SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '1fvp'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2QMJ_A_ACRA1001_1
(MALTASE-GLUCOAMYLASE
, INTESTINAL)		 1fvp FLAVOPROTEIN 390
(Photobacterium
phosphoreum) 		5 / 12 ILE A 168
ASP A  97
ASP A  48
PHE A   9
HIS A 131
 None
 1.39A 2qmjA-1fvpA:
undetectable		 2qmjA-1fvpA:
14.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2W9G_A_TOPA1159_1
(DIHYDROFOLATE
REDUCTASE)		 1fvp FLAVOPROTEIN 390
(Photobacterium
phosphoreum) 		5 / 10 LEU A 130
LEU A 217
LEU A 181
VAL A 184
PHE A 197
 None
FMA  A 233 ( 4.8A)
FMA  A 233 (-4.3A)
FMA  A 233 (-4.2A)
None
 1.05A 2w9gA-1fvpA:
undetectable		 2w9gA-1fvpA:
21.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2XF3_B_J01B500_1
(ORF12)		 1fvp FLAVOPROTEIN 390
(Photobacterium
phosphoreum) 		5 / 9 HIS A 126
VAL A 124
ILE A 121
LEU A 106
ALA A  76
 None
 1.45A 2xf3B-1fvpA:
0.0		 2xf3B-1fvpA:
18.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2XFS_B_J01B500_1
(ORF12)		 1fvp FLAVOPROTEIN 390
(Photobacterium
phosphoreum) 		5 / 9 HIS A 126
VAL A 124
ILE A 121
LEU A 106
ALA A  76
 None
 1.47A 2xfsB-1fvpA:
0.0		 2xfsB-1fvpA:
18.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2XH9_B_J01B1436_1
(ORF12)		 1fvp FLAVOPROTEIN 390
(Photobacterium
phosphoreum) 		5 / 9 HIS A 126
VAL A 124
ILE A 121
LEU A 106
ALA A  76
 None
 1.44A 2xh9B-1fvpA:
0.0		 2xh9B-1fvpA:
18.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2XRZ_A_ACTA1467_0
(DEOXYRIBODIPYRIMIDIN
E PHOTOLYASE)		 1fvp FLAVOPROTEIN 390
(Photobacterium
phosphoreum) 		4 / 5 ARG A  33
ASP A  38
ILE A 215
GLU A  30
 None
 1.13A 2xrzA-1fvpA:
0.5
2xrzB-1fvpA:
undetectable		 2xrzA-1fvpA:
18.37
2xrzB-1fvpA:
18.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3CKZ_A_ZMRA469_2
(NEURAMINIDASE)		 1fvp FLAVOPROTEIN 390
(Photobacterium
phosphoreum) 		4 / 6 ASP A  98
TRP A  96
ILE A 168
SER A 164
 None
 1.25A 3ckzA-1fvpA:
undetectable		 3ckzA-1fvpA:
19.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3PHA_A_ACRA701_1
(ALPHA-GLUCOSIDASE)		 1fvp FLAVOPROTEIN 390
(Photobacterium
phosphoreum) 		5 / 12 ILE A 168
ASP A  97
ASP A  48
PHE A   9
HIS A 131
 None
 1.41A 3phaA-1fvpA:
undetectable		 3phaA-1fvpA:
17.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3PHA_B_ACRB701_1
(ALPHA-GLUCOSIDASE)		 1fvp FLAVOPROTEIN 390
(Photobacterium
phosphoreum) 		5 / 12 ILE A 168
ASP A  97
ASP A  48
PHE A   9
HIS A 131
 None
 1.42A 3phaB-1fvpA:
undetectable		 3phaB-1fvpA:
17.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3TOP_A_ACRA1_1
(MALTASE-GLUCOAMYLASE
, INTESTINAL)		 1fvp FLAVOPROTEIN 390
(Photobacterium
phosphoreum) 		5 / 12 ILE A 168
ASP A  97
ASP A  48
PHE A   9
HIS A 131
 None
 1.49A 3topA-1fvpA:
undetectable		 3topA-1fvpA:
13.98
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3TOP_B_ACRB1_1
(MALTASE-GLUCOAMYLASE
, INTESTINAL)		 1fvp FLAVOPROTEIN 390
(Photobacterium
phosphoreum) 		5 / 12 ILE A 168
ASP A  97
ASP A  48
PHE A   9
HIS A 131
 None
 1.49A 3topB-1fvpA:
2.6		 3topB-1fvpA:
13.98
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3W37_A_ACRA1001_1
(ALPHA-GLUCOSIDASE)		 1fvp FLAVOPROTEIN 390
(Photobacterium
phosphoreum) 		5 / 12 ILE A 168
ASP A  97
ASP A  48
PHE A   9
HIS A 131
 None
 1.47A 3w37A-1fvpA:
undetectable		 3w37A-1fvpA:
13.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3WEL_A_ACRA1001_1
(ALPHA-GLUCOSIDASE)		 1fvp FLAVOPROTEIN 390
(Photobacterium
phosphoreum) 		5 / 12 ILE A 168
ASP A  97
ASP A  48
PHE A   9
HIS A 131
 None
 1.47A 3welA-1fvpA:
undetectable		 3welA-1fvpA:
13.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4B9Z_A_ACRA1818_1
(ALPHA-GLUCOSIDASE,
PUTATIVE, ADG31B)		 1fvp FLAVOPROTEIN 390
(Photobacterium
phosphoreum) 		5 / 12 ILE A 168
ASP A  97
ASP A  48
PHE A   9
HIS A 131
 None
 1.45A 4b9zA-1fvpA:
undetectable		 4b9zA-1fvpA:
14.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4Y8W_C_STRC603_2
(CYTOCHROME P450
21-HYDROXYLASE)		 1fvp FLAVOPROTEIN 390
(Photobacterium
phosphoreum) 		3 / 3 LEU A 199
VAL A  44
ASP A  43
 None
 0.67A 4y8wC-1fvpA:
0.0		 4y8wC-1fvpA:
18.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5NN8_A_ACRA1015_1
(LYSOSOMAL
ALPHA-GLUCOSIDASE)		 1fvp FLAVOPROTEIN 390
(Photobacterium
phosphoreum) 		5 / 12 ILE A 168
ASP A  97
ASP A  48
PHE A   9
HIS A 131
 None
 1.49A 5nn8A-1fvpA:
undetectable		 5nn8A-1fvpA:
13.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5X7P_A_ACRA1401_1
(GLYCOSIDE HYDROLASE
FAMILY 31
ALPHA-GLUCOSIDASE)		 1fvp FLAVOPROTEIN 390
(Photobacterium
phosphoreum) 		5 / 10 ASP A  97
ASP A  48
PHE A   9
ASN A  46
HIS A 131
 None
 1.46A 5x7pA-1fvpA:
undetectable		 5x7pA-1fvpA:
10.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6CI6_A_NBOA607_1
(SERUM ALBUMIN)		 1fvp FLAVOPROTEIN 390
(Photobacterium
phosphoreum) 		4 / 7 ASN A 111
ALA A 112
GLU A  79
LEU A 107
 None
 1.00A 6ci6A-1fvpA:
undetectable		 6ci6A-1fvpA:
25.17