SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '1fxz'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1N2X_A_SAMA401_0
(S-ADENOSYL-METHYLTRA
NSFERASE MRAW)		 1fxz GLYCININ G1
(Glycine
max) 		5 / 12 GLY A  68
GLU A 153
GLY A 128
VAL A  48
ASP A 148
 None
 1.32A 1n2xA-1fxzA:
undetectable		 1n2xA-1fxzA:
18.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1SDT_B_MK1B902_2
(PROTEASE RETROPEPSIN)		 1fxz GLYCININ G1
(Glycine
max) 		5 / 12 GLY A  47
ALA A  46
ILE A  14
VAL A 392
ILE A 394
 None
 0.95A 1sdtB-1fxzA:
undetectable		 1sdtB-1fxzA:
11.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2Q72_A_IXXA802_1
(TRANSPORTER)		 1fxz GLYCININ G1
(Glycine
max) 		4 / 6 ILE A 306
ARG A 303
ILE A  72
PHE A 415
 None
 1.15A 2q72A-1fxzA:
undetectable		 2q72A-1fxzA:
21.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2V0M_A_KLNA1500_1
(CYTOCHROME P450 3A4)		 1fxz GLYCININ G1
(Glycine
max) 		5 / 11 SER A 145
ILE A  72
PHE A 117
GLU A  34
LEU A  55
 None
 1.44A 2v0mA-1fxzA:
0.0		 2v0mA-1fxzA:
22.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3EM4_V_DR7V100_1
(PROTEASE)		 1fxz GLYCININ G1
(Glycine
max) 		5 / 11 GLY A  47
ALA A  46
ILE A  14
VAL A 392
ILE A 394
 None
 0.92A 3em4U-1fxzA:
undetectable		 3em4U-1fxzA:
13.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3FPJ_A_SAMA301_1
(PUTATIVE
UNCHARACTERIZED
PROTEIN)		 1fxz GLYCININ G1
(Glycine
max) 		4 / 6 GLY A  77
THR A  54
GLU A 119
GLU A 411
 None
 1.05A 3fpjA-1fxzA:
undetectable		 3fpjA-1fxzA:
20.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3SFU_B_RBVB601_1
(RNA POLYMERASE)		 1fxz GLYCININ G1
(Glycine
max) 		5 / 9 THR A  66
ASN A  67
GLY A  68
ASP A 148
LEU A 338
 None
 1.37A 3sfuB-1fxzA:
undetectable		 3sfuB-1fxzA:
21.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4UXQ_A_0LIA1752_2
(FIBROBLAST GROWTH
FACTOR RECEPTOR 4)		 1fxz GLYCININ G1
(Glycine
max) 		4 / 7 VAL A 392
ILE A 146
ALA A  46
ILE A 147
 None
 0.84A 4uxqA-1fxzA:
undetectable		 4uxqA-1fxzA:
20.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5W7B_B_PA1B204_1
(ACYLOXYACYL
HYDROLASE SMALL
SUBUNIT
ACYLOXYACYL
HYDROLASE LARGE
SUBUNIT)		 1fxz GLYCININ G1
(Glycine
max) 		3 / 3 GLY A 199
ASN A 168
ARG A  62
 None
 0.79A 5w7bD-1fxzA:
undetectable		 5w7bD-1fxzA:
11.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6BAA_E_GBME2001_2
(ATP-BINDING CASSETTE
SUB-FAMILY C MEMBER
8)		 1fxz GLYCININ G1
(Glycine
max) 		3 / 3 LEU A 338
THR A  66
ASN A  67
 None
 0.73A 6baaE-1fxzA:
0.0		 6baaE-1fxzA:
13.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6BAA_F_GBMF2001_2
(ATP-BINDING CASSETTE
SUB-FAMILY C MEMBER
8)		 1fxz GLYCININ G1
(Glycine
max) 		3 / 3 LEU A 338
THR A  66
ASN A  67
 None
 0.73A 6baaF-1fxzA:
0.0		 6baaF-1fxzA:
13.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6BAA_G_GBMG2001_2
(ATP-BINDING CASSETTE
SUB-FAMILY C MEMBER
8)		 1fxz GLYCININ G1
(Glycine
max) 		3 / 3 LEU A 338
THR A  66
ASN A  67
 None
 0.73A 6baaG-1fxzA:
0.0		 6baaG-1fxzA:
13.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6BAA_H_GBMH2001_2
(ATP-BINDING CASSETTE
SUB-FAMILY C MEMBER
8)		 1fxz GLYCININ G1
(Glycine
max) 		3 / 3 LEU A 338
THR A  66
ASN A  67
 None
 0.73A 6baaH-1fxzA:
0.0		 6baaH-1fxzA:
13.99