SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '1fq9'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1V55_P_CHDP4271_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE III
CYTOCHROME C OXIDASE
POLYPEPTIDE
VIIA-HEART)		 1fq9 FIBROBLAST GROWTH
FACTOR 2
(Homo
sapiens) 		4 / 7 LEU A  53
GLN A  54
LEU A  32
PHE A 139
 None
 1.03A 1v55P-1fq9A:
undetectable
1v55W-1fq9A:
0.0		 1v55P-1fq9A:
19.75
1v55W-1fq9A:
22.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ZLQ_A_ACTA1507_0
(NICKEL-BINDING
PERIPLASMIC PROTEIN)		 1fq9 FIBROBLAST GROWTH
FACTOR 2
FIBROBLAST GROWTH
FACTOR RECEPTOR 1
(Homo
sapiens;
Homo
sapiens) 		3 / 3 GLN C 288
HIS C 286
ARG A  60
 None
 1.01A 1zlqA-1fq9C:
0.0		 1zlqA-1fq9C:
19.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2EIJ_P_CHDP1271_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE
VIIA-HEART
CYTOCHROME C OXIDASE
SUBUNIT 3)		 1fq9 FIBROBLAST GROWTH
FACTOR 2
(Homo
sapiens) 		4 / 7 LEU A  53
GLN A  54
LEU A  32
PHE A 139
 None
 0.96A 2eijP-1fq9A:
undetectable
2eijW-1fq9A:
0.0		 2eijP-1fq9A:
19.75
2eijW-1fq9A:
22.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2EIL_P_CHDP1271_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE
VIIA-HEART
CYTOCHROME C OXIDASE
SUBUNIT 3)		 1fq9 FIBROBLAST GROWTH
FACTOR 2
(Homo
sapiens) 		4 / 8 LEU A  53
GLN A  54
LEU A  32
PHE A 139
 None
 0.95A 2eilP-1fq9A:
undetectable
2eilW-1fq9A:
0.0		 2eilP-1fq9A:
19.75
2eilW-1fq9A:
22.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2IT4_A_PPFA500_1
(CARBONIC ANHYDRASE 1)		 1fq9 FIBROBLAST GROWTH
FACTOR RECEPTOR 1
(Homo
sapiens) 		5 / 8 HIS C 292
VAL C 308
LEU C 342
THR C 340
HIS C 351
 None
 1.28A 2it4A-1fq9C:
undetectable		 2it4A-1fq9C:
20.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3AG2_P_CHDP1271_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE 7A1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 1fq9 FIBROBLAST GROWTH
FACTOR 2
(Homo
sapiens) 		4 / 7 LEU A  53
GLN A  54
LEU A  32
PHE A 139
 None
 0.97A 3ag2P-1fq9A:
undetectable
3ag2W-1fq9A:
0.0		 3ag2P-1fq9A:
19.75
3ag2W-1fq9A:
22.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BPX_B_SALB258_1
(TRANSCRIPTIONAL
REGULATOR)		 1fq9 FIBROBLAST GROWTH
FACTOR RECEPTOR 1
(Homo
sapiens) 		5 / 11 ALA C 343
LEU C 349
ARG C 254
ILE C 347
SER C 281
 None
 1.18A 3bpxA-1fq9C:
0.0
3bpxB-1fq9C:
undetectable		 3bpxA-1fq9C:
20.69
3bpxB-1fq9C:
20.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3SUF_B_SUEB1201_2
(NS3 PROTEASE, NS4A
PROTEIN)		 1fq9 FIBROBLAST GROWTH
FACTOR 2
(Homo
sapiens) 		3 / 3 TYR A 111
LEU A 138
ARG A 107
 None
 0.63A 3sufB-1fq9A:
0.0		 3sufB-1fq9A:
23.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4AC9_C_DXCC1478_0
(MJ0495-LIKE PROTEIN)		 1fq9 FIBROBLAST GROWTH
FACTOR RECEPTOR 1
(Homo
sapiens) 		4 / 7 ASP C 335
THR C 266
SER C 332
PHE C 333
 None
 0.75A 4ac9C-1fq9C:
undetectable		 4ac9C-1fq9C:
17.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4E7C_D_ACTD504_0
(UDP-N-ACETYLGLUCOSAM
INE
1-CARBOXYVINYLTRANSF
ERASE)		 1fq9 FIBROBLAST GROWTH
FACTOR RECEPTOR 1
(Homo
sapiens) 		3 / 3 GLY C 182
SER C 181
TRP C 213
 None
 0.79A 4e7cD-1fq9C:
undetectable		 4e7cD-1fq9C:
19.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4F93_B_SANB3004_1
(U5 SMALL NUCLEAR
RIBONUCLEOPROTEIN
200 KDA HELICASE)		 1fq9 FIBROBLAST GROWTH
FACTOR RECEPTOR 1
(Homo
sapiens) 		4 / 8 TRP C 213
ASN C 234
GLY C 237
SER C 238
 None
 0.88A 4f93B-1fq9C:
4.9		 4f93B-1fq9C:
8.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4J7U_D_YTZD802_1
(SEPIAPTERIN
REDUCTASE)		 1fq9 FIBROBLAST GROWTH
FACTOR 2
(Homo
sapiens) 		4 / 8 LEU A 118
CYH A  25
PHE A 139
GLN A 134
 None
None
None
SGN  A 304 (-4.3A)
 1.06A 4j7uD-1fq9A:
undetectable		 4j7uD-1fq9A:
20.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4MME_A_29QA603_1
(TRANSPORTER)		 1fq9 FIBROBLAST GROWTH
FACTOR RECEPTOR 1
(Homo
sapiens) 		5 / 9 ASP C 335
VAL C 267
ALA C 268
GLY C 337
SER C 332
 None
 1.42A 4mmeA-1fq9C:
undetectable		 4mmeA-1fq9C:
18.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5M0O_A_EPAA502_1
(TERMINAL
OLEFIN-FORMING FATTY
ACID DECARBOXYLASE)		 1fq9 FIBROBLAST GROWTH
FACTOR 2
(Homo
sapiens) 		5 / 10 PRO A 141
LEU A  53
ILE A  34
ALA A  84
VAL A 116
 None
 1.32A 5m0oA-1fq9A:
undetectable		 5m0oA-1fq9A:
15.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5UHB_C_RFPC1201_2
(DNA-DIRECTED RNA
POLYMERASE SUBUNIT
BETA)		 1fq9 FIBROBLAST GROWTH
FACTOR 2
(Homo
sapiens) 		3 / 3 PHE A  17
ASP A  19
LEU A 140
 None
 0.73A 5uhbC-1fq9A:
undetectable		 5uhbC-1fq9A:
8.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6MXT_A_K5YA1401_1
(ENDOLYSIN, BETA-2
ADRENERGIC RECEPTOR
CHIMERA)		 1fq9 FIBROBLAST GROWTH
FACTOR 2
(Homo
sapiens) 		3 / 3 ASP A  90
SER A  87
SER A  85
 None
 0.63A 6mxtA-1fq9A:
undetectable		 6mxtA-1fq9A:
16.41