SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '1fp3'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ETA_1_T441128_1
(TRANSTHYRETIN)		 1fp3 N-ACYL-D-GLUCOSAMINE
2-EPIMERASE
(Sus
scrofa) 		4 / 5 LEU A 335
GLU A 329
ALA A 322
LEU A 338
 None
 0.96A 1eta1-1fp3A:
undetectable		 1eta1-1fp3A:
16.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1JG3_A_ADNA500_1
(PROTEIN-L-ISOASPARTA
TE
O-METHYLTRANSFERASE)		 1fp3 N-ACYL-D-GLUCOSAMINE
2-EPIMERASE
(Sus
scrofa) 		5 / 11 GLN A  58
GLY A  36
GLY A  87
LEU A  91
ASP A 111
 None
 1.11A 1jg3A-1fp3A:
undetectable		 1jg3A-1fp3A:
22.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1JG3_B_ADNB550_1
(PROTEIN-L-ISOASPARTA
TE
O-METHYLTRANSFERASE)		 1fp3 N-ACYL-D-GLUCOSAMINE
2-EPIMERASE
(Sus
scrofa) 		5 / 11 GLN A  58
GLY A  36
GLY A  87
LEU A  91
ASP A 111
 None
 1.11A 1jg3B-1fp3A:
undetectable		 1jg3B-1fp3A:
22.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1LIN_A_TFPA154_1
(CALMODULIN)		 1fp3 N-ACYL-D-GLUCOSAMINE
2-EPIMERASE
(Sus
scrofa) 		4 / 7 LEU A  80
MET A  23
LEU A  19
GLU A 391
 None
 0.92A 1linA-1fp3A:
undetectable		 1linA-1fp3A:
17.34
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1QW6_A_H4BA901_1
(NITRIC-OXIDE
SYNTHASE, BRAIN)		 1fp3 N-ACYL-D-GLUCOSAMINE
2-EPIMERASE
(Sus
scrofa) 		3 / 3 ARG A  60
VAL A 383
TRP A 313
 None
 1.18A 1qw6A-1fp3A:
0.0		 1qw6A-1fp3A:
22.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1S3Z_B_RIOB501_0
(AMINOGLYCOSIDE
6'-N-ACETYLTRANSFERA
SE)		 1fp3 N-ACYL-D-GLUCOSAMINE
2-EPIMERASE
(Sus
scrofa) 		4 / 8 VAL A 272
ARG A 385
TRP A 254
GLU A 190
 None
 1.27A 1s3zA-1fp3A:
undetectable
1s3zB-1fp3A:
undetectable		 1s3zA-1fp3A:
18.25
1s3zB-1fp3A:
18.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1VAG_A_H4BA901_1
(NITRIC-OXIDE
SYNTHASE, BRAIN)		 1fp3 N-ACYL-D-GLUCOSAMINE
2-EPIMERASE
(Sus
scrofa) 		3 / 3 ARG A  60
VAL A 383
TRP A 313
 None
 1.24A 1vagA-1fp3A:
0.0		 1vagA-1fp3A:
22.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ZVI_A_H4BA901_1
(NITRIC-OXIDE
SYNTHASE, BRAIN)		 1fp3 N-ACYL-D-GLUCOSAMINE
2-EPIMERASE
(Sus
scrofa) 		3 / 3 ARG A  60
VAL A 383
TRP A 313
 None
 1.24A 1zviA-1fp3A:
0.0		 1zviA-1fp3A:
22.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3IV6_C_SAMC301_0
(PUTATIVE
ZN-DEPENDENT ALCOHOL
DEHYDROGENASE)		 1fp3 N-ACYL-D-GLUCOSAMINE
2-EPIMERASE
(Sus
scrofa) 		5 / 12 GLY A 253
ASP A 274
ILE A 273
ARG A 262
LEU A 257
 None
 1.16A 3iv6C-1fp3A:
undetectable		 3iv6C-1fp3A:
20.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3O7W_A_SAMA801_0
(LEUCINE CARBOXYL
METHYLTRANSFERASE 1)		 1fp3 N-ACYL-D-GLUCOSAMINE
2-EPIMERASE
(Sus
scrofa) 		5 / 12 GLY A  87
GLY A  36
LEU A 134
VAL A  62
TYR A  65
 None
 1.08A 3o7wA-1fp3A:
undetectable		 3o7wA-1fp3A:
21.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4LRH_D_FOLD301_1
(FOLATE RECEPTOR
ALPHA)		 1fp3 N-ACYL-D-GLUCOSAMINE
2-EPIMERASE
(Sus
scrofa) 		3 / 3 HIS A 382
TRP A  56
SER A 317
 None
 0.99A 4lrhD-1fp3A:
undetectable		 4lrhD-1fp3A:
18.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4OLB_A_TRPA901_0
(PROTEIN ARGONAUTE-2)		 1fp3 N-ACYL-D-GLUCOSAMINE
2-EPIMERASE
(Sus
scrofa) 		3 / 3 VAL A  62
ALA A  86
PHE A  38
 None
 0.92A 4olbA-1fp3A:
undetectable		 4olbA-1fp3A:
19.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4W5N_A_IPHA901_0
(PROTEIN ARGONAUTE-2)		 1fp3 N-ACYL-D-GLUCOSAMINE
2-EPIMERASE
(Sus
scrofa) 		3 / 3 VAL A  62
ALA A  86
PHE A  38
 None
 0.87A 4w5nA-1fp3A:
undetectable		 4w5nA-1fp3A:
19.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4XI3_B_29SB601_2
(ESTROGEN RECEPTOR)		 1fp3 N-ACYL-D-GLUCOSAMINE
2-EPIMERASE
(Sus
scrofa) 		4 / 5 LEU A 268
GLU A 329
LEU A 186
HIS A 208
 None
 1.09A 4xi3B-1fp3A:
0.4		 4xi3B-1fp3A:
21.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4XUE_A_SAMA303_0
(CATECHOL
O-METHYLTRANSFERASE)		 1fp3 N-ACYL-D-GLUCOSAMINE
2-EPIMERASE
(Sus
scrofa) 		5 / 12 ASN A 132
ILE A 121
CYH A 187
SER A 120
GLN A 118
 None
 1.23A 4xueA-1fp3A:
undetectable		 4xueA-1fp3A:
20.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5DXE_A_ESTA1000_1
(ESTROGEN RECEPTOR)		 1fp3 N-ACYL-D-GLUCOSAMINE
2-EPIMERASE
(Sus
scrofa) 		4 / 8 GLU A 190
LEU A 186
MET A 183
LEU A 215
 None
 1.21A 5dxeA-1fp3A:
0.8		 5dxeA-1fp3A:
20.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5JS1_A_IPHA902_0
(PROTEIN ARGONAUTE-2)		 1fp3 N-ACYL-D-GLUCOSAMINE
2-EPIMERASE
(Sus
scrofa) 		3 / 3 VAL A  62
ALA A  86
PHE A  38
 None
 0.92A 5js1A-1fp3A:
0.0		 5js1A-1fp3A:
19.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5KKZ_A_ASCA1004_0
(CYTOCHROME B
UBIQUINOL-CYTOCHROME
C REDUCTASE
IRON-SULFUR SUBUNIT)		 1fp3 N-ACYL-D-GLUCOSAMINE
2-EPIMERASE
(Sus
scrofa) 		4 / 6 HIS A 156
VAL A 155
TYR A 203
ARG A 202
 None
 1.48A 5kkzA-1fp3A:
0.0
5kkzG-1fp3A:
0.0		 5kkzA-1fp3A:
21.03
5kkzG-1fp3A:
20.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5UMX_B_RBFB202_1
(GLYOXALASE/BLEOMYCIN
RESISANCE
PROTEIN/DIOXYGENASE)		 1fp3 N-ACYL-D-GLUCOSAMINE
2-EPIMERASE
(Sus
scrofa) 		5 / 10 LEU A 240
ASN A 228
GLN A 296
GLY A 300
GLN A 305
 None
 1.47A 5umxA-1fp3A:
0.0
5umxB-1fp3A:
0.0		 5umxA-1fp3A:
12.30
5umxB-1fp3A:
12.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VLM_E_CVIE301_1
(REGULATORY PROTEIN
TETR)		 1fp3 N-ACYL-D-GLUCOSAMINE
2-EPIMERASE
(Sus
scrofa) 		4 / 7 GLY A 374
TYR A 294
TRP A 313
ASP A  50
 None
 0.96A 5vlmE-1fp3A:
undetectable		 5vlmE-1fp3A:
20.98
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5X80_C_SALC201_1
(UNCHARACTERIZED
HTH-TYPE
TRANSCRIPTIONAL
REGULATOR RV2887)		 1fp3 N-ACYL-D-GLUCOSAMINE
2-EPIMERASE
(Sus
scrofa) 		4 / 7 ARG A 351
ARG A  44
GLY A 356
TYR A 355
 None
 0.99A 5x80C-1fp3A:
0.8
5x80D-1fp3A:
0.8		 5x80C-1fp3A:
17.50
5x80D-1fp3A:
17.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6AG0_C_ACRC608_1
(ALPHA-AMYLASE)		 1fp3 N-ACYL-D-GLUCOSAMINE
2-EPIMERASE
(Sus
scrofa) 		3 / 3 TYR A 294
ALA A 369
LEU A 370
 None
 0.67A 6ag0C-1fp3A:
undetectable		 6ag0C-1fp3A:
11.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6CBZ_A_ESTA601_1
(ESTROGEN RECEPTOR)		 1fp3 N-ACYL-D-GLUCOSAMINE
2-EPIMERASE
(Sus
scrofa) 		4 / 8 GLU A 190
LEU A 186
MET A 183
LEU A 215
 None
 1.24A 6cbzA-1fp3A:
undetectable		 6cbzA-1fp3A:
11.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6NM4_A_SAMA402_0
(HISTONE-LYSINE
N-METHYLTRANSFERASE
PRDM9)		 1fp3 N-ACYL-D-GLUCOSAMINE
2-EPIMERASE
(Sus
scrofa) 		4 / 7 ALA A 252
GLY A 253
LEU A 257
CYH A 187
 None
 0.79A 6nm4A-1fp3A:
undetectable		 6nm4A-1fp3A:
18.02