SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '1fzp'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)

Filter list by:

	DrReposER ID / Desc.	Hit PDBID	Hit Macromolecule	Res. Matches	Interface	HETATM	RMSD	Dali Z-score	Seq. Identity (%)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4OTW_A_DB8A1101_2 (RECEPTOR TYROSINE-PROTEIN KINASE ERBB-3)	1fzp	STAPHYLOCOCCAL ACCESSORY REGULATOR A (Staphylococcus aureus)	3 / 3	LEU D 95 LEU D 25 ASN D 85	None	0.67A	4otwA-1fzpD: undetectable	4otwA-1fzpD: 15.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4ZPH_A_PRLA501_0 (ARYL HYDROCARBON RECEPTOR NUCLEAR TRANSLOCATOR ENDOTHELIAL PAS DOMAIN-CONTAINING PROTEIN 1)	1fzp	STAPHYLOCOCCAL ACCESSORY REGULATOR A (Staphylococcus aureus)	4 / 7	VAL D 111 LEU D 107 SER D 106 GLU D 105	None	1.09A	4zphA-1fzpD: undetectable 4zphB-1fzpD: undetectable	4zphA-1fzpD: 16.18 4zphB-1fzpD: 15.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5NWV_A_ACAA18_1 (SCRFP-TAG,GP41)	1fzp	STAPHYLOCOCCAL ACCESSORY REGULATOR A (Staphylococcus aureus)	5 / 12	LEU D 53 SER D 33 GLU D 45 GLU D 50 LEU D 40	None	1.22A	5nwvA-1fzpD: 0.2	5nwvA-1fzpD: 16.22