PROTEIN RDMB)		 1fp2 ISOFLAVONE
O-METHYLTRANSFERASE
(Medicago
sativa) 		7 / 12 TRP A 151
GLY A 196
GLY A 197
GLY A 198
ASP A 239
ASN A 258
TRP A 259
 SAH  A1699 ( 3.8A)
SAH  A1699 (-3.8A)
SAH  A1699 ( 4.2A)
SAH  A1699 ( 3.9A)
SAH  A1699 (-3.8A)
HMO  A2000 (-3.1A)
None
 0.58A 1xdsB-1fp2A:
29.1		 1xdsB-1fp2A:
26.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2UYQ_A_SAMA1311_0
(HYPOTHETICAL PROTEIN
ML2640)		 1fp2 ISOFLAVONE
O-METHYLTRANSFERASE
(Medicago
sativa) 		4 / 7 GLY A 198
ASP A 219
VAL A 223
ASP A 239
 SAH  A1699 ( 3.9A)
SAH  A1699 (-2.9A)
None
SAH  A1699 (-3.8A)
 0.71A 2uyqA-1fp2A:
10.3		 2uyqA-1fp2A:
18.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2XFH_A_CL6A1414_1
(ERYTHROMYCIN B/D
C-12 HYDROXYLASE)		 1fp2 ISOFLAVONE
O-METHYLTRANSFERASE
(Medicago
sativa) 		5 / 8 LEU A 341
ILE A 175
LEU A 179
THR A 285
LEU A 347
 None
 1.49A 2xfhA-1fp2A:
0.0		 2xfhA-1fp2A:
20.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3I5U_A_SAMA401_0
(O-METHYLTRANSFERASE)		 1fp2 ISOFLAVONE
O-METHYLTRANSFERASE
(Medicago
sativa) 		6 / 12 TRP A 151
PHE A 164
MET A 168
GLY A 197
GLY A 198
TRP A 259
 SAH  A1699 ( 3.8A)
HMO  A2000 (-4.9A)
HMO  A2000 ( 4.0A)
SAH  A1699 ( 4.2A)
SAH  A1699 ( 3.9A)
None
 0.63A 3i5uA-1fp2A:
29.6		 3i5uA-1fp2A:
25.34
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3I5U_A_SAMA401_0
(O-METHYLTRANSFERASE)		 1fp2 ISOFLAVONE
O-METHYLTRANSFERASE
(Medicago
sativa) 		5 / 12 TRP A 151
PHE A 164
MET A 168
GLY A 198
TRP A 259
 SAH  A1699 ( 3.8A)
HMO  A2000 (-4.9A)
HMO  A2000 ( 4.0A)
SAH  A1699 ( 3.9A)
None
 0.98A 3i5uA-1fp2A:
29.6		 3i5uA-1fp2A:
25.34
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3I5U_B_SAMB401_0
(O-METHYLTRANSFERASE)		 1fp2 ISOFLAVONE
O-METHYLTRANSFERASE
(Medicago
sativa) 		5 / 12 TRP A 151
MET A 168
GLY A 197
GLY A 198
TRP A 259
 SAH  A1699 ( 3.8A)
HMO  A2000 ( 4.0A)
SAH  A1699 ( 4.2A)
SAH  A1699 ( 3.9A)
None
 0.62A 3i5uB-1fp2A:
29.7		 3i5uB-1fp2A:
25.34
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3IHT_A_SAMA200_0
(S-ADENOSYL-L-METHION
INE METHYL
TRANSFERASE)		 1fp2 ISOFLAVONE
O-METHYLTRANSFERASE
(Medicago
sativa) 		5 / 12 GLY A 196
GLY A 198
GLY A 200
THR A 202
ASP A 239
 SAH  A1699 (-3.8A)
SAH  A1699 ( 3.9A)
None
None
SAH  A1699 (-3.8A)
 1.04A 3ihtA-1fp2A:
7.4		 3ihtA-1fp2A:
17.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3IJD_A_C2FA314_0
(UNCHARACTERIZED
PROTEIN)		 1fp2 ISOFLAVONE
O-METHYLTRANSFERASE
(Medicago
sativa) 		5 / 12 LEU A 268
VAL A 275
GLY A 282
ILE A 192
LEU A 252
 None
 1.01A 3ijdA-1fp2A:
undetectable		 3ijdA-1fp2A:
21.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3IJD_B_C2FB314_0
(UNCHARACTERIZED
PROTEIN)		 1fp2 ISOFLAVONE
O-METHYLTRANSFERASE
(Medicago
sativa) 		5 / 12 LEU A 268
VAL A 275
GLY A 282
ILE A 192
LEU A 252
 None
 0.95A 3ijdB-1fp2A:
undetectable		 3ijdB-1fp2A:
21.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3MDR_B_GJZB506_1
(CHOLESTEROL
24-HYDROXYLASE)		 1fp2 ISOFLAVONE
O-METHYLTRANSFERASE
(Medicago
sativa) 		4 / 6 PHE A  84
ILE A  41
ALA A  36
ALA A 112
 None
 1.00A 3mdrB-1fp2A:
0.0		 3mdrB-1fp2A:
21.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3OU7_C_SAMC300_1
(SAM-DEPENDENT
METHYLTRANSFERASE)		 1fp2 ISOFLAVONE
O-METHYLTRANSFERASE
(Medicago
sativa) 		3 / 3 GLY A 198
ASP A 219
ASP A 239
 SAH  A1699 ( 3.9A)
SAH  A1699 (-2.9A)
SAH  A1699 (-3.8A)
 0.45A 3ou7C-1fp2A:
15.2		 3ou7C-1fp2A:
18.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3SI7_B_ACTB4_0
(CYSTIC FIBROSIS
TRANSMEMBRANE
CONDUCTANCE
REGULATOR)		 1fp2 ISOFLAVONE
O-METHYLTRANSFERASE
(Medicago
sativa) 		3 / 3 GLY A 198
GLY A 200
THR A 202
 SAH  A1699 ( 3.9A)
None
None
 0.29A 3si7B-1fp2A:
undetectable		 3si7B-1fp2A:
19.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KIC_B_SAMB401_0
(METHYLTRANSFERASE
MPPJ)		 1fp2 ISOFLAVONE
O-METHYLTRANSFERASE
(Medicago
sativa) 		5 / 12 ILE A 206
CYH A 215
GLY A 197
GLY A 200
PHE A 218
 None
None
SAH  A1699 ( 4.2A)
None
None
 1.11A 4kicB-1fp2A:
15.5		 4kicB-1fp2A:
24.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4L4C_B_CAMB502_0
(CAMPHOR
5-MONOOXYGENASE)		 1fp2 ISOFLAVONE
O-METHYLTRANSFERASE
(Medicago
sativa) 		4 / 8 PHE A 186
THR A 285
LEU A 347
ILE A 206
 None
 0.99A 4l4cB-1fp2A:
0.0		 4l4cB-1fp2A:
19.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4OKW_A_198A1001_2
(ANDROGEN RECEPTOR)		 1fp2 ISOFLAVONE
O-METHYLTRANSFERASE
(Medicago
sativa) 		4 / 7 LEU A 314
ASN A 315
LEU A 130
ILE A 134
 None
 1.05A 4okwA-1fp2A:
0.0		 4okwA-1fp2A:
21.07
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4PGH_A_SAMA401_0
(CAFFEIC ACID
O-METHYLTRANSFERASE)		 1fp2 ISOFLAVONE
O-METHYLTRANSFERASE
(Medicago
sativa) 		9 / 11 GLY A 196
GLY A 197
THR A 202
ASP A 219
VAL A 223
ASP A 239
MET A 240
LYS A 253
ILE A 255
 SAH  A1699 (-3.8A)
SAH  A1699 ( 4.2A)
None
SAH  A1699 (-2.9A)
None
SAH  A1699 (-3.8A)
SAH  A1699 (-4.0A)
SAH  A1699 (-2.7A)
SAH  A1699 (-4.9A)
 0.46A 4pghA-1fp2A:
28.2		 4pghA-1fp2A:
30.16
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4PGH_A_SAMA401_0
(CAFFEIC ACID
O-METHYLTRANSFERASE)		 1fp2 ISOFLAVONE
O-METHYLTRANSFERASE
(Medicago
sativa) 		8 / 11 GLY A 196
GLY A 197
THR A 202
VAL A 224
ASP A 239
MET A 240
LYS A 253
ILE A 255
 SAH  A1699 (-3.8A)
SAH  A1699 ( 4.2A)
None
None
SAH  A1699 (-3.8A)
SAH  A1699 (-4.0A)
SAH  A1699 (-2.7A)
SAH  A1699 (-4.9A)
 1.04A 4pghA-1fp2A:
28.2		 4pghA-1fp2A:
30.16
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4PGH_B_SAMB401_0
(CAFFEIC ACID
O-METHYLTRANSFERASE)		 1fp2 ISOFLAVONE
O-METHYLTRANSFERASE
(Medicago
sativa) 		9 / 12 ASP A 194
GLY A 196
THR A 202
ASP A 219
ASP A 239
MET A 240
LYS A 253
ILE A 255
TRP A 259
 SAH  A1699 ( 4.6A)
SAH  A1699 (-3.8A)
None
SAH  A1699 (-2.9A)
SAH  A1699 (-3.8A)
SAH  A1699 (-4.0A)
SAH  A1699 (-2.7A)
SAH  A1699 (-4.9A)
None
 0.57A 4pghB-1fp2A:
35.0		 4pghB-1fp2A:
30.16
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4PGH_C_SAMC401_0
(CAFFEIC ACID
O-METHYLTRANSFERASE)		 1fp2 ISOFLAVONE
O-METHYLTRANSFERASE
(Medicago
sativa) 		8 / 11 GLY A 196
ASP A 219
VAL A 223
ASP A 239
MET A 240
LYS A 253
ILE A 255
TRP A 259
 SAH  A1699 (-3.8A)
SAH  A1699 (-2.9A)
None
SAH  A1699 (-3.8A)
SAH  A1699 (-4.0A)
SAH  A1699 (-2.7A)
SAH  A1699 (-4.9A)
None
 0.35A 4pghC-1fp2A:
34.2		 4pghC-1fp2A:
30.16
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4PGH_C_SAMC401_0
(CAFFEIC ACID
O-METHYLTRANSFERASE)		 1fp2 ISOFLAVONE
O-METHYLTRANSFERASE
(Medicago
sativa) 		6 / 11 GLY A 196
VAL A 224
ASP A 239
MET A 240
LYS A 253
ILE A 255
 SAH  A1699 (-3.8A)
None
SAH  A1699 (-3.8A)
SAH  A1699 (-4.0A)
SAH  A1699 (-2.7A)
SAH  A1699 (-4.9A)
 1.07A 4pghC-1fp2A:
34.2		 4pghC-1fp2A:
30.16
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4PGH_D_SAMD401_0
(CAFFEIC ACID
O-METHYLTRANSFERASE)		 1fp2 ISOFLAVONE
O-METHYLTRANSFERASE
(Medicago
sativa) 		8 / 12 GLY A 196
GLY A 197
THR A 202
ASP A 219
ASP A 239
PHE A 241
LYS A 253
ILE A 255
 SAH  A1699 (-3.8A)
SAH  A1699 ( 4.2A)
None
SAH  A1699 (-2.9A)
SAH  A1699 (-3.8A)
SAH  A1699 (-4.8A)
SAH  A1699 (-2.7A)
SAH  A1699 (-4.9A)
 0.89A 4pghD-1fp2A:
34.6		 4pghD-1fp2A:
30.16
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4PGH_D_SAMD401_0
(CAFFEIC ACID
O-METHYLTRANSFERASE)		 1fp2 ISOFLAVONE
O-METHYLTRANSFERASE
(Medicago
sativa) 		9 / 12 GLY A 196
GLY A 197
THR A 202
ASP A 219
MET A 240
PHE A 241
LYS A 253
ILE A 255
TRP A 259
 SAH  A1699 (-3.8A)
SAH  A1699 ( 4.2A)
None
SAH  A1699 (-2.9A)
SAH  A1699 (-4.0A)
SAH  A1699 (-4.8A)
SAH  A1699 (-2.7A)
SAH  A1699 (-4.9A)
None
 0.80A 4pghD-1fp2A:
34.6		 4pghD-1fp2A:
30.16
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4PGH_D_SAMD401_0
(CAFFEIC ACID
O-METHYLTRANSFERASE)		 1fp2 ISOFLAVONE
O-METHYLTRANSFERASE
(Medicago
sativa) 		7 / 12 GLY A 198
THR A 202
ASP A 219
ASP A 239
PHE A 241
LYS A 253
ILE A 255
 SAH  A1699 ( 3.9A)
None
SAH  A1699 (-2.9A)
SAH  A1699 (-3.8A)
SAH  A1699 (-4.8A)
SAH  A1699 (-2.7A)
SAH  A1699 (-4.9A)
 1.38A 4pghD-1fp2A:
34.6		 4pghD-1fp2A:
30.16
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4PGH_D_SAMD401_0
(CAFFEIC ACID
O-METHYLTRANSFERASE)		 1fp2 ISOFLAVONE
O-METHYLTRANSFERASE
(Medicago
sativa) 		8 / 12 GLY A 198
THR A 202
ASP A 219
MET A 240
PHE A 241
LYS A 253
ILE A 255
TRP A 259
 SAH  A1699 ( 3.9A)
None
SAH  A1699 (-2.9A)
SAH  A1699 (-4.0A)
SAH  A1699 (-4.8A)
SAH  A1699 (-2.7A)
SAH  A1699 (-4.9A)
None
 1.25A 4pghD-1fp2A:
34.6		 4pghD-1fp2A:
30.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4XE0_A_40LA1101_0
(PHOSPHATIDYLINOSITOL
4,5-BISPHOSPHATE
3-KINASE CATALYTIC
SUBUNIT DELTA
ISOFORM)		 1fp2 ISOFLAVONE
O-METHYLTRANSFERASE
(Medicago
sativa) 		5 / 12 ILE A 255
VAL A 250
THR A 202
ASN A 176
ASP A 219
 SAH  A1699 (-4.9A)
None
None
None
SAH  A1699 (-2.9A)
 1.46A 4xe0A-1fp2A:
undetectable		 4xe0A-1fp2A:
16.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5A06_D_SORD1341_0
(ALDOSE-ALDOSE
OXIDOREDUCTASE)		 1fp2 ISOFLAVONE
O-METHYLTRANSFERASE
(Medicago
sativa) 		4 / 6 CYH A 215
GLY A 196
GLY A 197
ASP A 219
 None
SAH  A1699 (-3.8A)
SAH  A1699 ( 4.2A)
SAH  A1699 (-2.9A)
 0.93A 5a06D-1fp2A:
3.5		 5a06D-1fp2A:
22.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5KC4_A_RBFA201_2
(RIBOFLAVIN
TRANSPORTER RIBU)		 1fp2 ISOFLAVONE
O-METHYLTRANSFERASE
(Medicago
sativa) 		3 / 3 LYS A 204
LEU A 179
ILE A 192
 None
 0.65A 5kc4A-1fp2A:
undetectable		 5kc4A-1fp2A:
22.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5KC4_E_RBFE201_2
(RIBOFLAVIN
TRANSPORTER RIBU)		 1fp2 ISOFLAVONE
O-METHYLTRANSFERASE
(Medicago
sativa) 		3 / 3 LYS A 173
ASP A 171
ILE A 206
 None
 0.86A 5kc4E-1fp2A:
0.3		 5kc4E-1fp2A:
22.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6GNG_A_QPSA601_1
(-)		 1fp2 ISOFLAVONE
O-METHYLTRANSFERASE
(Medicago
sativa) 		5 / 12 LEU A 345
THR A 201
GLY A 200
ASP A 194
ASP A 288
 None
None
None
SAH  A1699 ( 4.6A)
None
 1.18A 6gngA-1fp2A:
2.2		 6gngA-1fp2A:
19.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6I5Z_D_SAMD401_0
(O-METHYLTRANSFERASE
1)		 1fp2 ISOFLAVONE
O-METHYLTRANSFERASE
(Medicago
sativa) 		7 / 11 GLY A 196
GLY A 198
ASP A 219
VAL A 223
ASP A 239
MET A 240
LYS A 253
 SAH  A1699 (-3.8A)
SAH  A1699 ( 3.9A)
SAH  A1699 (-2.9A)
None
SAH  A1699 (-3.8A)
SAH  A1699 (-4.0A)
SAH  A1699 (-2.7A)
 0.44A 6i5zD-1fp2A:
27.0		 6i5zD-1fp2A:
28.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6I5Z_D_SAMD401_0
(O-METHYLTRANSFERASE
1)		 1fp2 ISOFLAVONE
O-METHYLTRANSFERASE
(Medicago
sativa) 		5 / 11 SER A 172
GLY A 198
ASP A 219
VAL A 223
ASP A 239
 None
SAH  A1699 ( 3.9A)
SAH  A1699 (-2.9A)
None
SAH  A1699 (-3.8A)
 0.86A 6i5zD-1fp2A:
27.0		 6i5zD-1fp2A:
28.78