SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '1fs0'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1EE2_A_CHDA1150_0
(ALCOHOL
DEHYDROGENASE)		 1fs0 ATP SYNTHASE GAMMA
SUBUNIT
(Escherichia
coli) 		5 / 11 LEU G 189
HIS G  65
LEU G  68
VAL G 224
ILE G  53
 None
 1.16A 1ee2A-1fs0G:
3.3		 1ee2A-1fs0G:
22.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1EE2_B_CHDB1250_1
(ALCOHOL
DEHYDROGENASE)		 1fs0 ATP SYNTHASE GAMMA
SUBUNIT
(Escherichia
coli) 		5 / 11 LEU G 189
HIS G  65
LEU G  68
VAL G 224
ILE G  53
 None
 1.16A 1ee2B-1fs0G:
undetectable		 1ee2B-1fs0G:
22.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2YY8_B_SAMB500_0
(UPF0106 PROTEIN
PH0461)		 1fs0 ATP SYNTHASE GAMMA
SUBUNIT
(Escherichia
coli) 		5 / 11 LEU G 236
VAL G 233
GLY G 231
GLU G 234
ALA G 237
 None
 1.11A 2yy8A-1fs0G:
2.4
2yy8B-1fs0G:
undetectable		 2yy8A-1fs0G:
21.60
2yy8B-1fs0G:
21.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3UQ6_B_ADNB401_2
(ADENOSINE KINASE,
PUTATIVE)		 1fs0 ATP SYNTHASE GAMMA
SUBUNIT
(Escherichia
coli) 		4 / 5 LEU G 115
GLY G 131
PHE G  96
ASN G 127
 None
 1.24A 3uq6B-1fs0G:
undetectable		 3uq6B-1fs0G:
18.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4D1Y_A_RBFA1176_1
(PUTATIVE PROTEASE I)		 1fs0 ATP SYNTHASE GAMMA
SUBUNIT
(Escherichia
coli) 		4 / 8 ASN G 235
GLN G 181
ASN G 177
THR G 178
 None
 1.28A 4d1yA-1fs0G:
2.4
4d1yB-1fs0G:
2.5		 4d1yA-1fs0G:
19.31
4d1yB-1fs0G:
19.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5KC4_A_RBFA201_1
(RIBOFLAVIN
TRANSPORTER RIBU)		 1fs0 ATP SYNTHASE GAMMA
SUBUNIT
(Escherichia
coli) 		5 / 12 GLU G 148
LEU G 149
ASP G  84
GLY G 119
ALA G 116
 None
 1.46A 5kc4A-1fs0G:
0.0		 5kc4A-1fs0G:
22.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6EKZ_A_SNPA414_0
(AROMATIC
PEROXYGENASE)		 1fs0 ATP SYNTHASE GAMMA
SUBUNIT
(Escherichia
coli) 		4 / 5 VAL G 123
PRO G 152
MET G 156
VAL G 228
 None
 1.37A 6ekzA-1fs0G:
0.0		 6ekzA-1fs0G:
15.62