SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '1fqt'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2DYR_P_CHDP1271_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE
VIIA-HEART
CYTOCHROME C OXIDASE
SUBUNIT 3)		 1fqt RIESKE-TYPE
FERREDOXIN OF
BIPHENYL DIOXYGENASE
(Paraburkholderia
xenovorans) 		4 / 8 LYS A  87
LEU A  86
PHE A  70
LEU A  50
 None
 0.93A 2dyrP-1fqtA:
undetectable
2dyrW-1fqtA:
undetectable		 2dyrP-1fqtA:
15.48
2dyrW-1fqtA:
18.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2EIL_P_CHDP1271_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE
VIIA-HEART
CYTOCHROME C OXIDASE
SUBUNIT 3)		 1fqt RIESKE-TYPE
FERREDOXIN OF
BIPHENYL DIOXYGENASE
(Paraburkholderia
xenovorans) 		4 / 8 LYS A  87
LEU A  86
PHE A  70
LEU A  50
 None
 0.95A 2eilP-1fqtA:
undetectable
2eilW-1fqtA:
0.0		 2eilP-1fqtA:
15.48
2eilW-1fqtA:
18.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2EIM_W_CHDW1271_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE
VIIA-HEART
CYTOCHROME C OXIDASE
SUBUNIT 3)		 1fqt RIESKE-TYPE
FERREDOXIN OF
BIPHENYL DIOXYGENASE
(Paraburkholderia
xenovorans) 		4 / 7 LYS A  87
LEU A  86
PHE A  70
LEU A  50
 None
 0.94A 2eimP-1fqtA:
undetectable
2eimW-1fqtA:
undetectable		 2eimP-1fqtA:
15.48
2eimW-1fqtA:
18.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ASN_P_CHDP1271_0
(CYTOCHROME C OXIDASE
SUBUNIT 3
CYTOCHROME C OXIDASE
SUBUNIT 7A1)		 1fqt RIESKE-TYPE
FERREDOXIN OF
BIPHENYL DIOXYGENASE
(Paraburkholderia
xenovorans) 		4 / 7 LYS A  87
LEU A  86
PHE A  70
LEU A  50
 None
 0.92A 3asnP-1fqtA:
undetectable
3asnW-1fqtA:
0.0		 3asnP-1fqtA:
15.48
3asnW-1fqtA:
18.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ASO_C_CHDC271_0
(CYTOCHROME C OXIDASE
SUBUNIT 3
CYTOCHROME C OXIDASE
SUBUNIT 7A1)		 1fqt RIESKE-TYPE
FERREDOXIN OF
BIPHENYL DIOXYGENASE
(Paraburkholderia
xenovorans) 		4 / 8 LYS A  87
LEU A  86
PHE A  70
LEU A  50
 None
 0.95A 3asoC-1fqtA:
undetectable
3asoJ-1fqtA:
0.0		 3asoC-1fqtA:
15.48
3asoJ-1fqtA:
18.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ASO_P_CHDP1271_0
(CYTOCHROME C OXIDASE
SUBUNIT 3
CYTOCHROME C OXIDASE
SUBUNIT 7A1)		 1fqt RIESKE-TYPE
FERREDOXIN OF
BIPHENYL DIOXYGENASE
(Paraburkholderia
xenovorans) 		4 / 7 LYS A  87
LEU A  86
PHE A  70
LEU A  50
 None
 0.96A 3asoP-1fqtA:
undetectable
3asoW-1fqtA:
undetectable		 3asoP-1fqtA:
15.48
3asoW-1fqtA:
18.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3W9T_E_W9TE506_1
(HEMOLYTIC LECTIN
CEL-III)		 1fqt RIESKE-TYPE
FERREDOXIN OF
BIPHENYL DIOXYGENASE
(Paraburkholderia
xenovorans) 		4 / 6 CYH A  43
THR A  44
CYH A  63
GLY A  68
 FES  A1001 (-2.2A)
None
FES  A1001 (-2.3A)
FES  A1001 (-3.9A)
 1.39A 3w9tE-1fqtA:
0.0		 3w9tE-1fqtA:
13.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4Z2E_H_TR6H101_1
(DNA GYRASE SUBUNIT A
DNA GYRASE SUBUNIT B
SYMMETRIZED E-SITE
DNA)		 1fqt RIESKE-TYPE
FERREDOXIN OF
BIPHENYL DIOXYGENASE
(Paraburkholderia
xenovorans) 		3 / 5 GLY A  15
GLY A  58
GLU A  57
 None
 0.45A 4z2eA-1fqtA:
undetectable
4z2eD-1fqtA:
undetectable		 4z2eA-1fqtA:
13.54
4z2eD-1fqtA:
18.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5B3S_P_CHDP306_0
(CYTOCHROME C OXIDASE
SUBUNIT 3)		 1fqt RIESKE-TYPE
FERREDOXIN OF
BIPHENYL DIOXYGENASE
(Paraburkholderia
xenovorans) 		4 / 7 LYS A  87
LEU A  86
PHE A  70
LEU A  50
 None
 0.94A 5b3sP-1fqtA:
undetectable		 5b3sP-1fqtA:
15.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5UXC_A_ZITA307_1
(PREDICTED
AMINOGLYCOSIDE
PHOSPHOTRANSFERASE)		 1fqt RIESKE-TYPE
FERREDOXIN OF
BIPHENYL DIOXYGENASE
(Paraburkholderia
xenovorans) 		4 / 5 ASP A  47
PRO A  82
GLU A  84
THR A  44
 None
FES  A1001 ( 4.4A)
GOL  A 901 (-4.0A)
None
 1.48A 5uxcA-1fqtA:
0.0		 5uxcA-1fqtA:
17.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VLM_G_CVIG301_0
(REGULATORY PROTEIN
TETR)		 1fqt RIESKE-TYPE
FERREDOXIN OF
BIPHENYL DIOXYGENASE
(Paraburkholderia
xenovorans) 		5 / 12 ALA A  17
LEU A  36
ILE A  91
VAL A  20
ASP A  97
 None
GOL  A 902 (-4.1A)
GOL  A 902 (-4.3A)
None
None
 1.30A 5vlmG-1fqtA:
undetectable		 5vlmG-1fqtA:
19.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5X19_P_CHDP305_0
(CYTOCHROME C OXIDASE
SUBUNIT 3)		 1fqt RIESKE-TYPE
FERREDOXIN OF
BIPHENYL DIOXYGENASE
(Paraburkholderia
xenovorans) 		4 / 6 LYS A  87
LEU A  86
PHE A  70
LEU A  50
 None
 0.97A 5x19P-1fqtA:
undetectable		 5x19P-1fqtA:
15.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5X1F_P_CHDP304_0
(CYTOCHROME C OXIDASE
SUBUNIT 3
CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)		 1fqt RIESKE-TYPE
FERREDOXIN OF
BIPHENYL DIOXYGENASE
(Paraburkholderia
xenovorans) 		4 / 7 LYS A  87
LEU A  86
PHE A  70
LEU A  50
 None
 0.95A 5x1fP-1fqtA:
undetectable
5x1fW-1fqtA:
undetectable		 5x1fP-1fqtA:
15.48
5x1fW-1fqtA:
18.69