SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '1fuj'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1LIN_A_TFPA154_1
(CALMODULIN)		 1fuj PR3
(Homo
sapiens) 		4 / 7 LEU A 137
MET A 139
GLU A 157
LEU A 155
 FUC  A 245 (-4.0A)
None
None
None
 1.12A 1linA-1fujA:
undetectable		 1linA-1fujA:
18.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1N49_D_RITD401_1
(PROTEASE)		 1fuj PR3
(Homo
sapiens) 		6 / 11 GLY A  44
VAL A 121
ILE A 200
GLY A 211
PRO A 124
ILE A  47
 None
None
FUC  A 245 (-4.3A)
None
None
None
 1.37A 1n49C-1fujA:
undetectable		 1n49C-1fujA:
19.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1NT2_A_SAMA301_0
(FIBRILLARIN-LIKE
PRE-RRNA PROCESSING
PROTEIN)		 1fuj PR3
(Homo
sapiens) 		5 / 12 GLY A 140
SER A  32
SER A 195
ALA A 138
ILE A  16
 None
 1.20A 1nt2A-1fujA:
undetectable		 1nt2A-1fujA:
21.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1T88_A_CAMA1422_0
(CYTOCHROME P450-CAM)		 1fuj PR3
(Homo
sapiens) 		4 / 7 PHE A 228
GLY A 193
VAL A 216
ASP A 226
 None
 0.99A 1t88A-1fujA:
undetectable		 1t88A-1fujA:
22.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2DPM_A_SAMA300_0
(PROTEIN
(ADENINE-SPECIFIC
METHYLTRANSFERASE
DPNII 1))		 1fuj PR3
(Homo
sapiens) 		5 / 12 GLY A 140
PHE A  41
GLY A 193
GLY A 142
ALA A 152
 None
 1.03A 2dpmA-1fujA:
undetectable		 2dpmA-1fujA:
19.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2OXT_D_SAMD300_0
(NUCLEOSIDE-2'-O-METH
YLTRANSFERASE)		 1fuj PR3
(Homo
sapiens) 		6 / 12 GLY A 142
GLY A  44
GLY A 196
GLY A 193
THR A  54
LEU A  53
 None
 1.35A 2oxtD-1fujA:
undetectable		 2oxtD-1fujA:
19.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2XFH_A_CL6A1414_1
(ERYTHROMYCIN B/D
C-12 HYDROXYLASE)		 1fuj PR3
(Homo
sapiens) 		5 / 8 LEU A  59
GLN A  63
LEU A  33
THR A  54
LEU A 104
 None
 1.37A 2xfhA-1fujA:
undetectable		 2xfhA-1fujA:
19.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BOG_C_DVAC59_0
(6.5 KDA GLYCINE-RICH
ANTIFREEZE PROTEIN)		 1fuj PR3
(Homo
sapiens) 		3 / 3 GLY A 197
GLY A 193
GLY A  43
 None
 0.38A 3bogC-1fujA:
undetectable		 3bogC-1fujA:
16.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3EEO_A_SAMA328_1
(MODIFICATION
METHYLASE HHAI)		 1fuj PR3
(Homo
sapiens) 		3 / 3 GLU A  77
SER A 117
VAL A 118
 None
 0.68A 3eeoA-1fujA:
undetectable		 3eeoA-1fujA:
19.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3EL0_A_1UNA201_2
(PROTEASE)		 1fuj PR3
(Homo
sapiens) 		5 / 9 VAL A 121
ILE A 200
GLY A 211
PRO A 124
ILE A  47
 None
FUC  A 245 (-4.3A)
None
None
None
 0.93A 3el0B-1fujA:
undetectable		 3el0B-1fujA:
19.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3GWX_A_EPAA1_1
(PROTEIN (PEROXISOME
PROLIFERATOR
ACTIVATED RECEPTOR
(PPAR-DELTA)))		 1fuj PR3
(Homo
sapiens) 		5 / 10 VAL A  88
LEU A  33
VAL A  66
VAL A  64
LEU A  59
 None
 0.96A 3gwxA-1fujA:
undetectable		 3gwxA-1fujA:
19.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3UY4_A_PAUA302_0
(PANTOTHENATE
SYNTHETASE)		 1fuj PR3
(Homo
sapiens) 		4 / 8 GLN A  80
HIS A  82
VAL A  67
GLN A  34
 None
 1.02A 3uy4A-1fujA:
undetectable		 3uy4A-1fujA:
19.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4FAK_A_SAMA201_0
(RIBOSOMAL RNA LARGE
SUBUNIT
METHYLTRANSFERASE H)		 1fuj PR3
(Homo
sapiens) 		5 / 10 LEU A  53
ILE A 106
ILE A 212
GLY A 197
GLY A  43
 None
 0.97A 4fakA-1fujA:
undetectable		 4fakA-1fujA:
20.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4X3M_B_ADNB301_1
(RNA 2'-O RIBOSE
METHYLTRANSFERASE)		 1fuj PR3
(Homo
sapiens) 		5 / 9 PRO A 198
LEU A  33
ILE A 212
LEU A  53
THR A  54
 None
 1.26A 4x3mB-1fujA:
undetectable		 4x3mB-1fujA:
21.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ZME_A_ADNA1002_1
(MYOSIN HEAVY CHAIN
KINASE A)		 1fuj PR3
(Homo
sapiens) 		5 / 11 ALA A  86
LEU A 104
LEU A 105
PHE A  51
THR A 241
 None
 0.91A 4zmeA-1fujA:
0.0		 4zmeA-1fujA:
19.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ZME_B_ADNB902_1
(MYOSIN HEAVY CHAIN
KINASE A)		 1fuj PR3
(Homo
sapiens) 		5 / 10 ALA A  86
LEU A 104
LEU A 105
PHE A  51
THR A 241
 None
 0.91A 4zmeB-1fujA:
0.0		 4zmeB-1fujA:
19.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5AXD_C_RBVC502_2
(ADENOSYLHOMOCYSTEINA
SE)		 1fuj PR3
(Homo
sapiens) 		3 / 3 THR A 229
HIS A  48
LEU A 123
 None
 0.83A 5axdC-1fujA:
undetectable		 5axdC-1fujA:
19.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EIW_C_SAMC4000_0
(NS5
METHYLTRANSFERASE)		 1fuj PR3
(Homo
sapiens) 		6 / 12 GLY A 142
GLY A  44
GLY A 196
GLY A 193
THR A  54
VAL A  52
 None
 1.20A 5eiwC-1fujA:
undetectable		 5eiwC-1fujA:
21.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5IFU_B_GBMB801_1
(PROLINE--TRNA LIGASE)		 1fuj PR3
(Homo
sapiens) 		5 / 9 ILE A 190
THR A 229
ARG A 230
ILE A 212
GLY A 211
 None
 1.25A 5ifuB-1fujA:
undetectable		 5ifuB-1fujA:
17.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5UUN_A_ACTA309_0
(GLUTATHIONE
S-TRANSFERASE-LIKE
PROTEIN)		 1fuj PR3
(Homo
sapiens) 		4 / 4 LEU A  68
GLY A  69
SER A 117
SER A 115
 None
 1.18A 5uunA-1fujA:
0.0		 5uunA-1fujA:
18.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5UUN_B_ACTB306_0
(GLUTATHIONE
S-TRANSFERASE-LIKE
PROTEIN)		 1fuj PR3
(Homo
sapiens) 		4 / 4 LEU A  68
GLY A  69
SER A 117
SER A 115
 None
 1.17A 5uunB-1fujA:
undetectable		 5uunB-1fujA:
18.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6CK2_C_IPHC101_0
(INSULIN A CHAIN
INSULIN B CHAIN)		 1fuj PR3
(Homo
sapiens) 		4 / 4 ILE A 106
LEU A  68
HIS A  48
ALA A 112
 None
 0.92A 6ck2C-1fujA:
undetectable
6ck2D-1fujA:
undetectable		 6ck2C-1fujA:
10.23
6ck2D-1fujA:
9.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6GB9_A_ACTA508_0
(MOLYBDOPTERIN
BIOSYNTHESIS PROTEIN
CNX1)		 1fuj PR3
(Homo
sapiens) 		3 / 3 VAL A  67
ALA A  70
GLN A  34
 None
 0.67A 6gb9A-1fujA:
undetectable		 6gb9A-1fujA:
18.98