SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '1ftf'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1SGU_B_MK1B2632_1
(POL POLYPROTEIN)		 1ftf ACYL CARRIER PROTEIN
SYNTHASE
(Streptococcus
pneumoniae) 		5 / 8 ALA A1061
ILE A1070
GLY A1069
PRO A1094
ALA A1093
 None
 1.01A 1sguA-1ftfA:
undetectable		 1sguA-1ftfA:
24.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1XDK_B_9CRB600_2
(RETINOIC ACID
RECEPTOR, BETA)		 1ftf ACYL CARRIER PROTEIN
SYNTHASE
(Streptococcus
pneumoniae) 		3 / 3 LEU A1032
PHE A1040
ARG A1023
 None
 0.89A 1xdkB-1ftfA:
undetectable		 1xdkB-1ftfA:
15.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ITA_D_AICD501_1
(D-ALANYL-D-ALANINE
CARBOXYPEPTIDASE
DACC)		 1ftf ACYL CARRIER PROTEIN
SYNTHASE
(Streptococcus
pneumoniae) 		3 / 3 PRO A1088
PHE A1090
ALA A1058
 None
 0.37A 3itaD-1ftfA:
undetectable		 3itaD-1ftfA:
15.86