SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '1fsu'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1KIA_C_SAMC2293_0
(GLYCINE
N-METHYLTRANSFERASE)		 1fsu N-ACETYLGALACTOSAMIN
E-4-SULFATASE
(Homo
sapiens) 		5 / 12 GLY A 144
ASP A  53
MET A 142
GLY A 171
LEU A 194
 None
CA  A 604 ( 3.4A)
None
ALS  A  91 ( 4.4A)
None
 1.14A 1kiaC-1fsuA:
undetectable		 1kiaC-1fsuA:
21.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1NX9_A_AICA5001_1
(ALPHA-AMINO ACID
ESTER HYDROLASE)		 1fsu N-ACETYLGALACTOSAMIN
E-4-SULFATASE
(Homo
sapiens) 		4 / 8 TYR A 251
TYR A 255
GLU A 250
TYR A 176
 None
 1.28A 1nx9A-1fsuA:
undetectable		 1nx9A-1fsuA:
20.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1NX9_B_AICB5002_1
(ALPHA-AMINO ACID
ESTER HYDROLASE)		 1fsu N-ACETYLGALACTOSAMIN
E-4-SULFATASE
(Homo
sapiens) 		4 / 8 TYR A 251
TYR A 255
GLU A 250
TYR A 176
 None
 1.27A 1nx9B-1fsuA:
undetectable		 1nx9B-1fsuA:
20.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1NX9_C_AICC5003_1
(ALPHA-AMINO ACID
ESTER HYDROLASE)		 1fsu N-ACETYLGALACTOSAMIN
E-4-SULFATASE
(Homo
sapiens) 		4 / 8 TYR A 251
TYR A 255
GLU A 250
TYR A 176
 None
 1.27A 1nx9C-1fsuA:
undetectable		 1nx9C-1fsuA:
20.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1NX9_D_AICD5004_1
(ALPHA-AMINO ACID
ESTER HYDROLASE)		 1fsu N-ACETYLGALACTOSAMIN
E-4-SULFATASE
(Homo
sapiens) 		4 / 8 TYR A 251
TYR A 255
GLU A 250
TYR A 176
 None
 1.26A 1nx9D-1fsuA:
undetectable		 1nx9D-1fsuA:
20.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1T86_A_CAMA1422_0
(CYTOCHROME P450-CAM)		 1fsu N-ACETYLGALACTOSAMIN
E-4-SULFATASE
(Homo
sapiens) 		4 / 8 PHE A 297
THR A  69
THR A 299
VAL A 241
 None
 0.94A 1t86A-1fsuA:
undetectable		 1t86A-1fsuA:
21.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1YA3_B_STRB2001_2
(MINERALOCORTICOID
RECEPTOR)		 1fsu N-ACETYLGALACTOSAMIN
E-4-SULFATASE
(Homo
sapiens) 		3 / 3 LEU A 148
LEU A 156
MET A 142
 None
 0.78A 1ya3B-1fsuA:
0.0		 1ya3B-1fsuA:
19.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2AVS_B_MK1B902_1
(POL POLYPROTEIN)		 1fsu N-ACETYLGALACTOSAMIN
E-4-SULFATASE
(Homo
sapiens) 		5 / 12 GLY A 268
ALA A 267
GLY A 309
GLY A 308
ILE A 258
 None
 0.68A 2avsA-1fsuA:
undetectable		 2avsA-1fsuA:
13.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2AVV_A_MK1A901_1
(POL POLYPROTEIN)		 1fsu N-ACETYLGALACTOSAMIN
E-4-SULFATASE
(Homo
sapiens) 		5 / 12 GLY A 268
ALA A 267
GLY A 309
GLY A 308
ILE A 258
 None
 0.77A 2avvA-1fsuA:
undetectable		 2avvA-1fsuA:
13.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2BXQ_A_IMNA2001_1
(SERUM ALBUMIN)		 1fsu N-ACETYLGALACTOSAMIN
E-4-SULFATASE
(Homo
sapiens) 		5 / 10 ALA A 276
ALA A 219
ARG A 218
LEU A 222
LEU A 234
 NAG  A 600 (-3.6A)
None
None
None
None
 1.09A 2bxqA-1fsuA:
undetectable		 2bxqA-1fsuA:
22.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2FXE_A_DR7A102_1
(POL PROTEIN)		 1fsu N-ACETYLGALACTOSAMIN
E-4-SULFATASE
(Homo
sapiens) 		5 / 12 GLY A 268
ALA A 267
GLY A 309
GLY A 308
ILE A 258
 None
 0.77A 2fxeA-1fsuA:
0.0		 2fxeA-1fsuA:
13.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2HRC_A_CHDA703_0
(FERROCHELATASE)		 1fsu N-ACETYLGALACTOSAMIN
E-4-SULFATASE
(Homo
sapiens) 		4 / 4 LEU A 129
PRO A 130
LEU A  99
ARG A  95
 None
None
None
ALS  A  91 (-4.6A)
 1.39A 2hrcA-1fsuA:
0.0		 2hrcA-1fsuA:
20.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2Q64_B_1UNB1001_2
(PROTEASE RETROPEPSIN)		 1fsu N-ACETYLGALACTOSAMIN
E-4-SULFATASE
(Homo
sapiens) 		3 / 3 ARG A 160
THR A 107
VAL A 122
 None
 0.89A 2q64A-1fsuA:
0.0		 2q64A-1fsuA:
13.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2QAK_A_1UNA1001_2
(PROTEASE RETROPEPSIN)		 1fsu N-ACETYLGALACTOSAMIN
E-4-SULFATASE
(Homo
sapiens) 		3 / 3 ARG A 160
THR A 107
VAL A 122
 None
 0.89A 2qakA-1fsuA:
0.0		 2qakA-1fsuA:
13.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2XRL_A_DXTA1211_1
(TETRACYCLINE
REPRESSOR PROTEIN
CLASS D)		 1fsu N-ACETYLGALACTOSAMIN
E-4-SULFATASE
(Homo
sapiens) 		5 / 12 SER A 428
ASN A 426
THR A 471
LEU A 440
SER A 423
 NAG  A 602 ( 4.7A)
NAG  A 602 (-2.0A)
None
None
None
 1.35A 2xrlA-1fsuA:
undetectable		 2xrlA-1fsuA:
18.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BGD_A_PM6A302_1
(THIOPURINE
S-METHYLTRANSFERASE)		 1fsu N-ACETYLGALACTOSAMIN
E-4-SULFATASE
(Homo
sapiens) 		4 / 6 THR A 164
PHE A 162
LEU A 232
LEU A 234
 None
 1.03A 3bgdA-1fsuA:
0.0		 3bgdA-1fsuA:
17.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3CYX_A_ROCA201_3
(HIV-1 PROTEASE)		 1fsu N-ACETYLGALACTOSAMIN
E-4-SULFATASE
(Homo
sapiens) 		5 / 12 GLY A 268
ALA A 267
GLY A 309
GLY A 308
ILE A 258
 None
 0.73A 3cyxB-1fsuA:
undetectable		 3cyxB-1fsuA:
13.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3D2T_A_1FLA502_1
(TRANSTHYRETIN)		 1fsu N-ACETYLGALACTOSAMIN
E-4-SULFATASE
(Homo
sapiens) 		4 / 7 LEU A 392
ALA A 431
THR A 442
VAL A 429
 None
None
None
NAG  A 602 (-4.2A)
 0.87A 3d2tA-1fsuA:
0.0		 3d2tA-1fsuA:
13.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3DCJ_A_THHA401_0
(PROBABLE
5'-PHOSPHORIBOSYLGLY
CINAMIDE
FORMYLTRANSFERASE
PURN)		 1fsu N-ACETYLGALACTOSAMIN
E-4-SULFATASE
(Homo
sapiens) 		5 / 12 ILE A 220
LEU A 222
LEU A 234
VAL A 143
THR A 216
 None
None
None
None
NAG  A 600 ( 4.0A)
 1.12A 3dcjA-1fsuA:
undetectable
3dcjB-1fsuA:
undetectable		 3dcjA-1fsuA:
17.24
3dcjB-1fsuA:
17.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3DLC_A_SAMA220_0
(PUTATIVE
S-ADENOSYL-L-METHION
INE-DEPENDENT
METHYLTRANSFERASE)		 1fsu N-ACETYLGALACTOSAMIN
E-4-SULFATASE
(Homo
sapiens) 		5 / 12 GLY A 302
GLY A 328
SER A 298
ASP A  53
HIS A 242
 None
None
None
CA  A 604 ( 3.4A)
ALS  A  91 (-3.7A)
 1.26A 3dlcA-1fsuA:
undetectable		 3dlcA-1fsuA:
17.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3FHJ_A_TRPA1001_0
(TRYPTOPHANYL-TRNA
SYNTHETASE)		 1fsu N-ACETYLGALACTOSAMIN
E-4-SULFATASE
(Homo
sapiens) 		5 / 10 GLY A 308
GLN A 304
ILE A  67
VAL A 270
VAL A 241
 None
 1.33A 3fhjA-1fsuA:
undetectable		 3fhjA-1fsuA:
19.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3FHJ_B_TRPB1001_0
(TRYPTOPHANYL-TRNA
SYNTHETASE)		 1fsu N-ACETYLGALACTOSAMIN
E-4-SULFATASE
(Homo
sapiens) 		5 / 10 GLY A 308
GLN A 304
ILE A  67
VAL A 270
VAL A 241
 None
 1.35A 3fhjB-1fsuA:
undetectable		 3fhjB-1fsuA:
19.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3FHJ_C_TRPC1001_0
(TRYPTOPHANYL-TRNA
SYNTHETASE)		 1fsu N-ACETYLGALACTOSAMIN
E-4-SULFATASE
(Homo
sapiens) 		5 / 10 GLY A 308
GLN A 304
ILE A  67
VAL A 270
VAL A 241
 None
 1.32A 3fhjC-1fsuA:
undetectable		 3fhjC-1fsuA:
19.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3FHJ_E_TRPE1001_0
(TRYPTOPHANYL-TRNA
SYNTHETASE)		 1fsu N-ACETYLGALACTOSAMIN
E-4-SULFATASE
(Homo
sapiens) 		5 / 10 GLY A 308
GLN A 304
ILE A  67
VAL A 270
VAL A 241
 None
 1.25A 3fhjE-1fsuA:
undetectable		 3fhjE-1fsuA:
19.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3FI0_A_TRPA1001_0
(TRYPTOPHANYL-TRNA
SYNTHETASE)		 1fsu N-ACETYLGALACTOSAMIN
E-4-SULFATASE
(Homo
sapiens) 		5 / 9 GLY A 308
GLN A 304
ILE A  67
VAL A 270
VAL A 241
 None
 1.32A 3fi0A-1fsuA:
undetectable		 3fi0A-1fsuA:
19.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3FI0_C_TRPC1001_0
(TRYPTOPHANYL-TRNA
SYNTHETASE)		 1fsu N-ACETYLGALACTOSAMIN
E-4-SULFATASE
(Homo
sapiens) 		5 / 9 GLY A 308
GLN A 304
ILE A  67
VAL A 270
VAL A 241
 None
 1.32A 3fi0C-1fsuA:
undetectable		 3fi0C-1fsuA:
19.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3FI0_H_TRPH1001_0
(TRYPTOPHANYL-TRNA
SYNTHETASE)		 1fsu N-ACETYLGALACTOSAMIN
E-4-SULFATASE
(Homo
sapiens) 		5 / 9 GLY A 308
GLN A 304
ILE A  67
VAL A 270
VAL A 241
 None
 1.32A 3fi0H-1fsuA:
undetectable		 3fi0H-1fsuA:
19.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3FI0_K_TRPK1001_0
(TRYPTOPHANYL-TRNA
SYNTHETASE)		 1fsu N-ACETYLGALACTOSAMIN
E-4-SULFATASE
(Homo
sapiens) 		5 / 9 GLY A 308
GLN A 304
ILE A  67
VAL A 270
VAL A 241
 None
 1.34A 3fi0K-1fsuA:
undetectable		 3fi0K-1fsuA:
19.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3FI0_L_TRPL1001_0
(TRYPTOPHANYL-TRNA
SYNTHETASE)		 1fsu N-ACETYLGALACTOSAMIN
E-4-SULFATASE
(Homo
sapiens) 		5 / 9 GLY A 308
GLN A 304
ILE A  67
VAL A 270
VAL A 241
 None
 1.32A 3fi0L-1fsuA:
undetectable		 3fi0L-1fsuA:
19.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3FI0_M_TRPM1001_0
(TRYPTOPHANYL-TRNA
SYNTHETASE)		 1fsu N-ACETYLGALACTOSAMIN
E-4-SULFATASE
(Homo
sapiens) 		5 / 9 GLY A 308
GLN A 304
ILE A  67
VAL A 270
VAL A 241
 None
 1.35A 3fi0M-1fsuA:
undetectable		 3fi0M-1fsuA:
19.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3FI0_N_TRPN1001_0
(TRYPTOPHANYL-TRNA
SYNTHETASE)		 1fsu N-ACETYLGALACTOSAMIN
E-4-SULFATASE
(Homo
sapiens) 		5 / 9 GLY A 308
GLN A 304
ILE A  67
VAL A 270
VAL A 241
 None
 1.27A 3fi0N-1fsuA:
undetectable		 3fi0N-1fsuA:
19.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3FI0_O_TRPO1001_0
(TRYPTOPHANYL-TRNA
SYNTHETASE)		 1fsu N-ACETYLGALACTOSAMIN
E-4-SULFATASE
(Homo
sapiens) 		5 / 9 GLY A 308
GLN A 304
ILE A  67
VAL A 270
VAL A 241
 None
 1.32A 3fi0O-1fsuA:
undetectable		 3fi0O-1fsuA:
19.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3LXI_A_CAMA423_0
(CYTOCHROME P450)		 1fsu N-ACETYLGALACTOSAMIN
E-4-SULFATASE
(Homo
sapiens) 		5 / 10 THR A 368
THR A 107
LEU A 371
GLY A 101
VAL A 122
 None
 1.28A 3lxiA-1fsuA:
undetectable		 3lxiA-1fsuA:
23.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3LXI_B_CAMB423_0
(CYTOCHROME P450)		 1fsu N-ACETYLGALACTOSAMIN
E-4-SULFATASE
(Homo
sapiens) 		5 / 11 THR A 368
THR A 107
LEU A 371
GLY A 101
VAL A 122
 None
 1.29A 3lxiB-1fsuA:
undetectable		 3lxiB-1fsuA:
23.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ZTV_A_ADNA1600_1
(NAD NUCLEOTIDASE)		 1fsu N-ACETYLGALACTOSAMIN
E-4-SULFATASE
(Homo
sapiens) 		5 / 9 ASN A 301
GLY A 302
GLY A 303
SER A 320
GLY A 325
 CA  A 604 ( 2.9A)
None
None
None
None
 1.32A 3ztvA-1fsuA:
undetectable		 3ztvA-1fsuA:
20.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4C9N_B_CAMB1420_0
(CYTOCHROME P450)		 1fsu N-ACETYLGALACTOSAMIN
E-4-SULFATASE
(Homo
sapiens) 		5 / 10 THR A 368
THR A 107
LEU A 371
GLY A 101
VAL A 122
 None
 1.27A 4c9nB-1fsuA:
undetectable		 4c9nB-1fsuA:
23.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4C9P_A_CAMA423_0
(CYTOCHROME P450)		 1fsu N-ACETYLGALACTOSAMIN
E-4-SULFATASE
(Homo
sapiens) 		5 / 9 THR A 368
THR A 107
LEU A 371
GLY A 101
VAL A 122
 None
 1.23A 4c9pA-1fsuA:
undetectable		 4c9pA-1fsuA:
22.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4C9P_B_CAMB423_0
(CYTOCHROME P450)		 1fsu N-ACETYLGALACTOSAMIN
E-4-SULFATASE
(Homo
sapiens) 		5 / 10 THR A 368
THR A 107
LEU A 371
GLY A 101
VAL A 122
 None
 1.20A 4c9pB-1fsuA:
0.0		 4c9pB-1fsuA:
22.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4EJG_B_NCTB501_1
(CYTOCHROME P450 2A13)		 1fsu N-ACETYLGALACTOSAMIN
E-4-SULFATASE
(Homo
sapiens) 		4 / 8 PHE A 162
ALA A 237
LEU A  98
LEU A  99
 None
 0.84A 4ejgB-1fsuA:
undetectable		 4ejgB-1fsuA:
22.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4HTF_A_SAMA301_0
(S-ADENOSYLMETHIONINE
-DEPENDENT
METHYLTRANSFERASE)		 1fsu N-ACETYLGALACTOSAMIN
E-4-SULFATASE
(Homo
sapiens) 		6 / 12 GLY A 325
GLY A 324
GLY A 316
LEU A 321
GLN A  88
TRP A 319
 None
None
None
CL  A 605 ( 4.5A)
None
None
 1.21A 4htfA-1fsuA:
undetectable		 4htfA-1fsuA:
20.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4HTF_B_SAMB301_0
(S-ADENOSYLMETHIONINE
-DEPENDENT
METHYLTRANSFERASE)		 1fsu N-ACETYLGALACTOSAMIN
E-4-SULFATASE
(Homo
sapiens) 		6 / 12 GLY A 325
GLY A 324
GLY A 316
LEU A 321
GLN A  88
TRP A 319
 None
None
None
CL  A 605 ( 4.5A)
None
None
 1.12A 4htfB-1fsuA:
undetectable		 4htfB-1fsuA:
20.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4IK7_A_IMNA201_1
(TRANSTHYRETIN)		 1fsu N-ACETYLGALACTOSAMIN
E-4-SULFATASE
(Homo
sapiens) 		4 / 7 LEU A 392
ALA A 431
THR A 442
VAL A 429
 None
None
None
NAG  A 602 (-4.2A)
 0.94A 4ik7A-1fsuA:
0.0		 4ik7A-1fsuA:
13.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4L4A_A_CAMA502_0
(CAMPHOR
5-MONOOXYGENASE)		 1fsu N-ACETYLGALACTOSAMIN
E-4-SULFATASE
(Homo
sapiens) 		4 / 8 PHE A 297
THR A  69
THR A 299
VAL A 241
 None
 0.84A 4l4aA-1fsuA:
0.0		 4l4aA-1fsuA:
21.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4L4D_A_CAMA503_0
(CAMPHOR
5-MONOOXYGENASE)		 1fsu N-ACETYLGALACTOSAMIN
E-4-SULFATASE
(Homo
sapiens) 		4 / 8 PHE A 297
THR A  69
THR A 299
VAL A 241
 None
 0.81A 4l4dA-1fsuA:
undetectable		 4l4dA-1fsuA:
21.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4L4E_A_CAMA503_0
(CAMPHOR
5-MONOOXYGENASE)		 1fsu N-ACETYLGALACTOSAMIN
E-4-SULFATASE
(Homo
sapiens) 		4 / 8 PHE A 297
THR A  69
THR A 299
VAL A 241
 None
 0.87A 4l4eA-1fsuA:
undetectable		 4l4eA-1fsuA:
21.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4L4F_A_CAMA503_0
(CAMPHOR
5-MONOOXYGENASE)		 1fsu N-ACETYLGALACTOSAMIN
E-4-SULFATASE
(Homo
sapiens) 		4 / 8 PHE A 297
THR A  69
THR A 299
VAL A 241
 None
 0.89A 4l4fA-1fsuA:
undetectable		 4l4fA-1fsuA:
21.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4NDN_C_SAMC405_0
(S-ADENOSYLMETHIONINE
SYNTHASE ISOFORM
TYPE-2)		 1fsu N-ACETYLGALACTOSAMIN
E-4-SULFATASE
(Homo
sapiens) 		4 / 7 PRO A 355
ASP A 375
SER A 384
ASP A 352
 None
 1.31A 4ndnC-1fsuA:
undetectable		 4ndnC-1fsuA:
22.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4OT2_A_NPSA601_1
(SERUM ALBUMIN)		 1fsu N-ACETYLGALACTOSAMIN
E-4-SULFATASE
(Homo
sapiens) 		5 / 12 ASN A 301
TYR A 266
VAL A 329
GLY A 328
SER A 298
 CA  A 604 ( 2.9A)
None
None
None
None
 1.05A 4ot2A-1fsuA:
undetectable		 4ot2A-1fsuA:
22.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QWP_B_GCSB307_1
(CHITOSANASE)		 1fsu N-ACETYLGALACTOSAMIN
E-4-SULFATASE
(Homo
sapiens) 		4 / 7 GLU A 201
ARG A 159
GLY A 199
THR A 158
 None
 0.92A 4qwpB-1fsuA:
0.0		 4qwpB-1fsuA:
20.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4YB6_A_HISA302_0
(ATP
PHOSPHORIBOSYLTRANSF
ERASE)		 1fsu N-ACETYLGALACTOSAMIN
E-4-SULFATASE
(Homo
sapiens) 		5 / 10 GLY A 278
VAL A 277
VAL A 280
LEU A 272
LEU A 236
 None
 1.27A 4yb6A-1fsuA:
0.4
4yb6E-1fsuA:
0.4		 4yb6A-1fsuA:
19.96
4yb6E-1fsuA:
19.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4YB6_B_HISB302_0
(ATP
PHOSPHORIBOSYLTRANSF
ERASE)		 1fsu N-ACETYLGALACTOSAMIN
E-4-SULFATASE
(Homo
sapiens) 		5 / 10 GLY A 278
VAL A 277
VAL A 280
LEU A 272
LEU A 236
 None
 1.27A 4yb6B-1fsuA:
0.4
4yb6C-1fsuA:
0.4		 4yb6B-1fsuA:
19.96
4yb6C-1fsuA:
19.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4YB6_F_HISF302_0
(ATP
PHOSPHORIBOSYLTRANSF
ERASE)		 1fsu N-ACETYLGALACTOSAMIN
E-4-SULFATASE
(Homo
sapiens) 		5 / 10 LEU A 272
LEU A 236
GLY A 278
VAL A 277
VAL A 280
 None
 1.27A 4yb6B-1fsuA:
0.4
4yb6F-1fsuA:
0.4		 4yb6B-1fsuA:
19.96
4yb6F-1fsuA:
19.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4Z2E_F_TR6F101_1
(DNA GYRASE SUBUNIT A
DNA GYRASE SUBUNIT B
SYMMETRIZED E-SITE
DNA)		 1fsu N-ACETYLGALACTOSAMIN
E-4-SULFATASE
(Homo
sapiens) 		4 / 5 GLY A 328
ARG A 327
GLY A 324
GLU A 323
 None
 1.14A 4z2eB-1fsuA:
0.0
4z2eC-1fsuA:
undetectable		 4z2eB-1fsuA:
20.58
4z2eC-1fsuA:
18.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4Z2E_F_TR6F101_1
(DNA GYRASE SUBUNIT A
DNA GYRASE SUBUNIT B
SYMMETRIZED E-SITE
DNA)		 1fsu N-ACETYLGALACTOSAMIN
E-4-SULFATASE
(Homo
sapiens) 		4 / 5 GLY A 328
ARG A 327
GLY A 325
GLU A 323
 None
 1.14A 4z2eB-1fsuA:
0.0
4z2eC-1fsuA:
undetectable		 4z2eB-1fsuA:
20.58
4z2eC-1fsuA:
18.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5AJQ_A_DB8A800_2
(SERINE/THREONINE-PRO
TEIN KINASE 10)		 1fsu N-ACETYLGALACTOSAMIN
E-4-SULFATASE
(Homo
sapiens) 		4 / 4 VAL A 241
ILE A  67
ASN A 311
VAL A 329
 None
 1.32A 5ajqA-1fsuA:
0.0		 5ajqA-1fsuA:
22.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5NNA_A_BZMA301_0
(ISATIN HYDROLASE A)		 1fsu N-ACETYLGALACTOSAMIN
E-4-SULFATASE
(Homo
sapiens) 		5 / 12 ILE A 350
GLY A 101
ASP A 372
GLY A 373
TYR A 103
 None
 1.25A 5nnaA-1fsuA:
0.0		 5nnaA-1fsuA:
18.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5NNA_D_BZMD301_0
(ISATIN HYDROLASE A)		 1fsu N-ACETYLGALACTOSAMIN
E-4-SULFATASE
(Homo
sapiens) 		5 / 12 ILE A 350
GLY A 101
ASP A 372
GLY A 373
TYR A 103
 None
 1.23A 5nnaD-1fsuA:
undetectable		 5nnaD-1fsuA:
18.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5OEX_A_CUA602_0
(THIOCYANATE
DEHYDROGENASE)		 1fsu N-ACETYLGALACTOSAMIN
E-4-SULFATASE
(Homo
sapiens) 		3 / 3 LYS A 261
HIS A 265
HIS A 264
 None
 1.11A 5oexA-1fsuA:
0.0		 5oexA-1fsuA:
22.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5OEX_B_CUB602_0
(THIOCYANATE
DEHYDROGENASE)		 1fsu N-ACETYLGALACTOSAMIN
E-4-SULFATASE
(Homo
sapiens) 		3 / 3 LYS A 261
HIS A 265
HIS A 264
 None
 1.11A 5oexB-1fsuA:
0.0		 5oexB-1fsuA:
22.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5OEX_C_CUC603_0
(THIOCYANATE
DEHYDROGENASE)		 1fsu N-ACETYLGALACTOSAMIN
E-4-SULFATASE
(Homo
sapiens) 		3 / 3 LYS A 261
HIS A 265
HIS A 264
 None
 1.09A 5oexC-1fsuA:
0.0		 5oexC-1fsuA:
22.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5OEX_D_CUD603_0
(THIOCYANATE
DEHYDROGENASE)		 1fsu N-ACETYLGALACTOSAMIN
E-4-SULFATASE
(Homo
sapiens) 		3 / 3 LYS A 261
HIS A 265
HIS A 264
 None
 1.10A 5oexD-1fsuA:
0.0		 5oexD-1fsuA:
22.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VKQ_B_PCFB1804_0
(NO MECHANORECEPTOR
POTENTIAL C ISOFORM
L)		 1fsu N-ACETYLGALACTOSAMIN
E-4-SULFATASE
(Homo
sapiens) 		5 / 8 GLY A  79
LEU A 337
VAL A 294
ILE A 380
LEU A  82
 None
 1.12A 5vkqB-1fsuA:
undetectable
5vkqC-1fsuA:
undetectable		 5vkqB-1fsuA:
15.08
5vkqC-1fsuA:
15.08