SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '1fuu'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1A7Y_B_DVAB2_0
(ACTINOMYCIN D)		 1fuu YEAST INITIATION
FACTOR 4A
(Saccharomyces
cerevisiae) 		3 / 3 THR A 194
PRO A 192
THR A 193
 None
 0.87A 1a7yB-1fuuA:
undetectable		 1a7yB-1fuuA:
2.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1I3W_E_DVAE8_0
(ACTINOMYCIN D)		 1fuu YEAST INITIATION
FACTOR 4A
(Saccharomyces
cerevisiae) 		3 / 3 THR A 193
THR A 194
PRO A 192
 None
 0.87A 1i3wE-1fuuA:
undetectable		 1i3wE-1fuuA:
2.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1I3W_F_DVAF8_0
(ACTINOMYCIN D)		 1fuu YEAST INITIATION
FACTOR 4A
(Saccharomyces
cerevisiae) 		3 / 3 THR A 193
THR A 194
PRO A 192
 None
 0.86A 1i3wF-1fuuA:
undetectable		 1i3wF-1fuuA:
2.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1MNV_D_DVAD2_0
(ACTINOMYCIN D)		 1fuu YEAST INITIATION
FACTOR 4A
(Saccharomyces
cerevisiae) 		3 / 3 THR A 194
PRO A 192
THR A 193
 None
 0.84A 1mnvD-1fuuA:
undetectable		 1mnvD-1fuuA:
2.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1MNV_D_DVAD8_0
(ACTINOMYCIN D)		 1fuu YEAST INITIATION
FACTOR 4A
(Saccharomyces
cerevisiae) 		3 / 3 THR A 193
THR A 194
PRO A 192
 None
 0.81A 1mnvD-1fuuA:
undetectable		 1mnvD-1fuuA:
2.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1RJD_A_SAMA801_0
(CARBOXY METHYL
TRANSFERASE FOR
PROTEIN PHOSPHATASE
2A CATALYTIC SUBUNIT)		 1fuu YEAST INITIATION
FACTOR 4A
(Saccharomyces
cerevisiae) 		5 / 12 ILE A 105
ALA A  65
GLY A  73
GLY A  70
LEU A 112
 None
 1.10A 1rjdA-1fuuA:
4.5		 1rjdA-1fuuA:
22.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1UOB_A_PNNA1311_0
(DEACETOXYCEPHALOSPOR
IN C SYNTHETASE)		 1fuu YEAST INITIATION
FACTOR 4A
(Saccharomyces
cerevisiae) 		5 / 12 LEU A 190
LEU A  62
VAL A 196
PHE A 187
ILE A 183
 None
 1.25A 1uobA-1fuuA:
undetectable		 1uobA-1fuuA:
18.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3IK3_B_0LIB2_2
(PROTO-ONCOGENE
TYROSINE-PROTEIN
KINASE ABL1)		 1fuu YEAST INITIATION
FACTOR 4A
(Saccharomyces
cerevisiae) 		4 / 7 LEU A 101
VAL A  61
ILE A 167
ARG A  50
 None
 1.30A 3ik3B-1fuuA:
undetectable		 3ik3B-1fuuA:
19.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3MBH_E_PXLE400_1
(PUTATIVE
PHOSPHOMETHYLPYRIMID
INE KINASE)		 1fuu YEAST INITIATION
FACTOR 4A
(Saccharomyces
cerevisiae) 		5 / 12 ASP A 169
LEU A 199
THR A  74
GLN A  48
VAL A 108
 None
 1.48A 3mbhE-1fuuA:
3.6		 3mbhE-1fuuA:
23.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3S79_A_ASDA601_1
(CYTOCHROME P450 19A1)		 1fuu YEAST INITIATION
FACTOR 4A
(Saccharomyces
cerevisiae) 		5 / 12 ILE A 167
VAL A 210
LEU A 208
MET A 203
LEU A  62
 None
 1.23A 3s79A-1fuuA:
undetectable		 3s79A-1fuuA:
21.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3VW1_D_CVID301_0
(PUTATIVE REGULATORY
PROTEIN)		 1fuu YEAST INITIATION
FACTOR 4A
(Saccharomyces
cerevisiae) 		5 / 12 LEU A 199
THR A  14
ILE A 221
ILE A 167
ALA A  79
 None
 1.14A 3vw1D-1fuuA:
undetectable		 3vw1D-1fuuA:
21.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4HIV_D_DVAD2_0
(ACTINOMYCIN D)		 1fuu YEAST INITIATION
FACTOR 4A
(Saccharomyces
cerevisiae) 		3 / 3 THR A 194
PRO A 192
THR A 193
 None
 0.80A 4hivD-1fuuA:
undetectable		 4hivD-1fuuA:
2.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4L3G_F_ACTF401_0
(METHYLAMINE
DEHYDROGENASE HEAVY
CHAIN)		 1fuu YEAST INITIATION
FACTOR 4A
(Saccharomyces
cerevisiae) 		3 / 3 ARG A  34
LEU A  33
GLU A  30
 None
 0.66A 4l3gF-1fuuA:
undetectable		 4l3gF-1fuuA:
24.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4N09_D_ADND401_2
(ADENOSINE KINASE)		 1fuu YEAST INITIATION
FACTOR 4A
(Saccharomyces
cerevisiae) 		4 / 5 CYH A 123
LEU A  93
LEU A 189
LEU A  95
 None
 1.04A 4n09D-1fuuA:
4.2		 4n09D-1fuuA:
22.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QN9_B_DXCB610_0
(N-ACYL-PHOSPHATIDYLE
THANOLAMINE-HYDROLYZ
ING PHOSPHOLIPASE D)		 1fuu YEAST INITIATION
FACTOR 4A
(Saccharomyces
cerevisiae) 		3 / 3 GLY A 147
PRO A 146
ALA A  96
 None
 0.52A 4qn9B-1fuuA:
0.7		 4qn9B-1fuuA:
21.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5JKV_A_ASDA602_1
(AROMATASE)		 1fuu YEAST INITIATION
FACTOR 4A
(Saccharomyces
cerevisiae) 		5 / 12 ILE A 167
VAL A 210
LEU A 208
MET A 203
LEU A  62
 None
 1.21A 5jkvA-1fuuA:
undetectable		 5jkvA-1fuuA:
21.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6J20_A_GBQA1201_0
(SUBSTANCE-P
RECEPTOR,ENDOLYSIN)		 1fuu YEAST INITIATION
FACTOR 4A
(Saccharomyces
cerevisiae) 		5 / 12 PRO A 146
VAL A 149
ILE A 153
PHE A 166
PHE A 187
 None
 1.01A 6j20A-1fuuA:
0.0		 6j20A-1fuuA:
22.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6J20_A_GBQA1201_1
(SUBSTANCE-P
RECEPTOR,ENDOLYSIN)		 1fuu YEAST INITIATION
FACTOR 4A
(Saccharomyces
cerevisiae) 		4 / 7 ILE A  77
GLN A  48
GLU A  43
VAL A  36
 None
 1.05A 6j20A-1fuuA:
0.0		 6j20A-1fuuA:
22.90