SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '1fvi'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2E5D_A_NCAA1501_0
(NICOTINAMIDE
PHOSPHORIBOSYLTRANSF
ERASE)		 1fvi CHLORELLA VIRUS DNA
LIGASE-ADENYLATE
(Chlorella
virus) 		4 / 7 ARG A  32
ASP A  99
ASP A  65
TYR A 172
 AMP  A 501 (-4.2A)
None
None
None
 1.06A 2e5dA-1fviA:
undetectable
2e5dB-1fviA:
undetectable		 2e5dA-1fviA:
20.38
2e5dB-1fviA:
20.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2E5D_B_NCAB1502_0
(NICOTINAMIDE
PHOSPHORIBOSYLTRANSF
ERASE)		 1fvi CHLORELLA VIRUS DNA
LIGASE-ADENYLATE
(Chlorella
virus) 		4 / 7 ASP A  65
TYR A 172
ARG A  32
ASP A  99
 None
None
AMP  A 501 (-4.2A)
None
 1.08A 2e5dA-1fviA:
undetectable
2e5dB-1fviA:
undetectable		 2e5dA-1fviA:
20.38
2e5dB-1fviA:
20.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3GAN_A_SVRA158_1
(UNCHARACTERIZED
PROTEIN AT3G22680)		 1fvi CHLORELLA VIRUS DNA
LIGASE-ADENYLATE
(Chlorella
virus) 		5 / 11 TYR A 109
VAL A 113
PRO A 139
ILE A 165
PRO A  26
 None
None
None
None
AMP  A 501 (-4.8A)
 1.41A 3ganA-1fviA:
undetectable		 3ganA-1fviA:
20.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4YIA_B_IMNB401_2
(THYROXINE-BINDING
GLOBULIN)		 1fvi CHLORELLA VIRUS DNA
LIGASE-ADENYLATE
(Chlorella
virus) 		3 / 3 LEU A 149
ARG A 153
ARG A 285
 None
 0.90A 4yiaB-1fviA:
0.0		 4yiaB-1fviA:
7.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5Y9Y_A_ACTA409_0
(UNCHARACTERIZED
PROTEIN KDOO)		 1fvi CHLORELLA VIRUS DNA
LIGASE-ADENYLATE
(Chlorella
virus) 		3 / 3 LYS A 167
PRO A 168
LYS A 108
 None
 0.93A 5y9yA-1fviA:
0.0		 5y9yA-1fviA:
21.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6AG0_A_ACRA605_0
(ALPHA-AMYLASE)		 1fvi CHLORELLA VIRUS DNA
LIGASE-ADENYLATE
(Chlorella
virus) 		4 / 8 GLY A 291
ILE A 292
ASP A 252
ASP A 254
 None
 0.90A 6ag0A-1fviA:
undetectable		 6ag0A-1fviA:
18.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6AG0_C_ACRC605_0
(ALPHA-AMYLASE)		 1fvi CHLORELLA VIRUS DNA
LIGASE-ADENYLATE
(Chlorella
virus) 		4 / 8 GLY A 291
ILE A 292
ASP A 252
ASP A 254
 None
 0.85A 6ag0C-1fviA:
undetectable		 6ag0C-1fviA:
18.64