SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '1fsl'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1LH6_A_NIOA155_1
(LEGHEMOGLOBIN A
(NICOTINATE MET))		 1fsl LEGHEMOGLOBIN A
(Glycine
max) 		5 / 7 PHE A  29
PHE A  44
PHE A  46
HIS A  61
HIS A  92
 NIO  A 145 ( 4.9A)
HEM  A 144 ( 3.8A)
NIO  A 145 (-4.8A)
HEM  A 144 ( 3.6A)
HEM  A 144 (-3.4A)
 0.89A 1lh6A-1fslA:
19.4		 1lh6A-1fslA:
55.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3OZU_A_X89A411_1
(FLAVOHEMOPROTEIN)		 1fsl LEGHEMOGLOBIN A
(Glycine
max) 		5 / 12 PHE A  29
TYR A  30
HIS A  92
ALA A 132
TYR A 133
 NIO  A 145 ( 4.9A)
NIO  A 145 (-4.6A)
HEM  A 144 (-3.4A)
None
HEM  A 144 (-2.9A)
 0.80A 3ozuA-1fslA:
12.2		 3ozuA-1fslA:
17.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4G1B_A_ECNA403_1
(FLAVOHEMOGLOBIN)		 1fsl LEGHEMOGLOBIN A
(Glycine
max) 		5 / 12 PHE A  29
TYR A  30
VAL A 105
LEU A 109
TYR A 133
 NIO  A 145 ( 4.9A)
NIO  A 145 (-4.6A)
NIO  A 145 ( 4.0A)
None
HEM  A 144 (-2.9A)
 0.67A 4g1bA-1fslA:
13.5		 4g1bA-1fslA:
18.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4G1B_A_ECNA403_1
(FLAVOHEMOGLOBIN)		 1fsl LEGHEMOGLOBIN A
(Glycine
max) 		5 / 12 TYR A  30
PHE A  44
VAL A 105
LEU A 109
TYR A 133
 NIO  A 145 (-4.6A)
HEM  A 144 ( 3.8A)
NIO  A 145 ( 4.0A)
None
HEM  A 144 (-2.9A)
 0.78A 4g1bA-1fslA:
13.5		 4g1bA-1fslA:
18.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5YW0_A_ACTA410_0
(UNCHARACTERIZED
PROTEIN KDOO)		 1fsl LEGHEMOGLOBIN A
(Glycine
max) 		4 / 4 GLY A  80
LEU A  76
VAL A   1
GLU A 135
 None
 1.48A 5yw0A-1fslA:
undetectable		 5yw0A-1fslA:
20.82