SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '1ftg'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1BU5_A_RBFA301_1
(PROTEIN (FLAVODOXIN))		 1ftg APOFLAVODOXIN
(Nostoc
sp.
PCC
7119) 		5 / 7 THR A  12
THR A  56
GLY A  89
ASP A  90
TYR A  94
 SO4  A 700 (-3.7A)
None
None
None
None
 0.74A 1bu5A-1ftgA:
20.3		 1bu5A-1ftgA:
31.14
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1BU5_B_RBFB302_1
(PROTEIN (FLAVODOXIN))		 1ftg APOFLAVODOXIN
(Nostoc
sp.
PCC
7119) 		4 / 8 THR A  12
GLY A  89
ASP A  90
TYR A  94
 SO4  A 700 (-3.7A)
None
None
None
 0.73A 1bu5B-1ftgA:
20.2		 1bu5B-1ftgA:
31.14
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1BU5_B_RBFB302_1
(PROTEIN (FLAVODOXIN))		 1ftg APOFLAVODOXIN
(Nostoc
sp.
PCC
7119) 		4 / 8 THR A  12
THR A  56
GLY A  89
ASP A  90
 SO4  A 700 (-3.7A)
None
None
None
 0.48A 1bu5B-1ftgA:
20.2		 1bu5B-1ftgA:
31.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1NX9_D_AICD5004_1
(ALPHA-AMINO ACID
ESTER HYDROLASE)		 1ftg APOFLAVODOXIN
(Nostoc
sp.
PCC
7119) 		4 / 8 TYR A 125
GLU A 145
GLN A  99
SER A  17
 None
 1.24A 1nx9D-1ftgA:
2.1		 1nx9D-1ftgA:
13.10
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2Q6O_B_SAMB500_0
(HYPOTHETICAL PROTEIN)		 1ftg APOFLAVODOXIN
(Nostoc
sp.
PCC
7119) 		4 / 6 ASP A  35
VAL A  36
THR A  15
TRP A  66
 None
None
SO4  A 700 (-3.6A)
None
 1.30A 2q6oB-1ftgA:
2.7		 2q6oB-1ftgA:
21.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2YVL_A_SAMA601_0
(HYPOTHETICAL PROTEIN)		 1ftg APOFLAVODOXIN
(Nostoc
sp.
PCC
7119) 		5 / 12 GLY A  53
GLY A  87
ALA A  19
VAL A  18
PHE A   7
 None
 0.92A 2yvlA-1ftgA:
undetectable		 2yvlA-1ftgA:
23.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2YVL_B_SAMB602_0
(HYPOTHETICAL PROTEIN)		 1ftg APOFLAVODOXIN
(Nostoc
sp.
PCC
7119) 		5 / 12 GLY A  53
GLY A  87
ALA A  19
VAL A  18
PHE A   7
 None
 0.94A 2yvlB-1ftgA:
undetectable		 2yvlB-1ftgA:
23.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3B0W_B_DGXB1_1
(NUCLEAR RECEPTOR
ROR-GAMMA)		 1ftg APOFLAVODOXIN
(Nostoc
sp.
PCC
7119) 		5 / 12 LEU A 163
CYH A  54
ALA A  19
LEU A  62
LEU A  69
 None
 1.32A 3b0wB-1ftgA:
undetectable		 3b0wB-1ftgA:
19.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3GWW_A_SFXA801_1
(TRANSPORTER)		 1ftg APOFLAVODOXIN
(Nostoc
sp.
PCC
7119) 		5 / 12 GLY A 168
LEU A 169
TYR A  49
ILE A   4
PHE A  26
 None
 1.02A 3gwwA-1ftgA:
0.0		 3gwwA-1ftgA:
15.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3OU6_C_SAMC300_1
(SAM-DEPENDENT
METHYLTRANSFERASE)		 1ftg APOFLAVODOXIN
(Nostoc
sp.
PCC
7119) 		3 / 3 TYR A  94
GLY A  89
ASP A 144
 None
 0.73A 3ou6C-1ftgA:
undetectable		 3ou6C-1ftgA:
22.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4MFL_B_GCSB502_1
(PUTATIVE
UNCHARACTERIZED
PROTEIN TCP24
TEICOPLANIN
PSEUDOAGLYCONE)		 1ftg APOFLAVODOXIN
(Nostoc
sp.
PCC
7119) 		4 / 6 GLN A 162
TRP A 159
ALA A  84
PHE A  26
 None
 1.34A 4mflA-1ftgA:
0.0		 4mflA-1ftgA:
18.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4MFQ_B_GCSB503_1
(PUTATIVE
UNCHARACTERIZED
PROTEIN TCP24
TEICOPLANIN
PSEUDOAGLYCONE)		 1ftg APOFLAVODOXIN
(Nostoc
sp.
PCC
7119) 		4 / 6 GLN A 162
TRP A 159
ALA A  84
PHE A  26
 None
 1.32A 4mfqA-1ftgA:
0.0		 4mfqA-1ftgA:
18.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4RET_A_DGXA1107_1
(SODIUM/POTASSIUM-TRA
NSPORTING ATPASE
SUBUNIT ALPHA-1)		 1ftg APOFLAVODOXIN
(Nostoc
sp.
PCC
7119) 		5 / 12 GLU A  16
ALA A  84
GLU A 166
PHE A  86
LEU A 143
 None
 1.17A 4retA-1ftgA:
undetectable		 4retA-1ftgA:
10.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4RET_A_DGXA1107_1
(SODIUM/POTASSIUM-TRA
NSPORTING ATPASE
SUBUNIT ALPHA-1)		 1ftg APOFLAVODOXIN
(Nostoc
sp.
PCC
7119) 		5 / 12 GLU A  20
ALA A  84
GLU A 166
PHE A  86
LEU A 143
 None
 1.14A 4retA-1ftgA:
undetectable		 4retA-1ftgA:
10.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4RET_C_DGXC2005_1
(SODIUM/POTASSIUM-TRA
NSPORTING ATPASE
SUBUNIT ALPHA-1)		 1ftg APOFLAVODOXIN
(Nostoc
sp.
PCC
7119) 		5 / 12 GLU A  16
ALA A  84
GLU A 166
PHE A  86
LEU A 143
 None
 1.17A 4retC-1ftgA:
undetectable		 4retC-1ftgA:
10.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4RET_C_DGXC2005_1
(SODIUM/POTASSIUM-TRA
NSPORTING ATPASE
SUBUNIT ALPHA-1)		 1ftg APOFLAVODOXIN
(Nostoc
sp.
PCC
7119) 		5 / 12 GLU A  20
ALA A  84
GLU A 166
PHE A  86
LEU A 143
 None
 1.14A 4retC-1ftgA:
undetectable		 4retC-1ftgA:
10.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5FCT_B_C2FB402_1
(THYMIDYLATE SYNTHASE)		 1ftg APOFLAVODOXIN
(Nostoc
sp.
PCC
7119) 		3 / 3 ASN A  58
ASP A  65
GLY A   9
 None
 0.65A 5fctB-1ftgA:
0.0		 5fctB-1ftgA:
22.01