SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '1fp9'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1E7C_A_HLTA4002_1
(SERUM ALBUMIN)		 1fp9 4-ALPHA-GLUCANOTRANS
FERASE
(Thermus
thermophilus) 		4 / 5 ARG A 296
ALA A 319
LYS A 318
GLU A 299
 None
 1.07A 1e7cA-1fp9A:
0.0		 1e7cA-1fp9A:
22.65
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1ESW_A_ACRA651_1
(AMYLOMALTASE)		 1fp9 4-ALPHA-GLUCANOTRANS
FERASE
(Thermus
thermophilus) 		7 / 12 SER A  57
TYR A  59
GLN A  60
TRP A 258
HIS A 394
ASN A 464
TRP A 473
 None
 0.76A 1eswA-1fp9A:
61.1		 1eswA-1fp9A:
99.80
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1ESW_A_ACRA651_1
(AMYLOMALTASE)		 1fp9 4-ALPHA-GLUCANOTRANS
FERASE
(Thermus
thermophilus) 		11 / 12 SER A  57
TYR A  59
GLN A 256
TRP A 258
HIS A 294
GLU A 340
HIS A 394
ASP A 395
ASN A 464
PRO A 466
TRP A 473
 None
 0.42A 1eswA-1fp9A:
61.1		 1eswA-1fp9A:
99.80
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1ESW_A_ACRA652_1
(AMYLOMALTASE)		 1fp9 4-ALPHA-GLUCANOTRANS
FERASE
(Thermus
thermophilus) 		6 / 6 TYR A  54
GLY A  55
ASP A  56
GLY A  98
TYR A 101
SER A 470
 None
 0.75A 1eswA-1fp9A:
61.1		 1eswA-1fp9A:
99.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1FIQ_C_SALC1335_1
(XANTHINE OXIDASE)		 1fp9 4-ALPHA-GLUCANOTRANS
FERASE
(Thermus
thermophilus) 		4 / 8 LEU A  11
VAL A 454
LEU A 455
ALA A 461
 None
 0.89A 1fiqC-1fp9A:
undetectable		 1fiqC-1fp9A:
20.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1KIA_C_SAMC2293_0
(GLYCINE
N-METHYLTRANSFERASE)		 1fp9 4-ALPHA-GLUCANOTRANS
FERASE
(Thermus
thermophilus) 		5 / 12 ILE A 292
VAL A 337
MET A 361
GLY A 212
LEU A   9
 None
 1.03A 1kiaC-1fp9A:
undetectable		 1kiaC-1fp9A:
21.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1MJ2_C_SAMC2199_0
(PROTEIN (METHIONINE
REPRESSOR))		 1fp9 4-ALPHA-GLUCANOTRANS
FERASE
(Thermus
thermophilus) 		5 / 12 ALA A 111
PHE A 115
GLY A 114
LEU A  77
PRO A  76
 None
 1.28A 1mj2C-1fp9A:
undetectable
1mj2D-1fp9A:
undetectable		 1mj2C-1fp9A:
11.18
1mj2D-1fp9A:
11.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1OS6_A_DXCA75_0
(PPCA)		 1fp9 4-ALPHA-GLUCANOTRANS
FERASE
(Thermus
thermophilus) 		4 / 8 ILE A 304
LEU A 262
PHE A 217
GLY A 297
 None
 0.79A 1os6A-1fp9A:
undetectable		 1os6A-1fp9A:
9.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1S3Z_B_RIOB501_0
(AMINOGLYCOSIDE
6'-N-ACETYLTRANSFERA
SE)		 1fp9 4-ALPHA-GLUCANOTRANS
FERASE
(Thermus
thermophilus) 		4 / 8 GLU A  28
VAL A  24
GLU A  79
ASP A  73
 None
 1.00A 1s3zA-1fp9A:
undetectable
1s3zB-1fp9A:
undetectable		 1s3zA-1fp9A:
15.14
1s3zB-1fp9A:
15.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2DXR_A_SORA1002_0
(LACTOTRANSFERRIN)		 1fp9 4-ALPHA-GLUCANOTRANS
FERASE
(Thermus
thermophilus) 		3 / 3 THR A 188
PRO A  51
TYR A 141
 None
 0.95A 2dxrA-1fp9A:
0.0		 2dxrA-1fp9A:
20.90
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2OWC_A_ACRA600_1
(4-ALPHA-GLUCANOTRANS
FERASE)		 1fp9 4-ALPHA-GLUCANOTRANS
FERASE
(Thermus
thermophilus) 		7 / 11 SER A  57
TYR A  59
GLN A  60
GLN A 256
TRP A 258
ASP A 293
TRP A 473
 None
 0.98A 2owcA-1fp9A:
59.3		 2owcA-1fp9A:
100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2OWC_A_ACRA600_1
(4-ALPHA-GLUCANOTRANS
FERASE)		 1fp9 4-ALPHA-GLUCANOTRANS
FERASE
(Thermus
thermophilus) 		10 / 11 SER A  57
TYR A  59
GLN A 256
TRP A 258
ASP A 293
HIS A 394
ASP A 395
ASN A 464
PRO A 466
TRP A 473
 None
 0.71A 2owcA-1fp9A:
59.3		 2owcA-1fp9A:
100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2OWW_A_ACRA600_1
(4-ALPHA-GLUCANOTRANS
FERASE)		 1fp9 4-ALPHA-GLUCANOTRANS
FERASE
(Thermus
thermophilus) 		8 / 11 SER A  57
TYR A  59
ASP A 293
HIS A 394
ASP A 395
ASN A 464
PRO A 466
TRP A 473
 None
 0.36A 2owwA-1fp9A:
59.0		 2owwA-1fp9A:
100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2OWW_A_ACRA600_1
(4-ALPHA-GLUCANOTRANS
FERASE)		 1fp9 4-ALPHA-GLUCANOTRANS
FERASE
(Thermus
thermophilus) 		5 / 11 SER A  57
TYR A  59
GLN A  60
ASP A 293
TRP A 473
 None
 0.63A 2owwA-1fp9A:
59.0		 2owwA-1fp9A:
100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2OWW_A_ACRA600_1
(4-ALPHA-GLUCANOTRANS
FERASE)		 1fp9 4-ALPHA-GLUCANOTRANS
FERASE
(Thermus
thermophilus) 		6 / 11 TYR A  59
TRP A 258
ASP A 293
HIS A 394
ASP A 395
PRO A 466
 None
 0.76A 2owwA-1fp9A:
59.0		 2owwA-1fp9A:
100.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2XN5_A_FUNA1356_2
(THYROXINE-BINDING
GLOBULIN)		 1fp9 4-ALPHA-GLUCANOTRANS
FERASE
(Thermus
thermophilus) 		3 / 3 LEU A 206
ARG A  30
ILE A 208
 None
 0.62A 2xn5B-1fp9A:
0.0		 2xn5B-1fp9A:
6.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ABL_C_CHDC271_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE 7A1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 1fp9 4-ALPHA-GLUCANOTRANS
FERASE
(Thermus
thermophilus) 		4 / 5 GLN A 329
PHE A 332
LEU A 324
PHE A 298
 None
 1.42A 3ablC-1fp9A:
undetectable
3ablJ-1fp9A:
0.0		 3ablC-1fp9A:
19.39
3ablJ-1fp9A:
7.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3AI8_B_HNQB255_1
(CATHEPSIN B)		 1fp9 4-ALPHA-GLUCANOTRANS
FERASE
(Thermus
thermophilus) 		4 / 6 GLN A 256
GLY A 255
HIS A 294
TRP A 258
 None
 1.41A 3ai8B-1fp9A:
undetectable		 3ai8B-1fp9A:
17.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3GV1_A_BEZA302_0
(DISULFIDE
INTERCHANGE PROTEIN)		 1fp9 4-ALPHA-GLUCANOTRANS
FERASE
(Thermus
thermophilus) 		4 / 6 PRO A 160
HIS A 151
LEU A 147
ALA A 170
 None
 1.22A 3gv1A-1fp9A:
undetectable
3gv1C-1fp9A:
undetectable		 3gv1A-1fp9A:
12.75
3gv1C-1fp9A:
12.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3GV1_B_BEZB301_0
(DISULFIDE
INTERCHANGE PROTEIN)		 1fp9 4-ALPHA-GLUCANOTRANS
FERASE
(Thermus
thermophilus) 		4 / 6 LEU A 147
ALA A 170
PRO A 160
HIS A 151
 None
 1.28A 3gv1A-1fp9A:
0.0
3gv1B-1fp9A:
0.0		 3gv1A-1fp9A:
12.75
3gv1B-1fp9A:
12.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3HCP_B_CHDB4_0
(FERROCHELATASE,
MITOCHONDRIAL)		 1fp9 4-ALPHA-GLUCANOTRANS
FERASE
(Thermus
thermophilus) 		3 / 3 GLY A 385
PRO A 359
LEU A   3
 None
 0.63A 3hcpB-1fp9A:
0.6		 3hcpB-1fp9A:
20.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3OZW_A_KKKA413_1
(FLAVOHEMOGLOBIN)		 1fp9 4-ALPHA-GLUCANOTRANS
FERASE
(Thermus
thermophilus) 		4 / 8 GLN A 195
ALA A 198
LEU A 199
LEU A  16
 None
 0.85A 3ozwA-1fp9A:
undetectable		 3ozwA-1fp9A:
21.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3WDM_B_ADNB301_1
(4-PHOSPHOPANTOATE--B
ETA-ALANINE LIGASE)		 1fp9 4-ALPHA-GLUCANOTRANS
FERASE
(Thermus
thermophilus) 		5 / 10 ALA A  29
GLY A  23
LEU A  49
LEU A  25
ASP A  73
 None
 1.04A 3wdmB-1fp9A:
1.2		 3wdmB-1fp9A:
21.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3WDM_C_ADNC301_1
(4-PHOSPHOPANTOATE--B
ETA-ALANINE LIGASE)		 1fp9 4-ALPHA-GLUCANOTRANS
FERASE
(Thermus
thermophilus) 		5 / 9 ALA A  29
GLY A  23
LEU A  49
LEU A  25
ASP A  73
 None
 1.19A 3wdmC-1fp9A:
undetectable		 3wdmC-1fp9A:
21.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3WDM_D_ADND301_1
(4-PHOSPHOPANTOATE--B
ETA-ALANINE LIGASE)		 1fp9 4-ALPHA-GLUCANOTRANS
FERASE
(Thermus
thermophilus) 		5 / 10 ALA A  29
GLY A  23
LEU A  49
LEU A  25
ASP A  73
 None
 1.03A 3wdmD-1fp9A:
undetectable		 3wdmD-1fp9A:
21.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4HAJ_A_DXCA75_0
(PPCA)		 1fp9 4-ALPHA-GLUCANOTRANS
FERASE
(Thermus
thermophilus) 		4 / 7 ILE A 304
LEU A 262
PHE A 217
GLY A 297
 None
 0.87A 4hajA-1fp9A:
undetectable		 4hajA-1fp9A:
9.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4HB6_A_DXCA75_0
(PPCA)		 1fp9 4-ALPHA-GLUCANOTRANS
FERASE
(Thermus
thermophilus) 		4 / 8 ILE A 304
LEU A 262
PHE A 217
GLY A 297
 None
 0.83A 4hb6A-1fp9A:
undetectable		 4hb6A-1fp9A:
9.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4OR0_A_NPSA603_1
(SERUM ALBUMIN)		 1fp9 4-ALPHA-GLUCANOTRANS
FERASE
(Thermus
thermophilus) 		5 / 11 SER A  15
LEU A  10
ASP A 453
LEU A 457
LEU A  11
 None
 1.43A 4or0A-1fp9A:
0.0		 4or0A-1fp9A:
22.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4W9N_C_CCSC1548_0
(ENOYL-[ACYL-CARRIER-
PROTEIN] REDUCTASE)		 1fp9 4-ALPHA-GLUCANOTRANS
FERASE
(Thermus
thermophilus) 		3 / 3 ALA A 300
TRP A 316
VAL A 317
 None
 0.21A 4w9nC-1fp9A:
0.0		 4w9nC-1fp9A:
21.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4Z4F_A_IPHA902_0
(PROTEIN ARGONAUTE-2)		 1fp9 4-ALPHA-GLUCANOTRANS
FERASE
(Thermus
thermophilus) 		4 / 7 LEU A 438
PRO A 378
LEU A 418
TYR A 417
 None
 0.99A 4z4fA-1fp9A:
undetectable		 4z4fA-1fp9A:
19.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5CSY_B_ACRB601_1
(4-ALPHA-GLUCANOTRANS
FERASE DPE1,
CHLOROPLASTIC/AMYLOP
LASTIC)		 1fp9 4-ALPHA-GLUCANOTRANS
FERASE
(Thermus
thermophilus) 		6 / 12 ARG A 291
ASP A 293
GLY A 343
PHE A 366
HIS A 394
ASP A 395
 None
 1.06A 5csyB-1fp9A:
48.4		 5csyB-1fp9A:
38.04
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5CSY_B_ACRB601_1
(4-ALPHA-GLUCANOTRANS
FERASE DPE1,
CHLOROPLASTIC/AMYLOP
LASTIC)		 1fp9 4-ALPHA-GLUCANOTRANS
FERASE
(Thermus
thermophilus) 		5 / 12 GLN A 256
TRP A 258
ASP A 293
GLY A 343
PHE A 366
 None
 0.95A 5csyB-1fp9A:
48.4		 5csyB-1fp9A:
38.04
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5CSY_B_ACRB601_1
(4-ALPHA-GLUCANOTRANS
FERASE DPE1,
CHLOROPLASTIC/AMYLOP
LASTIC)		 1fp9 4-ALPHA-GLUCANOTRANS
FERASE
(Thermus
thermophilus) 		6 / 12 TRP A 258
ASP A 293
GLU A 340
GLY A 343
PHE A 366
HIS A 394
 None
 1.13A 5csyB-1fp9A:
48.4		 5csyB-1fp9A:
38.04
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5CSY_B_ACRB601_1
(4-ALPHA-GLUCANOTRANS
FERASE DPE1,
CHLOROPLASTIC/AMYLOP
LASTIC)		 1fp9 4-ALPHA-GLUCANOTRANS
FERASE
(Thermus
thermophilus) 		6 / 12 TRP A 258
ASP A 293
GLY A 343
PHE A 366
HIS A 394
ASP A 395
 None
 1.10A 5csyB-1fp9A:
48.4		 5csyB-1fp9A:
38.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5UXC_A_ZITA307_1
(PREDICTED
AMINOGLYCOSIDE
PHOSPHOTRANSFERASE)		 1fp9 4-ALPHA-GLUCANOTRANS
FERASE
(Thermus
thermophilus) 		4 / 5 ASP A  87
PRO A 106
GLU A 110
ARG A  84
 None
 1.43A 5uxcA-1fp9A:
0.0		 5uxcA-1fp9A:
22.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6AG0_C_ACRC608_1
(ALPHA-AMYLASE)		 1fp9 4-ALPHA-GLUCANOTRANS
FERASE
(Thermus
thermophilus) 		3 / 3 TYR A 101
ALA A 107
LEU A 108
 None
 0.61A 6ag0C-1fp9A:
15.1		 6ag0C-1fp9A:
10.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6FGD_A_ACTA821_0
(GEPHYRIN)		 1fp9 4-ALPHA-GLUCANOTRANS
FERASE
(Thermus
thermophilus) 		3 / 3 ARG A 296
PHE A 295
GLY A 297
 None
 0.82A 6fgdA-1fp9A:
0.0		 6fgdA-1fp9A:
22.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6GNG_B_QPSB601_2
(-)		 1fp9 4-ALPHA-GLUCANOTRANS
FERASE
(Thermus
thermophilus) 		5 / 12 GLU A 340
GLY A 343
LEU A 342
GLY A 357
PRO A 375
 None
 1.11A 6gngB-1fp9A:
undetectable		 6gngB-1fp9A:
22.96