SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '1fvg'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2AVD_A_SAMA501_0
(CATECHOL-O-METHYLTRA
NSFERASE)		 1fvg PEPTIDE METHIONINE
SULFOXIDE REDUCTASE
(Bos
taurus) 		5 / 12 GLY A  69
ALA A 114
ALA A 158
ASP A 192
TYR A 160
 None
 1.17A 2avdA-1fvgA:
undetectable		 2avdA-1fvgA:
21.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2XZ5_D_ACHD1211_0
(SOLUBLE
ACETYLCHOLINE
RECEPTOR)		 1fvg PEPTIDE METHIONINE
SULFOXIDE REDUCTASE
(Bos
taurus) 		4 / 8 THR A 111
GLN A 154
SER A 108
CYH A 107
 None
 1.03A 2xz5C-1fvgA:
0.0
2xz5D-1fvgA:
0.0		 2xz5C-1fvgA:
22.67
2xz5D-1fvgA:
22.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5N4T_A_BEZA507_0
(BETA-LACTAMASE VIM-2)		 1fvg PEPTIDE METHIONINE
SULFOXIDE REDUCTASE
(Bos
taurus) 		3 / 3 THR A  89
HIS A  48
ASN A  53
 None
 0.90A 5n4tA-1fvgA:
undetectable		 5n4tA-1fvgA:
22.75