SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '1fui'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1E7B_A_HLTA4002_1
(SERUM ALBUMIN)		 1fui L-FUCOSE ISOMERASE
(Escherichia
coli) 		4 / 4 ARG A 271
ALA A 267
ALA A 230
GLU A 226
 None
 1.15A 1e7bA-1fuiA:
1.6		 1e7bA-1fuiA:
20.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1E7B_B_HLTB4002_1
(SERUM ALBUMIN)		 1fui L-FUCOSE ISOMERASE
(Escherichia
coli) 		4 / 4 ARG A 271
ALA A 267
ALA A 230
GLU A 226
 None
 1.17A 1e7bB-1fuiA:
undetectable		 1e7bB-1fuiA:
20.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GTN_C_TRPC81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN)		 1fui L-FUCOSE ISOMERASE
(Escherichia
coli) 		5 / 10 ALA A 123
GLY A 109
ALA A 124
THR A  87
ILE A 107
 None
 1.20A 1gtnB-1fuiA:
undetectable
1gtnC-1fuiA:
undetectable		 1gtnB-1fuiA:
8.97
1gtnC-1fuiA:
8.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GTN_I_TRPI81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN)		 1fui L-FUCOSE ISOMERASE
(Escherichia
coli) 		5 / 10 ALA A 123
GLY A 109
ALA A 124
THR A  87
ILE A 107
 None
 1.19A 1gtnH-1fuiA:
undetectable
1gtnI-1fuiA:
0.0		 1gtnH-1fuiA:
8.97
1gtnI-1fuiA:
8.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GTN_M_TRPM81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN)		 1fui L-FUCOSE ISOMERASE
(Escherichia
coli) 		5 / 11 GLY A 109
ALA A 124
THR A  87
ILE A 107
ALA A 123
 None
 1.17A 1gtnM-1fuiA:
undetectable
1gtnN-1fuiA:
undetectable		 1gtnM-1fuiA:
8.97
1gtnN-1fuiA:
8.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ONI_A_BEZA501_0
(14.5 KDA
TRANSLATIONAL
INHIBITOR PROTEIN)		 1fui L-FUCOSE ISOMERASE
(Escherichia
coli) 		4 / 7 PHE A 450
ALA A 396
ILE A 391
PRO A 500
 None
 0.90A 1oniA-1fuiA:
undetectable
1oniB-1fuiA:
undetectable		 1oniA-1fuiA:
13.54
1oniB-1fuiA:
13.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ONI_A_BEZA501_0
(14.5 KDA
TRANSLATIONAL
INHIBITOR PROTEIN)		 1fui L-FUCOSE ISOMERASE
(Escherichia
coli) 		4 / 7 PHE A 514
ALA A 476
ILE A 388
PRO A 506
 None
 1.13A 1oniA-1fuiA:
undetectable
1oniB-1fuiA:
undetectable		 1oniA-1fuiA:
13.54
1oniB-1fuiA:
13.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ONI_H_BEZH515_0
(14.5 KDA
TRANSLATIONAL
INHIBITOR PROTEIN)		 1fui L-FUCOSE ISOMERASE
(Escherichia
coli) 		4 / 6 PHE A 450
ALA A 396
ILE A 391
PRO A 500
 None
 1.10A 1oniH-1fuiA:
undetectable
1oniI-1fuiA:
undetectable		 1oniH-1fuiA:
13.54
1oniI-1fuiA:
13.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ONI_I_BEZI517_0
(14.5 KDA
TRANSLATIONAL
INHIBITOR PROTEIN)		 1fui L-FUCOSE ISOMERASE
(Escherichia
coli) 		4 / 7 ILE A 391
PRO A 500
PHE A 450
ALA A 396
 None
 0.91A 1oniG-1fuiA:
undetectable
1oniI-1fuiA:
undetectable		 1oniG-1fuiA:
13.54
1oniI-1fuiA:
13.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2OAX_B_SNLB2001_1
(MINERALOCORTICOID
RECEPTOR)		 1fui L-FUCOSE ISOMERASE
(Escherichia
coli) 		5 / 12 ALA A 356
GLN A 357
LEU A 531
CYH A 427
PHE A 323
 None
 1.23A 2oaxB-1fuiA:
undetectable		 2oaxB-1fuiA:
17.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2OAX_F_SNLF6001_1
(MINERALOCORTICOID
RECEPTOR)		 1fui L-FUCOSE ISOMERASE
(Escherichia
coli) 		5 / 12 ALA A 356
GLN A 357
LEU A 531
CYH A 427
PHE A 323
 None
 1.21A 2oaxF-1fuiA:
undetectable		 2oaxF-1fuiA:
17.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2OPX_A_DXCA1002_0
(ALDEHYDE
DEHYDROGENASE A)		 1fui L-FUCOSE ISOMERASE
(Escherichia
coli) 		3 / 3 GLY A  17
ARG A  23
TYR A  92
 None
 0.81A 2opxA-1fuiA:
2.5		 2opxA-1fuiA:
22.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2PO5_B_CHDB502_0
(FERROCHELATASE,
MITOCHONDRIAL)		 1fui L-FUCOSE ISOMERASE
(Escherichia
coli) 		4 / 8 MET A 348
LEU A 543
ARG A 548
GLY A 202
 None
 0.90A 2po5B-1fuiA:
4.9		 2po5B-1fuiA:
20.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2VH3_B_DAHB2_1
(RANASMURFIN)		 1fui L-FUCOSE ISOMERASE
(Escherichia
coli) 		4 / 8 ALA A 126
GLY A 132
SER A 565
ALA A 566
 None
 0.86A 2vh3B-1fuiA:
undetectable		 2vh3B-1fuiA:
13.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2W8Y_A_486A1000_2
(PROGESTERONE
RECEPTOR)		 1fui L-FUCOSE ISOMERASE
(Escherichia
coli) 		4 / 7 LEU A 319
ASN A 320
LEU A 347
MET A 346
 None
 1.27A 2w8yA-1fuiA:
0.0		 2w8yA-1fuiA:
16.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3EKW_B_DR7B100_2
(PROTEASE)		 1fui L-FUCOSE ISOMERASE
(Escherichia
coli) 		5 / 12 GLY A 525
ALA A 526
ILE A 187
ILE A 465
ALA A 345
 None
 0.97A 3ekwB-1fuiA:
undetectable		 3ekwB-1fuiA:
10.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3IXL_A_PACA5000_0
(ARYLMALONATE
DECARBOXYLASE)		 1fui L-FUCOSE ISOMERASE
(Escherichia
coli) 		5 / 10 PRO A 411
THR A 452
SER A 480
GLY A 454
GLY A 455
 None
 1.22A 3ixlA-1fuiA:
0.3		 3ixlA-1fuiA:
19.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3RXH_A_HSMA7_1
(CATIONIC TRYPSIN)		 1fui L-FUCOSE ISOMERASE
(Escherichia
coli) 		4 / 5 ASP A 339
SER A 340
VAL A 192
GLY A 189
 None
 1.07A 3rxhA-1fuiA:
undetectable		 3rxhA-1fuiA:
18.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4DXU_A_ACAA711_1
(LACTOTRANSFERRIN)		 1fui L-FUCOSE ISOMERASE
(Escherichia
coli) 		4 / 6 GLY A 478
PRO A 506
GLY A 386
GLU A 384
 None
 0.84A 4dxuA-1fuiA:
undetectable		 4dxuA-1fuiA:
19.34
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4J03_A_FVSA603_1
(BIFUNCTIONAL EPOXIDE
HYDROLASE 2)		 1fui L-FUCOSE ISOMERASE
(Escherichia
coli) 		5 / 12 TYR A 120
ILE A  62
PHE A  75
LEU A  45
LEU A 167
 None
 1.09A 4j03A-1fuiA:
4.1		 4j03A-1fuiA:
22.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4J7U_D_YTZD802_1
(SEPIAPTERIN
REDUCTASE)		 1fui L-FUCOSE ISOMERASE
(Escherichia
coli) 		4 / 8 SER A 401
LEU A 398
CYH A 427
PHE A 323
 None
 1.16A 4j7uD-1fuiA:
2.2		 4j7uD-1fuiA:
18.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4L1A_A_AB1A101_1
(MDR769 HIV-1
PROTEASE)		 1fui L-FUCOSE ISOMERASE
(Escherichia
coli) 		5 / 11 ARG A 548
GLY A 166
ALA A 165
ASP A 539
ILE A 138
 None
 1.01A 4l1aA-1fuiA:
undetectable		 4l1aA-1fuiA:
11.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4LTW_A_STRA301_2
(ANCESTRAL STEROID
RECEPTOR 2)		 1fui L-FUCOSE ISOMERASE
(Escherichia
coli) 		4 / 8 MET A 172
THR A 532
VAL A 536
PHE A 540
 None
 0.87A 4ltwA-1fuiA:
undetectable		 4ltwA-1fuiA:
16.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4P65_K_IPHK101_0
(INSULIN)		 1fui L-FUCOSE ISOMERASE
(Escherichia
coli) 		6 / 12 LEU A  82
VAL A  86
ILE A  11
LEU A  41
LEU A 159
ALA A 163
 None
 1.34A 4p65F-1fuiA:
undetectable
4p65H-1fuiA:
undetectable
4p65K-1fuiA:
undetectable
4p65L-1fuiA:
undetectable		 4p65F-1fuiA:
3.76
4p65H-1fuiA:
3.76
4p65K-1fuiA:
3.09
4p65L-1fuiA:
3.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QWP_B_GCSB307_1
(CHITOSANASE)		 1fui L-FUCOSE ISOMERASE
(Escherichia
coli) 		4 / 7 THR A 353
GLY A 349
THR A 355
VAL A 530
 None
 1.01A 4qwpB-1fuiA:
0.0		 4qwpB-1fuiA:
16.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4R29_A_SAMA301_0
(UNCHARACTERIZED
PROTEIN)		 1fui L-FUCOSE ISOMERASE
(Escherichia
coli) 		5 / 12 SER A 150
ALA A 118
GLY A 109
PHE A 110
TYR A 139
 None
 1.23A 4r29A-1fuiA:
undetectable		 4r29A-1fuiA:
17.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4R29_C_SAMC301_0
(UNCHARACTERIZED
PROTEIN)		 1fui L-FUCOSE ISOMERASE
(Escherichia
coli) 		5 / 12 SER A 150
ALA A 118
GLY A 109
PHE A 110
TYR A 139
 None
 1.25A 4r29C-1fuiA:
0.1		 4r29C-1fuiA:
17.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4UUU_A_SAMA1546_0
(CYSTATHIONINE
BETA-SYNTHASE)		 1fui L-FUCOSE ISOMERASE
(Escherichia
coli) 		5 / 11 ASP A  98
ALA A  68
VAL A  14
THR A  85
ILE A  84
 None
 1.38A 4uuuA-1fuiA:
0.0
4uuuB-1fuiA:
0.0		 4uuuA-1fuiA:
14.16
4uuuB-1fuiA:
14.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4YHA_B_MZMB303_1
(ALPHA-CARBONIC
ANHYDRASE)		 1fui L-FUCOSE ISOMERASE
(Escherichia
coli) 		5 / 10 ASP A 154
VAL A 155
LEU A  40
THR A  37
ALA A  36
 None
 1.44A 4yhaB-1fuiA:
undetectable		 4yhaB-1fuiA:
16.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4Z69_A_DIFA1007_1
(SERUM ALBUMIN)		 1fui L-FUCOSE ISOMERASE
(Escherichia
coli) 		5 / 9 ARG A 494
LEU A 491
LEU A 379
ILE A 387
ALA A 370
 None
 1.35A 4z69A-1fuiA:
1.7		 4z69A-1fuiA:
20.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEU_F_TRPF101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 1fui L-FUCOSE ISOMERASE
(Escherichia
coli) 		5 / 10 ALA A 123
GLY A 109
ALA A 124
THR A  87
ILE A 107
 None
 1.19A 5eeuF-1fuiA:
0.0
5eeuG-1fuiA:
undetectable		 5eeuF-1fuiA:
8.97
5eeuG-1fuiA:
8.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEV_F_TRPF101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 1fui L-FUCOSE ISOMERASE
(Escherichia
coli) 		5 / 10 ALA A 123
GLY A 109
ALA A 124
THR A  87
ILE A 107
 None
 1.19A 5eevF-1fuiA:
0.0
5eevG-1fuiA:
0.0		 5eevF-1fuiA:
8.97
5eevG-1fuiA:
8.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEV_P_TRPP101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 1fui L-FUCOSE ISOMERASE
(Escherichia
coli) 		5 / 10 GLY A 109
ALA A 124
THR A  87
ILE A 107
ALA A 123
 None
 1.22A 5eevO-1fuiA:
undetectable
5eevP-1fuiA:
undetectable		 5eevO-1fuiA:
8.97
5eevP-1fuiA:
8.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEW_F_TRPF101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 1fui L-FUCOSE ISOMERASE
(Escherichia
coli) 		5 / 10 ALA A 123
GLY A 109
ALA A 124
THR A  87
ILE A 107
 None
 1.19A 5eewF-1fuiA:
0.0
5eewG-1fuiA:
undetectable		 5eewF-1fuiA:
8.97
5eewG-1fuiA:
8.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEW_P_TRPP101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 1fui L-FUCOSE ISOMERASE
(Escherichia
coli) 		5 / 10 GLY A 109
ALA A 124
THR A  87
ILE A 107
ALA A 123
 None
 1.22A 5eewO-1fuiA:
undetectable
5eewP-1fuiA:
undetectable		 5eewO-1fuiA:
8.97
5eewP-1fuiA:
8.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEX_F_TRPF101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 1fui L-FUCOSE ISOMERASE
(Escherichia
coli) 		5 / 10 ALA A 123
GLY A 109
ALA A 124
THR A  87
ILE A 107
 None
 1.19A 5eexF-1fuiA:
undetectable
5eexG-1fuiA:
0.0		 5eexF-1fuiA:
8.97
5eexG-1fuiA:
8.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEX_P_TRPP101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 1fui L-FUCOSE ISOMERASE
(Escherichia
coli) 		5 / 10 GLY A 109
ALA A 124
THR A  87
ILE A 107
ALA A 123
 None
 1.22A 5eexO-1fuiA:
undetectable
5eexP-1fuiA:
undetectable		 5eexO-1fuiA:
8.97
5eexP-1fuiA:
8.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEY_F_TRPF101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 1fui L-FUCOSE ISOMERASE
(Escherichia
coli) 		5 / 10 ALA A 123
GLY A 109
ALA A 124
THR A  87
ILE A 107
 None
 1.19A 5eeyF-1fuiA:
undetectable
5eeyG-1fuiA:
undetectable		 5eeyF-1fuiA:
8.97
5eeyG-1fuiA:
8.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEZ_F_TRPF101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 1fui L-FUCOSE ISOMERASE
(Escherichia
coli) 		5 / 10 ALA A 123
GLY A 109
ALA A 124
THR A  87
ILE A 107
 None
 1.19A 5eezF-1fuiA:
undetectable
5eezG-1fuiA:
0.0		 5eezF-1fuiA:
8.97
5eezG-1fuiA:
8.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF0_F_TRPF101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 1fui L-FUCOSE ISOMERASE
(Escherichia
coli) 		5 / 10 ALA A 123
GLY A 109
ALA A 124
THR A  87
ILE A 107
 None
 1.19A 5ef0F-1fuiA:
undetectable
5ef0G-1fuiA:
0.0		 5ef0F-1fuiA:
8.97
5ef0G-1fuiA:
8.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF0_P_TRPP101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 1fui L-FUCOSE ISOMERASE
(Escherichia
coli) 		5 / 10 GLY A 109
ALA A 124
THR A  87
ILE A 107
ALA A 123
 None
 1.22A 5ef0O-1fuiA:
undetectable
5ef0P-1fuiA:
undetectable		 5ef0O-1fuiA:
8.97
5ef0P-1fuiA:
8.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF1_F_TRPF101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 1fui L-FUCOSE ISOMERASE
(Escherichia
coli) 		5 / 10 ALA A 123
GLY A 109
ALA A 124
THR A  87
ILE A 107
 None
 1.19A 5ef1F-1fuiA:
undetectable
5ef1G-1fuiA:
0.0		 5ef1F-1fuiA:
8.97
5ef1G-1fuiA:
8.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF1_P_TRPP101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 1fui L-FUCOSE ISOMERASE
(Escherichia
coli) 		5 / 10 GLY A 109
ALA A 124
THR A  87
ILE A 107
ALA A 123
 None
 1.22A 5ef1O-1fuiA:
undetectable
5ef1P-1fuiA:
undetectable		 5ef1O-1fuiA:
8.97
5ef1P-1fuiA:
8.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF2_F_TRPF101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 1fui L-FUCOSE ISOMERASE
(Escherichia
coli) 		5 / 10 ALA A 123
GLY A 109
ALA A 124
THR A  87
ILE A 107
 None
 1.19A 5ef2F-1fuiA:
0.0
5ef2G-1fuiA:
0.0		 5ef2F-1fuiA:
8.97
5ef2G-1fuiA:
8.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF2_P_TRPP101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 1fui L-FUCOSE ISOMERASE
(Escherichia
coli) 		5 / 10 GLY A 109
ALA A 124
THR A  87
ILE A 107
ALA A 123
 None
 1.22A 5ef2O-1fuiA:
undetectable
5ef2P-1fuiA:
undetectable		 5ef2O-1fuiA:
8.97
5ef2P-1fuiA:
8.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF3_F_TRPF101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 1fui L-FUCOSE ISOMERASE
(Escherichia
coli) 		5 / 10 ALA A 123
GLY A 109
ALA A 124
THR A  87
ILE A 107
 None
 1.19A 5ef3F-1fuiA:
undetectable
5ef3G-1fuiA:
0.0		 5ef3F-1fuiA:
8.97
5ef3G-1fuiA:
8.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF3_P_TRPP101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 1fui L-FUCOSE ISOMERASE
(Escherichia
coli) 		5 / 10 GLY A 109
ALA A 124
THR A  87
ILE A 107
ALA A 123
 None
 1.22A 5ef3O-1fuiA:
undetectable
5ef3P-1fuiA:
undetectable		 5ef3O-1fuiA:
8.97
5ef3P-1fuiA:
8.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5LG3_A_Z80A401_1
(GAMMA-AMINOBUTYRIC-A
CID RECEPTOR SUBUNIT
BETA-1)		 1fui L-FUCOSE ISOMERASE
(Escherichia
coli) 		5 / 11 ILE A 107
ILE A  97
THR A  83
ASP A 100
ALA A  68
 None
 1.08A 5lg3A-1fuiA:
0.0		 5lg3A-1fuiA:
20.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6APH_A_ADNA501_2
(ADENOSYLHOMOCYSTEINA
SE)		 1fui L-FUCOSE ISOMERASE
(Escherichia
coli) 		4 / 5 THR A 375
THR A 364
HIS A 389
LEU A 483
 None
 1.32A 6aphA-1fuiA:
5.0		 6aphA-1fuiA:
21.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6DWD_B_GLYB709_0
(DEOXYNUCLEOSIDE
TRIPHOSPHATE
TRIPHOSPHOHYDROLASE
SAMHD1)		 1fui L-FUCOSE ISOMERASE
(Escherichia
coli) 		4 / 5 GLY A  17
ASP A  16
ARG A  19
ARG A  18
 None
 1.36A 6dwdB-1fuiA:
0.0
6dwdD-1fuiA:
0.0		 6dwdB-1fuiA:
20.65
6dwdD-1fuiA:
20.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6FGD_A_ACTA826_0
(GEPHYRIN)		 1fui L-FUCOSE ISOMERASE
(Escherichia
coli) 		3 / 3 HIS A 554
ARG A 563
ILE A 541
 None
 0.83A 6fgdA-1fuiA:
4.0		 6fgdA-1fuiA:
21.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6GBN_B_ADNB501_2
(-)		 1fui L-FUCOSE ISOMERASE
(Escherichia
coli) 		4 / 5 THR A 375
THR A 364
HIS A 389
LEU A 483
 None
 1.31A 6gbnB-1fuiA:
6.2		 6gbnB-1fuiA:
21.88