SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '1ft9'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1FXH_B_PACB1001_0
(PENICILLIN ACYLASE)		 1ft9 CARBON MONOXIDE
OXIDATION SYSTEM
TRANSCRIPTION
REGULATOR
(Rhodospirillum
rubrum) 		4 / 7 MET A 108
PHE A  19
PHE A  98
ILE A   7
 None
None
HEM  A 300 (-4.8A)
None
 1.04A 1fxhA-1ft9A:
0.0
1fxhB-1ft9A:
0.0		 1fxhA-1ft9A:
21.60
1fxhB-1ft9A:
17.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1PNL_B_PACB559_0
(PENICILLIN
AMIDOHYDROLASE)		 1ft9 CARBON MONOXIDE
OXIDATION SYSTEM
TRANSCRIPTION
REGULATOR
(Rhodospirillum
rubrum) 		4 / 8 MET A 108
PHE A  19
PHE A  98
ILE A   7
 None
None
HEM  A 300 (-4.8A)
None
 1.06A 1pnlA-1ft9A:
0.0
1pnlB-1ft9A:
0.0		 1pnlA-1ft9A:
21.60
1pnlB-1ft9A:
17.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1Q8J_B_C2FB802_0
(5-METHYLTETRAHYDROFO
LATE S-HOMOCYSTEINE
METHYLTRANSFERASE)		 1ft9 CARBON MONOXIDE
OXIDATION SYSTEM
TRANSCRIPTION
REGULATOR
(Rhodospirillum
rubrum) 		5 / 12 GLU A  89
GLY A  71
SER A  32
SER A  25
ILE A  27
 None
 1.15A 1q8jB-1ft9A:
undetectable		 1q8jB-1ft9A:
17.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ETE_A_H3PA552_1
(GLUTAMATE
DEHYDROGENASE)		 1ft9 CARBON MONOXIDE
OXIDATION SYSTEM
TRANSCRIPTION
REGULATOR
(Rhodospirillum
rubrum) 		4 / 6 ILE A 139
TYR A 192
ILE A 144
HIS A 146
 None
 1.06A 3eteA-1ft9A:
undetectable
3eteE-1ft9A:
undetectable		 3eteA-1ft9A:
18.33
3eteE-1ft9A:
18.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ETE_C_H3PC554_1
(GLUTAMATE
DEHYDROGENASE)		 1ft9 CARBON MONOXIDE
OXIDATION SYSTEM
TRANSCRIPTION
REGULATOR
(Rhodospirillum
rubrum) 		4 / 5 ILE A 139
TYR A 192
ILE A 144
HIS A 146
 None
 1.04A 3eteB-1ft9A:
undetectable
3eteC-1ft9A:
undetectable		 3eteB-1ft9A:
18.33
3eteC-1ft9A:
18.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ETE_F_H3PF552_1
(GLUTAMATE
DEHYDROGENASE)		 1ft9 CARBON MONOXIDE
OXIDATION SYSTEM
TRANSCRIPTION
REGULATOR
(Rhodospirillum
rubrum) 		4 / 7 ILE A 144
HIS A 146
ILE A 139
TYR A 192
 None
 1.06A 3eteD-1ft9A:
undetectable
3eteF-1ft9A:
undetectable		 3eteD-1ft9A:
18.33
3eteF-1ft9A:
18.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4EJJ_D_NCTD501_1
(CYTOCHROME P450 2A6)		 1ft9 CARBON MONOXIDE
OXIDATION SYSTEM
TRANSCRIPTION
REGULATOR
(Rhodospirillum
rubrum) 		4 / 7 GLY A 199
ILE A 169
LEU A 184
PHE A 143
 None
 0.82A 4ejjD-1ft9A:
0.0		 4ejjD-1ft9A:
17.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4HB8_A_DXCA75_0
(PPCA)		 1ft9 CARBON MONOXIDE
OXIDATION SYSTEM
TRANSCRIPTION
REGULATOR
(Rhodospirillum
rubrum) 		4 / 8 ILE A 139
LEU A 184
ILE A 203
GLY A 199
 None
 0.76A 4hb8A-1ft9A:
undetectable		 4hb8A-1ft9A:
14.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6GTQ_A_ACTA204_0
(N-ACETYLTRANSFERASE)		 1ft9 CARBON MONOXIDE
OXIDATION SYSTEM
TRANSCRIPTION
REGULATOR
(Rhodospirillum
rubrum) 		4 / 5 LEU A  81
THR A  36
CYH A  80
GLY A  37
 None
 1.16A 6gtqA-1ft9A:
undetectable		 6gtqA-1ft9A:
20.94