SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '1ft5'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)

Filter list by:

	DrReposER ID / Desc.	Hit PDBID	Hit Macromolecule	Res. Matches	Interface	HETATM	RMSD	Dali Z-score	Seq. Identity (%)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2C8A_B_NCAB1246_0 (MONO-ADP-RIBOSYLTRAN SFERASE C3)	1ft5	CYTOCHROME C554 (Nitrosomonas europaea)	4 / 7	ARG A 8 GLY A 85 SER A 90 GLU A 89	PO4 A 218 (-3.8A) None HEM A 216 (-3.9A) None	1.04A	2c8aB-1ft5A: undetectable	2c8aB-1ft5A: 19.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2C8A_D_NCAD1247_0 (MONO-ADP-RIBOSYLTRAN SFERASE C3)	1ft5	CYTOCHROME C554 (Nitrosomonas europaea)	4 / 7	ARG A 8 GLY A 85 SER A 90 GLU A 89	PO4 A 218 (-3.8A) None HEM A 216 (-3.9A) None	1.02A	2c8aD-1ft5A: undetectable	2c8aD-1ft5A: 19.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2IVU_A_ZD6A3015_1 (PROTO-ONCOGENE TYROSINE-PROTEIN KINASE RECEPTOR RET PRECURSOR)	1ft5	CYTOCHROME C554 (Nitrosomonas europaea)	3 / 3	ALA A 30 GLY A 62 SER A 90	HEM A 216 (-3.9A) None HEM A 216 (-3.9A)	0.53A	2ivuA-1ft5A: undetectable	2ivuA-1ft5A: 22.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3AOC_C_ERYC3402_1 (ACRIFLAVINE RESISTANCE PROTEIN B)	1ft5	CYTOCHROME C554 (Nitrosomonas europaea)	3 / 3	THR A 55 SER A 33 LYS A 43	None HEM A 216 ( 2.4A) HEM A 214 ( 4.8A)	1.18A	3aocC-1ft5A: undetectable	3aocC-1ft5A: 11.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	6FGD_A_ACTA819_0 (GEPHYRIN)	1ft5	CYTOCHROME C554 (Nitrosomonas europaea)	3 / 3	ARG A 133 GLY A 93 GLU A 89	None	0.62A	6fgdA-1ft5A: undetectable	6fgdA-1ft5A: 18.07

[["DrReposER ID","Desc.","Hit PDB","Hit molecule","Hit organism","Res. no.","Interface","HETATM","RMSD","Z-score","Seq ID"],["2C8A_B_NCAB1246_0","MONO-ADP-RIBOSYLTRANSFERASE C3","1ft5","CYTOCHROME C554","Nitrosomonas europaea",4,"ARG A   8;GLY A  85;SER A  90;GLU A  89","PO4 A 218 (-3.8A);None;HEM A 216 (-3.9A);None","1.04A","2c8aB-1ft5A:undetectable","2c8aB-1ft5A:19.38"],["2C8A_D_NCAD1247_0","MONO-ADP-RIBOSYLTRANSFERASE C3","1ft5","CYTOCHROME C554","Nitrosomonas europaea",4,"ARG A   8;GLY A  85;SER A  90;GLU A  89","PO4 A 218 (-3.8A);None;HEM A 216 (-3.9A);None","1.02A","2c8aD-1ft5A:undetectable","2c8aD-1ft5A:19.38"],["2IVU_A_ZD6A3015_1","PROTO-ONCOGENE TYROSINE-PROTEIN KINASE RECEPTOR RET PRECURSOR","1ft5","CYTOCHROME C554","Nitrosomonas europaea",3,"ALA A  30;GLY A  62;SER A  90","HEM A 216 (-3.9A);None;HEM A 216 (-3.9A)","0.53A","2ivuA-1ft5A:undetectable","2ivuA-1ft5A:22.19"],["3AOC_C_ERYC3402_1","ACRIFLAVINE RESISTANCE PROTEIN B","1ft5","CYTOCHROME C554","Nitrosomonas europaea",3,"THR A  55;SER A  33;LYS A  43","None;HEM A 216 ( 2.4A);HEM A 214 ( 4.8A)","1.18A","3aocC-1ft5A:undetectable","3aocC-1ft5A:11.38"],["6FGD_A_ACTA819_0","GEPHYRIN","1ft5","CYTOCHROME C554","Nitrosomonas europaea",3,"ARG A 133;GLY A  93;GLU A  89","None","0.62A","6fgdA-1ft5A:undetectable","6fgdA-1ft5A:18.07"]]