SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '1fyv'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)

Filter list by:

	DrReposER ID / Desc.	Hit PDBID	Hit Macromolecule	Res. Matches	Interface	HETATM	RMSD	Dali Z-score	Seq. Identity (%)	View	Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1R15_C_NCAC439_0 (ADP-RIBOSYL CYCLASE)	1fyv	TOLL-LIKE RECEPTOR 1 (Homo sapiens)	3 / 3	TRP A 758 PHE A 768 TRP A 769	None	1.22A	1r15C-1fyvA: 0.0	1r15C-1fyvA: 21.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1R15_F_NCAF469_0 (ADP-RIBOSYL CYCLASE)	1fyv	TOLL-LIKE RECEPTOR 1 (Homo sapiens)	3 / 3	TRP A 758 PHE A 768 TRP A 769	None	1.21A	1r15F-1fyvA: 0.0	1r15F-1fyvA: 21.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1R15_G_NCAG479_0 (ADP-RIBOSYL CYCLASE)	1fyv	TOLL-LIKE RECEPTOR 1 (Homo sapiens)	3 / 3	TRP A 758 PHE A 768 TRP A 769	None	1.22A	1r15G-1fyvA: 0.0	1r15G-1fyvA: 21.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1R15_H_NCAH489_0 (ADP-RIBOSYL CYCLASE)	1fyv	TOLL-LIKE RECEPTOR 1 (Homo sapiens)	3 / 3	TRP A 758 PHE A 768 TRP A 769	None	1.22A	1r15H-1fyvA: 0.0	1r15H-1fyvA: 21.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1U18_A_HSMA401_1 (NITROPHORIN 1)	1fyv	TOLL-LIKE RECEPTOR 1 (Homo sapiens)	4 / 4	ASP A 647 LEU A 730 LEU A 697 LEU A 731	None	1.23A	1u18A-1fyvA: 0.0	1u18A-1fyvA: 17.41

[["DrReposER ID","Desc.","Hit PDB","Hit molecule","Hit organism","Res. no.","Interface","HETATM","RMSD","Z-score","Seq ID"],["1R15_C_NCAC439_0","ADP-RIBOSYL CYCLASE","1fyv","TOLL-LIKE RECEPTOR 1","Homo sapiens",3,"TRP A 758;PHE A 768;TRP A 769","None","1.22A","1r15C-1fyvA:0.0","1r15C-1fyvA:21.18"],["1R15_F_NCAF469_0","ADP-RIBOSYL CYCLASE","1fyv","TOLL-LIKE RECEPTOR 1","Homo sapiens",3,"TRP A 758;PHE A 768;TRP A 769","None","1.21A","1r15F-1fyvA:0.0","1r15F-1fyvA:21.18"],["1R15_G_NCAG479_0","ADP-RIBOSYL CYCLASE","1fyv","TOLL-LIKE RECEPTOR 1","Homo sapiens",3,"TRP A 758;PHE A 768;TRP A 769","None","1.22A","1r15G-1fyvA:0.0","1r15G-1fyvA:21.18"],["1R15_H_NCAH489_0","ADP-RIBOSYL CYCLASE","1fyv","TOLL-LIKE RECEPTOR 1","Homo sapiens",3,"TRP A 758;PHE A 768;TRP A 769","None","1.22A","1r15H-1fyvA:0.0","1r15H-1fyvA:21.18"],["1U18_A_HSMA401_1","NITROPHORIN 1","1fyv","TOLL-LIKE RECEPTOR 1","Homo sapiens",4,"ASP A 647;LEU A 730;LEU A 697;LEU A 731","None","1.23A","1u18A-1fyvA:0.0","1u18A-1fyvA:17.41"]]