SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '1fue'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1BU5_A_RBFA301_1
(PROTEIN (FLAVODOXIN))		 1fue FLAVODOXIN
(Helicobacter
pylori) 		5 / 7 ASN A  14
THR A  54
GLY A  87
ASP A  88
TYR A  92
 FMN  A 165 (-3.6A)
FMN  A 165 (-4.0A)
FMN  A 165 (-3.3A)
None
FMN  A 165 (-3.4A)
 0.63A 1bu5A-1fueA:
18.9		 1bu5A-1fueA:
30.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1BU5_B_RBFB302_1
(PROTEIN (FLAVODOXIN))		 1fue FLAVODOXIN
(Helicobacter
pylori) 		5 / 8 ASN A  14
THR A  54
GLY A  87
ASP A  88
TYR A  92
 FMN  A 165 (-3.6A)
FMN  A 165 (-4.0A)
FMN  A 165 (-3.3A)
None
FMN  A 165 (-3.4A)
 0.61A 1bu5B-1fueA:
18.8		 1bu5B-1fueA:
30.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1HSH_A_MK1A401_1
(HIV-II PROTEASE)		 1fue FLAVODOXIN
(Helicobacter
pylori) 		6 / 12 GLY A  85
ALA A  52
VAL A  34
ILE A   6
ILE A  81
ILE A 103
 None
 1.35A 1hshA-1fueA:
undetectable		 1hshA-1fueA:
18.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1SN5_C_T3C601_2
(TRANSTHYRETIN)		 1fue FLAVODOXIN
(Helicobacter
pylori) 		4 / 8 LEU A  83
THR A  54
ALA A  52
LEU A  50
 None
FMN  A 165 (-4.0A)
None
None
 0.98A 1sn5C-1fueA:
undetectable		 1sn5C-1fueA:
23.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2NXE_A_SAMA302_1
(RIBOSOMAL PROTEIN
L11
METHYLTRANSFERASE)		 1fue FLAVODOXIN
(Helicobacter
pylori) 		3 / 3 THR A 148
ASP A  88
SER A  93
 None
 0.77A 2nxeA-1fueA:
undetectable		 2nxeA-1fueA:
21.01
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2NXE_B_SAMB303_1
(RIBOSOMAL PROTEIN
L11
METHYLTRANSFERASE)		 1fue FLAVODOXIN
(Helicobacter
pylori) 		3 / 3 THR A 148
ASP A  88
SER A  93
 None
 0.76A 2nxeB-1fueA:
2.1		 2nxeB-1fueA:
21.01
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ZZN_A_SAMA401_0
(UNCHARACTERIZED
PROTEIN MJ0883)		 1fue FLAVODOXIN
(Helicobacter
pylori) 		5 / 12 PHE A   7
GLY A   9
ILE A   6
VAL A  48
PHE A  45
 None
 1.16A 2zznA-1fueA:
undetectable		 2zznA-1fueA:
18.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3MEC_A_65BA561_0
(P66 REVERSE
TRANSCRIPTASE)		 1fue FLAVODOXIN
(Helicobacter
pylori) 		5 / 12 LEU A  60
VAL A  34
GLY A   9
PHE A  67
LEU A  68
 None
 1.16A 3mecA-1fueA:
undetectable		 3mecA-1fueA:
15.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3MED_A_65BA561_0
(P51 REVERSE
TRANSCRIPTASE
P66 REVERSE
TRANSCRIPTASE)		 1fue FLAVODOXIN
(Helicobacter
pylori) 		5 / 12 LEU A  60
VAL A  34
GLY A   9
PHE A  67
LEU A  68
 None
 1.15A 3medA-1fueA:
undetectable
3medB-1fueA:
undetectable		 3medA-1fueA:
15.46
3medB-1fueA:
15.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4FR0_A_SAMA401_0
(ARSENIC
METHYLTRANSFERASE)		 1fue FLAVODOXIN
(Helicobacter
pylori) 		5 / 12 GLY A  99
GLY A  58
PHE A 134
ILE A 100
LEU A  86
 None
FMN  A 165 (-3.8A)
None
None
FMN  A 165 (-3.7A)
 1.14A 4fr0A-1fueA:
undetectable		 4fr0A-1fueA:
20.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ODJ_A_SAMA500_0
(S-ADENOSYLMETHIONINE
SYNTHASE)		 1fue FLAVODOXIN
(Helicobacter
pylori) 		4 / 7 ASP A 140
SER A 126
PHE A  96
ASP A  90
 None
 1.26A 4odjA-1fueA:
undetectable		 4odjA-1fueA:
16.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4PWJ_A_30ZA201_1
(TRANSTHYRETIN)		 1fue FLAVODOXIN
(Helicobacter
pylori) 		4 / 6 LEU A  83
THR A  54
ALA A  52
LEU A  50
 None
FMN  A 165 (-4.0A)
None
None
 0.97A 4pwjA-1fueA:
undetectable		 4pwjA-1fueA:
20.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4PWJ_B_30ZB201_1
(TRANSTHYRETIN)		 1fue FLAVODOXIN
(Helicobacter
pylori) 		4 / 7 LEU A  83
THR A  54
ALA A  52
LEU A  50
 None
FMN  A 165 (-4.0A)
None
None
 0.98A 4pwjB-1fueA:
undetectable		 4pwjB-1fueA:
20.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4RTP_A_SAMA301_0
(DNA ADENINE
METHYLASE)		 1fue FLAVODOXIN
(Helicobacter
pylori) 		5 / 12 PHE A 101
GLY A  58
ALA A  57
ILE A 100
TYR A 104
 None
FMN  A 165 (-3.8A)
None
None
None
 1.29A 4rtpA-1fueA:
undetectable		 4rtpA-1fueA:
19.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5A1I_A_SAMA405_0
(S-ADENOSYLMETHIONINE
SYNTHASE ISOFORM
TYPE-2)		 1fue FLAVODOXIN
(Helicobacter
pylori) 		4 / 7 ASP A 140
SER A 126
PHE A  96
ASP A  90
 None
 1.30A 5a1iA-1fueA:
undetectable		 5a1iA-1fueA:
19.74
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B58_C_ACTC609_0
(FUMARATE REDUCTASE
FLAVOPROTEIN SUBUNIT)		 1fue FLAVODOXIN
(Helicobacter
pylori) 		4 / 5 PHE A 101
GLU A  98
ASP A  59
HIS A 102
 None
 1.48A 6b58C-1fueA:
0.3		 6b58C-1fueA:
14.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6G6R_A_SAMA406_0
(S-ADENOSYLMETHIONINE
SYNTHASE ISOFORM
TYPE-2)		 1fue FLAVODOXIN
(Helicobacter
pylori) 		4 / 7 ASP A 140
SER A 126
PHE A  96
ASP A  90
 None
 1.31A 6g6rA-1fueA:
undetectable		 6g6rA-1fueA:
19.74