SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '1fpz'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KP6_A_SALA3002_1
(TRANSCRIPTIONAL
REGULATOR TCAR)		 1fpz CYCLIN-DEPENDENT
KINASE INHIBITOR 3
(Homo
sapiens) 		5 / 8 LEU A  32
LEU A 154
ILE A 162
VAL A  37
LEU A  34
 None
 1.34A 3kp6A-1fpzA:
undetectable
3kp6B-1fpzA:
undetectable		 3kp6A-1fpzA:
21.50
3kp6B-1fpzA:
21.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ODO_B_FK5B203_2
(PEPTIDYL-PROLYL
CIS-TRANS ISOMERASE
SLYD)		 1fpz CYCLIN-DEPENDENT
KINASE INHIBITOR 3
(Homo
sapiens) 		3 / 3 ALA A 167
GLN A 185
GLY A 112
 None
 0.60A 4odoC-1fpzA:
undetectable		 4odoC-1fpzA:
19.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4XK8_A_PQNA845_1
(PHOTOSYSTEM I P700
CHLOROPHYLL A
APOPROTEIN A1)		 1fpz CYCLIN-DEPENDENT
KINASE INHIBITOR 3
(Homo
sapiens) 		4 / 8 SER A  30
ALA A 179
LEU A 144
GLY A 143
 None
None
None
SO4  A 900 ( 4.7A)
 0.85A 4xk8a-1fpzA:
undetectable		 4xk8a-1fpzA:
13.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5TE8_C_08JC602_1
(CYTOCHROME P450 3A4)		 1fpz CYCLIN-DEPENDENT
KINASE INHIBITOR 3
(Homo
sapiens) 		4 / 7 LEU A 155
ALA A 151
ILE A 180
LEU A 189
 None
 0.92A 5te8C-1fpzA:
0.0		 5te8C-1fpzA:
16.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VKQ_A_PCFA1807_0
(NO MECHANORECEPTOR
POTENTIAL C ISOFORM
L)		 1fpz CYCLIN-DEPENDENT
KINASE INHIBITOR 3
(Homo
sapiens) 		5 / 7 LEU A 126
ILE A 138
GLY A  44
LEU A  45
ILE A 180
 None
 1.14A 5vkqA-1fpzA:
0.0
5vkqB-1fpzA:
0.0		 5vkqA-1fpzA:
8.60
5vkqB-1fpzA:
8.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VKQ_B_PCFB1804_0
(NO MECHANORECEPTOR
POTENTIAL C ISOFORM
L)		 1fpz CYCLIN-DEPENDENT
KINASE INHIBITOR 3
(Homo
sapiens) 		5 / 8 LEU A 126
ILE A 138
GLY A  44
LEU A  45
ILE A 180
 None
 1.14A 5vkqB-1fpzA:
0.0
5vkqC-1fpzA:
0.0		 5vkqB-1fpzA:
8.60
5vkqC-1fpzA:
8.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5Y7P_E_CHDE401_0
(BILE SALT HYDROLASE)		 1fpz CYCLIN-DEPENDENT
KINASE INHIBITOR 3
(Homo
sapiens) 		4 / 8 LEU A 156
LEU A 154
ALA A 151
LEU A  32
 None
 0.84A 5y7pE-1fpzA:
0.0		 5y7pE-1fpzA:
20.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6DH0_A_017A101_2
(PROTEASE)		 1fpz CYCLIN-DEPENDENT
KINASE INHIBITOR 3
(Homo
sapiens) 		3 / 3 LEU A 149
ASP A 169
ILE A 162
 None
 0.52A 6dh0B-1fpzA:
0.0		 6dh0B-1fpzA:
18.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6F6S_B_CXQB705_1
(ENVELOPE
GLYCOPROTEIN,ENVELOP
E GLYCOPROTEIN,GP1
ENVELOPE
GLYCOPROTEIN)		 1fpz CYCLIN-DEPENDENT
KINASE INHIBITOR 3
(Homo
sapiens) 		4 / 6 VAL A  37
LEU A  34
LEU A  32
LEU A 126
 None
 0.91A 6f6sA-1fpzA:
0.0
6f6sB-1fpzA:
0.0		 6f6sA-1fpzA:
16.51
6f6sB-1fpzA:
18.72