SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '1frr'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4YB6_A_HISA302_0
(ATP
PHOSPHORIBOSYLTRANSF
ERASE)		 1frr FERREDOXIN I
(Equisetum
arvense) 		5 / 10 GLY A  48
VAL A  73
VAL A  50
LEU A  34
LEU A  84
 None
 1.20A 4yb6A-1frrA:
undetectable
4yb6E-1frrA:
undetectable		 4yb6A-1frrA:
15.33
4yb6E-1frrA:
15.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4YB6_C_HISC302_0
(ATP
PHOSPHORIBOSYLTRANSF
ERASE)		 1frr FERREDOXIN I
(Equisetum
arvense) 		5 / 10 GLY A  48
VAL A  73
VAL A  50
LEU A  34
LEU A  84
 None
 1.19A 4yb6C-1frrA:
undetectable
4yb6F-1frrA:
undetectable		 4yb6C-1frrA:
15.33
4yb6F-1frrA:
15.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4YB6_C_HISC302_0
(ATP
PHOSPHORIBOSYLTRANSF
ERASE)		 1frr FERREDOXIN I
(Equisetum
arvense) 		5 / 10 VAL A  73
THR A  88
VAL A  50
LEU A  34
LEU A  84
 None
 1.32A 4yb6C-1frrA:
undetectable
4yb6F-1frrA:
undetectable		 4yb6C-1frrA:
15.33
4yb6F-1frrA:
15.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4YB6_D_HISD302_0
(ATP
PHOSPHORIBOSYLTRANSF
ERASE)		 1frr FERREDOXIN I
(Equisetum
arvense) 		5 / 10 LEU A  34
LEU A  84
GLY A  48
VAL A  73
VAL A  50
 None
 1.20A 4yb6A-1frrA:
undetectable
4yb6D-1frrA:
undetectable		 4yb6A-1frrA:
15.33
4yb6D-1frrA:
15.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4YB6_E_HISE302_0
(ATP
PHOSPHORIBOSYLTRANSF
ERASE)		 1frr FERREDOXIN I
(Equisetum
arvense) 		5 / 10 LEU A  34
LEU A  84
VAL A  73
THR A  88
VAL A  50
 None
 1.33A 4yb6D-1frrA:
undetectable
4yb6E-1frrA:
undetectable		 4yb6D-1frrA:
15.33
4yb6E-1frrA:
15.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4YB6_F_HISF302_0
(ATP
PHOSPHORIBOSYLTRANSF
ERASE)		 1frr FERREDOXIN I
(Equisetum
arvense) 		5 / 10 LEU A  34
LEU A  84
GLY A  48
VAL A  73
VAL A  50
 None
 1.21A 4yb6B-1frrA:
undetectable
4yb6F-1frrA:
undetectable		 4yb6B-1frrA:
15.33
4yb6F-1frrA:
15.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6A4I_B_TRPB403_0
(TRYPTOPHAN
2,3-DIOXYGENASE)		 1frr FERREDOXIN I
(Equisetum
arvense) 		4 / 7 GLU A  92
THR A   8
PRO A   9
PRO A  35
 None
 1.10A 6a4iB-1frrA:
undetectable		 6a4iB-1frrA:
17.09