SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '1ftp'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1YC2_E_NCAE509_0
(NAD-DEPENDENT
DEACETYLASE 2)		 1ftp MUSCLE FATTY ACID
BINDING PROTEIN
(Schistocerca
gregaria) 		4 / 6 ASP A  89
GLU A 109
ARG A 108
LYS A  93
 None
 1.39A 1yc2A-1ftpA:
undetectable
1yc2B-1ftpA:
undetectable
1yc2E-1ftpA:
undetectable		 1yc2A-1ftpA:
19.66
1yc2B-1ftpA:
19.66
1yc2E-1ftpA:
19.66
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2QM9_A_TDZA201_1
(FATTY ACID-BINDING
PROTEIN, ADIPOCYTE)		 1ftp MUSCLE FATTY ACID
BINDING PROTEIN
(Schistocerca
gregaria) 		6 / 12 PHE A  17
VAL A  26
SER A  55
THR A  62
ARG A 128
TYR A 130
 None
 0.89A 2qm9A-1ftpA:
19.9		 2qm9A-1ftpA:
37.34
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2QM9_A_TDZA201_2
(FATTY ACID-BINDING
PROTEIN, ADIPOCYTE)		 1ftp MUSCLE FATTY ACID
BINDING PROTEIN
(Schistocerca
gregaria) 		4 / 4 TYR A  20
MET A  21
PRO A  39
ILE A 106
 None
 0.73A 2qm9A-1ftpA:
19.9		 2qm9A-1ftpA:
37.34
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2QM9_B_TDZB202_1
(FATTY ACID-BINDING
PROTEIN, ADIPOCYTE)		 1ftp MUSCLE FATTY ACID
BINDING PROTEIN
(Schistocerca
gregaria) 		8 / 12 PHE A  17
TYR A  20
VAL A  26
SER A  55
THR A  62
ILE A 106
ARG A 128
TYR A 130
 None
 0.94A 2qm9B-1ftpA:
20.5		 2qm9B-1ftpA:
37.34
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ARR_A_PNXA607_1
(CHITINASE A)		 1ftp MUSCLE FATTY ACID
BINDING PROTEIN
(Schistocerca
gregaria) 		4 / 7 VAL A  82
SER A  84
HIS A  96
THR A  76
 None
 0.81A 3arrA-1ftpA:
undetectable		 3arrA-1ftpA:
14.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3D91_B_REMB350_1
(RENIN)		 1ftp MUSCLE FATTY ACID
BINDING PROTEIN
(Schistocerca
gregaria) 		5 / 12 ASP A  78
GLY A  79
VAL A  26
SER A  84
HIS A  96
 None
 1.22A 3d91B-1ftpA:
undetectable		 3d91B-1ftpA:
17.52
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3P6G_A_IZPA133_1
(FATTY ACID-BINDING
PROTEIN, ADIPOCYTE)		 1ftp MUSCLE FATTY ACID
BINDING PROTEIN
(Schistocerca
gregaria) 		8 / 12 PHE A  17
MET A  21
VAL A  26
PRO A  39
ILE A 106
ARG A 108
ARG A 128
TYR A 130
 None
 0.87A 3p6gA-1ftpA:
19.9		 3p6gA-1ftpA:
40.85
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3P6H_A_IBPA133_1
(FATTY ACID-BINDING
PROTEIN, ADIPOCYTE)		 1ftp MUSCLE FATTY ACID
BINDING PROTEIN
(Schistocerca
gregaria) 		5 / 7 PHE A  17
MET A  21
ILE A 106
ARG A 128
TYR A 130
 None
 0.83A 3p6hA-1ftpA:
19.9		 3p6hA-1ftpA:
40.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4IIL_A_RBFA401_1
(MEMBRANE LIPOPROTEIN
TPN38(B))		 1ftp MUSCLE FATTY ACID
BINDING PROTEIN
(Schistocerca
gregaria) 		5 / 12 SER A  55
GLN A  14
ALA A 126
GLN A  98
TYR A  20
 None
 1.44A 4iilA-1ftpA:
undetectable		 4iilA-1ftpA:
16.87
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4QZT_A_ACTA202_0
(RETINOL-BINDING
PROTEIN 2)		 1ftp MUSCLE FATTY ACID
BINDING PROTEIN
(Schistocerca
gregaria) 		4 / 6 GLU A  74
THR A  76
LEU A  77
GLN A  98
 None
 0.99A 4qztA-1ftpA:
19.4		 4qztA-1ftpA:
33.57
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4QZT_A_ACTA202_0
(RETINOL-BINDING
PROTEIN 2)		 1ftp MUSCLE FATTY ACID
BINDING PROTEIN
(Schistocerca
gregaria) 		4 / 6 TYR A  20
GLU A  74
LEU A  77
GLN A  98
 None
 0.69A 4qztA-1ftpA:
19.4		 4qztA-1ftpA:
33.57
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4QZT_B_ACTB201_0
(RETINOL-BINDING
PROTEIN 2)		 1ftp MUSCLE FATTY ACID
BINDING PROTEIN
(Schistocerca
gregaria) 		4 / 5 TYR A  20
GLU A  74
LEU A  77
GLN A  98
 None
 0.87A 4qztB-1ftpA:
19.6		 4qztB-1ftpA:
33.57
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4QZU_C_ACTC202_0
(RETINOL-BINDING
PROTEIN 2)		 1ftp MUSCLE FATTY ACID
BINDING PROTEIN
(Schistocerca
gregaria) 		4 / 6 TYR A  20
GLU A  74
THR A  76
GLN A  98
 None
 0.95A 4qzuC-1ftpA:
19.2		 4qzuC-1ftpA:
33.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6FBV_D_FI8D1904_0
(DNA-DIRECTED RNA
POLYMERASE SUBUNIT
BETA
DNA-DIRECTED RNA
POLYMERASE SUBUNIT
BETA')		 1ftp MUSCLE FATTY ACID
BINDING PROTEIN
(Schistocerca
gregaria) 		4 / 8 THR A  87
VAL A  95
LYS A  93
SER A  84
 None
 1.13A 6fbvC-1ftpA:
2.1		 6fbvC-1ftpA:
8.47